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Disease Chromosome Aberrations

These are exposure studies associated with the disease and all of its children.

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1–10 of 10 results.
  Reference Associated Study Title Author's Summary Study Factors Stressor Receptors Country Medium Exposure Marker Measurements Outcome
1. Perry MJ, et al. (2016). Organochlorine exposures measured at age 14 and in adulthood were associated with sperm disomy in this sample of high-exposure men, suggesting that the impacts of persistent pollutants on testicular maturation and function require further investigation. 2,2',3',4,4',5-hexachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | PCB 180 Children | Infants or newborns | Study subjects Faroe Islands blood, cord | serum 2,2',3',4,4',5-hexachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | PCB 180 | Polychlorinated Biphenyls Details Aneuploidy | male meiosis chromosome separation
2. Paul S, et al. (2014). We infer that arsenic biotransformation leads to promoter hypomethylation of ERCC2, which in turn inhibits the normal functioning of the Cdk-activating kinase complex, thus affecting DNA repair; this effect was highest among the arsenic exposed individuals with dermatological lesions. Arsenic Controls for disease:Skin Diseases | Subjects with disease:Skin Diseases | Study subjects India blood | hair | leukocyte, mononuclear | nail | urine | water, drinking Arsenic | CDK7 | ERCC2 Details Micronuclei, Chromosome-Defective | Skin Diseases | positive regulation of DNA repair
3. Jurewicz J, et al. (2013). Urinary phthalate metabolites levels were significantly associated with a decrease in sperm motility, testosterone level, and an increase sperm DNA damage and sperm aneuploidy. butylbenzyl phthalate | Dibutyl Phthalate | Diethylhexyl Phthalate | diethyl phthalate | diisononyl phthalate Study subjects Poland urine mono(2-ethyl-5-hydroxyhexyl) phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | monoisononylphthalate Details Aneuploidy | negative regulation of flagellated sperm motility | negative regulation of testosterone biosynthetic process
4. Abdul Hamid Z, et al. (2016). In conclusion, pesticide and fertilizers exposure may contribute to the promotion of nuclear anomalies among Malaysian farmers who are engaged in mixed plantation activities. Fertilizers | Pesticides Workers Malaysia cell, epithelial, buccal Details Chromosome Aberrations
5. Paz-y-Miño C, et al. (2011). The purpose of this study was to diagnose social, health, and genetic aspects of the people affected by glyphosate from aerial spraying; the study population did not present significant chromosomal and DNA alterations, and the most important social impact was fear. glyphosate | Herbicides Subjects with gene influence:GPX1 | Subjects with gene influence:GSTP1 | Study subjects Ecuador Details Chromosome Aberrations
6. McAuliffe ME, et al. (2012). Our findings suggest that exposure to Dichlorodiphenyl Dichloroethylene (p,p'-DDE) may be associated with increased rates of XX, XY, and total sex-chromosome disomy, whereas exposure to polychlorinated biphenyls may be associated with increased rates of YY, XY, and total sex-chromosome disomy, as well as an inverse association with XX disomy. Hydrocarbons, Chlorinated | Polychlorinated Biphenyls Subjects with disease:Infertility, Male United States serum Dichlorodiphenyl Dichloroethylene | Polychlorinated Biphenyls Details Sex Chromosome Aberrations
7. Liu N, et al. (2017). Our results show that workers in an indium production plant were exposed to significantly higher levels of indium and showed higher levels of DNA damage, significantly higher frequencies of chromosomal aberrations, and increased cytokinesis-block micronucleus frequencies. Indium Workers China air, indoor | urine Indium Details Chromosome Aberrations | Micronuclei, Chromosome-Defective | chromosome organization | cytokinesis
8. Scheers H, et al. (2011). Even in an affluent region in Western Europe, where infant mortality is low, days with higher Particulate Matter air pollution are associated with an increased risk of infant mortality. Particulate Matter Infants or newborns Belgium Particulate Matter Details Chromosome Aberrations | Congenital Abnormalities
9. Alves JS, et al. (2016). We observed changes in micronucleus genetic damage (influenced by PON1 polymorphism), superoxide dismutase activity, and levels of inorganic compounds in blood samples of agricultural workers exposed to complex mixtures of pesticides. genetics Pesticides Subjects with gene influence:PON1 | Study subjects | Workers Brazil blood Aluminum | Bromides | Chlorine | Iron | Magnesium | Phosphorus | Sulfur | Zinc Details Agricultural Workers' Diseases | Micronuclei, Chromosome-Defective | Organophosphate Poisoning | positive regulation of superoxide dismutase activity
10. Zhang X, et al. (2015). Our results show that occupational exposure to diesel engine exhaust can induce increases in micronucleus, nucleoplasmic bridge, and nuclear bud frequencies in peripheral blood lymphocytes. Vehicle Emissions Workers China air, indoor | urine 1,12-benzoperylene | 1,2,5,6-dibenzanthracene | 1-hydroxypyrene | 2-hydroxyfluorene | 2-naphthol | 9-phenanthrol | acenaphthene | acenaphthylene | anthracene | benz(a)anthracene | Benzo(a)pyrene | benzo(b)fluoranthene | benzo(k)fluoranthene | Carbon | chrysene | fluoranthene | fluorene | indeno(1,2,3-cd)pyrene | naphthalene | Particulate Matter | phenanthrene | Polycyclic Aromatic Hydrocarbons Details Chromosome Aberrations | Micronuclei, Chromosome-Defective | micronucleus organization
1–10 of 10 results.