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Disease Cardiovascular Diseases

These are exposure studies associated with the disease and all of its children.

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1–50 of 151 results.
  Reference Associated Study Title Author's Summary Study Factors Stressor Receptors Country Medium Exposure Marker Measurements Outcome
1. Goncharov A, et al. (2008). High serum polychlorinated biphenyls are associated with elevation of serum lipids and cardiovascular disease in a Native American population. age 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5-pentachlorobiphenyl | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,4',5-tetrachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,4,5,2',5'-pentachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | Hexachlorobenzene | Mirex | PCB 180 | Polychlorinated Biphenyls Study subjects Canada|United States serum 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5-pentachlorobiphenyl | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,4',5-tetrachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,4,5,2',5'-pentachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | Hexachlorobenzene | Mirex | PCB 180 | Polychlorinated Biphenyls Details Cardiovascular Diseases | cholesterol biosynthetic process | triglyceride biosynthetic process
2. Godduhn A, et al. (2013). Northway Health Study (NHS) The NHS found complex patterns of association between reported resource uses and cancer and thyroid-, reproductive-, metabolic-, and cardiac problems. 2,4,5-Trichlorophenoxyacetic Acid | Chlorine | Pesticides | Petroleum | Vehicle Emissions Study subjects United States Details Cardiovascular Diseases | Neoplasms | Thyroid Diseases | Urologic Diseases
3. Schreinemachers DM. (2010). National Health and Nutrition Examination Survey (NHANES) The results indicate that exposure to 2,4-dichlorophenoxyacetic acid was associated with changes in biomarkers that, based on the published literature, have been linked to risk factors for acute myocardial infarction and type 2 diabetes. 2,4-Dichlorophenoxyacetic Acid Study subjects United States urine 2,4-Dichlorophenoxyacetic Acid Details Diabetes Mellitus, Type 2 | Heart Diseases | cellular triglyceride homeostasis | glucose metabolic process | insulin metabolic process | thyroid-stimulating hormone secretion
4. DeJarnett N, et al. (2014). Louisville Healthy Heart Study Regardless of its source, acrolein exposure is associated with platelet activation and suppression of circulating angiogenic cell levels, as well as increased cardiovascular disease risk. Acrolein Study subjects United States urine S-(3-hydroxypropyl)cysteine N-acetate Details Cardiovascular Diseases | blood vessel endothelial cell migration | platelet activation
5. Künzli N, et al. (2010). B-Vitamin Atherosclerosis Intervention Trial (BVAIT) | Estrogen in the Prevention of Atherosclerosis Trial (EPAT) | Troglitazone Atherosclerosis Regression Trial (TART) | Vitamin E Atherosclerosis Prevention Study (VEAPS) | Women's Estrogen-Progestin Lipid-Lowering Hormone Atherosclerosis Regression Trial (WELL-HART) Consistent with cross-sectional findings and animal studies, this is the first study to report an association between exposure to air pollution and the progression of atherosclerosis - indicated with carotid artery intima-media thickness change - in humans. Air Pollutants Study subjects United States air Particulate Matter Details Atherosclerosis
6. Symons JM, et al. (2006). The authors evaluated the association between particulate matter PM2.5 exposure and onset of congestive heart failure symptom exacerbation leading to hospital admission; although overall findings were not statistically significant, the identification of case events defined by an 8-hour onset period may be more relevant than either a 24-hour onset period or the admission date for estimating harmful effects. Air Pollutants Subjects with disease:Heart Failure United States air, ambient Carbon Monoxide | Nitrogen Dioxide | Ozone | Particulate Matter Details
