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Disease Charcot-Marie-Tooth Disease

These phenotypes are associated with Charcot-Marie-Tooth Disease or its descendants. A phenotype has an inferred association via a curated chemical interaction or a gene-GO annotation or both.

1–50 of 2,309 results.
  Phenotype Disease Chemical Inference Network Gene Inference Network References
1. cell cycle Charcot-Marie-Tooth Disease Inferred via 2 chemicals: Ascorbic Acid | Vincristine Inferred via 1 gene: PMP22 14
2. negative regulation of cell proliferation Charcot-Marie-Tooth Disease Inferred via 2 chemicals: Ascorbic Acid | Vincristine Inferred via 1 gene: PMP22 16
3. cell death Charcot-Marie-Tooth Disease Inferred via 2 chemicals: Ascorbic Acid | Vincristine Inferred via 1 gene: PMP22 34
4. micronucleus organization Charcot-Marie-Tooth Disease Inferred via 2 chemicals: Ascorbic Acid | Vincristine   9
5. positive regulation of nitric oxide biosynthetic process Charcot-Marie-Tooth Disease Inferred via 2 chemicals: Ascorbic Acid | Vincristine   10
6. positive regulation of superoxide dismutase activity Charcot-Marie-Tooth Disease Inferred via 2 chemicals: Ascorbic Acid | Vincristine   12
7. positive regulation of glutathione peroxidase activity Charcot-Marie-Tooth Disease Inferred via 2 chemicals: Ascorbic Acid | Vincristine   13
8. apoptotic process Charcot-Marie-Tooth Disease Inferred via 2 chemicals: Ascorbic Acid | Vincristine   42
9. apoptotic DNA fragmentation Charcot-Marie-Tooth Disease Inferred via 2 chemicals: Ascorbic Acid | Vincristine   11
10. positive regulation of cell death Charcot-Marie-Tooth Disease Inferred via 2 chemicals: Ascorbic Acid | Vincristine   22
11. positive regulation of sodium:potassium-exchanging ATPase activity Charcot-Marie-Tooth Disease Inferred via 2 chemicals: Ascorbic Acid | Vincristine   9
12. lipid oxidation Charcot-Marie-Tooth Disease Inferred via 2 chemicals: Ascorbic Acid | Vincristine   16
13. leukocyte chemotaxis Charcot-Marie-Tooth Disease Inferred via 2 chemicals: Ascorbic Acid | Vincristine   9
14. mitotic cell cycle arrest Charcot-Marie-Tooth Disease Inferred via 2 chemicals: Ascorbic Acid | Vincristine   11
15. positive regulation of apoptotic process Charcot-Marie-Tooth Disease Inferred via 2 chemicals: Ascorbic Acid | Vincristine   16
16. inflammatory response Charcot-Marie-Tooth Disease Inferred via 2 chemicals: Ascorbic Acid | Vincristine   9
17. cell growth Charcot-Marie-Tooth Disease Inferred via 2 chemicals: Ascorbic Acid | Vincristine   13
18. glutathione metabolic process Charcot-Marie-Tooth Disease Inferred via 2 chemicals: Ascorbic Acid | Vincristine   14
19. regulation of mitochondrial membrane potential Charcot-Marie-Tooth Disease Inferred via 2 chemicals: Ascorbic Acid | Vincristine   9
20. positive regulation of calcium-transporting ATPase activity Charcot-Marie-Tooth Disease Inferred via 2 chemicals: Ascorbic Acid | Vincristine   9
21. positive regulation of cell proliferation Charcot-Marie-Tooth Disease Inferred via 2 chemicals: Ascorbic Acid | Vincristine   14
22. positive regulation of mitochondrial membrane potential Charcot-Marie-Tooth Disease Inferred via 2 chemicals: Ascorbic Acid | Vincristine   11
23. positive regulation of NF-kappaB transcription factor activity Charcot-Marie-Tooth Disease Inferred via 2 chemicals: Ascorbic Acid | Vincristine   10
