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Disease Heart Diseases

These are exposure studies associated with the disease and all of its children.

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1–50 of 57 results.
  Reference Associated Study Title Author's Summary Study Factors Stressor Receptors Country Medium Exposure Marker Measurements Outcome
1. Schreinemachers DM. (2010). National Health and Nutrition Examination Survey (NHANES) The results indicate that exposure to 2,4-dichlorophenoxyacetic acid was associated with changes in biomarkers that, based on the published literature, have been linked to risk factors for acute myocardial infarction and type 2 diabetes. 2,4-Dichlorophenoxyacetic Acid Study subjects United States urine 2,4-Dichlorophenoxyacetic Acid Details Diabetes Mellitus, Type 2 | Heart Diseases | cellular triglyceride homeostasis | glucose metabolic process | insulin metabolic process | thyroid-stimulating hormone secretion
2. Hansen AB, et al. (2016). Danish Nurse Cohort We examined the association between long-term exposure to particulate matter (PM2.5) and diabetes incidence; non-smokers, obese subjects, and cardiovascular disease patients may be most susceptible to development of diabetes related to air pollution. disease | tobacco Air Pollutants Subjects with disease:Diabetes Mellitus | Subjects with disease:Myocardial Infarction | Subjects with disease:Obesity | Study subjects Denmark air, ambient Nitrogen Dioxide | Nitrogen Oxides | Particulate Matter Details Diabetes Mellitus
3. López-Villarrubia E, et al. (2010). Our findings indicate the existence of a short-term association between current exposure levels to air pollutants and total mortality as well as mortality due to heart and respiratory diseases in both Canary cities studied along with evidence that the association on a given day may spread over several successive days. Air Pollutants Spain air Carbon Monoxide | Nitrogen Dioxide | Ozone | Particulate Matter | Sulfur Dioxide Details Death | Heart Diseases | Respiratory Tract Diseases
4. Symons JM, et al. (2006). The authors evaluated the association between particulate matter PM2.5 exposure and onset of congestive heart failure symptom exacerbation leading to hospital admission; although overall findings were not statistically significant, the identification of case events defined by an 8-hour onset period may be more relevant than either a 24-hour onset period or the admission date for estimating harmful effects. Air Pollutants Subjects with disease:Heart Failure United States air, ambient Carbon Monoxide | Nitrogen Dioxide | Ozone | Particulate Matter Details
5. Medina-Ramón M, et al. (2008). Worcester Heart Attack Study Residential exposure to traffic-related air pollution increases the mortality risk after hospitalization with acute heart failure. Air Pollutants Subjects with disease:Heart Failure United States Details Death
6. Brüske I, et al. (2011). Air Pollution and Inflammatory Response in Myocardial Infarction Survivors: Gene-Environment Interaction in a High Risk Group (AIRGENE) These preliminary findings should be replicated in other study populations because they suggest that the accumulation of acute and subacute effects or the chronic exposure to ambient particulate and gaseous air pollution may result in the promotion of atherosclerosis, mediated, at least in part, by increased levels of lipoprotein-associated phospholipase A2. Air Pollutants | Carbon Monoxide | Nitric Oxide | Nitrogen Dioxide | Ozone | Particulate Matter | Sulfur Dioxide Subjects with disease:Myocardial Infarction Germany air, ambient | plasma Carbon Monoxide | Nitric Oxide | Nitrogen Dioxide | Ozone | Particulate Matter | PLA2G7 | Sulfur Dioxide Details Atherosclerosis
