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Chemical Transforming Growth Factor beta2

Name Transforming Growth Factor beta2
Equivalent Terms BSC 1 Cell Growth Inhibitor | BSC-1 Cell Growth Inhibitor | Cartilage Inducing Factor B | Cartilage-Inducing Factor-B | Glioblastoma Derived T Cell Suppressor Factor | Glioblastoma-Derived T-Cell Suppressor Factor | Latency-Associated Protein, TGF-beta2 | Polyergin | Suppressor Factor, T-Cell, Glioblastoma-Derived | TGF-beta2 | TGF-beta-2 | TGF beta2LAP | TGF-beta2LAP | TGF beta2 Latency Associated Protein | TGF-beta2 Latency-Associated Protein | Transforming Growth Factor beta 2 Latency Associated Peptide
Definition A TGF-beta subtype that was originally identified as a GLIOBLASTOMA-derived factor which inhibits the antigen-dependent growth of both helper and CYTOTOXIC T LYMPHOCYTES. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta2 and TGF-beta2 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor.
Curation Status No associations have been curated for this chemical yet.
MeSH® ID D053781
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Top ↑ Ancestors

1. ChemicalsBiological Factors Has associated genes Has associated diseases Has associated exposure references Intercellular Signaling Peptides and Proteins Has associated genes Has associated diseases Cytokines Has associated genes Has associated diseases Transforming Growth Factor beta Transforming Growth Factor beta2
2. ChemicalsBiological Factors Has associated genes Has associated diseases Has associated exposure references Intercellular Signaling Peptides and Proteins Has associated genes Has associated diseases TGF-beta Superfamily Proteins Transforming Growth Factor beta Transforming Growth Factor beta2

Top ↑ Descendants

Transforming Growth Factor beta2
  TGFB2 protein, human
  Tgfb2 protein, mouse
  Tgfb2 protein, rat