7. Jung CR, et al. (2017). Our results provide new evidence that exposure to ozone may increase the risk of Kawasaki disease in children. Air Pollutants Children | Subjects with disease:Mucocutaneous Lymph Node Syndrome Taiwan, Province of China air, ambient Carbon Monoxide | Nitrogen Dioxide | Ozone | Particulate Matter | Sulfur Dioxide Details Mucocutaneous Lymph Node Syndrome
8. Dehbi HM, et al. (2017). National Survey of Health and Development (NSHD) | Southall And Brent Revisited (SABRE) Study We examined associations between air pollution and cardiovascular disease mortality in two British cohorts with over 25 years of follow-up; our results support a detrimental long-term effect for air pollutants on cardiovascular mortality. Air Pollutants Study subjects United Kingdom air, ambient Nitrogen Dioxide | Nitrogen Oxides | Particulate Matter | Smoke | Sulfur Dioxide Details Cardiovascular Diseases | Death
9. López-Villarrubia E, et al. (2010). Our findings indicate the existence of a short-term association between current exposure levels to air pollutants and total mortality as well as mortality due to heart and respiratory diseases in both Canary cities studied along with evidence that the association on a given day may spread over several successive days. Air Pollutants Spain air Carbon Monoxide | Nitrogen Dioxide | Ozone | Particulate Matter | Sulfur Dioxide Details Death | Heart Diseases | Respiratory Tract Diseases
10. Jones MR, et al. (2015). Multi-Ethnic Study of Atherosclerosis (MESA) The smaller carotid intima-media thickness levels in U.S. Chinese participants were even smaller after accounting for higher particulate matter (PM2.5) concentrations compared with Caucasian-Americans; however, air pollution was not related to intima-media thickness differences in African-Americans and Hispanics compared with Caucasian-Americans. race Air Pollutants Study subjects United States air, ambient Nitrogen Oxides | Particulate Matter Details Carotid Intimal Medial Thickness 1 | blood vessel development
11. Zhang F, et al. (2011). Study on the association between ambient air pollution and daily cardiovascular and respiratory mortality in an urban district of Beijing. Air Pollutants Study subjects China air, ambient Nitrogen Dioxide | Particulate Matter | Sulfur Dioxide Details Cardiovascular Diseases | Death | Respiratory Tract Diseases
12. Medina-Ramón M, et al. (2008). Worcester Heart Attack Study Residential exposure to traffic-related air pollution increases the mortality risk after hospitalization with acute heart failure. Air Pollutants Subjects with disease:Heart Failure United States Details Death
13. Andersen ZJ, et al. (2012). Danish Diet, Cancer, and Health cohort Study Long-term exposure to traffic-related air pollution may contribute to the development of ischemic but not hemorrhagic stroke, especially severe ischemic strokes leading to death within 30 days. Air Pollutants Study subjects Denmark Nitrogen Dioxide Details Brain Ischemia | Cerebral Hemorrhage | Stroke
14. Pun VC, et al. (2015). Nurses' Health Study (NHS) Particulate matter in the prior 1 and 12 months is associated with pulmonary embolism risk, and women with underlying health conditions may be more susceptible to pulmonary embolism after particulate matter exposure. sex Air Pollutants Study subjects United States air, ambient Particulate Matter Details Pulmonary Embolism
15. Hansen AB, et al. (2016). Danish Nurse Cohort We examined the association between long-term exposure to particulate matter (PM2.5) and diabetes incidence; non-smokers, obese subjects, and cardiovascular disease patients may be most susceptible to development of diabetes related to air pollution. disease | tobacco Air Pollutants Subjects with disease:Diabetes Mellitus | Subjects with disease:Myocardial Infarction | Subjects with disease:Obesity | Study subjects Denmark air, ambient Nitrogen Dioxide | Nitrogen Oxides | Particulate Matter Details Diabetes Mellitus
16. Kan H, et al. (2007). Global Air Quality Guidelines set by World Health Organization | US National Ambient Air Quality Standards Our analyses provide the first statistically significant evidence in China that particulate matter (PM2.5) has an adverse effect on population health and strengthen the rationale for further limiting levels of PM2.5 in outdoor air in Shanghai. Air Pollutants Study subjects China|United States air, ambient Ozone | Particulate Matter Details Cardiovascular Diseases | Respiratory Tract Diseases
