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Chemical TNF-Related Apoptosis-Inducing Ligand

Name TNF-Related Apoptosis-Inducing Ligand
Equivalent Terms Antigen, CD253 | Apo 2 Ligand | Apo-2 Ligand | Apo 2L Protein | Apo-2L Protein | Apoptosis-Inducing Ligand, TNF-Related | CD253 Antigen | TNF Related Apoptosis Inducing Ligand | TNF Superfamily, Member 10 | TRAIL Protein | Tumor Necrosis Factor Ligand Superfamily Member 10
Definition A transmembrane-protein belonging to the TNF family of intercellular signaling proteins. It is a widely expressed ligand that activates APOPTOSIS by binding to TNF-RELATED APOPTOSIS-INDUCING LIGAND RECEPTORS. The membrane-bound form of the protein can be cleaved by specific CYSTEINE ENDOPEPTIDASES to form a soluble ligand form.
Curation Status No associations have been curated for this chemical yet.
MeSH® ID D053221
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Top ↑ Ancestors

ChemicalsBiological Factors Has associated genes Has associated diseases Has associated exposure references Intercellular Signaling Peptides and Proteins Has associated genes Has associated diseases Cytokines Has associated genes Has associated diseases Tumor Necrosis Factors TNF-Related Apoptosis-Inducing Ligand

Top ↑ Descendants

TNF-Related Apoptosis-Inducing Ligand
  AD-O53.2 fusion protein
  Fn14-TRAIL fusion protein, human
  TNFSF10 protein, human
  Tnfsf10 protein, mouse
  Tnfsf10 protein, rat