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Disease Hepatomegaly

These phenotypes are associated with Hepatomegaly or its descendants. A phenotype has an inferred association via a curated chemical interaction or a gene-GO annotation or both.

1–50 of 3,655 results.
  Phenotype Disease Chemical Inference Network Gene Inference Network References
1. cell proliferation Hepatomegaly Inferred via 192 chemicals: 1,2-dibromo-4-(1,2-dibromoethyl)cyclohexane | 1,2-Dimethylhydrazine | 1,3-dichloro-2-propanol | 1,4-bis(2-(3,5-dichloropyridyloxy))benzene | 1-Naphthylisothiocyanate | 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,4-Dinitrophenol | 2-Acetylaminofluorene | 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide | 3,4,5,3',4'-pentachlorobiphenyl | Acetaminophen | Acetylcysteine | ado-trastuzumab emtansine | Aflatoxin B1 | alpha-naphthoflavone | Amikacin | Amiloride | Amiodarone | Amitriptyline | Arsenic | Aspirin | benoxaprofen | Benzbromarone | beta-Naphthoflavone | Bilirubin | bisphenol A | Butylated Hydroxyanisole | Butylated Hydroxytoluene | Cadmium Chloride | Caffeine | Carbon Tetrachloride | Chlordecone | Chlorodiphenyl (54% Chlorine) | chlorpyrifos-methyl | Cholesterol | chrysin | ciprofibrate | Ciprofloxacin | Clofibrate | Clomiphene | Clonazepam | Clozapine | cocoa butter | Curcumin | Cyclophosphamide | cyproconazole | Dactinomycin | Dantrolene | DDT | decabromobiphenyl ether | Dexamethasone | Diazepam | dichlorfop-methyl | Dichloroacetic Acid | Dichlorodiphenyl Dichloroethylene | Diclofenac | Dietary Fats | Diethylhexyl Phthalate | Diethylnitrosamine | diethyl phthalate | Diethylstilbestrol | Diltiazem | Diosmin | Disulfiram | Doxorubicin | Enalapril | Endosulfan | enilconazole | esculetin | Ethanol | Ethinyl Estradiol | ethyl tert-butyl ether | fenarimol | Fenbendazole | fenvalerate | Fish Oils | Flame Retardants | Fluoxetine | Flutamide | Fluvastatin | Fructose | fumonisin B1 | furan | Galactosamine | gardenin A | geldanamycin | Genistein | Glutathione | Griseofulvin | GW0742 | Halogenated Diphenyl Ethers | Hexachlorobenzene | Hydrocarbons, Chlorinated | Imipramine | indole-3-carbinol | Iron | Isoflurane | Ketoconazole | lead nitrate | lipopolysaccharide, E coli O55-B5 | Lipopolysaccharides | Lovastatin | Luteolin | Malathion | Mequindox | Metformin | Methapyrilene | Methimazole | Methionine | Methotrexate | Methoxychlor | Methylnitrosourea | metolachlor | Mifepristone | Minocycline | Mycophenolic Acid | myricitrin | N-(2-(3-chloro-5-(trifluoromethyl)-2-pyridyl)ethyl)-alpha,alpha,alpha-trifluoro-o-toluamide | naphthalene | Nelfinavir | Nevirapine | nimesulide | nitrapyrin | nitrofen | Oligopeptides | Omeprazole | oxadiazon | Oxaliplatin | Papaverine | PCB 180 | perfluorohexanesulfonic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | Phenobarbital | Phenylbutazone | Phenytoin | piperine | Piperonyl Butoxide | pirinixic acid | Plant Extracts | Plant Preparations | Prednisolone | Pregnenolone Carbonitrile | propiconazole | Propranolol | Propylthiouracil | Pyrazinamide | pyrene | Quercetin | quercetin 3-O-glucuronide | Quinidine | Resveratrol | Riboflavin | Rifampin | Ritonavir | Rosiglitazone | Rutin | S-Adenosylmethionine | salvianolic acid B | Saponins | Sevoflurane | Sildenafil Citrate | Silymarin | Simvastatin | sodium arsenite | Sodium Cholate | Streptozocin | Sulfasalazine | Sulindac | Tamoxifen | tetrabromobisphenol A | Tetrachlorodibenzodioxin | Tetracycline | Thioacetamide | thymoquinone | Tolbutamide | Topiramate | Tretinoin | Trichloroethylene | tris(1,3-dichloro-2-propyl)phosphate | tris(chloroethyl)phosphate | ursolic acid | Valproic Acid | Verapamil | Verteporfin | Vincristine | Vitamin A | zileuton | Zinc Inferred via 2 genes: CYP1A1 | TGFB1 1372