7. Ljungman P, et al. (2009). Air Pollution and Inflammatory Response in Myocardial Infarction Survivors: Gene-Environment Interaction in a High Risk Group (AIRGENE) We found the interleukin-6 response to air pollution is modified by genetic polymorphisms in IL6 and FGB genes, suggesting the effect of gaseous traffic-related air pollution on inflammation may be stronger in genetic subpopulations with ischemic heart disease. disease | genetics Air Pollutants | Carbon Monoxide | Vehicle Emissions Subjects with gene influence:FGB | Subjects with gene influence:IL6 | Subjects with disease:Myocardial Infarction Finland|Germany|
Greece|Italy|
Spain|Sweden
air, ambient | plasma Carbon Monoxide | IL6 | Nitrogen Dioxide | Particulate Matter Details positive regulation of interleukin-6 production
8. Delfino RJ, et al. (2010). Traffic emission sources of organic chemicals represented by polycyclic aromatic hydrocarbons are associated with increased systemic inflammation and explain associations with quasi-ultrafine particle mass. Air Pollutants | hopane | Polycyclic Aromatic Hydrocarbons | Vehicle Emissions Subjects with disease:Coronary Artery Disease United States air, outdoor | plasma Alkanes | Chromium | Copper | hopane | IL6 | Iron | Manganese | Nickel | Particulate Matter | Polycyclic Aromatic Hydrocarbons | TNFRSF1B | Vanadium | Zinc Details
9. Levinsson A, et al. (2014). INTERGENE/ADONIX Air pollution exposure entails an increased risk of acute myocardial infarction, and this risk differed over genotype strata for variants in the GSTP1, GSTT1 and GSTCD genes, albeit not statistically-significantly. genetics Air Pollutants | Nitrogen Dioxide Subjects with gene influence:GSTP1 | Controls for disease:Myocardial Infarction | Subjects with disease:Myocardial Infarction Sweden Nitrogen Dioxide Details Hypertension | Myocardial Infarction
10. Hankey S, et al. (2012). Between-neighborhood differences in estimated ischemic heart disease mortality from air pollution were comparable in magnitude, suggesting that population health benefits from increased physical activity in high-walkability neighborhoods may be offset by adverse effects of air pollution exposure. physical activity Air Pollutants | Nitrogen Oxides | Ozone | Particulate Matter Study subjects United States air Nitrogen Dioxide | Nitrogen Oxides | Ozone | Particulate Matter Details Myocardial Ischemia
11. Liu CB, et al. (2016). Our findings suggest some positive associations between maternal exposure to ambient particulate matter (PM10) during the first two months of pregnancy and fetal cardiovascular malformations. Air Pollutants | Particulate Matter Infants or newborns | Pregnant females China air, ambient Particulate Matter Details Cardiovascular Abnormalities | Ductus Arteriosus, Patent | Heart Septal Defects, Atrial | Heart Septal Defects, Ventricular | Tetralogy of Fallot
12. Monrad M, et al. (2017). Danish Diet, Cancer, and Health cohort Study We found long-term residential traffic-related air pollution to be associated with higher risk of atrial fibrillation. Air Pollutants | Vehicle Emissions Study subjects Denmark air, ambient Nitrogen Dioxide | Nitrogen Oxides Details Atrial Fibrillation
13. Zhang W, et al. (1994). We report early health effects and biological monitoring in persons occupationally exposed to tetraethyl lead in China for the years 1990-1992, including for gasoline depot workers and traffic police officers. Air Pollutants, Occupational | Tetraethyl Lead Workers China air, ambient | urine diethyllead | Lead | triethyllead Details Bradycardia | Tremor
14. Yuan Y, et al. (2007). We conclude that the major impact of arsenic in drinking water on circulatory disease involves acute myocardial infarction and that, in the initial years, it is the main cause of death from arsenic in drinking water, superseded in later years by excess mortality from lung and bladder cancer. Arsenic Study subjects Chile water Arsenic Details Lung Neoplasms | Myocardial Infarction | Urinary Bladder Neoplasms
15. Cui N, et al. (2016). Long-term exposure to arsenic is associated with upregulated mRNA expression for genes AHR and CYP1A1 in the blood, and blood CYP1A1 mRNA (but not AHR mRNA) is associated with prolonged corrected QT interval. diet Arsenic Study subjects China blood | water, drinking AHR | Arsenic | CYP1A1 Details Long QT Syndrome | regulation of heart rate
