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Disease Deficiency Diseases

These phenotypes are associated with Deficiency Diseases or its descendants. A phenotype has an inferred association via a curated chemical interaction or a gene-GO annotation or both.

1–50 of 6,748 results.
  Phenotype Disease Chemical Inference Network Gene Inference Network References
1. apoptotic process Hyperhomocysteinemia Inferred via 16 chemicals: Catechin | Dizocilpine Maleate | Folic Acid | Glutathione | Homocysteine | Isotretinoin | Levodopa | Melatonin | Methionine | Methotrexate | Niacin | Phenytoin | Plant Extracts | Resveratrol | Simvastatin | Superoxides Inferred via 3 genes: CASP1 | PYCARD | TNF 298
2. cell proliferation Hyperhomocysteinemia Inferred via 15 chemicals: Catechin | Dizocilpine Maleate | Folic Acid | Glutathione | Homocysteine | Isotretinoin | Levodopa | Melatonin | Methionine | Methotrexate | Norethindrone Acetate | Phenytoin | Plant Extracts | Resveratrol | Simvastatin Inferred via 1 gene: TNF 231
3. positive regulation of cell death Hyperhomocysteinemia Inferred via 15 chemicals: Carbamazepine | Catechin | Dizocilpine Maleate | Folic Acid | Glutathione | Isotretinoin | Melatonin | Methotrexate | Niacin | Phenytoin | Plant Extracts | Resveratrol | Simvastatin | Superoxides | Vitamin B 12   110
4. cell death Hyperhomocysteinemia Inferred via 14 chemicals: Carbamazepine | Catechin | Dizocilpine Maleate | Glutathione | Homocysteine | Levodopa | Melatonin | Methionine | Methotrexate | Phenytoin | Plant Extracts | Resveratrol | Simvastatin | Superoxides   135
5. membrane lipid catabolic process Hyperhomocysteinemia Inferred via 12 chemicals: Catechin | Dizocilpine Maleate | Glutathione | Isotretinoin | Levodopa | Melatonin | Methionine | Niacin | Plant Extracts | Resveratrol | Simvastatin | Superoxides   121
6. cell death Magnesium Deficiency Inferred via 11 chemicals: Cisplatin | Cocaine | Digoxin | Doxorubicin | Gentamicins | Hydrochlorothiazide | Magnesium | Omeprazole | Ribavirin | Rosiglitazone | Sirolimus   113
7. lipid catabolic process Hyperhomocysteinemia Inferred via 11 chemicals: Catechin | Dizocilpine Maleate | Glutathione | Levodopa | Melatonin | Methionine | Methotrexate | Niacin | Plant Extracts | Resveratrol | Simvastatin   95
8. apoptotic process Magnesium Deficiency Inferred via 11 chemicals: Cisplatin | Cocaine | Digoxin | Doxorubicin | Epinephrine | Gentamicins | Magnesium Sulfate | Omeprazole | Ribavirin | Rosiglitazone | Sirolimus   295
9. response to oxidative stress Hyperhomocysteinemia Inferred via 10 chemicals: Glutathione | Homocysteine | Isotretinoin | Levodopa | Melatonin | Methionine | Niacin | Plant Extracts | Resveratrol | Simvastatin   111
10. glutathione biosynthetic process Hyperhomocysteinemia Inferred via 10 chemicals: Dizocilpine Maleate | Folic Acid | Glutathione | Melatonin | Methionine | Methotrexate | Phenytoin | Plant Extracts | Resveratrol | Vitamin B 12   77
11. cell cycle Hyperhomocysteinemia Inferred via 10 chemicals: Glutathione | Homocysteine | Isotretinoin | Melatonin | Methionine | Methotrexate | Niacin | Plant Extracts | Resveratrol | Simvastatin   50
12. positive regulation of apoptotic process Hyperhomocysteinemia Inferred via 9 chemicals: Carbamazepine | Glutathione | Melatonin | Methionine | Methotrexate | Plant Extracts | Resveratrol | Simvastatin | Superoxides Inferred via 3 genes: CASP1 | PYCARD | TNF 108
13. cell proliferation Magnesium Deficiency Inferred via 9 chemicals: Cisplatin | Cocaine | Doxorubicin | Epinephrine | Gentamicins | Omeprazole | Ribavirin | Rosiglitazone | Sirolimus   198
