Skip navigation

Chemical Pentacyclic Triterpenes

1–50 of 183 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. 1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole apoptotic process Dithiothreitol Dithiothreitol inhibits the reaction [1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole results in increased apoptotic process] 1: Homo sapiens Cell Line, Tumor | Pancreas
13 genes: CASP3 | CASP8 | CASP9 | DIABLO | EGLN3 | HMOX1 | HTATIP2 | IER3 | IFNG | PLK3 | RASSF6 | TNF | TRIB3
1
2. 1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole apoptotic process 1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole results in increased apoptotic process 1: Homo sapiens Blood | Cell Line, Tumor
13 genes: CASP3 | CASP8 | CASP9 | DIABLO | EGLN3 | HMOX1 | HTATIP2 | IER3 | IFNG | PLK3 | RASSF6 | TNF | TRIB3
1
3. 1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole apoptotic process Bortezomib [1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole co-treated with Bortezomib] results in increased apoptotic process 1: Homo sapiens Blood | Tumor Cells, Cultured
13 genes: CASP3 | CASP8 | CASP9 | DIABLO | EGLN3 | HMOX1 | HTATIP2 | IER3 | IFNG | PLK3 | RASSF6 | TNF | TRIB3
1
4. 1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole regulation of mitochondrial membrane potential Dithiothreitol Dithiothreitol inhibits the reaction [1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole results in increased regulation of mitochondrial membrane potential] 1: Homo sapiens Cell Line, Tumor | Pancreas   1
5. 1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole regulation of mitochondrial membrane potential Bortezomib [Bortezomib co-treated with 1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole] results in decreased regulation of mitochondrial membrane potential 1: Homo sapiens Blood | Cell Line, Tumor   1
6. 1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole regulation of mitochondrial membrane potential Mercaptoethanol Mercaptoethanol inhibits the reaction [1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole results in increased regulation of mitochondrial membrane potential] 1: Homo sapiens Cell Line, Tumor | Pancreas   1
7. 1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole apoptotic process Bortezomib Bortezomib promotes the reaction [1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole results in increased apoptotic process] 1: Homo sapiens Blood | Cell Line, Tumor
13 genes: CASP3 | CASP8 | CASP9 | DIABLO | EGLN3 | HMOX1 | HTATIP2 | IER3 | IFNG | PLK3 | RASSF6 | TNF | TRIB3
1
8. 1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole apoptotic process Mercaptoethanol Mercaptoethanol inhibits the reaction [1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole results in increased apoptotic process] 1: Homo sapiens Cell Line, Tumor | Pancreas
13 genes: CASP3 | CASP8 | CASP9 | DIABLO | EGLN3 | HMOX1 | HTATIP2 | IER3 | IFNG | PLK3 | RASSF6 | TNF | TRIB3
1
9. 1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole apoptotic process 1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole results in increased apoptotic process 1: Homo sapiens Cells, Cultured
13 genes: CASP3 | CASP8 | CASP9 | DIABLO | EGLN3 | HMOX1 | HTATIP2 | IER3 | IFNG | PLK3 | RASSF6 | TNF | TRIB3
1
10. 1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole apoptotic process 1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole results in increased apoptotic process 1: Homo sapiens Bone Marrow | Stromal Cells
13 genes: CASP3 | CASP8 | CASP9 | DIABLO | EGLN3 | HMOX1 | HTATIP2 | IER3 | IFNG | PLK3 | RASSF6 | TNF | TRIB3
1
11. 1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole regulation of mitochondrial membrane potential Glutathione Glutathione inhibits the reaction [1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole results in increased regulation of mitochondrial membrane potential] 1: Homo sapiens Cell Line, Tumor | Pancreas   1
12. 1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole apoptotic process arsenic trioxide arsenic trioxide promotes the reaction [1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole results in increased apoptotic process] 1: Homo sapiens Cells, Cultured
13 genes: CASP3 | CASP8 | CASP9 | DIABLO | EGLN3 | HMOX1 | HTATIP2 | IER3 | IFNG | PLK3 | RASSF6 | TNF | TRIB3
1
13. 1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole apoptotic process 1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole results in increased apoptotic process 1: Homo sapiens Cell Line, Tumor | Pancreas
13 genes: CASP3 | CASP8 | CASP9 | DIABLO | EGLN3 | HMOX1 | HTATIP2 | IER3 | IFNG | PLK3 | RASSF6 | TNF | TRIB3
1