2. apoptotic process Hepatomegaly Inferred via 157 chemicals: 1,2-Dimethylhydrazine | 1,3-dichloro-2-propanol | 2,2',4,4'-tetrabromodiphenyl ether | 2,4,5,2',4',5'-hexachlorobiphenyl | 2-Acetylaminofluorene | 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide | Acetaminophen | Acetylcysteine | Aflatoxin B1 | alpha-naphthoflavone | Amikacin | Amiloride | Amiodarone | Amitriptyline | Arsenic | Aspirin | beta-Naphthoflavone | Bezafibrate | Bilirubin | bisphenol A | brucine | Butylated Hydroxyanisole | Butylated Hydroxytoluene | Cadmium Chloride | Caffeine | Carbon Tetrachloride | Chloramphenicol | Chlorpheniramine | Cholesterol | Choline | chrysin | Ciprofloxacin | Clofibrate | Clomiphene | Clozapine | Curcumin | Cyclophosphamide | Dactinomycin | Danazol | Dantrolene | DDT | decabromobiphenyl ether | Dexamethasone | Diazepam | Dichlorodiphenyl Dichloroethylene | Diclofenac | Dietary Fats | Diethylhexyl Phthalate | Diethylnitrosamine | Diethylstilbestrol | Diltiazem | Diosmin | Disulfiram | Doxorubicin | Enalapril | Endosulfan | esculetin | Ethanol | Ethinyl Estradiol | ethyl tert-butyl ether | Fenofibrate | Fish Oils | Fluoxetine | Flutamide | formylchromone | Fructose | fumonisin B1 | Galactosamine | geldanamycin | Genistein | Glutathione | Hexachlorobenzene | Imipramine | indole-3-carbinol | Iron | Isoflurane | Isoniazid | Ketoconazole | lead nitrate | lipopolysaccharide, E coli O55-B5 | Lipopolysaccharides | Lovastatin | Luteolin | Malathion | Malondialdehyde | Metformin | Methapyrilene | Methimazole | Methionine | Methotrexate | methyleugenol | Methylnitrosourea | Mifepristone | Minocycline | Mycophenolic Acid | Nelfinavir | nimesulide | nitrofen | obeticholic acid | Oligopeptides | Omeprazole | Orotic Acid | Oxaliplatin | Papaverine | perfluorooctane sulfonic acid | perfluorooctanoic acid | Phenobarbital | Phenytoin | pirinixic acid | Plant Extracts | Plant Preparations | Prednisolone | Propofol | Propranolol | Propylthiouracil | Pyrazinamide | Quercetin | quercetin 3-O-glucuronide | Quinidine | Resveratrol | Riboflavin | Rifampin | Ritonavir | Rosiglitazone | Rutin | S-Adenosylmethionine | salvianolic acid B | Saponins | Sevoflurane | Sildenafil Citrate | Silymarin | Simvastatin | sodium arsenite | Stavudine | Streptozocin | Sulfasalazine | Sulindac | Tamoxifen | tetrabromobisphenol A | Tetrachlorodibenzodioxin | Thiamethoxam | Thioacetamide | thymoquinone | Ticlopidine | Tocopherols | Tolbutamide | Tretinoin | tris(1,3-dichloro-2-propyl)phosphate | troxerutin | ursolic acid | Valproic Acid | Verapamil | Vincristine | Vitamin A | Zidovudine | zileuton | Zinc Inferred via 5 genes: AHR | ATG5 | DAPK2 | KLF11 | MAPK14 1652
3. cell death Hepatomegaly Inferred via 134 chemicals: 1-Naphthylisothiocyanate | 2,2',4,4'-tetrabromodiphenyl ether | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,4-Dinitrophenol | Acetaminophen | Acetylcysteine | Aflatoxin B1 | alpha-naphthoflavone | Amiodarone | Amitriptyline | Aspirin | Azathioprine | Bezafibrate | bisphenol A | brucine | Butylated Hydroxyanisole | Cadmium Chloride | Caffeine | Carbamazepine | Carbon Tetrachloride | Chloramphenicol | Chlordan | Cholesterol | chrysin | Clonazepam | Clozapine | Curcumin | Dactinomycin | Dantrolene | decabromobiphenyl ether | Dexamethasone | Diazepam | Dichloroacetic Acid | Diclofenac | Dietary Fats | Diltiazem | Disulfiram | Doxorubicin | Enalapril | Endosulfan | epoxiconazole | Ethanol | Ethinyl Estradiol | fenvalerate | fipronil | Flame Retardants | Fluoxetine | Flutamide | Fluvastatin | fumonisin B1 | Galactosamine | gardenin A | geldanamycin | Gemfibrozil | Genistein | Glutathione | Griseofulvin | Halogenated Diphenyl Ethers | Hexachlorobenzene | Imipramine | Iron | Isoflurane | Isoniazid | Ketoconazole | lipopolysaccharide, E coli O55-B5 | Lipopolysaccharides | Lovastatin | Metformin | Methapyrilene | Methimazole | Methionine | Methotrexate | Methoxychlor | Methyldopa | Mifepristone | Minocycline | Mycophenolic Acid | myricitrin | naphthalene | Nelfinavir | nimesulide | oleuropein | Omeprazole | Oxaliplatin | Papaverine | perfluorohexanesulfonic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | Phenobarbital | Phenytoin | pirinixic acid | Plant Extracts | Probucol | Propranolol | Quercetin | Quinidine | Resveratrol | retrorsine | Rifampin | Ritonavir | Rosiglitazone | Rutin | salvianolic acid B | Saponins | Sevoflurane | Simvastatin | sodium arsenite | Streptozocin | Sulindac | Tamoxifen | tetrabromobisphenol A | Tetrachlorodibenzodioxin | Tetracycline | Thiamethoxam | Thioacetamide | thymoquinone | Tocopherols | Tolbutamide | Topiramate | Tretinoin | Triamcinolone Acetonide | Trichloroacetic Acid | Trichloroethylene | Trinitrotoluene | tris(1,3-dichloro-2-propyl)phosphate | tris(chloroethyl)phosphate | ursolic acid | Valproic Acid | Verapamil | Vincristine | Vitamin A | Zidovudine | Zinc   684
4. lipid catabolic process Hepatomegaly Inferred via 109 chemicals: 1,2-Dimethylhydrazine | 2,2',4,4'-tetrabromodiphenyl ether | 3,4,5,3',4'-pentachlorobiphenyl | Acetaminophen | Acetylcysteine | Aflatoxin B1 | Amiodarone | Arsenic | Aspirin | Bilirubin | bisphenol A | bromobenzene | Butylated Hydroxytoluene | Cadmium Chloride | Caffeine | Carbon Tetrachloride | Chitosan | Chlorodiphenyl (54% Chlorine) | Cholesterol | Cholesterol, Dietary | Choline | chrysin | Ciprofloxacin | Clofibrate | Curcumin | Cyclophosphamide | decabromobiphenyl ether | Dexamethasone | Diazepam | Dichloroacetic Acid | Dichlorodiphenyl Dichloroethylene | Diclofenac | Dietary Carbohydrates | Dietary Fats | Dietary Sucrose | Diethylhexyl Phthalate | Diethylnitrosamine | Doxorubicin | Enalapril | Endosulfan | esculetin | Ethambutol | Ethanol | Ethinyl Estradiol | fipronil | Fructose | fumonisin B1 | Galactosamine | gastrodin | Gemfibrozil | Genistein | Glutathione | Griseofulvin | Hexachlorobenzene | indole-3-carbinol | Iron | Iron-Dextran Complex | Isoniazid | lead chloride | lipopolysaccharide, E coli O55-B5 | Lipopolysaccharides | Lovastatin | Luteolin | Malathion | Mequindox | Metformin | Methiocarb | Methionine | Methotrexate | Mifepristone | Minocycline | myricitrin | Nelfinavir | oleuropein | Omeprazole | Papaverine | perfluorooctane sulfonic acid | perfluorooctanoic acid | Phenobarbital | piperine | Plant Extracts | Plant Preparations | Probucol | Propranolol | Propylthiouracil | Pyrazinamide | Quercetin | Quinidine | Resveratrol | Rifampin | Ritonavir | Rosiglitazone | Rutin | Saponins | Silymarin | Simvastatin | sodium arsenite | Streptozocin | Sulfasalazine | tetrabromobisphenol A | Thiamethoxam | Thioacetamide | thymoquinone | Tolbutamide | Topiramate | tris(chloroethyl)phosphate | troxerutin | ursolic acid | Zinc   584
