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Chemical Heparin-binding EGF-like Growth Factor

Name Heparin-binding EGF-like Growth Factor
Equivalent Terms Diphtheria Toxin Receptor | Diphtheria Toxin Receptors | HB EGF | HB-EGF | HB EGF Precursor | HB-EGF Precursor | HB-EGF, Short Form | Heparin binding EGF like Growth Factor | Heparin-binding EGF-like Growth-Factor | Heparin binding Epidermal Growth Factor like Growth Factor Precursor Protein | Heparin-binding Epidermal Growth Factor-like Growth Factor Precursor Protein | Receptor, Diphtheria Toxin | Receptors, Diphtheria Toxin | SF HB EGF | SF HB-EGF | Short Form HB EGF | Short Form HB-EGF | Toxin Receptor, Diphtheria | Toxin Receptors, Diphtheria
Definition An EGF family member that is expressed in a variety of hematopoietic, endothelial, vascular smooth muscle, and epithelial cells. It is synthesized as a transmembrane protein which is cleaved by proteases to produce the secreted form of the protein which has specificity for the EGF RECEPTOR and the ERBB-4 RECEPTOR. The membrane-bound form of the protein has been identified as the receptor which binds to and allows DIPHTHERIA TOXIN to enter cells.
Curation Status No associations have been curated for this chemical yet.
MeSH® ID D066257
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Top ↑ Ancestors

ChemicalsBiological Factors Has associated genes Has associated diseases Has associated exposure references Intercellular Signaling Peptides and Proteins Has associated genes Has associated diseases EGF Family of Proteins Heparin-binding EGF-like Growth Factor

Top ↑ Descendants

Heparin-binding EGF-like Growth Factor
  HBEGF protein, human
  Hbegf protein, mouse
  Hbegf protein, rat