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Chemical Growth Differentiation Factor 1

Name Growth Differentiation Factor 1
Equivalent Term GDF-1
Definition A growth differentiation factor that plays a role in the genesis of left-right asymmetry during vertebrate development. Evidence for this role is seen in MICE where loss of growth differentiation factor 1 function results in right-left isomerism of visceral organs. In HUMANS heterozygous loss of growth differentiation factor 1 function has been associated with CONGENITAL HEART DEFECTS and TRANSPOSITION OF GREAT VESSELS.
Curation Status No associations have been curated for this chemical yet.
MeSH® ID D055452
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Top ↑ Ancestors

1. ChemicalsBiological Factors Has associated genes Has associated diseases Has associated exposure references Intercellular Signaling Peptides and Proteins Has associated genes Has associated diseases TGF-beta Superfamily Proteins Growth Differentiation Factors Growth Differentiation Factor 1
2. ChemicalsBiological Factors Has associated genes Has associated diseases Has associated exposure references Intercellular Signaling Peptides and Proteins Has associated genes Has associated diseases TGF-beta Superfamily Proteins Nodal Signaling Ligands Growth Differentiation Factor 1

Top ↑ Descendants

Growth Differentiation Factor 1
  GDF1 protein, human
  Gdf1 protein, mouse
  Gdf1 protein, rat