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Disease Heart Septal Defects

These phenotypes are associated with Heart Septal Defects or its descendants. A phenotype has an inferred association via a curated chemical interaction or a gene-GO annotation or both.

1–50 of 3,741 results.
  Phenotype Disease Chemical Inference Network Gene Inference Network References
1. apoptotic process Heart Septal Defects, Ventricular Inferred via 23 chemicals: Acetazolamide | Air Pollutants | Aspirin | Buthionine Sulfoximine | Caffeine | Cocaine | Diethylstilbestrol | Ethanol | Ethinyl Estradiol | Homocysteine | Ibuprofen | Leflunomide | Medroxyprogesterone Acetate | Nitrogen Dioxide | Norethindrone | Ozone | Particulate Matter | Phenobarbital | Phenytoin | Progesterone | Thalidomide | Tocopherols | Valproic Acid Inferred via 1 gene: EPO 232
2. cell proliferation Heart Septal Defects, Ventricular Inferred via 22 chemicals: Aspirin | bromoacetate | Buthionine Sulfoximine | Caffeine | Cocaine | Diethylstilbestrol | Ethanol | Ethinyl Estradiol | Homocysteine | Ibuprofen | Leflunomide | Medroxyprogesterone Acetate | Nandrolone | Norethindrone | Norethynodrel | Ozone | Particulate Matter | Phenobarbital | Phenytoin | Progesterone | Thalidomide | Valproic Acid Inferred via 2 genes: CITED2 | EPO 173
3. cell death Heart Septal Defects, Ventricular Inferred via 21 chemicals: Aspirin | Buthionine Sulfoximine | Caffeine | Carbamazepine | Cocaine | Ethanol | Ethinyl Estradiol | Homocysteine | Ibuprofen | Leflunomide | Nitrogen Dioxide | Norethindrone | Norethynodrel | Ozone | Particulate Matter | Phenobarbital | Phenytoin | Progesterone | Thalidomide | Tocopherols | Valproic Acid   93
4. response to oxidative stress Heart Septal Defects, Ventricular Inferred via 16 chemicals: Air Pollutants | Aspirin | Buthionine Sulfoximine | Caffeine | Cocaine | Ethanol | Homocysteine | Nitrogen Dioxide | Ozone | Particulate Matter | Phenobarbital | Progesterone | Sulfur Dioxide | Thalidomide | Tocopherols | Valproic Acid   66
5. regulation of blood pressure Heart Septal Defects, Ventricular Inferred via 15 chemicals: Air Pollutants | Aspirin | Buthionine Sulfoximine | Caffeine | Cocaine | Diethylstilbestrol | Dimethadione | Ethanol | Ethinyl Estradiol | Ibuprofen | Nitrogen Dioxide | Ozone | Particulate Matter | Phenobarbital | Valproic Acid   118
6. positive regulation of cell death Heart Septal Defects, Ventricular Inferred via 13 chemicals: Aspirin | Buthionine Sulfoximine | Caffeine | Carbamazepine | Ethanol | Ethinyl Estradiol | Ibuprofen | Leflunomide | Particulate Matter | Phenobarbital | Phenytoin | Thalidomide | Valproic Acid   56
7. DNA damage response, detection of DNA damage Heart Septal Defects, Ventricular Inferred via 12 chemicals: Air Pollutants | bromoacetate | Buthionine Sulfoximine | Cocaine | Diethylstilbestrol | Ethanol | Ozone | Particulate Matter | Phenobarbital | Phenytoin | Thalidomide | Valproic Acid   58
8. apoptotic DNA fragmentation Heart Septal Defects, Ventricular Inferred via 12 chemicals: Aspirin | Buthionine Sulfoximine | Caffeine | Cocaine | Ethanol | Homocysteine | Ibuprofen | Medroxyprogesterone Acetate | Particulate Matter | Phenobarbital | Thalidomide | Valproic Acid   47
9. regulation of heart rate Heart Septal Defects, Ventricular Inferred via 11 chemicals: Air Pollutants | Caffeine | Cocaine | Ethanol | Ibuprofen | Nitrogen Dioxide | Ozone | Particulate Matter | Phenobarbital | Sulfur Dioxide | Thalidomide   65
10. membrane lipid catabolic process Heart Septal Defects, Ventricular Inferred via 11 chemicals: Aspirin | Buthionine Sulfoximine | Cocaine | Diethylstilbestrol | Ethanol | Ibuprofen | Nitrogen Dioxide | Ozone | Phenobarbital | Thalidomide | Tocopherols   45
11. cell proliferation Heart Septal Defects, Atrial Inferred via 11 chemicals: Carbon Monoxide | Cocaine | Diethylstilbestrol | Epoprostenol | Ethanol | Homocysteine | Paroxetine | Particulate Matter | Phenobarbital | Phenytoin | Valproic Acid   97
12. apoptotic process Heart Septal Defects, Atrial Inferred via 11 chemicals: Air Pollutants | Carbon Monoxide | Cocaine | Diethylstilbestrol | Ethanol | Homocysteine | Paroxetine | Particulate Matter | Phenobarbital | Phenytoin | Valproic Acid   102
