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Disease Gastrointestinal Diseases

These are exposure studies associated with the disease and all of its children.

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1–34 of 34 results.
  Reference Associated Study Title Author's Summary Study Factors Stressor Receptors Country Medium Exposure Marker Measurements Outcome
1. Howsam M, et al. (2004). These results generate the hypothesis that exposure to mono-ortho polychlorinated biphenyls contributes to human colorectal cancer development. 2,2',3',4,4',5-hexachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,4'-trichlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,5,2',5'-tetrachlorobiphenyl | alpha-hexachlorocyclohexane | beta-hexachlorocyclohexane | DDT | Dichlorodiphenyl Dichloroethylene | Hexachlorobenzene | Lindane | PCB 180 | Polychlorinated Biphenyls Controls for disease:Colorectal Neoplasms | Subjects with disease:Colorectal Neoplasms | Study subjects Spain serum 2,2',3',4,4',5-hexachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,4'-trichlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,5,2',5'-tetrachlorobiphenyl | alpha-hexachlorocyclohexane | beta-hexachlorocyclohexane | DDT | Dichlorodiphenyl Dichloroethylene | Hexachlorobenzene | Lindane | PCB 180 Details Colorectal Neoplasms
2. Dallaire F, et al. (2004). These results show a possible association between prenatal exposure to organochlorines and acute infections early in life in this Inuit population. 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | Hydrocarbons, Chlorinated Infants or newborns | Mothers Canada plasma 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | Hydrocarbons, Chlorinated Details Gastrointestinal Diseases | Otitis Media | Respiratory Tract Infections
3. Lee WJ, et al. (2007). Agricultural Health Study (AHS) This explorative study suggests an association between the incidence of colorectal cancer and use of certain pesticides, in particularly chlorpyrifos and aldicarb, although some findings could be due to chance. age | body mass index | tobacco 2,4-Dichlorophenoxyacetic Acid | Aldicarb | Carbaryl | Chlorpyrifos | Fonofos | Toxaphene Workers United States Details Agricultural Workers' Diseases | Colorectal Neoplasms | Rectal Neoplasms
4. Le NT, et al. (2016). Health Professionals Follow-up Study (HPFS) | Nurses' Health Study (NHS) Results from these two large prospective cohort studies do not support the hypothesis that higher intake of heterocyclic amine intake per se substantially increases risk of colorectal cancer. However, we observed positive association between 2-amino-1-methyl-6-phenylimidazo pyridine from red meat, but not from white meat, and proximal colon cancers. 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine Workers United States Details Colorectal Neoplasms
5. Lerro C, et al. (2014). Agricultural Health Study (AHS) The associations between acetochlor and colorectal and lung cancer are novel; however, due to lack of exposure-response trend, small number of exposed cases, and relatively short time between use and cancer development, these findings warrant caution in interpretation and further investigation. acetochlor Workers United States Details Agricultural Workers' Diseases | Colorectal Neoplasms | Lung Neoplasms
6. Lerro CC, et al. (2015). Agricultural Health Study (AHS) The associations between acetochlor use and lung cancer, colorectal cancer, melanoma and pancreatic cancer are suggestive; however, the lack of exposure-response trends, small number of exposed cases, and relatively short time between acetochlor use and cancer development prohibit definitive conclusions. acetochlor Workers United States Details Agricultural Workers' Diseases | Colorectal Neoplasms | Lung Neoplasms | Melanoma | Pancreatic Neoplasms