16. Wade TJ, et al. (2009). This is the first study to document increased arsenic-associated mortality in the Bayingnormen Inner Mongolia region of China. Arsenic Study subjects China water Arsenic Details Coronary Disease | Death | Neoplasms
17. Zierold KM, et al. (2004). Respondents with arsenic levels of 2 microg/L or greater were statistically more likely to report a history of depression, high blood pressure, circulatory problems, and bypass surgery than were respondents with arsenic concentrations less than 2 microg/L. Arsenic Study subjects United States water Arsenic Details Depressive Disorder | Heart Diseases | Hypertension
18. Sanders AP, et al. (2014). In the present study we examined private well water levels of arsenic, cadmium, manganese, and lead across North Carolina, and used a semi-ecologic study design to estimate the association between metal levels and specific birth defect phenotypes. Arsenic | Cadmium | Lead | Manganese Infants or newborns United States Arsenic | Cadmium | Lead | Manganese Details Cleft Lip | Congenital Microtia | Conotruncal cardiac defects | Hypoplastic Left Heart Syndrome | Pyloric Stenosis
19. Thurston GD, et al. (2016). American Cancer Society Cancer Prevention Study II (ACS CPS-II) Long-term fine particulate matter (PM2.5) exposures from fossil fuel combustion, especially coal burning but also from diesel traffic, were associated with increases in ischemic heart disease mortality in this nationwide population. Arsenic | Carbon | Chlorine | Iron | Lead | Manganese | Particulate Matter | Potassium | Selenium | Silicon | Soot | Sulfur Study subjects United States air, ambient | soil Arsenic | Calcium | Carbon | Chlorine | Iron | Lead | Manganese | Nickel | Particulate Matter | Potassium | Selenium | Silicon | Sodium | Soot | Sulfur | Vanadium | Zinc Details Death | Myocardial Ischemia
20. Keil AP, et al. (2017). Lee-Fraumeni Cohort Our analyses suggest that the excess deaths from causes other than respiratory cancers comprise the majority of the excess deaths caused by inhaled arsenic exposure. arsenic trioxide Workers United States air arsenic trioxide Details Death | Heart Diseases | Respiratory Tract Neoplasms
21. Melzer D, et al. (2012). European Prospective Investigation into Cancer and Nutrition (EPIC) Study Associations between higher bisphenol A exposure (reflected in higher urinary concentrations) and incident coronary artery disease during >10 years of follow-up showed trends similar to previously reported cross-sectional findings in the more highly exposed NHANES respondents. bisphenol A Controls for disease:Coronary Artery Disease | Subjects with disease:Coronary Artery Disease United Kingdom urine bisphenol A Details Coronary Artery Disease
22. Melzer D, et al. (2010). National Health and Nutrition Examination Survey (NHANES) Higher Bisphenol A (BPA) exposure, reflected in higher urinary concentrations of BPA, is consistently associated with reported heart disease in the general adult population of the USA. bisphenol A Study subjects United States urine bisphenol A Details Angina Pectoris | Coronary Disease | Diabetes Mellitus | Myocardial Infarction | alkaline phosphatase activity | lactate dehydrogenase activity
23. LaKind JS, et al. (2012). National Health and Nutrition Examination Survey (NHANES) With scientifically and clinically supportable exclusion criteria and outcome definitions, we consistently found no associations between urinary bisphenol A and heart disease or diabetes across four NHANES datasets. bisphenol A Study subjects United States urine Details Diabetes Mellitus | Heart Diseases