13. cell differentiation Heart Septal Defects, Ventricular Inferred via 10 chemicals: Aspirin | Cocaine | Diethylstilbestrol | Ethanol | Homocysteine | Medroxyprogesterone Acetate | Norethindrone | Progesterone | Thalidomide | Valproic Acid Inferred via 2 genes: CITED2 | NKX2-5 24
14. regulation of blood pressure Heart Septal Defects, Atrial Inferred via 10 chemicals: Air Pollutants | Carbon Monoxide | Cocaine | Diethylstilbestrol | Epoprostenol | Ethanol | Particulate Matter | Phenobarbital | Ritodrine | Valproic Acid Inferred via 1 gene: MYH6 70
15. reactive oxygen species biosynthetic process Heart Septal Defects, Ventricular Inferred via 10 chemicals: Air Pollutants | Buthionine Sulfoximine | Cocaine | Ethanol | Ethinyl Estradiol | Leflunomide | Ozone | Particulate Matter | Thalidomide | Valproic Acid   48
16. positive regulation of cell proliferation Heart Septal Defects, Ventricular Inferred via 9 chemicals: Aspirin | Diethylstilbestrol | Ethanol | Ethinyl Estradiol | Nandrolone | Particulate Matter | Phenobarbital | Progesterone | Valproic Acid Inferred via 2 genes: EPO | NKX2-5 23
17. regulation of heart rate Heart Septal Defects, Atrial Inferred via 9 chemicals: Air Pollutants | Carbon Monoxide | Cocaine | Ethanol | Paroxetine | Particulate Matter | Phenobarbital | Ritodrine | Sulfur Dioxide Inferred via 1 gene: MYH6 58
18. cell cycle Heart Septal Defects, Ventricular Inferred via 9 chemicals: Aspirin | Caffeine | Cocaine | Diethylstilbestrol | Homocysteine | Ibuprofen | Leflunomide | Thalidomide | Valproic Acid   57
19. lipid catabolic process Heart Septal Defects, Ventricular Inferred via 9 chemicals: Aspirin | Caffeine | Cocaine | Ethanol | Ethinyl Estradiol | Particulate Matter | Phenobarbital | Progesterone | Sulfur Dioxide   55
20. lipid oxidation Heart Septal Defects, Ventricular Inferred via 9 chemicals: Air Pollutants | Aspirin | Buthionine Sulfoximine | Carbamazepine | Ethanol | Ibuprofen | Ozone | Particulate Matter | Thalidomide   28
21. vasoconstriction Heart Septal Defects, Ventricular Inferred via 9 chemicals: Acetazolamide | Aspirin | Buthionine Sulfoximine | Caffeine | Cocaine | Ethanol | Ibuprofen | Particulate Matter | Progesterone   54
22. response to oxidative stress Heart Septal Defects, Atrial Inferred via 9 chemicals: Air Pollutants | Cocaine | Ethanol | Homocysteine | Nitrofurantoin | Particulate Matter | Phenobarbital | Sulfur Dioxide | Valproic Acid   39
23. cell death Heart Septal Defects, Atrial Inferred via 9 chemicals: Carbamazepine | Cocaine | Epoprostenol | Ethanol | Homocysteine | Particulate Matter | Phenobarbital | Phenytoin | Valproic Acid   41
24. regulation of mitochondrial membrane potential Heart Septal Defects, Ventricular Inferred via 9 chemicals: Aspirin | Buthionine Sulfoximine | Caffeine | Cocaine | Ethanol | Particulate Matter | Phenobarbital | Phenytoin | Valproic Acid   36
25. DNA damage response, detection of DNA damage Heart Septal Defects, Atrial Inferred via 8 chemicals: Air Pollutants | Cocaine | Diethylstilbestrol | Ethanol | Particulate Matter | Phenobarbital | Phenytoin | Valproic Acid   49
26. vasodilation Heart Septal Defects, Ventricular Inferred via 8 chemicals: Acetazolamide | Aspirin | Caffeine | Cocaine | Ethanol | Ibuprofen | Particulate Matter | Progesterone   39
27. detection of oxidative stress Heart Septal Defects, Ventricular Inferred via 8 chemicals: Carbamazepine | chlorodibromomethane | Ethanol | Ethinyl Estradiol | Particulate Matter | Phenobarbital | Phenytoin | Valproic Acid   18
28. positive regulation of apoptotic process Heart Septal Defects, Ventricular Inferred via 8 chemicals: Aspirin | Buthionine Sulfoximine | Carbamazepine | Ethanol | Ibuprofen | Particulate Matter | Progesterone | Valproic Acid   34
29. spermatogenesis Heart Septal Defects, Ventricular Inferred via 7 chemicals: Cocaine | Diethylstilbestrol | Ethanol | Medroxyprogesterone | Medroxyprogesterone Acetate | Norethindrone | Progesterone Inferred via 1 gene: GATA4 12