17. Zhang P, et al. (2011). Long-term exposure to ambient air pollution is associated with the death of cardiovascular and cerebrovascular diseases among Chinese populations. The effects of air pollution were more evident in female that in male, and nonsmokers and residents with body mass index less than 18.5 were more vulnerable to outdoor air pollution. body mass index | sex | tobacco Air Pollutants Study subjects China air, ambient Nitrogen Dioxide | Particulate Matter | Sulfur Dioxide Details Cardiovascular Diseases | Cerebrovascular Disorders | Death
18. Brüske I, et al. (2011). Air Pollution and Inflammatory Response in Myocardial Infarction Survivors: Gene-Environment Interaction in a High Risk Group (AIRGENE) These preliminary findings should be replicated in other study populations because they suggest that the accumulation of acute and subacute effects or the chronic exposure to ambient particulate and gaseous air pollution may result in the promotion of atherosclerosis, mediated, at least in part, by increased levels of lipoprotein-associated phospholipase A2. Air Pollutants | Carbon Monoxide | Nitric Oxide | Nitrogen Dioxide | Ozone | Particulate Matter | Sulfur Dioxide Subjects with disease:Myocardial Infarction Germany air, ambient | plasma Carbon Monoxide | Nitric Oxide | Nitrogen Dioxide | Ozone | Particulate Matter | PLA2G7 | Sulfur Dioxide Details Atherosclerosis
19. Fung KY, et al. (2007). Since hospital admissions rates were significantly higher in 'Chemical Valley' as compared to both London and Windsor, we hypothesize that these higher rates are pollution related. Air Pollutants | Carbon Monoxide | Nitrogen Dioxide | Ozone | Sulfur Dioxide Canada air Carbon Monoxide | Nitrogen Dioxide | Ozone | Sulfur Dioxide Details Cardiovascular Diseases | Respiratory Tract Diseases
20. Ljungman P, et al. (2009). Air Pollution and Inflammatory Response in Myocardial Infarction Survivors: Gene-Environment Interaction in a High Risk Group (AIRGENE) We found the interleukin-6 response to air pollution is modified by genetic polymorphisms in IL6 and FGB genes, suggesting the effect of gaseous traffic-related air pollution on inflammation may be stronger in genetic subpopulations with ischemic heart disease. disease | genetics Air Pollutants | Carbon Monoxide | Vehicle Emissions Subjects with gene influence:FGB | Subjects with gene influence:IL6 | Subjects with disease:Myocardial Infarction Finland|Germany|
Greece|Italy|
Spain|Sweden
air, ambient | plasma Carbon Monoxide | IL6 | Nitrogen Dioxide | Particulate Matter Details positive regulation of interleukin-6 production
21. Delfino RJ, et al. (2010). Traffic emission sources of organic chemicals represented by polycyclic aromatic hydrocarbons are associated with increased systemic inflammation and explain associations with quasi-ultrafine particle mass. Air Pollutants | hopane | Polycyclic Aromatic Hydrocarbons | Vehicle Emissions Subjects with disease:Coronary Artery Disease United States air, outdoor | plasma Alkanes | Chromium | Copper | hopane | IL6 | Iron | Manganese | Nickel | Particulate Matter | Polycyclic Aromatic Hydrocarbons | TNFRSF1B | Vanadium | Zinc Details
22. Levinsson A, et al. (2014). INTERGENE/ADONIX Air pollution exposure entails an increased risk of acute myocardial infarction, and this risk differed over genotype strata for variants in the GSTP1, GSTT1 and GSTCD genes, albeit not statistically-significantly. genetics Air Pollutants | Nitrogen Dioxide Subjects with gene influence:GSTP1 | Controls for disease:Myocardial Infarction | Subjects with disease:Myocardial Infarction Sweden Nitrogen Dioxide Details Hypertension | Myocardial Infarction
23. Zúñiga J, et al. (2016). There could be an association between the air pollution in Panama City (Panama) and an increase in cardiovascular and respiratory mortality. Air Pollutants | Nitrogen Dioxide | Ozone | Particulate Matter Study subjects Panama air, ambient Nitrogen Dioxide | Ozone | Particulate Matter Details Cardiovascular Diseases | Death | Respiratory Tract Diseases