7. López-Abente G, et al. (2012). Statistically significant relative risks for colorectal cancer mortality at a municipal level were detected in the vicinity of mining industry, paper and wood production, food and beverage sector, metal production and processing installations, and ceramics. Air Pollutants Study subjects Spain air, outdoor 1,1,1-trichloroethane | Ammonia | anthracene | Antimony | Arsenicals | Arsenic | Benzene | beta-hexachlorocyclohexane | Cadmium | Cadmium Compounds | Carbon Dioxide | Carbon Monoxide | Carbon Tetrachloride | Chlorine | Chlorine Compounds | Chlorofluorocarbons | Chloroform | Chromium | Chromium Compounds | Cobalt | Diethylhexyl Phthalate | Dioxins | ethylene dichloride | Ethylene Oxide | Fluorine | Fluorine Compounds | Hexachlorobenzene | Hydrogen Cyanide | Lead | Manganese | Manganese Compounds | Mercury | Mercury Compounds | Methane | Methylene Chloride | naphthalene | Nickel | Nitrogen Oxides | Nitrous Oxide | Particulate Matter | Pentachlorophenol | Polychlorinated Biphenyls | Sulfur Oxides | Tetrachloroethylene | Thallium | trichlorobenzene | Trichloroethylene | Vanadium | Vanadium Compounds | Vinyl Chloride | Zinc | Zinc Compounds Details Colorectal Neoplasms | Death
8. Ranzi A, et al. (2011). No increased risk of mortality and morbidity was found in the entire area among people living close to incinerators. The internal analysis of the cohort based on dispersion modeling found excesses of mortality for some cancer types in the highest exposure categories, especially in women. People in the highest heavy metal exposure categories tended to have a lower socioeconomic status than those in the lowest categories. The interpretation of the findings is limited given the pilot nature of the study sex | socioeconomic status Air Pollutants Study subjects Italy waste, industrial Cadmium | Dioxins | Mercury | Metals, Heavy | Nitrogen Dioxide | Particulate Matter Details Breast Neoplasms | Colorectal Neoplasms | Death | Liver Neoplasms | Neoplasms | Stomach Neoplasms
9. Andreotti G, et al. (2010). Agricultural Health Study (AHS) Using data from the Agricultural Health Study, we examined the association between body mass index (BMI) and the risk of cancer at 17 sites and the interaction between BMI and pesticide use. body mass index | tobacco alachlor | Atrazine | Carbaryl | Carbofuran | chlorimuron ethyl | Chlorpyrifos | cyanazine | DDT | Diazinon | EPTC | Fonofos | glyphosate | Hydrocarbons, Chlorinated | imazethapyr | Malathion | methyl bromide | metolachlor | metribuzin | Organophosphates | pendimethalin | Permethrin | terbufos | Trifluralin Study subjects | Workers United States Details Agricultural Workers' Diseases | Breast Neoplasms | Colonic Neoplasms | Lung Neoplasms
10. Purdue MP, et al. (2007). Agricultural Health Study (AHS) Our analysis of data from the Agricultural Health Study cohort suggests that, overall, use of organochlorine insecticides was not related to cancer risk. We did, however, observe associations among specific chemicals, some of which (lindane and NHL, chlordane/heptachlor and leukemia) are supported by previously published studies and warrant further investigation. Aldrin | Chlordan | DDT | Dieldrin | Heptachlor | Lindane | Toxaphene Workers United States Details Agricultural Workers' Diseases | Colonic Neoplasms | Leukemia | Lung Neoplasms | Lymphoma, Non-Hodgkin | Melanoma | Neoplasms | Rectal Neoplasms
11. Sanders AP, et al. (2014). In the present study we examined private well water levels of arsenic, cadmium, manganese, and lead across North Carolina, and used a semi-ecologic study design to estimate the association between metal levels and specific birth defect phenotypes. Arsenic | Cadmium | Lead | Manganese Infants or newborns United States Arsenic | Cadmium | Lead | Manganese Details Cleft Lip | Congenital Microtia | Conotruncal cardiac defects | Hypoplastic Left Heart Syndrome | Pyloric Stenosis
12. Paris C, et al. (2017). Asbestos-Related Diseases Cohort (ARDCo) | Asbestos-Related Diseases Cohort (ARDCo-Nut) Our findings provide support for an association between occupational exposure to asbestos and colon cancer incidence in men. Asbestos Study subjects France Details Colonic Neoplasms
13. Rahman MB, et al. (2014). We found weak evidence of a positive association between incidence of colorectal cancer in men and total trihalomethanes concentration in water supplies and a somewhat stronger association for bromoform concentration. sex bromodichloromethane | bromoform | chlorodibromomethane | Chloroform | Trihalomethanes Study subjects Australia water, drinking bromodichloromethane | bromoform | chlorodibromomethane | Chloroform | Trihalomethanes Details Colorectal Neoplasms
14. Lynch SM, et al. (2006). Agricultural Health Study (AHS) We did not find any clear, consistent associations between cyanazine exposure and any cancer analyzed. cyanazine Workers United States Details Colonic Neoplasms | Hematologic Neoplasms | Lung Neoplasms | Lymphoma, Non-Hodgkin | Neoplasms | Prostatic Neoplasms
