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Disease Deficiency Diseases

These phenotypes are associated with Deficiency Diseases or its descendants. A phenotype has an inferred association via a curated chemical interaction or a gene-GO annotation or both.

1–50 of 6,911 results.
  Phenotype Disease Chemical Inference Network Gene Inference Network References
1. apoptotic process Hyperhomocysteinemia Inferred via 16 chemicals: Catechin | Dizocilpine Maleate | Folic Acid | Glutathione | Homocysteine | Isotretinoin | Levodopa | Melatonin | Methionine | Methotrexate | Niacin | Phenytoin | Plant Extracts | Resveratrol | Simvastatin | Superoxides Inferred via 3 genes: CASP1 | PYCARD | TNF 299
2. positive regulation of cell death Hyperhomocysteinemia Inferred via 15 chemicals: Carbamazepine | Catechin | Dizocilpine Maleate | Folic Acid | Glutathione | Isotretinoin | Melatonin | Methotrexate | Niacin | Phenytoin | Plant Extracts | Resveratrol | Simvastatin | Superoxides | Vitamin B 12   110
3. cell proliferation Hyperhomocysteinemia Inferred via 15 chemicals: Catechin | Dizocilpine Maleate | Folic Acid | Glutathione | Homocysteine | Isotretinoin | Levodopa | Melatonin | Methionine | Methotrexate | Norethindrone Acetate | Phenytoin | Plant Extracts | Resveratrol | Simvastatin   230
4. cell death Hyperhomocysteinemia Inferred via 14 chemicals: Carbamazepine | Catechin | Dizocilpine Maleate | Glutathione | Homocysteine | Levodopa | Melatonin | Methionine | Methotrexate | Phenytoin | Plant Extracts | Resveratrol | Simvastatin | Superoxides   136
5. membrane lipid catabolic process Hyperhomocysteinemia Inferred via 12 chemicals: Catechin | Dizocilpine Maleate | Glutathione | Isotretinoin | Levodopa | Melatonin | Methionine | Niacin | Plant Extracts | Resveratrol | Simvastatin | Superoxides   121
6. lipid oxidation Hyperhomocysteinemia Inferred via 11 chemicals: Carbamazepine | Catechin | Folic Acid | Glutathione | Melatonin | Methionine | Methotrexate | Plant Extracts | Resveratrol | Simvastatin | Vitamin B 12   78
7. lipid catabolic process Hyperhomocysteinemia Inferred via 11 chemicals: Catechin | Dizocilpine Maleate | Glutathione | Levodopa | Melatonin | Methionine | Methotrexate | Niacin | Plant Extracts | Resveratrol | Simvastatin   98
8. glutathione biosynthetic process Hyperhomocysteinemia Inferred via 11 chemicals: Dizocilpine Maleate | Folic Acid | Glutathione | Melatonin | Methionine | Methotrexate | Phenytoin | Plant Extracts | Resveratrol | Simvastatin | Vitamin B 12   80
9. cell death Magnesium Deficiency Inferred via 11 chemicals: Cisplatin | Cocaine | Digoxin | Doxorubicin | Gentamicins | Hydrochlorothiazide | Magnesium | Omeprazole | Ribavirin | Rosiglitazone | Sirolimus   115
10. apoptotic process Magnesium Deficiency Inferred via 11 chemicals: Cisplatin | Cocaine | Digoxin | Doxorubicin | Epinephrine | Gentamicins | Magnesium Sulfate | Omeprazole | Ribavirin | Rosiglitazone | Sirolimus   300
11. cell cycle Hyperhomocysteinemia Inferred via 10 chemicals: Glutathione | Homocysteine | Isotretinoin | Melatonin | Methionine | Methotrexate | Niacin | Plant Extracts | Resveratrol | Simvastatin   50
12. glutathione metabolic process Hyperhomocysteinemia Inferred via 10 chemicals: Carbamazepine | Catechin | Folic Acid | Glutathione | Melatonin | Methotrexate | Plant Extracts | Resveratrol | Simvastatin | Vitamin B 12   302
13. response to oxidative stress Hyperhomocysteinemia Inferred via 10 chemicals: Glutathione | Homocysteine | Isotretinoin | Levodopa | Melatonin | Methionine | Niacin | Plant Extracts | Resveratrol | Simvastatin   111