24. Hankey S, et al. (2012). Between-neighborhood differences in estimated ischemic heart disease mortality from air pollution were comparable in magnitude, suggesting that population health benefits from increased physical activity in high-walkability neighborhoods may be offset by adverse effects of air pollution exposure. physical activity Air Pollutants | Nitrogen Oxides | Ozone | Particulate Matter Study subjects United States air Nitrogen Dioxide | Nitrogen Oxides | Ozone | Particulate Matter Details Myocardial Ischemia
25. Liu CB, et al. (2016). Our findings suggest some positive associations between maternal exposure to ambient particulate matter (PM10) during the first two months of pregnancy and fetal cardiovascular malformations. Air Pollutants | Particulate Matter Infants or newborns | Pregnant females China air, ambient Particulate Matter Details Cardiovascular Abnormalities | Ductus Arteriosus, Patent | Heart Septal Defects, Atrial | Heart Septal Defects, Ventricular | Tetralogy of Fallot
26. Cao J, et al. (2012). Our findings suggest that Particulate Matter (PM2.5) constituents from the combustion of fossil fuel may have an appreciable influence on the health effects attributable to PM2.5 in Xi'an. Air Pollutants | Particulate Matter China air Arsenic | Bromine | Cadmium | Calcium | Chlorides | Chlorine | Chromium | Fluorides | Iron | Lead | Magnesium | Manganese | Molybdenum | Nickel | Nitrates | Nitrites | Nitrogen Dioxide | Particulate Matter | Potassium | Sodium | Sulfates | Sulfur | Sulfur Dioxide | Titanium | Zinc Details Cardiovascular Diseases | Respiration Disorders
27. Pope CA 3RD, et al. (2011). American Cancer Society Cancer Prevention Study II (ACS CPS-II) The exposure-response relationship associated with PM2.5 is qualitatively different for lung cancer versus cardiovascular mortality. At low exposure levels, cardiovascular deaths are projected to account for most of the burden of disease, whereas at high levels of PM2.5, lung cancer becomes proportionately more important. tobacco Air Pollutants | Particulate Matter Study subjects United States cigarette Particulate Matter Details Cardiovascular Diseases | Death | Lung Neoplasms
28. Goodman PG, et al. (2004). We assessed the associations of particulate pollution (black smoke) and temperature with age-standardized daily mortality rates over 17 years in Dublin, Ireland, using a polynomial distributed lag model of both temperature and particulate air pollution simultaneously through 40 days after exposure. Air Pollutants | Particulate Matter | Smoke Study subjects Ireland air Smoke Details Cardiovascular Diseases | Death | Respiratory Tract Diseases
29. Samoli E, et al. (2016). Our results suggest that exhaust-related pollutants are associated with increased numbers of adult cardiovascular and pediatric respiratory hospitalizations. age Air Pollutants | Particulate Matter | Vehicle Emissions Children | Study subjects United Kingdom air, ambient Aluminum | Carbon | Carbon Monoxide | Copper | Nitrogen Dioxide | Nitrogen Oxides | Ozone | Particulate Matter | Soot | Sulfur Dioxide | Zinc Details Cardiovascular Diseases | Respiratory Tract Diseases
30. Ward-Caviness CK, et al. (2016). CATHeterization GENetics (CATHGEN) Our results reveal a novel gene (and possibly gene family) associated with peripheral arterial disease, via an interaction with traffic air pollution exposure; these results highlight the potential for interactions studies, particularly at the genome scale, to reveal novel biology linking environmental exposures to clinical outcomes. genetics Air Pollutants | Vehicle Emissions Subjects with gene influence:BMP2 | Subjects with gene influence:BMP8A United States Details Peripheral Arterial Disease
31. Monrad M, et al. (2017). Danish Diet, Cancer, and Health cohort Study We found long-term residential traffic-related air pollution to be associated with higher risk of atrial fibrillation. Air Pollutants | Vehicle Emissions Study subjects Denmark air, ambient Nitrogen Dioxide | Nitrogen Oxides Details Atrial Fibrillation
32. Zhang W, et al. (1994). We report early health effects and biological monitoring in persons occupationally exposed to tetraethyl lead in China for the years 1990-1992, including for gasoline depot workers and traffic police officers. Air Pollutants, Occupational | Tetraethyl Lead Workers China air, ambient | urine diethyllead | Lead | triethyllead Details Bradycardia | Tremor