14. 1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole apoptotic process BCL2 | Bortezomib [1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole co-treated with Bortezomib] inhibits the reaction [BCL2 protein results in decreased apoptotic process] 1: Homo sapiens Blood | Cell Line, Tumor
13 genes: CASP3 | CASP8 | CASP9 | DIABLO | EGLN3 | HMOX1 | HTATIP2 | IER3 | IFNG | PLK3 | RASSF6 | TNF | TRIB3
1
15. 1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole cell proliferation 1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole results in decreased cell proliferation 1: Homo sapiens Cell Line, Tumor | Pancreas
10 genes: AR | CREG1 | ENTPD5 | GNAT1 | MYC | NRG1 | POLR3G | TNF | TXNRD1 | UCHL1
1
16. 1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole regulation of mitochondrial membrane potential 1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole results in decreased regulation of mitochondrial membrane potential 1: Homo sapiens Cell Line, Tumor | Pancreas   1
17. 1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole apoptotic process Glutathione Glutathione inhibits the reaction [1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole results in increased apoptotic process] 1: Homo sapiens Cell Line, Tumor | Pancreas
13 genes: CASP3 | CASP8 | CASP9 | DIABLO | EGLN3 | HMOX1 | HTATIP2 | IER3 | IFNG | PLK3 | RASSF6 | TNF | TRIB3
1
18. 18alpha-glycyrrhetinic acid lactate dehydrogenase activity Methotrexate 18alpha-glycyrrhetinic acid inhibits the reaction [Methotrexate results in increased lactate dehydrogenase activity] 1: Rattus norvegicus Serum   1
19. 18alpha-glycyrrhetinic acid gap junction channel activity 18alpha-glycyrrhetinic acid results in decreased gap junction channel activity 1: Rattus norvegicus Liver | Epithelial Cells | Cell Line   1
20. 18alpha-glycyrrhetinic acid cell proliferation 18alpha-glycyrrhetinic acid results in decreased cell proliferation 1: Homo sapiens Prostate | Cell Line, Tumor
4 genes: BAX | BCL2 | TNF | VEGFA
1
21. 18alpha-glycyrrhetinic acid regulation of membrane potential Phenylephrine 18alpha-glycyrrhetinic acid inhibits the reaction [Phenylephrine affects regulation of membrane potential] 1: Rodentia Aorta | Endothelium, Vascular   1
22. 18alpha-glycyrrhetinic acid alkaline phosphatase activity 1-Naphthylisothiocyanate 18alpha-glycyrrhetinic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased alkaline phosphatase activity] 1: Mus musculus Serum 1 gene: ALPL 1
23. 18alpha-glycyrrhetinic acid nitric oxide biosynthetic process Methotrexate 18alpha-glycyrrhetinic acid inhibits the reaction [Methotrexate results in increased nitric oxide biosynthetic process] 1: Rattus norvegicus Liver 1 gene: NOS2 1
24. 18alpha-glycyrrhetinic acid gap junction-mediated intercellular transport 18alpha-glycyrrhetinic acid results in decreased gap junction-mediated intercellular transport 1: Rattus norvegicus Liver | Cell Line   1
25. 18alpha-glycyrrhetinic acid superoxide dismutase activity Methotrexate 18alpha-glycyrrhetinic acid inhibits the reaction [Methotrexate results in decreased superoxide dismutase activity] 1: Rattus norvegicus Liver   1
26. 18alpha-glycyrrhetinic acid glutathione biosynthetic process Methotrexate 18alpha-glycyrrhetinic acid inhibits the reaction [Methotrexate results in decreased glutathione biosynthetic process] 1: Rattus norvegicus Liver 1 gene: GGT1 1
27. 18alpha-glycyrrhetinic acid lipid catabolic process Methotrexate 18alpha-glycyrrhetinic acid inhibits the reaction [Methotrexate results in increased lipid catabolic process] 1: Rattus norvegicus Liver   1
28. 18alpha-glycyrrhetinic acid alkaline phosphatase activity Methotrexate 18alpha-glycyrrhetinic acid inhibits the reaction [Methotrexate results in increased alkaline phosphatase activity] 1: Rattus norvegicus Serum 1 gene: ALPL 1
29. 18alpha-glycyrrhetinic acid L-aspartate:2-oxoglutarate aminotransferase activity Methotrexate 18alpha-glycyrrhetinic acid inhibits the reaction [Methotrexate results in increased L-aspartate:2-oxoglutarate aminotransferase activity] 1: Rattus norvegicus Serum   1
30. 18alpha-glycyrrhetinic acid L-aspartate:2-oxoglutarate aminotransferase activity 1-Naphthylisothiocyanate 18alpha-glycyrrhetinic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased L-aspartate:2-oxoglutarate aminotransferase activity] 1: Mus musculus Serum   1
31. 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid apoptotic process 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid results in increased apoptotic process 1: Homo sapiens Blood | Cell Line, Tumor 1 gene: HMOX1 1
32. 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid results in increased positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress 1: Homo sapiens Esophagus | Cell Line, Tumor   1