24. Wright JM, et al. (2017). This is the first epidemiological study of birth defects and disinfection by-products (DBPs) to examine several individual cardiovascular defects, different exposure surrogate mixtures (sum of chloroform, bromoform, bromodichloromethane, and dibromochloromethane (THM4), brominated trihalomethanes, sum of monochloroacetic acid, dichloroacetic acid, trichloroacetic acid, monobromoacetic acid, and dibromoacetic acid (HAA5), sum of THM4 and HAA5, and various individual DBP species. sex bromoacetate | bromodichloromethane | bromoform | chloroacetic acid | chlorodibromomethane | Chloroform | dibromoacetic acid | Dichloroacetic Acid | Trichloroacetic Acid Fetuses | Pregnant females United States water, drinking Acetates | bromoacetate | bromodichloromethane | bromoform | chloroacetic acid | chlorodibromomethane | Chloroform | dibromoacetic acid | Dichloroacetic Acid | Trichloroacetic Acid | Trihalomethanes Details Cardiovascular Abnormalities | Heart Septal Defects, Atrial | Heart Septal Defects, Ventricular | Pulmonary Valve Stenosis | Tetralogy of Fallot | Transposition of Great Vessels
25. Peters JL, et al. (2010). National Health and Nutrition Examination Survey (NHANES) Environmental exposure to cadmium was associated with significantly increased stroke and heart failure prevalence. sex | tobacco Cadmium Study subjects United States blood | urine Cadmium Details Heart Failure | Stroke
26. Barregard L, et al. (2016). Malmo Diet and Cancer Study Blood cadmium in the highest quartile was associated with incident cardiovascular disease and mortality in our population-based samples of Swedish adults. tobacco Cadmium Study subjects Sweden blood Cadmium Details Cardiovascular Diseases | Myocardial Ischemia | Stroke
27. Dayton SB, et al. (2010). Agricultural Health Study (AHS) We investigated the relationship between agricultural pesticide use and the incidence of myocardial infarction among women in the Agricultural Health Study. Carbofuran | Chlorpyrifos | Coumaphos | metalaxyl | pendimethalin | Trifluralin Study subjects | Workers United States Details Agricultural Workers' Diseases | Myocardial Infarction
28. Suh HH, et al. (2010). Results indicate decreased vagal tone in response to traffic pollutants, which can best be detected with precise personal exposure measures. Carbon | Nitrogen Dioxide | Ozone | Particulate Matter | Sulfates Subjects with disease:Myocardial Infarction | Subjects with disease:Pulmonary Disease, Chronic Obstructive | Study subjects United States air Carbon | Nitrogen Dioxide | Ozone | Particulate Matter | Sulfates Details heart contraction
29. Ghosh R, et al. (2016). We investigated the coronary heart disease burden from near-roadway air pollution and compared it with the particulate matter <= 2.5 microns burden in the California South Coast Air Basin for 2008 and under a compact urban growth greenhouse gas reduction scenario for 2035. Carbon | Particulate Matter Study subjects United States Carbon | Particulate Matter Details Coronary Disease | Death
30. Berglind N, et al. (2010). Swedish Onset study This study provides no support that moderately elevated air pollution levels trigger first-time myocardial infarction. Carbon Monoxide | Nitrogen Dioxide | Ozone | Particulate Matter Subjects with disease:Myocardial Infarction Sweden air Carbon Monoxide | Nitrogen Dioxide | Ozone | Particulate Matter Details Myocardial Infarction
31. Milojevic A, et al. (2014). This study found no clear evidence for pollution effects on ST-elevation myocardial infarctions and stroke, which ultimately represent thrombogenic processes, though it did for pulmonary embolism. age | sex Carbon Monoxide | Nitrogen Dioxide | Ozone | Particulate Matter | Sulfur Dioxide Study subjects United Kingdom air, ambient Carbon Monoxide | Nitrogen Dioxide | Ozone | Particulate Matter | Sulfur Dioxide Details Arrhythmias, Cardiac | Atrial Fibrillation | Cardiovascular Diseases | Death | Stroke