14. positive regulation of apoptotic process Hyperhomocysteinemia Inferred via 9 chemicals: Carbamazepine | Glutathione | Melatonin | Methionine | Methotrexate | Plant Extracts | Resveratrol | Simvastatin | Superoxides Inferred via 3 genes: CASP1 | PYCARD | TNF 108
15. apoptotic process Vitamin B 12 Deficiency Inferred via 9 chemicals: Chlorambucil | Colchicine | Cyclophosphamide | Homocysteine | Metformin | Octreotide | Phenobarbital | Phenytoin | S-Adenosylmethionine   78
16. cell proliferation Vitamin B 12 Deficiency Inferred via 9 chemicals: Colchicine | Cyclophosphamide | Homocysteine | Metformin | Nitrous Oxide | Octreotide | Phenobarbital | Phenytoin | S-Adenosylmethionine   51
17. positive regulation of cell death Osteomalacia Inferred via 9 chemicals: Cadmium | Calcitriol | Carbamazepine | Cholecalciferol | Folic Acid | Ifosfamide | Phenobarbital | Phenytoin | Tenofovir   27
18. cell death Vitamin B 12 Deficiency Inferred via 9 chemicals: Chlorambucil | Colchicine | Dextromethorphan | Homocysteine | Metformin | Methylmalonic Acid | Octreotide | Phenobarbital | Phenytoin   28
19. cell proliferation Magnesium Deficiency Inferred via 9 chemicals: Cisplatin | Cocaine | Doxorubicin | Epinephrine | Gentamicins | Omeprazole | Ribavirin | Rosiglitazone | Sirolimus   200
20. lipid catabolic process Magnesium Deficiency Inferred via 9 chemicals: Cisplatin | Cocaine | Doxorubicin | Epinephrine | Gentamicins | Magnesium Sulfate | Omeprazole | Rosiglitazone | Sirolimus   59
21. positive regulation of superoxide dismutase activity Hyperhomocysteinemia Inferred via 8 chemicals: Catechin | Folic Acid | Glutathione | Melatonin | Methotrexate | Plant Extracts | Resveratrol | Vitamin B 12 Inferred via 1 gene: TNF 61
22. positive regulation of cell proliferation Hyperhomocysteinemia Inferred via 8 chemicals: Catechin | Dizocilpine Maleate | Folic Acid | Glutathione | Melatonin | Methotrexate | Plant Extracts | Resveratrol Inferred via 1 gene: TNF 74
23. cell proliferation Osteomalacia Inferred via 8 chemicals: Cadmium | Calcitriol | Cholecalciferol | Folic Acid | Ifosfamide | Phenobarbital | Phenytoin | Phosphates   113
24. cell death Osteomalacia Inferred via 8 chemicals: Aluminum | Cadmium | Calcitriol | Carbamazepine | Phenobarbital | Phenytoin | Phosphates | Tenofovir   24
25. regulation of blood pressure Magnesium Deficiency Inferred via 8 chemicals: Cocaine | Digoxin | Epinephrine | Hydrochlorothiazide | Magnesium | Magnesium Sulfate | Rosiglitazone | Sirolimus   141
26. positive regulation of reactive oxygen species biosynthetic process Hyperhomocysteinemia Inferred via 8 chemicals: Dizocilpine Maleate | Glutathione | Melatonin | Methionine | Methotrexate | Plant Extracts | Resveratrol | Superoxides   66
27. regulation of blood pressure Hyperhomocysteinemia Inferred via 8 chemicals: Folic Acid | Glutathione | Levodopa | Melatonin | Methionine | Niacin | Plant Extracts | Simvastatin   51
28. apoptotic DNA fragmentation Hyperhomocysteinemia Inferred via 8 chemicals: Homocysteine | Isotretinoin | Levodopa | Melatonin | Methionine | Plant Extracts | Resveratrol | Simvastatin   46
29. reactive oxygen species biosynthetic process Hyperhomocysteinemia Inferred via 8 chemicals: Catechin | Dizocilpine Maleate | Glutathione | Melatonin | Methionine | Plant Extracts | Resveratrol | Superoxides   58
30. apoptotic DNA fragmentation Magnesium Deficiency Inferred via 8 chemicals: Cisplatin | Cocaine | Doxorubicin | Epinephrine | Magnesium | Omeprazole | Rosiglitazone | Sirolimus   46