33. 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid apoptotic process 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid results in increased apoptotic process 1: Homo sapiens Cell Line, Tumor 1 gene: HMOX1 1
34. 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid ethyl amide positive regulation of hepatic stellate cell activation Lipopolysaccharides 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid ethyl amide inhibits the reaction [Lipopolysaccharides results in increased positive regulation of hepatic stellate cell activation] 1: Homo sapiens Liver | Hepatic Stellate Cells | Cell Line 1 gene: ACTA2 1
35. 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid ethyl amide microglial cell activation 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid ethyl amide inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased microglial cell activation] 1: Mus musculus Microglia | Cells 1 gene: TLR4 1
36. 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid ethyl amide glutathione biosynthetic process 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid ethyl amide results in increased glutathione biosynthetic process 1: Rattus norvegicus Mesencephalon | Dopaminergic Neurons | Cell Line
2 genes: GCLC | GCLM
1
37. 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid ethyl amide neuron death 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid ethyl amide inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased neuron death] 1: Mus musculus Substantia Nigra | Neurons   1
38. (2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid) trifluoroethylamide microglial cell activation 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid) trifluoroethylamide inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased microglial cell activation] 1: Mus musculus Microglia | Cells   1
39. (2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid) trifluoroethylamide glutathione biosynthetic process (2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid) trifluoroethylamide results in increased glutathione biosynthetic process 1: Rattus norvegicus Mesencephalon | Dopaminergic Neurons | Cell Line
2 genes: GCLC | GCLM
1
40. (2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid) trifluoroethylamide neuron death 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid) trifluoroethylamide inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased neuron death] 1: Mus musculus Substantia Nigra | Neurons   1
41. asiatic acid cytochrome-b5 reductase activity, acting on NAD(P)H 1,2-Dimethylhydrazine asiatic acid inhibits the reaction [1,2-Dimethylhydrazine results in increased cytochrome-b5 reductase activity, acting on NAD(P)H] 1: Rattus norvegicus Liver
2 genes: NQO1 | POR
1
42. asiatic acid cytochrome-b5 reductase activity, acting on NAD(P)H 1,2-Dimethylhydrazine asiatic acid inhibits the reaction [1,2-Dimethylhydrazine results in increased cytochrome-b5 reductase activity, acting on NAD(P)H] 1: Rattus norvegicus Colon
2 genes: NQO1 | POR
1
43. asiatic acid cell proliferation 1,2-Dimethylhydrazine asiatic acid inhibits the reaction [1,2-Dimethylhydrazine results in increased cell proliferation] 1: Rattus norvegicus Colon
3 genes: BAX | BCL2 | PCNA
1
44. asiatic acid glucuronosyltransferase activity 1,2-Dimethylhydrazine asiatic acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased glucuronosyltransferase activity] 1: Rattus norvegicus Colon   1
45. asiatic acid glucuronosyltransferase activity 1,2-Dimethylhydrazine asiatic acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased glucuronosyltransferase activity] 1: Rattus norvegicus Liver   1
46. asiatic acid glutathione transferase activity 1,2-Dimethylhydrazine asiatic acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased glutathione transferase activity] 1: Rattus norvegicus Liver   1
47. asiatic acid glutathione transferase activity 1,2-Dimethylhydrazine asiatic acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased glutathione transferase activity] 1: Rattus norvegicus Colon   1
48. Carbenoxolone apoptotic DNA fragmentation Carbenoxolone results in increased apoptotic DNA fragmentation 1: Rattus norvegicus Placenta   1
49. Carbenoxolone positive regulation of mitochondrial membrane potential Glucose | Oxygen Carbenoxolone inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased positive regulation of mitochondrial membrane potential] 1: Rattus norvegicus CA1 Region, Hippocampal | Interneurons | GABAergic Neurons 1 gene: AKT1 1
50. Carbenoxolone gap junction-mediated intercellular transport Carbenoxolone results in decreased gap junction-mediated intercellular transport 1: Rattus norvegicus Hepatocytes | Cells, Cultured   1
1–50 of 183 results.