33. Lee WJ, et al. (2004). Agricultural Health Study (AHS) Our findings suggest a possible association between alachlor application and incidence of lymphohematopoietic cancers among applicators in the Agricultural Health Study. alachlor Workers United States Details Agricultural Workers' Diseases | Hematologic Neoplasms | Leukemia | Multiple Myeloma
34. Zhou J, et al. (2011). The Particulate Matter (PM2.5) components and gaseous pollutants associated with mortality in Detroit were most associated with warm season secondary aerosols and traffic markers. In Seattle, the component species most closely associated with mortality included those for cold season traffic and other combustion sources, such as residual oil and wood burning. Aluminum | Carbon | Carbon Dioxide | Iron | Nickel | Nitrogen Dioxide | Ozone | Particulate Matter | Potassium | Silicon | Sodium | Sulfur | Vanadium | Zinc United States air Aluminum | Carbon | Carbon Dioxide | Iron | Nickel | Nitrogen Dioxide | Ozone | Particulate Matter | Potassium | Silicon | Sodium | Sulfur | Vanadium | Zinc Details Cardiovascular Diseases | Respiratory Tract Diseases
35. Stamp LK, et al. (2015). We have replicated findings identifying dust exposure (grain and silica) and farm exposure as risk factors for granulomatosis with polyangiitis; we have shown activities associated with exposure to inhaled antigens (in particular those related to farming or gardening) may increase the risk of the disease. Antigens | Dust | Silicon Dioxide Controls for disease:Granulomatosis with Polyangiitis | Subjects with disease:Granulomatosis with Polyangiitis New Zealand Details Granulomatosis with Polyangiitis
36. Chen Y, et al. (2007). Health Effects of Arsenic Longitudinal Study (HEALS) The findings indicate an effect of chronic arsenic exposure from drinking water on vascular inflammation that persists over time and also suggest a potential mechanism underlying the association between arsenic exposure and cardiovascular disease. Arsenic Subjects with disease:Skin Ulcer Bangladesh plasma | urine | water Arsenic | ICAM1 | VCAM1 Details Cardiovascular Diseases | gene expression
37. Yuan Y, et al. (2007). We conclude that the major impact of arsenic in drinking water on circulatory disease involves acute myocardial infarction and that, in the initial years, it is the main cause of death from arsenic in drinking water, superseded in later years by excess mortality from lung and bladder cancer. Arsenic Study subjects Chile water Arsenic Details Lung Neoplasms | Myocardial Infarction | Urinary Bladder Neoplasms
38. Mumford JL, et al. (2007). We found significant association between chronic arsenic exposure and QT interval prolongation in a human population. sex Arsenic Study subjects China nail Arsenic Details Cardiovascular Abnormalities | regulation of heart contraction
39. Pi J, et al. (2005). A 13-month arsenic exposure reduction effectively reverses the arsenic-induced impairment of the nitric oxide/cyclic guanosine 3',5'-monophosphate pathway in both males and females and improves peripheral vascular function in males. Arsenic Study subjects China blood | urine | water Arsenic | Cyclic GMP Details Arsenic Poisoning | Vascular Diseases
40. Wade TJ, et al. (2009). This is the first study to document increased arsenic-associated mortality in the Bayingnormen Inner Mongolia region of China. Arsenic Study subjects China water Arsenic Details Coronary Disease | Death | Neoplasms
41. Xia Y, et al. (2009). We conducted a census of one arsenic-exposed village in the Ba Men region, Shahai village located in Hangjin Hou county with the goal of documenting arsenic exposures in the region, recording the prevalence of arsenic induced skin lesions, and describing the demographic factors associated with arsenic exposures, and arsenic toxicity. Arsenic Study subjects China water Arsenic Details Cardiovascular Diseases | Skin Ulcer
42. Cui N, et al. (2016). Long-term exposure to arsenic is associated with upregulated mRNA expression for genes AHR and CYP1A1 in the blood, and blood CYP1A1 mRNA (but not AHR mRNA) is associated with prolonged corrected QT interval. diet Arsenic Study subjects China blood | water, drinking AHR | Arsenic | CYP1A1 Details Long QT Syndrome | regulation of heart rate