15. Samanic C, et al. (2006). Agricultural Health Study (AHS) Although associations between exposure and lung and colon cancer were observed, we did not find clear evidence for an association between dicamba exposure and cancer risk. Dicamba Workers United States Details Colonic Neoplasms | Lung Neoplasms
16. Song L, et al. (2014). These results indicated that p,p'-DDE promoted colorectal cancer cell proliferation through Wnt/beta-catenin and Hedgehog/Gli1 signalings mediated by oxidative stress. Dichlorodiphenyl Dichloroethylene China Details Colorectal Neoplasms | gene expression | positive regulation of signaling | response to oxidative stress
17. Tsai RJ, et al. (2014). National Pesticide Information Center (NPIC) | Sentinel Event Notification System for Occupational Risks (SENSOR) Notes from the Field: Acute Illness Associated with Use of Pest Strips - Seven U.S. States and Canada, 2000-2013 Dichlorvos Subjects with disease:Acute Disease Canada|United States Details Acute Disease | Gastrointestinal Diseases | Neurologic Manifestations | Respiratory Tract Diseases
18. Attfield MD, et al. (2012). Diesel Exhaust in Miners Study (DEMS) The study findings provide further evidence that exposure to diesel exhaust increases risk of mortality from lung cancer and have important public health implications. Dust | Radon | Vehicle Emissions Workers United States Carbon | Dust | Radon Details Esophageal Neoplasms | Lung Neoplasms | Neoplasms | Pneumoconiosis
19. van Bemmel DM, et al. (2008). Agricultural Health Study (AHS) In this analysis, S-Ethyl-N,N-dipropylthiocarbamate use appeared to be associated with colon cancer and leukemia. EPTC Workers United States Details Agricultural Workers' Diseases | Colonic Neoplasms | Leukemia | Neoplasms
20. Amin R, et al. (2017). We find that gadolinium use during pregnancy is unlikely to be associated with adverse effects in infants during the neonatal period. Gadolinium Infants or newborns | Pregnant females United States blood, cord Gadolinium Details Birth Weight | Bone Diseases, Metabolic | Chorioamnionitis | Diabetes, Gestational | Ductus Arteriosus, Patent | Enterocolitis, Necrotizing | Fetal Growth Retardation | Hyperbilirubinemia, Neonatal | Hypertension, Pregnancy-Induced | Lung Diseases | Obstetric Labor, Premature | Oligohydramnios | Prenatal Exposure Delayed Effects | Respiratory Distress Syndrome, Newborn | Retinopathy of Prematurity
21. Koutros S, et al. (2009). Agricultural Health Study (AHS) Significant excess risks of bladder and colon cancers were observed in the Agricultural Health Study among applicators exposed to the heterocyclic aromatic amine herbicide imazethapyr. imazethapyr Workers United States Details Agricultural Workers' Diseases | Colonic Neoplasms | Urinary Bladder Neoplasms
22. Liao LM, et al. (2016). Shanghai Men's Health Study (SMHS) | Shanghai Women's Health Study (SWHS) In conclusion, our findings, though limited by small numbers of cases, suggest that lead exposure is associated with an increased risk of several cancers, in particular, meningioma, brain cancer, and kidney cancer. Lead Study subjects China Lead Details Brain Neoplasms | Kidney Neoplasms | Lung Neoplasms | Meningioma | Stomach Neoplasms
23. Barry KH, et al. (2012). Agricultural Health Study (AHS) In summary, in this population of primarily white male private applicators in the Agricultural Health Study with follow-up from 1993 through 2007, we observed little evidence of associations between methyl bromide and most cancers examined; however, there were small numbers of exposed cases for many sites. methyl bromide Workers United States Details Agricultural Workers' Diseases | Prostatic Neoplasms | Stomach Neoplasms
24. Hou L, et al. (2006). Agricultural Health Study (AHS) We did not find a clear association of lifetime pendimethalin exposure either with overall cancer incidence or with specific cancer sites. pendimethalin Workers United States Details Colorectal Neoplasms | Hematologic Neoplasms | Lymphoma, Non-Hodgkin | Melanoma | Neoplasms | Prostatic Neoplasms
25. Steenland K, et al. (2013). C8 Health Project (C8HP) We found evidence that perfluorooctanoic acid is associated with ulcerative colitis. perfluorooctanoic acid Study subjects | Workers United States serum perfluorooctanoic acid Details Colitis, Ulcerative
