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Disease Bone Diseases, Developmental

These phenotypes are associated with Bone Diseases, Developmental or its descendants. A phenotype has an inferred association via a curated chemical interaction or a gene-GO annotation or both.

1–50 of 24,246 results.
  Phenotype Disease Chemical Inference Network Gene Inference Network References
1. apoptotic process Bone Diseases, Developmental Inferred via 12 chemicals: Angiotensin-Converting Enzyme Inhibitors | Ketamine | Lead | Leflunomide | Leucovorin | Methotrexate | Phenytoin | Tetrachlorodibenzodioxin | trichostatin A | Valproic Acid | Vitamin A | Warfarin Inferred via 3 genes: ABL1 | RPS6KA3 | TRP53 104
2. cell proliferation Bone Diseases, Developmental Inferred via 12 chemicals: 2,2',4,4',5-brominated diphenyl ether | boric acid | Ketamine | Lead | Leflunomide | Methotrexate | Phenytoin | Tetrachlorodibenzodioxin | trichostatin A | Valproic Acid | Vitamin A | Warfarin Inferred via 2 genes: DLX5 | TGFB2 77
3. cell death Bone Diseases, Developmental Inferred via 10 chemicals: Ketamine | Lead | Leflunomide | Methotrexate | Phenytoin | Tetrachlorodibenzodioxin | trichostatin A | Valproic Acid | Vitamin A | Warfarin Inferred via 1 gene: TGFB2 46
4. positive regulation of cell death Bone Diseases, Developmental Inferred via 8 chemicals: 2,2',4,4',5-brominated diphenyl ether | Lead | Leflunomide | Methotrexate | Phenytoin | Tetrachlorodibenzodioxin | trichostatin A | Valproic Acid   51
5. positive regulation of cell proliferation Bone Diseases, Developmental Inferred via 7 chemicals: boric acid | Ketamine | Methotrexate | Tetrachlorodibenzodioxin | trichostatin A | Valproic Acid | Warfarin Inferred via 3 genes: IGF2 | ITGB1BP1 | TGFB2 26
6. positive regulation of apoptotic process Bone Diseases, Developmental Inferred via 7 chemicals: Lead | Methotrexate | Tetrachlorodibenzodioxin | trichostatin A | Valproic Acid | Warfarin | Ziram Inferred via 3 genes: ABL1 | TGFB2 | TRP53 44
7. response to oxidative stress Bone Diseases, Developmental Inferred via 7 chemicals: Angiotensin-Converting Enzyme Inhibitors | Ketamine | Lead | Tetrachlorodibenzodioxin | trichostatin A | Valproic Acid | Vitamin A Inferred via 2 genes: ABL1 | TRP53 53
8. cell cycle Bone Diseases, Developmental Inferred via 6 chemicals: Botulinum Toxins, Type A | Leflunomide | Methotrexate | Tetrachlorodibenzodioxin | Valproic Acid | Vitamin A Inferred via 3 genes: NIPBL | RPS6KA3 | TRP53 26
9. regulation of blood pressure Bone Diseases, Developmental Inferred via 6 chemicals: Angiotensin-Converting Enzyme Inhibitors | Ketamine | Lead | Tetrachlorodibenzodioxin | Valproic Acid | Warfarin   70
10. cell death Hypertelorism Inferred via 5 chemicals: Carbamazepine | Methotrexate | Phenobarbital | Phenytoin | Valproic Acid   20
11. regulation of mitochondrial membrane potential Bone Diseases, Developmental Inferred via 5 chemicals: Ketamine | Phenytoin | Tetrachlorodibenzodioxin | Valproic Acid | Vitamin A   15
12. positive regulation of cell death Hypertelorism Inferred via 5 chemicals: Carbamazepine | Methotrexate | Phenobarbital | Phenytoin | Valproic Acid   40
13. glutathione metabolic process Bone Diseases, Developmental Inferred via 5 chemicals: boric acid | Lead | Methotrexate | trichostatin A | Valproic Acid   14
14. membrane lipid catabolic process Bone Diseases, Developmental Inferred via 5 chemicals: Ketamine | Lead | Leucovorin | Tetrachlorodibenzodioxin | Vitamin A   43
15. positive regulation of reactive oxygen species biosynthetic process Bone Diseases, Developmental Inferred via 5 chemicals: Lead | Methotrexate | Tetrachlorodibenzodioxin | trichostatin A | Valproic Acid   15
16. cell differentiation Bone Diseases, Developmental Inferred via 4 chemicals: Tetrachlorodibenzodioxin | trichostatin A | Valproic Acid | Vitamin A Inferred via 4 genes: BMPR1B | ITGB1BP1 | SH3PXD2B | ZIC3 25
17. cell migration Bone Diseases, Developmental Inferred via 4 chemicals: Phenytoin | Tetrachlorodibenzodioxin | trichostatin A | Valproic Acid Inferred via 2 genes: ITGB1BP1 | TGFB2 12
18. response to oxidative stress Osteochondrodysplasias Inferred via 4 chemicals: Disulfiram | Lidocaine | Manganese | Thiram Inferred via 1 gene: BCL2 12
19. mitotic cell cycle arrest Bone Diseases, Developmental Inferred via 4 chemicals: Methotrexate | Tetrachlorodibenzodioxin | trichostatin A | Valproic Acid Inferred via 1 gene: TRP53 14
