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Disease Calcium Metabolism Disorders

These are exposure studies associated with the disease and all of its children.

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  Reference Associated Study Title Author's Summary Study Factors Stressor Receptors Country Medium Exposure Marker Measurements Outcome
1. Kukkonen MK, et al. (2014). Our results support the hypothesis that the inflammasome is important in the development of fibrotic lung disease by associating the NLRP3 rs35829419 variant allele with increased risk of asbestos-related interstitial lung fibrosis, and the TGFB1 rs2241718 variant allele with decreased risk of asbestos-related visceral pleural fibrosis; polymorphisms in CARD8 and TIMP2 are proposed to modify the development and/or calcification of pleural thickenings. genetics Asbestos Subjects with gene influence:CARD8 | Subjects with gene influence:NLRP3 | Subjects with gene influence:TGFB1 | Subjects with gene influence:TIMP2 | Workers Finland Details Asbestosis | Calcinosis | Fibrosis | Occupational Diseases | Pleural Diseases