Skip navigation

Disease Cystic Fibrosis

Name Cystic Fibrosis
Synonyms CF | Cystic Fibrosis of Pancreas | Cystic Fibrosis, Pancreatic | Cystic Fibrosis, Pulmonary | Fibrocystic Disease of Pancreas | Fibrosis, Cystic | Mucoviscidosis | Pancreas Fibrocystic Disease | Pancreas Fibrocystic Diseases | Pancreatic Cystic Fibrosis | Pulmonary Cystic Fibrosis
Definition An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
Categories Digestive system disease | Genetic disease (inborn) | Infant-newborn disease | Respiratory tract disease
MeSH® ID D003550
OMIM® ID 219700
External Links

Top ↑ Ancestors

1. DiseasesDigestive System Diseases Has associated chemicals Has associated genes Has associated exposure references Pancreatic Diseases Has associated chemicals Has associated genes Has associated exposure references Cystic Fibrosis Has associated chemicals Has associated genes
2. DiseasesRespiratory Tract Diseases Has associated chemicals Has associated genes Has associated exposure references Lung Diseases Has associated chemicals Has associated genes Has associated exposure references Cystic Fibrosis Has associated chemicals Has associated genes
3. DiseasesCongenital, Hereditary, and Neonatal Diseases and Abnormalities Has associated chemicals Has associated genes Has associated exposure references Genetic Diseases, Inborn Has associated chemicals Has associated genes Has associated exposure references Cystic Fibrosis Has associated chemicals Has associated genes
4. DiseasesCongenital, Hereditary, and Neonatal Diseases and Abnormalities Has associated chemicals Has associated genes Has associated exposure references Infant, Newborn, Diseases Has associated chemicals Has associated genes Has associated exposure references Cystic Fibrosis Has associated chemicals Has associated genes

Top ↑ Descendants

Cystic Fibrosis Has associated chemicals Has associated genes
  CYSTIC FIBROSIS, MODIFIER OF, 1 Has associated chemicals Has associated genes
  Cystic Fibrosis with Helicobacter Pylori Gastritis, Megaloblastic Anemia, and Subnormal Mentality
  Follicular hamartoma alopecia cystic fibrosis
  Lubani Al Saleh Teebi syndrome