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Chemical Transforming Growth Factor beta1

Name Transforming Growth Factor beta1
Equivalent Terms Latency-Associated Protein, TGF-beta1 | TGF beta 1 | TGF-beta1 | TGF-beta-1 | TGF beta1LAP | TGF-beta1LAP | TGF beta1 Latency Associated Protein | TGF-beta1 Latency-Associated Protein | Transforming Growth Factor beta 1 Latency Associated Peptide | Transforming Growth Factor beta I
Definition A subtype of transforming growth factor beta that is synthesized by a wide variety of cells. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta 1 and TGF-beta1 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor. Defects in the gene that encodes TGF-beta1 are the cause of CAMURATI-ENGELMANN SYNDROME.
Curation Status No associations have been curated for this chemical yet.
MeSH® ID D053773
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Top ↑ Ancestors

1. ChemicalsBiological Factors Has associated genes Has associated diseases Has associated exposure references Intercellular Signaling Peptides and Proteins Has associated genes Has associated diseases Cytokines Has associated genes Has associated diseases Transforming Growth Factor beta Transforming Growth Factor beta1
2. ChemicalsBiological Factors Has associated genes Has associated diseases Has associated exposure references Intercellular Signaling Peptides and Proteins Has associated genes Has associated diseases TGF-beta Superfamily Proteins Transforming Growth Factor beta Transforming Growth Factor beta1

Top ↑ Descendants

Transforming Growth Factor beta1
  N-FLAG-TGF-beta1
  TGFB1 protein, human
  Tgfb1 protein, mouse
  Tgfb1 protein, rat
  TGFbeta1a protein, zebrafish
  transforming growth factor beta1 (41-65)