31. calcium-mediated signaling Hyperhomocysteinemia Inferred via 7 chemicals: Dizocilpine Maleate | Homocysteine | Melatonin | Niacin | Resveratrol | Simvastatin | Vitamin B 12 Inferred via 1 gene: TNF 20
32. vasoconstriction Magnesium Deficiency Inferred via 7 chemicals: Cisplatin | Cocaine | Digoxin | Epinephrine | Magnesium Sulfate | Rosiglitazone | Sirolimus   50
33. cell growth Hyperhomocysteinemia Inferred via 7 chemicals: Carbamazepine | Catechin | Glutathione | Melatonin | Methotrexate | Plant Extracts | Resveratrol   16
34. cell growth Magnesium Deficiency Inferred via 7 chemicals: Cisplatin | Cocaine | Doxorubicin | Gentamicins | Omeprazole | Ribavirin | Sirolimus   30
35. membrane lipid catabolic process Magnesium Deficiency Inferred via 7 chemicals: Cisplatin | Cocaine | Doxorubicin | Epinephrine | Gentamicins | Omeprazole | Rosiglitazone   37
36. nitric oxide biosynthetic process Hyperhomocysteinemia Inferred via 7 chemicals: Melatonin | Methionine | Methotrexate | Niacin | Plant Extracts | Resveratrol | Simvastatin   37
37. negative regulation of superoxide dismutase activity Hyperhomocysteinemia Inferred via 7 chemicals: Carbamazepine | Folic Acid | Glutathione | Melatonin | Plant Extracts | Resveratrol | Vitamin B 12   33
38. regulation of organ growth Hyperhomocysteinemia Inferred via 7 chemicals: Glutathione | Homocysteine | Isotretinoin | Melatonin | Methionine | Plant Extracts | Simvastatin   25
39. protein oxidation Hyperhomocysteinemia Inferred via 7 chemicals: Carbamazepine | Glutathione | Methionine | Methotrexate | Plant Extracts | Resveratrol | Simvastatin   36
40. positive regulation of cell death Magnesium Deficiency Inferred via 7 chemicals: Cisplatin | Digoxin | Doxorubicin | Epinephrine | Gentamicins | Rosiglitazone | Sirolimus   75
41. positive regulation of glutathione peroxidase activity Hyperhomocysteinemia Inferred via 7 chemicals: Folic Acid | Glutathione | Melatonin | Methotrexate | Plant Extracts | Resveratrol | Vitamin B 12   43
42. DNA damage response, detection of DNA damage Hyperhomocysteinemia Inferred via 7 chemicals: Glutathione | Melatonin | Methionine | Phenytoin | Plant Extracts | Resveratrol | Simvastatin   34
43. regulation of mitochondrial membrane potential Hyperhomocysteinemia Inferred via 7 chemicals: Dizocilpine Maleate | Glutathione | Melatonin | Phenytoin | Plant Extracts | Resveratrol | Simvastatin   54
44. regulation of heart rate Hyperhomocysteinemia Inferred via 7 chemicals: Dizocilpine Maleate | Levodopa | Methionine | Plant Extracts | Simvastatin | Vitamin B 12 | Vitamin B 6   22
45. superoxide dismutase activity Hyperhomocysteinemia Inferred via 7 chemicals: Glutathione | Melatonin | Methionine | Methotrexate | Plant Extracts | Resveratrol | Simvastatin   69
46. mitotic cell cycle arrest Hyperhomocysteinemia Inferred via 7 chemicals: Folic Acid | Glutathione | Melatonin | Methionine | Methotrexate | Plant Extracts | Resveratrol   58
47. glutathione biosynthetic process Magnesium Deficiency Inferred via 7 chemicals: Cisplatin | Cocaine | Doxorubicin | Gentamicins | Omeprazole | Rosiglitazone | Sirolimus   40
48. positive regulation of nitric oxide biosynthetic process Hyperhomocysteinemia Inferred via 6 chemicals: Carbamazepine | Catechin | Dizocilpine Maleate | Plant Extracts | Resveratrol | Simvastatin Inferred via 1 gene: TNF 28
49. cell proliferation Folic Acid Deficiency Inferred via 6 chemicals: Ethinyl Estradiol | Folic Acid | Hydroxyurea | Phenobarbital | Phenytoin | S-Adenosylmethionine   27
50. cell death Folic Acid Deficiency Inferred via 6 chemicals: Dextromethorphan | Ethinyl Estradiol | Hydroxyurea | Methyldopa | Phenobarbital | Phenytoin   19
1–50 of 6,911 results.