24. cell proliferation Charcot-Marie-Tooth Disease Inferred via 2 chemicals: Ascorbic Acid | Vincristine   11
25. negative regulation of neuron projection development Charcot-Marie-Tooth Disease Inferred via 1 chemical: Vincristine Inferred via 2 genes: PMP22 | TRPV4 13
26. myelination Charcot-Marie-Tooth Disease Inferred via 1 chemical: Vincristine Inferred via 2 genes: MPZ | PMP22 13
27. neuron projection development Charcot-Marie-Tooth Disease Inferred via 1 chemical: Ascorbic Acid Inferred via 1 gene: SLC25A46 4
28. positive regulation of JNK cascade Charcot-Marie-Tooth Disease Inferred via 1 chemical: Ascorbic Acid Inferred via 1 gene: TRPV4 3
29. cholesterol metabolic process Charcot-Marie-Tooth Disease Inferred via 1 chemical: Ascorbic Acid Inferred via 1 gene: PMP22 7
30. actin cytoskeleton organization Charcot-Marie-Tooth Disease Inferred via 1 chemical: Ascorbic Acid Inferred via 1 gene: PMP22 7
31. transmission of nerve impulse Charcot-Marie-Tooth Disease Inferred via 1 chemical: Vincristine Inferred via 1 gene: PMP22 12
32. positive regulation of inflammatory response Charcot-Marie-Tooth Disease Inferred via 1 chemical: Ascorbic Acid Inferred via 1 gene: TRPV4 3
33. positive regulation of autophagosome assembly Charcot-Marie-Tooth Disease Inferred via 1 chemical: Ascorbic Acid Inferred via 1 gene: LRSAM1 3
34. wound healing, spreading of cells Charcot-Marie-Tooth Disease Inferred via 1 chemical: Ascorbic Acid   2
35. positive regulation of chondrocyte differentiation Charcot-Marie-Tooth Disease Inferred via 1 chemical: Ascorbic Acid   2
36. isocitrate metabolic process Charcot-Marie-Tooth Disease Inferred via 1 chemical: Ascorbic Acid   2
37. testosterone secretion Charcot-Marie-Tooth Disease Inferred via 1 chemical: Ascorbic Acid   2
38. estrogen secretion Charcot-Marie-Tooth Disease Inferred via 1 chemical: Ascorbic Acid   2
39. positive regulation of proteasomal ubiquitin-dependent protein catabolic process Charcot-Marie-Tooth Disease Inferred via 1 chemical: Ascorbic Acid   2
40. triglyceride homeostasis Charcot-Marie-Tooth Disease Inferred via 1 chemical: Ascorbic Acid   2
41. response to sodium arsenite Charcot-Marie-Tooth Disease Inferred via 1 chemical: Ascorbic Acid   2
42. hepatocyte differentiation Charcot-Marie-Tooth Disease Inferred via 1 chemical: Ascorbic Acid   2
43. regulation of cytokine production involved in inflammatory response Charcot-Marie-Tooth Disease Inferred via 1 chemical: Ascorbic Acid   2
44. positive regulation of DNA catabolic process Charcot-Marie-Tooth Disease Inferred via 1 chemical: Ascorbic Acid   2
45. positive regulation of biomineral tissue development Charcot-Marie-Tooth Disease Inferred via 1 chemical: Ascorbic Acid   2
46. protein oxidation Charcot-Marie-Tooth Disease Inferred via 1 chemical: Ascorbic Acid   8
47. positive regulation of interleukin-6 production Charcot-Marie-Tooth Disease Inferred via 1 chemical: Ascorbic Acid   2
48. positive regulation of mitochondrial membrane permeability Charcot-Marie-Tooth Disease Inferred via 1 chemical: Ascorbic Acid   4
49. positive regulation of tumor necrosis factor production Charcot-Marie-Tooth Disease Inferred via 1 chemical: Ascorbic Acid   2
50. aerobic respiration Charcot-Marie-Tooth Disease Inferred via 1 chemical: Ascorbic Acid   2
1–50 of 2,309 results.