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Disease Bone Diseases, Developmental

These phenotypes are associated with Bone Diseases, Developmental or its descendants. A phenotype has an inferred association via a curated chemical interaction or a gene-GO annotation or both.

1–50 of 24,690 results.
  Phenotype Disease Chemical Inference Network Gene Inference Network References
1. apoptotic process Bone Diseases, Developmental Inferred via 14 chemicals: Angiotensin-Converting Enzyme Inhibitors | bisphenol A | Ketamine | Lead | Leflunomide | Leucovorin | Methotrexate | Phenytoin | Tetrachlorodibenzodioxin | trichostatin A | Valproic Acid | Vitamin A | Warfarin | Ziram Inferred via 3 genes: ABL1 | RPS6KA3 | TRP53 141
2. cell proliferation Bone Diseases, Developmental Inferred via 14 chemicals: 2,2',4,4',5-brominated diphenyl ether | bisphenol A | boric acid | Ketamine | Lead | Leflunomide | Methotrexate | Phenytoin | Tetrachlorodibenzodioxin | trichostatin A | Valproic Acid | Vitamin A | Warfarin | Ziram Inferred via 2 genes: DLX5 | TGFB2 157
3. cell death Bone Diseases, Developmental Inferred via 11 chemicals: bisphenol A | Ketamine | Lead | Leflunomide | Methotrexate | Phenytoin | Tetrachlorodibenzodioxin | trichostatin A | Valproic Acid | Vitamin A | Warfarin Inferred via 1 gene: TGFB2 54
4. positive regulation of cell death Bone Diseases, Developmental Inferred via 9 chemicals: 2,2',4,4',5-brominated diphenyl ether | bisphenol A | Lead | Leflunomide | Methotrexate | Phenytoin | Tetrachlorodibenzodioxin | trichostatin A | Valproic Acid   62
5. positive regulation of apoptotic process Bone Diseases, Developmental Inferred via 8 chemicals: bisphenol A | Lead | Methotrexate | Tetrachlorodibenzodioxin | trichostatin A | Valproic Acid | Warfarin | Ziram Inferred via 3 genes: ABL1 | TGFB2 | TRP53 60
6. positive regulation of cell proliferation Bone Diseases, Developmental Inferred via 8 chemicals: bisphenol A | boric acid | Ketamine | Methotrexate | Tetrachlorodibenzodioxin | trichostatin A | Valproic Acid | Warfarin Inferred via 3 genes: IGF2 | ITGB1BP1 | TGFB2 51
7. response to oxidative stress Bone Diseases, Developmental Inferred via 8 chemicals: Angiotensin-Converting Enzyme Inhibitors | bisphenol A | Ketamine | Lead | Tetrachlorodibenzodioxin | trichostatin A | Valproic Acid | Vitamin A Inferred via 2 genes: ABL1 | TRP53 56
8. cell cycle Bone Diseases, Developmental Inferred via 7 chemicals: bisphenol A | Botulinum Toxins, Type A | Leflunomide | Methotrexate | Tetrachlorodibenzodioxin | Valproic Acid | Vitamin A Inferred via 3 genes: NIPBL | RPS6KA3 | TRP53 29
9. regulation of mitochondrial membrane potential Bone Diseases, Developmental Inferred via 7 chemicals: bisphenol A | Ketamine | Phenytoin | Tetrachlorodibenzodioxin | Valproic Acid | Vitamin A | Ziram   23
10. positive regulation of reactive oxygen species biosynthetic process Bone Diseases, Developmental Inferred via 6 chemicals: bisphenol A | Lead | Methotrexate | Tetrachlorodibenzodioxin | trichostatin A | Valproic Acid   28
11. glutathione metabolic process Bone Diseases, Developmental Inferred via 6 chemicals: bisphenol A | boric acid | Lead | Methotrexate | trichostatin A | Valproic Acid   21
12. membrane lipid catabolic process Bone Diseases, Developmental Inferred via 6 chemicals: bisphenol A | Ketamine | Lead | Leucovorin | Tetrachlorodibenzodioxin | Vitamin A   45
13. regulation of blood pressure Bone Diseases, Developmental Inferred via 6 chemicals: Angiotensin-Converting Enzyme Inhibitors | Ketamine | Lead | Tetrachlorodibenzodioxin | Valproic Acid | Warfarin   70
14. cell differentiation Bone Diseases, Developmental Inferred via 5 chemicals: bisphenol A | Tetrachlorodibenzodioxin | trichostatin A | Valproic Acid | Vitamin A Inferred via 4 genes: BMPR1B | ITGB1BP1 | SH3PXD2B | ZIC3 27
15. cell migration Bone Diseases, Developmental Inferred via 5 chemicals: bisphenol A | Phenytoin | Tetrachlorodibenzodioxin | trichostatin A | Valproic Acid Inferred via 2 genes: ITGB1BP1 | TGFB2 26
16. mitotic cell cycle arrest Bone Diseases, Developmental Inferred via 5 chemicals: bisphenol A | Methotrexate | Tetrachlorodibenzodioxin | trichostatin A | Valproic Acid Inferred via 1 gene: TRP53 17
17. glutathione peroxidase activity Bone Diseases, Developmental Inferred via 5 chemicals: 2,2',4,4',5-brominated diphenyl ether | bisphenol A | Lead | Methotrexate | Tetrachlorodibenzodioxin   18
18. cell death Hypertelorism Inferred via 5 chemicals: Carbamazepine | Methotrexate | Phenobarbital | Phenytoin | Valproic Acid   20
19. superoxide dismutase activity Bone Diseases, Developmental Inferred via 5 chemicals: 2,2',4,4',5-brominated diphenyl ether | bisphenol A | Ethylene Glycol | Lead | Methotrexate   21