26. Rusiecki JA, et al. (2009). Agricultural Health Study (AHS) In this study we evaluated the incidence of cancer among pesticide applicators exposed to permethrin in the Agricultural Health Study (AHS). Permethrin Workers United States Details Colonic Neoplasms | Leukemia | Lung Neoplasms | Lymphoma, Non-Hodgkin | Melanoma | Multiple Myeloma | Neoplasms | Prostatic Neoplasms | Rectal Neoplasms
27. Hauser R, et al. (2004). National Health and Nutrition Examination Survey (NHANES) One potential source of phthalate exposure is medications, as the enteric coatings of certain drugs contain plasticizers; here, we report on medications as a potential source of exposure to dibutyl phthalate in a man who took Asacol for the treatment of ulcerative colitis. disease Phthalic Acids Subjects with disease:Colitis, Ulcerative | Study subjects United States urine mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate Details
28. Goto H, et al. (2012). Life Span Study We calculated the standardized mortality ratio (SMR) for the atomic bomb survivors versus the entire population of Japan in childhood and compared them with a true non-exposed group. A notable result was that SMRs in boys exposed to low doses were significantly higher for solid cancer. sex Radioactive Fallout Children Japan Radioactive Fallout Details Breast Neoplasms | Death | Leukemia | Liver Neoplasms | Neoplasms | Stomach Neoplasms | Uterine Neoplasms
29. Mozzachio AM, et al. (2008). Agricultural Health Study (AHS) Chlorothalonil was not associated with overall cancer incidence, nor did we find any association with colon, lung, and prostate cancers - the only cancers for which we had sufficient numbers to explore associations. tetrachloroisophthalonitrile Workers United States Details Colonic Neoplasms | Lung Neoplasms | Neoplasms | Prostatic Neoplasms
30. Rafiq R, et al. (2016). Our findings indicate increased risk of esophageal squamous cell carcinoma due to secondhand smoking exposure in dose-dependent manner. socioeconomic status | tobacco Tobacco Smoke Pollution Controls for disease:Esophageal Squamous Cell Carcinoma | Subjects with disease:Esophageal Squamous Cell Carcinoma India Details Esophageal Squamous Cell Carcinoma
31. Eaton JE, et al. (2015). PSC Resource of Genetic Risk, Environment and Synergy Studies (PROGRESS) We performed a large, prospective multicenter study with two key aims: (i) identify novel exposures associated with primary sclerosing cholangitis (PSC) among those with and without inflammatory bowel disease (IBD); (ii) validate or refute environmental exposures that could potentially be associated with PSC (regardless of IBD status) that have been described in previous studies. diet | disease | tobacco Tobacco Smoke Pollution Subjects with disease:Cholangitis, Sclerosing | Subjects with disease:Inflammatory Bowel Diseases Canada|United States Details Cholangitis, Sclerosing | Inflammatory Bowel Diseases
32. Kang D, et al. (2008). Agricultural Health Study (AHS) In this prospective evaluation of cancer risk, trifluralin was not associated with most cancers. There was some suggestion of a possible link between trifluralin exposure and colon cancer risk in humans, but the inconsistency by exposure level and small numbers of colon cancers indicate this could be a chance finding. Trifluralin Workers United States Details Colonic Neoplasms
33. Villanueva CM, et al. (2017). We did not find clear evidence of an association between detailed estimates of lifetime total trihalomethane exposure and colorectal cancer in our large case-control study population; negative associations with chloroform suggest differences among specific trihalomethanes. diet Trihalomethanes Controls for disease:Colorectal Neoplasms | Subjects with disease:Colorectal Neoplasms Italy|Spain water, tap Chloroform | Trihalomethanes Details Colorectal Neoplasms
34. Dorevitch S, et al. (2012). Chicago Health, Environmental Exposure, and Recreation Study Limited-contact recreation, both on effluent-dominated waters and on waters designated for general use, was associated with an elevated risk of gastrointestinal illness. Waste Water Study subjects United States Details Eye Diseases | Gastrointestinal Diseases
1–34 of 34 results.