14. cell death Vitamin B 12 Deficiency Inferred via 9 chemicals: Chlorambucil | Colchicine | Dextromethorphan | Homocysteine | Metformin | Methylmalonic Acid | Octreotide | Phenobarbital | Phenytoin   28
15. cell proliferation Vitamin B 12 Deficiency Inferred via 9 chemicals: Colchicine | Cyclophosphamide | Homocysteine | Metformin | Nitrous Oxide | Octreotide | Phenobarbital | Phenytoin | S-Adenosylmethionine   51
16. lipid catabolic process Magnesium Deficiency Inferred via 9 chemicals: Cisplatin | Cocaine | Doxorubicin | Epinephrine | Gentamicins | Magnesium Sulfate | Omeprazole | Rosiglitazone | Sirolimus   57
17. apoptotic process Vitamin B 12 Deficiency Inferred via 9 chemicals: Chlorambucil | Colchicine | Cyclophosphamide | Homocysteine | Metformin | Octreotide | Phenobarbital | Phenytoin | S-Adenosylmethionine   78
18. lipid oxidation Hyperhomocysteinemia Inferred via 9 chemicals: Carbamazepine | Catechin | Glutathione | Melatonin | Methionine | Methotrexate | Plant Extracts | Resveratrol | Simvastatin   64
19. positive regulation of cell proliferation Hyperhomocysteinemia Inferred via 8 chemicals: Catechin | Dizocilpine Maleate | Folic Acid | Glutathione | Melatonin | Methotrexate | Plant Extracts | Resveratrol Inferred via 1 gene: TNF 73
20. regulation of blood pressure Hyperhomocysteinemia Inferred via 8 chemicals: Folic Acid | Glutathione | Levodopa | Melatonin | Methionine | Niacin | Plant Extracts | Simvastatin   51
21. apoptotic DNA fragmentation Hyperhomocysteinemia Inferred via 8 chemicals: Homocysteine | Isotretinoin | Levodopa | Melatonin | Methionine | Plant Extracts | Resveratrol | Simvastatin   46
22. glutathione metabolic process Hyperhomocysteinemia Inferred via 8 chemicals: Carbamazepine | Catechin | Glutathione | Melatonin | Methotrexate | Plant Extracts | Resveratrol | Simvastatin   283
23. cell proliferation Osteomalacia Inferred via 8 chemicals: Cadmium | Calcitriol | Cholecalciferol | Folic Acid | Ifosfamide | Phenobarbital | Phenytoin | Phosphates   113
24. apoptotic DNA fragmentation Magnesium Deficiency Inferred via 8 chemicals: Cisplatin | Cocaine | Doxorubicin | Epinephrine | Magnesium | Omeprazole | Rosiglitazone | Sirolimus   46
25. cell death Osteomalacia Inferred via 8 chemicals: Aluminum | Cadmium | Calcitriol | Carbamazepine | Phenobarbital | Phenytoin | Phosphates | Tenofovir   24
26. positive regulation of cell death Osteomalacia Inferred via 8 chemicals: Cadmium | Carbamazepine | Cholecalciferol | Folic Acid | Ifosfamide | Phenobarbital | Phenytoin | Tenofovir   25
27. regulation of blood pressure Magnesium Deficiency Inferred via 8 chemicals: Cocaine | Digoxin | Epinephrine | Hydrochlorothiazide | Magnesium | Magnesium Sulfate | Rosiglitazone | Sirolimus   141
28. reactive oxygen species biosynthetic process Hyperhomocysteinemia Inferred via 8 chemicals: Catechin | Dizocilpine Maleate | Glutathione | Melatonin | Methionine | Plant Extracts | Resveratrol | Superoxides   57
29. positive regulation of reactive oxygen species biosynthetic process Hyperhomocysteinemia Inferred via 8 chemicals: Dizocilpine Maleate | Glutathione | Melatonin | Methionine | Methotrexate | Plant Extracts | Resveratrol | Superoxides   66
30. calcium-mediated signaling Hyperhomocysteinemia Inferred via 7 chemicals: Dizocilpine Maleate | Homocysteine | Melatonin | Niacin | Resveratrol | Simvastatin | Vitamin B 12 Inferred via 1 gene: TNF 20