20. glutathione biosynthetic process Bone Diseases, Developmental Inferred via 5 chemicals: bisphenol A | Lead | Methotrexate | Phenytoin | Tetrachlorodibenzodioxin   27
21. alkaline phosphatase activity Bone Diseases, Developmental Inferred via 5 chemicals: bisphenol A | Lead | Methotrexate | Tetrachlorodibenzodioxin | Warfarin   14
22. reactive oxygen species biosynthetic process Bone Diseases, Developmental Inferred via 5 chemicals: bisphenol A | Leflunomide | Tetrachlorodibenzodioxin | Valproic Acid | Ziram   26
23. positive regulation of cell death Hypertelorism Inferred via 5 chemicals: Carbamazepine | Methotrexate | Phenobarbital | Phenytoin | Valproic Acid   40
24. negative regulation of cell proliferation Bone Diseases, Developmental Inferred via 4 chemicals: bisphenol A | Tetrachlorodibenzodioxin | trichostatin A | Valproic Acid Inferred via 4 genes: ITGB1BP1 | NPPC | TGFB2 | TRP53 31
25. cell proliferation Osteochondrodysplasias Inferred via 4 chemicals: Disulfiram | Lidocaine | Manganese | Ziram Inferred via 2 genes: BCL2 | VEGFA 21
26. apoptotic process Osteochondrodysplasias Inferred via 4 chemicals: Disulfiram | Lidocaine | Manganese | Ziram Inferred via 1 gene: BCL2 26
27. response to oxidative stress Osteochondrodysplasias Inferred via 4 chemicals: Disulfiram | Lidocaine | Manganese | Thiram Inferred via 1 gene: BCL2 12
28. neuron differentiation Bone Diseases, Developmental Inferred via 4 chemicals: 2,2',4,4',5-brominated diphenyl ether | bisphenol A | Lead | Valproic Acid Inferred via 1 gene: ABL1 12
29. regulation of mitochondrial membrane potential Osteochondrodysplasias Inferred via 4 chemicals: Disulfiram | Lidocaine | Manganese | Ziram Inferred via 1 gene: BCL2 11
30. drug metabolic process Hypertelorism Inferred via 4 chemicals: Carbamazepine | Phenobarbital | Phenytoin | Valproic Acid   8
31. lipid catabolic process Bone Diseases, Developmental Inferred via 4 chemicals: bisphenol A | Ethylene Glycol | Methotrexate | Warfarin   22
32. glucose homeostasis Bone Diseases, Developmental Inferred via 4 chemicals: bisphenol A | boric acid | Lead | Tetrachlorodibenzodioxin   15
33. glutathione transferase activity Bone Diseases, Developmental Inferred via 4 chemicals: 2,2',4,4',5-brominated diphenyl ether | bisphenol A | Tetrachlorodibenzodioxin | Vitamin A   19
34. spermatogenesis Bone Diseases, Developmental Inferred via 4 chemicals: bisphenol A | boric acid | Tetrachlorodibenzodioxin | Vitamin A   19
35. apoptotic process Hypertelorism Inferred via 4 chemicals: Methotrexate | Phenobarbital | Phenytoin | Valproic Acid   30
36. cell proliferation Hypertelorism Inferred via 4 chemicals: Methotrexate | Phenobarbital | Phenytoin | Valproic Acid   34
37. drug metabolic process Bone Diseases, Developmental Inferred via 4 chemicals: Ketamine | Phenytoin | Valproic Acid | Warfarin   9
38. detection of oxidative stress Hypertelorism Inferred via 4 chemicals: Carbamazepine | Phenobarbital | Phenytoin | Valproic Acid   8
39. membrane lipid catabolic process Osteochondrodysplasias Inferred via 4 chemicals: Disulfiram | Lidocaine | Manganese | Mexiletine   10
40. DNA methylation Bone Diseases, Developmental Inferred via 4 chemicals: bisphenol A | Lead | Tetrachlorodibenzodioxin | Valproic Acid   19
41. positive regulation of superoxide dismutase activity Bone Diseases, Developmental Inferred via 4 chemicals: 2,2',4,4',5-brominated diphenyl ether | bisphenol A | boric acid | Methotrexate   17
42. wound healing, spreading of cells Bone Diseases, Developmental Inferred via 4 chemicals: 2,2',4,4',5-brominated diphenyl ether | bisphenol A | boric acid | trichostatin A   11
43. positive regulation of protein import into nucleus Bone Diseases, Developmental Inferred via 4 chemicals: bisphenol A | boric acid | Methotrexate | Valproic Acid   15
44. positive regulation of histone H3-K9 acetylation Bone Diseases, Developmental Inferred via 4 chemicals: bisphenol A | Lead | trichostatin A | Valproic Acid   9
45. protein oxidation Bone Diseases, Developmental Inferred via 4 chemicals: bisphenol A | Lead | Methotrexate | Ziram   11
46. cell growth Bone Diseases, Developmental Inferred via 4 chemicals: bisphenol A | Methotrexate | trichostatin A | Valproic Acid   15
47. positive regulation of mitochondrial membrane potential Bone Diseases, Developmental Inferred via 4 chemicals: bisphenol A | Lead | Tetrachlorodibenzodioxin | Valproic Acid   13
48. detection of oxidative stress Bone Diseases, Developmental Inferred via 4 chemicals: bisphenol A | Lead | Phenytoin | Valproic Acid   10
49. regulation of blood pressure Osteochondrodysplasias Inferred via 4 chemicals: Disulfiram | Lidocaine | Manganese | Mexiletine   18
50. testosterone biosynthetic process Bone Diseases, Developmental Inferred via 4 chemicals: bisphenol A | Ketamine | Tetrachlorodibenzodioxin | Ziram   25
1–50 of 24,690 results.