32. Gilboa SM, et al. (2005). A population-based case-control study investigated the association between maternal exposure to air pollutants, carbon monoxide, nitrogen dioxide, ozone, sulfur dioxide, and particulate matter <10 microns in aerodynamic diameter during weeks 3-8 of pregnancy and the risk of selected cardiac birth defects and oral clefts in livebirths and fetal deaths between 1997 and 2000 in seven Texas counties. sex Carbon Monoxide | Nitrogen Dioxide | Ozone | Particulate Matter | Sulfur Dioxide Children United States Details Cleft Lip | Cleft Palate | Conotruncal cardiac defects | Endocardial Cushion Defects | Heart Septal Defects, Atrial | Heart Septal Defects, Ventricular | Tetralogy of Fallot
33. Koken PJ, et al. (2003). In summary, the results of this study in Denver suggest that ozone increases the risk of hospitalization for acute myocardial infarction, coronary atherosclerosis, and pulmonary heart disease. Sulfur dioxide appears to be related to increased hospital stays for cardiac dysrhythmias, and carbon monoxide is significantly associated with congestive heart failure hospitalization. sex Carbon Monoxide | Nitrogen Dioxide | Ozone | Particulate Matter | Sulfur Dioxide Study subjects United States air Carbon Monoxide | Nitrogen Dioxide | Ozone | Sulfur Dioxide Details Arrhythmias, Cardiac | Atherosclerosis | Heart Failure | Myocardial Infarction | Pulmonary Heart Disease
34. Kim C, et al. (2016). Shanghai Women's Health Study (SWHS) Evidence from this study suggests that past use of coal among women in Shanghai is associated with excess all-cause mortality and from cardiovascular diseases in particular. Coal Study subjects China Details Cardiovascular Diseases | Death | Myocardial Infarction | Neoplasms
35. Lagat DK, et al. (2014). In this pilot study among women of western Kenya, lower kitchen ventilation, airflow limitation, HIV, and occupational dust exposure were associated with isolated right heart failure, overall or in participant subgroups; direct or indirect causality requires further study. Dust Controls for disease:Heart Failure | Subjects with disease:Heart Failure Kenya Details Heart Failure
36. Amin R, et al. (2017). We find that gadolinium use during pregnancy is unlikely to be associated with adverse effects in infants during the neonatal period. Gadolinium Infants or newborns | Pregnant females United States blood, cord Gadolinium Details Birth Weight | Bone Diseases, Metabolic | Chorioamnionitis | Diabetes, Gestational | Ductus Arteriosus, Patent | Enterocolitis, Necrotizing | Fetal Growth Retardation | Hyperbilirubinemia, Neonatal | Hypertension, Pregnancy-Induced | Lung Diseases | Obstetric Labor, Premature | Oligohydramnios | Prenatal Exposure Delayed Effects | Respiratory Distress Syndrome, Newborn | Retinopathy of Prematurity
37. Gensburg LJ, et al. (2009). The aim of this study was to describe the mortality experience of the former Love Canal residents from the years 1979-1996. Hazardous Waste Study subjects United States Details Myocardial Infarction
38. Khalil N, et al. (2009). Study of Osteoporotic Fractures (SOF) Women with blood lead concentrations of > or = 8 microg/dL (0.384 micromol/L), experienced increased mortality, in particular from coronary heart disease as compared to those with lower blood lead concentrations. age | tobacco Lead Study subjects United States blood Lead Details Coronary Disease | Death
39. Hunt A, et al. (2003). We have located and analyzed rare archival tissue samples that provide otherwise unavailable clues to the nature of the fatal PM exposures in the 1952 London smog. Metals, Heavy | Particulate Matter | Smog Study subjects United Kingdom Details Death | Heart Diseases | Pulmonary Disease, Chronic Obstructive | Respiratory Tract Diseases
40. Gan WQ, et al. (2011). This large, population-based cohort study demonstrated that long-term exposure to higher concentrations of black carbon was associated with an increased risk of coronary heart disease hospitalization and mortality in an exposure-response fashion. Nitric Oxide | Nitrogen Dioxide | Particulate Matter | Soot Study subjects Canada air Nitric Oxide | Nitrogen Dioxide | Particulate Matter | Soot Details Coronary Disease
