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Disease Crush Syndrome

Name Crush Syndrome
Synonyms Crush Syndromes | Syndrome, Crush | Syndromes, Crush
Definition Severe systemic manifestation of trauma and ischemia involving soft tissues, principally skeletal muscle, due to prolonged severe crushing. It leads to increased permeability of the cell membrane and to the release of potassium, enzymes, and myoglobin from within cells. Ischemic renal dysfunction secondary to hypotension and diminished renal perfusion results in acute tubular necrosis and uremia.
Categories Wounds and injuries
MeSH® ID D003444

Top ↑ Ancestors

DiseasesWounds and Injuries Has associated chemicals Has associated genes Has associated exposure references Shock, Traumatic Has associated chemicals Has associated genes Crush Syndrome

Top ↑ Descendants