43. Zierold KM, et al. (2004). Respondents with arsenic levels of 2 microg/L or greater were statistically more likely to report a history of depression, high blood pressure, circulatory problems, and bypass surgery than were respondents with arsenic concentrations less than 2 microg/L. Arsenic Study subjects United States water Arsenic Details Depressive Disorder | Heart Diseases | Hypertension
44. Osorio-Yáñez C, et al. (2013). Arsenic exposure was positively associated with carotid intima-media thickness in a population of Mexican children with environmental arsenic exposure through drinking water. diet Arsenic Children Mexico plasma | urine | water, drinking Arsenicals | Arsenic | Cacodylic Acid | ICAM1 | monomethylarsonic acid | VCAM1 Details Carotid Intimal Medial Thickness 1 | blood vessel development
45. Jones MR, et al. (2011). National Health and Nutrition Examination Survey (NHANES) At the low to moderate levels typical of the U.S. population, total arsenic, total arsenic minus arsenobetaine, and dimethylarsinate concentrations in urine were not associated with the prevalence of hypertension or with systolic or diastolic blood pressure levels. A weak association of dimethylarsinate with hypertension could not be ruled out. Arsenic | arsenobetaine | Cacodylic Acid Controls for disease:Hypertension | Subjects with disease:Hypertension | Study subjects United States urine Arsenic | arsenobetaine | Cacodylic Acid Details
46. Ghazali AR, et al. (2012). There were significant correlations between heavy metals with subject's age and working period as farmers. age Arsenic | Cadmium | Lead Controls for disease:Hypertension | Subjects with disease:Hypertension | Workers Malaysia nail Arsenic | Cadmium | Lead Details
47. Sanders AP, et al. (2014). In the present study we examined private well water levels of arsenic, cadmium, manganese, and lead across North Carolina, and used a semi-ecologic study design to estimate the association between metal levels and specific birth defect phenotypes. Arsenic | Cadmium | Lead | Manganese Infants or newborns United States Arsenic | Cadmium | Lead | Manganese Details Cleft Lip | Congenital Microtia | Conotruncal cardiac defects | Hypoplastic Left Heart Syndrome | Pyloric Stenosis
48. Ettinger AS, et al. (2014). Modeling the Epidemiologic Transition Study (METS) We sought to examine the distribution of metals exposure and potential associations with cardiometabolic risk factors in the 'Modeling the Epidemiologic Transition Study' (METS), a prospective cohort study designed to assess energy balance and change in body weight, diabetes and cardiovascular disease risk in five countries at different stages of social and economic development. alcohol drinking | diet | socioeconomic status | tobacco Arsenic | Cadmium | Lead | Mercury Study subjects Ghana|Jamaica|
Seychelles|South Africa|
United States
blood Arsenic | Cadmium | Lead | Mercury Details Cardiovascular Diseases | cholesterol metabolic process | glucose metabolic process
49. Thurston GD, et al. (2016). American Cancer Society Cancer Prevention Study II (ACS CPS-II) Long-term fine particulate matter (PM2.5) exposures from fossil fuel combustion, especially coal burning but also from diesel traffic, were associated with increases in ischemic heart disease mortality in this nationwide population. Arsenic | Carbon | Chlorine | Iron | Lead | Manganese | Particulate Matter | Potassium | Selenium | Silicon | Soot | Sulfur Study subjects United States air, ambient | soil Arsenic | Calcium | Carbon | Chlorine | Iron | Lead | Manganese | Nickel | Particulate Matter | Potassium | Selenium | Silicon | Sodium | Soot | Sulfur | Vanadium | Zinc Details Death | Myocardial Ischemia
50. Keil AP, et al. (2017). Lee-Fraumeni Cohort Our analyses suggest that the excess deaths from causes other than respiratory cancers comprise the majority of the excess deaths caused by inhaled arsenic exposure. arsenic trioxide Workers United States air arsenic trioxide Details Death | Heart Diseases | Respiratory Tract Neoplasms
1–50 of 151 results.