30. positive regulation of reactive oxygen species biosynthetic process Heart Septal Defects, Ventricular Inferred via 7 chemicals: Air Pollutants | Buthionine Sulfoximine | Ethanol | Ibuprofen | Ozone | Particulate Matter | Valproic Acid   29
31. regulation of mitochondrial membrane potential Heart Septal Defects, Atrial Inferred via 7 chemicals: Carbon Monoxide | Cocaine | Ethanol | Particulate Matter | Phenobarbital | Phenytoin | Valproic Acid   22
32. DNA methylation Heart Septal Defects, Atrial Inferred via 7 chemicals: Air Pollutants | Carbon Monoxide | Cocaine | Homocysteine | Particulate Matter | Phenobarbital | Valproic Acid   16
33. positive regulation of cell death Heart Septal Defects, Atrial Inferred via 7 chemicals: Carbamazepine | Ethanol | Paroxetine | Particulate Matter | Phenobarbital | Phenytoin | Valproic Acid   33
34. cell growth Heart Septal Defects, Ventricular Inferred via 7 chemicals: Buthionine Sulfoximine | Carbamazepine | Cocaine | Ethanol | Ethinyl Estradiol | Particulate Matter | Valproic Acid   23
35. glutathione peroxidase activity Heart Septal Defects, Ventricular Inferred via 7 chemicals: Buthionine Sulfoximine | Caffeine | Ethanol | Ozone | Particulate Matter | Phenobarbital | Sulfur Dioxide   21
36. glutathione biosynthetic process Heart Septal Defects, Ventricular Inferred via 7 chemicals: Buthionine Sulfoximine | Caffeine | Ethanol | Ozone | Particulate Matter | Phenobarbital | Phenytoin   61
37. glutathione metabolic process Heart Septal Defects, Ventricular Inferred via 7 chemicals: Aspirin | Buthionine Sulfoximine | Carbamazepine | Ethanol | Ibuprofen | Particulate Matter | Valproic Acid   25
38. positive regulation of protein import into nucleus Heart Septal Defects, Ventricular Inferred via 7 chemicals: Aspirin | Diethylstilbestrol | Ibuprofen | Particulate Matter | Phenobarbital | Thalidomide | Valproic Acid   14
39. DNA methylation Heart Septal Defects, Ventricular Inferred via 7 chemicals: Air Pollutants | Cocaine | Homocysteine | Ozone | Particulate Matter | Phenobarbital | Valproic Acid   18
40. detection of oxidative stress Heart Septal Defects, Atrial Inferred via 7 chemicals: Carbamazepine | chlorodibromomethane | Ethanol | Particulate Matter | Phenobarbital | Phenytoin | Valproic Acid   17
41. lipid biosynthetic process Heart Septal Defects, Ventricular Inferred via 6 chemicals: Aspirin | Buthionine Sulfoximine | Caffeine | Ethanol | Progesterone | Valproic Acid   22
42. reactive oxygen species metabolic process Heart Septal Defects, Ventricular Inferred via 6 chemicals: Buthionine Sulfoximine | Diethylstilbestrol | Ethanol | Particulate Matter | Phenobarbital | Phenytoin   27
43. vasoconstriction Heart Septal Defects, Atrial Inferred via 6 chemicals: Carbon Monoxide | Cocaine | Epoprostenol | Ethanol | Particulate Matter | Ritodrine   41
44. mitotic cell cycle arrest Heart Septal Defects, Ventricular Inferred via 6 chemicals: Air Pollutants | Buthionine Sulfoximine | Ethanol | Nitrogen Dioxide | Particulate Matter | Valproic Acid   17
45. superoxide dismutase activity Heart Septal Defects, Ventricular Inferred via 6 chemicals: Cocaine | Ethanol | Ozone | Particulate Matter | Phenobarbital | Sulfur Dioxide   29
46. cell migration Heart Septal Defects, Ventricular Inferred via 6 chemicals: Carbamazepine | Ethanol | Particulate Matter | Phenytoin | Progesterone | Valproic Acid   14
47. leukocyte migration involved in inflammatory response Heart Septal Defects, Ventricular Inferred via 6 chemicals: Caffeine | Ethanol | Nitrogen Dioxide | Ozone | Particulate Matter | Sulfur Dioxide   31
48. mitotic cell cycle Heart Septal Defects, Ventricular Inferred via 6 chemicals: Caffeine | Ibuprofen | Medroxyprogesterone Acetate | Norethindrone | Progesterone | Thalidomide   10
49. apoptotic DNA fragmentation Heart Septal Defects, Atrial Inferred via 6 chemicals: Cocaine | Ethanol | Homocysteine | Particulate Matter | Phenobarbital | Valproic Acid   23
50. ATP biosynthetic process Heart Septal Defects, Ventricular Inferred via 6 chemicals: Buthionine Sulfoximine | Caffeine | Diethylstilbestrol | Ethanol | Leflunomide | Valproic Acid   14
1–50 of 3,741 results.