31. superoxide dismutase activity Hyperhomocysteinemia Inferred via 7 chemicals: Glutathione | Melatonin | Methionine | Methotrexate | Plant Extracts | Resveratrol | Simvastatin   66
32. vasoconstriction Magnesium Deficiency Inferred via 7 chemicals: Cisplatin | Cocaine | Digoxin | Epinephrine | Magnesium Sulfate | Rosiglitazone | Sirolimus   50
33. protein oxidation Hyperhomocysteinemia Inferred via 7 chemicals: Carbamazepine | Glutathione | Methionine | Methotrexate | Plant Extracts | Resveratrol | Simvastatin   36
34. membrane lipid catabolic process Magnesium Deficiency Inferred via 7 chemicals: Cisplatin | Cocaine | Doxorubicin | Epinephrine | Gentamicins | Omeprazole | Rosiglitazone   37
35. regulation of mitochondrial membrane potential Hyperhomocysteinemia Inferred via 7 chemicals: Dizocilpine Maleate | Glutathione | Melatonin | Phenytoin | Plant Extracts | Resveratrol | Simvastatin   53
36. regulation of organ growth Hyperhomocysteinemia Inferred via 7 chemicals: Glutathione | Homocysteine | Isotretinoin | Melatonin | Methionine | Plant Extracts | Simvastatin   25
37. positive regulation of cell death Magnesium Deficiency Inferred via 7 chemicals: Cisplatin | Digoxin | Doxorubicin | Epinephrine | Gentamicins | Rosiglitazone | Sirolimus   75
38. DNA damage response, detection of DNA damage Hyperhomocysteinemia Inferred via 7 chemicals: Glutathione | Melatonin | Methionine | Phenytoin | Plant Extracts | Resveratrol | Simvastatin   34
39. mitotic cell cycle arrest Hyperhomocysteinemia Inferred via 7 chemicals: Folic Acid | Glutathione | Melatonin | Methionine | Methotrexate | Plant Extracts | Resveratrol   58
40. regulation of heart rate Hyperhomocysteinemia Inferred via 7 chemicals: Dizocilpine Maleate | Levodopa | Methionine | Plant Extracts | Simvastatin | Vitamin B 12 | Vitamin B 6   22
41. positive regulation of nitric oxide biosynthetic process Hyperhomocysteinemia Inferred via 6 chemicals: Carbamazepine | Catechin | Dizocilpine Maleate | Plant Extracts | Resveratrol | Simvastatin Inferred via 1 gene: TNF 28
42. positive regulation of superoxide dismutase activity Hyperhomocysteinemia Inferred via 6 chemicals: Catechin | Glutathione | Melatonin | Methotrexate | Plant Extracts | Resveratrol Inferred via 1 gene: TNF 46
43. cell death Folic Acid Deficiency Inferred via 6 chemicals: Dextromethorphan | Ethinyl Estradiol | Hydroxyurea | Methyldopa | Phenobarbital | Phenytoin   19
44. glutathione biosynthetic process Magnesium Deficiency Inferred via 6 chemicals: Cisplatin | Doxorubicin | Gentamicins | Omeprazole | Rosiglitazone | Sirolimus   37
45. triglyceride biosynthetic process Hyperhomocysteinemia Inferred via 6 chemicals: Folic Acid | Methionine | Niacin | Plant Extracts | Resveratrol | Vitamin B 12   43
46. cell proliferation Folic Acid Deficiency Inferred via 6 chemicals: Ethinyl Estradiol | Folic Acid | Hydroxyurea | Phenobarbital | Phenytoin | S-Adenosylmethionine   27
47. cell differentiation Hyperhomocysteinemia Inferred via 6 chemicals: Homocysteine | Levodopa | Melatonin | Plant Extracts | Resveratrol | Simvastatin   18
48. reactive oxygen species metabolic process Hyperhomocysteinemia Inferred via 6 chemicals: Dizocilpine Maleate | Glutathione | Melatonin | Phenytoin | Plant Extracts | Resveratrol   38
49. superoxide dismutase activity Magnesium Deficiency Inferred via 6 chemicals: Cisplatin | Cocaine | Doxorubicin | Magnesium Sulfate | Omeprazole | Rosiglitazone   35
50. apoptotic process Folic Acid Deficiency Inferred via 6 chemicals: Ethinyl Estradiol | Folic Acid | Hydroxyurea | Phenobarbital | Phenytoin | S-Adenosylmethionine   24
1–50 of 6,748 results.