20. drug metabolic process Hypertelorism Inferred via 4 chemicals: Carbamazepine | Phenobarbital | Phenytoin | Valproic Acid   8
21. cell proliferation Hypertelorism Inferred via 4 chemicals: Methotrexate | Phenobarbital | Phenytoin | Valproic Acid   34
22. detection of oxidative stress Hypertelorism Inferred via 4 chemicals: Carbamazepine | Phenobarbital | Phenytoin | Valproic Acid   8
23. superoxide dismutase activity Bone Diseases, Developmental Inferred via 4 chemicals: 2,2',4,4',5-brominated diphenyl ether | Ethylene Glycol | Lead | Methotrexate   10
24. membrane lipid catabolic process Osteochondrodysplasias Inferred via 4 chemicals: Disulfiram | Lidocaine | Manganese | Mexiletine   10
25. glutathione peroxidase activity Bone Diseases, Developmental Inferred via 4 chemicals: 2,2',4,4',5-brominated diphenyl ether | Lead | Methotrexate | Tetrachlorodibenzodioxin   10
26. drug metabolic process Bone Diseases, Developmental Inferred via 4 chemicals: Ketamine | Phenytoin | Valproic Acid | Warfarin   9
27. regulation of blood pressure Osteochondrodysplasias Inferred via 4 chemicals: Disulfiram | Lidocaine | Manganese | Mexiletine   18
28. apoptotic process Hypertelorism Inferred via 4 chemicals: Methotrexate | Phenobarbital | Phenytoin | Valproic Acid   30
29. regulation of heart rate Bone Diseases, Developmental Inferred via 4 chemicals: Angiotensin-Converting Enzyme Inhibitors | Ketamine | Lead | Tetrachlorodibenzodioxin   23
30. apoptotic DNA fragmentation Bone Diseases, Developmental Inferred via 4 chemicals: Ketamine | Tetrachlorodibenzodioxin | Valproic Acid | Vitamin A   19
31. glutathione biosynthetic process Bone Diseases, Developmental Inferred via 4 chemicals: Lead | Methotrexate | Phenytoin | Tetrachlorodibenzodioxin   11
32. alkaline phosphatase activity Bone Diseases, Developmental Inferred via 4 chemicals: Lead | Methotrexate | Tetrachlorodibenzodioxin | Warfarin   10
33. negative regulation of cell proliferation Bone Diseases, Developmental Inferred via 3 chemicals: Tetrachlorodibenzodioxin | trichostatin A | Valproic Acid Inferred via 4 genes: ITGB1BP1 | NPPC | TGFB2 | TRP53 14
34. cell proliferation Osteochondrodysplasias Inferred via 3 chemicals: Disulfiram | Lidocaine | Manganese Inferred via 2 genes: BCL2 | VEGFA 20
35. apoptotic process Osteochondrodysplasias Inferred via 3 chemicals: Disulfiram | Lidocaine | Manganese Inferred via 1 gene: BCL2 25
36. cell growth Bone Diseases, Developmental Inferred via 3 chemicals: Methotrexate | trichostatin A | Valproic Acid Inferred via 1 gene: TGFB2 10
37. regulation of mitochondrial membrane potential Osteochondrodysplasias Inferred via 3 chemicals: Disulfiram | Lidocaine | Manganese Inferred via 1 gene: BCL2 10
38. apoptotic process Craniosynostoses Inferred via 3 chemicals: Cyclophosphamide | Phenytoin | Valproic Acid Inferred via 1 gene: FGFR2 37
39. neuron differentiation Bone Diseases, Developmental Inferred via 3 chemicals: 2,2',4,4',5-brominated diphenyl ether | Lead | Valproic Acid Inferred via 1 gene: ABL1 9
40. apoptotic process Marfan Syndrome Inferred via 3 chemicals: Atenolol | Doxycycline | Losartan Inferred via 1 gene: TGFBR2 22
41. positive regulation of reactive oxygen species biosynthetic process Osteochondrodysplasias Inferred via 3 chemicals: Disulfiram | Manganese | Thiram   11
42. alkaline phosphatase activity Dysostoses Inferred via 3 chemicals: Ethanol | Tetrachlorodibenzodioxin | Warfarin   11
43. positive regulation of apoptotic process Hypertelorism Inferred via 3 chemicals: Carbamazepine | Methotrexate | Valproic Acid   24
44. regulation of mitochondrial membrane potential Hypertelorism Inferred via 3 chemicals: Phenobarbital | Phenytoin | Valproic Acid   9
45. cell growth Hypertelorism Inferred via 3 chemicals: Carbamazepine | Methotrexate | Valproic Acid   9
46. positive regulation of protein import into nucleus Hypertelorism Inferred via 3 chemicals: Methotrexate | Phenobarbital | Valproic Acid   7
47. apoptotic process Dysostoses Inferred via 3 chemicals: Ethanol | Tetrachlorodibenzodioxin | Warfarin   63
48. DNA damage response, detection of DNA damage Hypertelorism Inferred via 3 chemicals: Phenobarbital | Phenytoin | Valproic Acid   9
49. positive regulation of cell proliferation Hypertelorism Inferred via 3 chemicals: Methotrexate | Phenobarbital | Valproic Acid   11
50. positive regulation of apoptotic process Osteochondrodysplasias Inferred via 3 chemicals: Disulfiram | Manganese | Ziram   8
1–50 of 24,246 results.