41. Tonne C, et al. (2009). Worcester Heart Attack Study These results provide some support for an association between long-term exposure to traffic particles and risk of acute myocardial infarction. Nitrogen Dioxide | Particulate Matter | Vehicle Emissions Study subjects United States air Nitrogen Dioxide | Particulate Matter | Vehicle Emissions Details Myocardial Infarction
42. Hoffmann B, et al. (2009). German Heinz Nixdorf Recall Study Our study indicates that long-term residential exposure to high levels of Particulate Matter (2.5) is associated with systemic inflammatory markers in men. sex Ozone | Particulate Matter Controls for disease:Coronary Disease | Subjects with disease:Coronary Disease | Controls for disease:Diabetes Mellitus | Subjects with disease:Diabetes Mellitus | Study subjects Germany air CRP | Ozone | Particulate Matter Details Atherosclerosis | Inflammation
43. Chen LH, et al. (2005). Adventist Health Study on the Health Effects of Smog (AHSMOG) In summary, in this study we found an elevated risk of fatal coronary heart disease associated with ambient levels of particulate matter (PM)10, PM10-2.5, and PM2.5 in females but not in males. Ozone | Particulate Matter Study subjects United States Details Coronary Disease
44. Claeys MJ, et al. (2015). In a global environmental model, low temperature is the most important environmental trigger for ST-elevation myocardial infarction, whereas air pollution and influenza epidemics only seem to have a modest effect. disease Ozone | Particulate Matter | Smoke Subjects with disease:Myocardial Infarction Belgium air Ozone | Particulate Matter | Smoke Details Myocardial Infarction
45. Puett RC, et al. (2008). Nurses' Health Study (NHS) In a population of women residing in Metropolitan Statistical Areas in the northeastern region of the United States, all-cause mortality was statistically significantly associated with average particulate matter less than 10 microns in diameter exposures in the time period 3-48 months prior to death. body mass index | tobacco Particulate Matter Workers United States Particulate Matter Details Coronary Disease | Death
46. Zhang ZM, et al. (2009). Environmental Epidemiology of Arrhythmogenesis in Women's Health Initiative (EEAWHI) Short-term Particulate Matter (aerodynamic size <=2.5 microns) exposure is associated with electrocardiogram evidence of myocardial ischemia among postmenopausal women. sex Particulate Matter Study subjects United States air Particulate Matter Details Arrhythmias, Cardiac | Myocardial Ischemia
47. Chen H, et al. (2016). Enhanced Feedback For Effective Cardiac Treatment (EFFECT) Study Long-term air pollution exposure adversely affects the survival of acute myocardial infarction patients. Particulate Matter Subjects with disease:Myocardial Infarction Canada air Particulate Matter Details Death
48. He F, et al. (2010). Air Pollution and Cardiac Risk and its Time Course (APACR) Study In summary, acute exposure to Particulate Matter (PM2.5) at the individual level, is directly associated with higher ST-segment height measures in inferior and lateral leads, which is indicative of regional ischemic damage potential to the myocardium. Particulate Matter Study subjects United States air Particulate Matter Details Myocardial Ischemia
49. Orru H, et al. (2009). Respiratory Health in Northern Europe (RHINE) cohort In this study in Tartu a strong relation between exhaust traffic particles and cardiac diseases was established. Particulate Matter Study subjects Estonia Vehicle Emissions Details Heart Diseases
50. Siponen T, et al. (2015). Results suggest that particulate matter (2.5) from several sources, such as biomass combustion and traffic, are promoters of systemic inflammation, a risk factor for cardiovascular diseases. Particulate Matter Subjects with disease:Myocardial Ischemia Finland air Particulate Matter Details Cardiovascular Diseases | Inflammation | inflammatory response
1–50 of 57 results.