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Disease Granulomatous Disease, Chronic

Name Granulomatous Disease, Chronic
Synonyms Autosomal Recessive Chronic Granulomatous Disease | Chronic Granulomatous Disease | Chronic Granulomatous Diseases | Disease, Chronic Granulomatous | Diseases, Chronic Granulomatous | Granulomatous Diseases, Chronic | X Linked Chronic Granulomatous Disease | X-Linked Chronic Granulomatous Disease
Definition A defect of leukocyte function in which phagocytic cells ingest but fail to digest bacteria, resulting in recurring bacterial infections with granuloma formation. When chronic granulomatous disease is caused by mutations in the CYBB gene, the condition is inherited in an X-linked recessive pattern. When chronic granulomatous disease is caused by CYBA, NCF1, NCF2, or NCF4 gene mutations, the condition is inherited in an autosomal recessive pattern.
Categories Blood disease | Genetic disease (inborn) | Immune system disease
MeSH® ID D006105
External Links

Top ↑ Ancestors

1. DiseasesHemic and Lymphatic Diseases Has associated chemicals Has associated genes Has associated exposure references Hematologic Diseases Has associated chemicals Has associated genes Has associated exposure references Leukocyte Disorders Has associated chemicals Has associated genes Phagocyte Bactericidal Dysfunction Has associated chemicals Has associated genes Granulomatous Disease, Chronic Has associated chemicals Has associated genes
2. DiseasesCongenital, Hereditary, and Neonatal Diseases and Abnormalities Has associated chemicals Has associated genes Has associated exposure references Genetic Diseases, Inborn Has associated chemicals Has associated genes Has associated exposure references Genetic Diseases, X-Linked Has associated chemicals Has associated genes Granulomatous Disease, Chronic Has associated chemicals Has associated genes
3. DiseasesImmune System Diseases Has associated chemicals Has associated genes Has associated exposure references Immunologic Deficiency Syndromes Has associated chemicals Has associated genes Phagocyte Bactericidal Dysfunction Has associated chemicals Has associated genes Granulomatous Disease, Chronic Has associated chemicals Has associated genes

Top ↑ Descendants

Granulomatous Disease, Chronic Has associated chemicals Has associated genes
  Combined Cellular And Humoral Immune Defects With Granulomas Has associated chemicals Has associated genes
  Granulomatous Disease, Chronic, Autosomal Dominant Type
  Granulomatous Disease, Chronic, Autosomal Recessive, Cytochrome B-Negative Has associated chemicals Has associated genes
  Granulomatous Disease, Chronic, Autosomal Recessive, Cytochrome B-Positive, Type I Has associated chemicals Has associated genes
  Granulomatous Disease, Chronic, Autosomal Recessive, Cytochrome B-Positive, Type II Has associated chemicals Has associated genes
  Granulomatous Disease, Chronic, X-Linked Has associated chemicals Has associated genes
  Granulomatous Disease with Defect in Neutrophil Chemotaxis