5. positive regulation of cell death Hepatomegaly Inferred via 99 chemicals: 1-Deoxynojirimycin | 1-Naphthylisothiocyanate | 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | Acetaminophen | Acetylcysteine | Aflatoxin B1 | Amiodarone | Amitriptyline | Arsenic | Aspirin | Azathioprine | benz(a)anthracene | beta-Naphthoflavone | Bilirubin | bisphenol A | Cadmium Chloride | Caffeine | Carbamazepine | Cholesterol | Clozapine | Curcumin | Cyclophosphamide | delphinidin | Dexamethasone | Dichloroacetic Acid | Dichlorodiphenyl Dichloroethylene | Diclofenac | Diethylhexyl Phthalate | Disulfiram | Doxorubicin | Endosulfan | enilconazole | Environmental Pollutants | Ethanol | Ethinyl Estradiol | Fenofibrate | Flame Retardants | Fluoxetine | Flutamide | Fluvastatin | fumonisin B1 | geldanamycin | Genistein | Glutathione | Halogenated Diphenyl Ethers | Hydrocarbons, Chlorinated | Isoniazid | Ketoconazole | lead chloride | lead nitrate | lipopolysaccharide, E coli O55-B5 | Lipopolysaccharides | Lovastatin | Luteolin | Malondialdehyde | Methotrexate | Mycophenolic Acid | naphthalene | Nevirapine | nimesulide | obeticholic acid | Oxaliplatin | Papaverine | Pentachlorophenol | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | Phenobarbital | Phenytoin | piperine | Piperonyl Butoxide | Plant Extracts | Plant Preparations | Prednisolone | Propranolol | Propylthiouracil | Quercetin | Resveratrol | Riboflavin | Rifampin | Rosiglitazone | Rutin | Silymarin | Simvastatin | sodium arsenite | Streptozocin | Tamoxifen | tetrabromobisphenol A | Tetrachlorodibenzodioxin | Thioacetamide | Ticlopidine | Tretinoin | Triamcinolone Acetonide | tris(chloroethyl)phosphate | Valproic Acid | Verapamil | Vincristine | Zinc   489
6. response to oxidative stress Hepatomegaly Inferred via 95 chemicals: 1,2-Dimethylhydrazine | 3,4,5,3',4'-pentachlorobiphenyl | Acetaminophen | Acetylcysteine | alpha-naphthoflavone | Amikacin | Amiodarone | Amitriptyline | Arsenic | Aspirin | Azathioprine | beta-Naphthoflavone | Bilirubin | bisphenol A | Butylated Hydroxyanisole | Butylated Hydroxytoluene | Cadmium Chloride | Caffeine | Carbon Tetrachloride | Chloramphenicol | Chlorodiphenyl (54% Chlorine) | Clozapine | Curcumin | Cyclophosphamide | DDT | decabromobiphenyl ether | Dexamethasone | Diazepam | Dichlorodiphenyl Dichloroethylene | Diclofenac | Dietary Carbohydrates | Dietary Fats | Dietary Sucrose | Diethylnitrosamine | Diltiazem | Diosmin | Disulfiram | Doxorubicin | Enalapril | Ethanol | Fish Oils | Fluoxetine | Fluvastatin | Fructose | Genistein | Glutathione | Imipramine | Iron | Isoniazid | lead chloride | Lipopolysaccharides | Lovastatin | Malathion | Methimazole | Methionine | Mifepristone | Minocycline | Nelfinavir | nimesulide | nitrofen | Oxaliplatin | Phenobarbital | Plant Extracts | Plant Preparations | Probucol | Propofol | Propranolol | Propylthiouracil | Quercetin | Quinidine | Resveratrol | Riboflavin | Rifampin | Ritonavir | Rosiglitazone | Rutin | S-Adenosylmethionine | Saponins | Sevoflurane | Sildenafil Citrate | Silymarin | Simvastatin | sodium arsenite | Streptozocin | Sulfasalazine | Sulindac | Tamoxifen | Tetrachlorodibenzodioxin | Thioacetamide | Tocopherols | Topiramate | Tretinoin | Valproic Acid | Vitamin A | Zinc Inferred via 2 genes: CYGB | KEAP1 505
7. glutathione biosynthetic process Hepatomegaly Inferred via 89 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | Acetaminophen | Acetylcysteine | Aflatoxin B1 | alpha-naphthoflavone | Arsenic | Benzbromarone | Bilirubin | bisphenol A | Butylated Hydroxyanisole | Butylated Hydroxytoluene | Cadmium Chloride | Caffeine | Carbon Tetrachloride | Chlorodiphenyl (54% Chlorine) | chrysin | Ciprofloxacin | Clozapine | Curcumin | Cyclophosphamide | DDT | decabromobiphenyl ether | Dexamethasone | Dichloroacetic Acid | Diclofenac | Dietary Carbohydrates | Dietary Fats | Diethylhexyl Phthalate | Diethylnitrosamine | Doxorubicin | esculetin | Ethambutol | Ethanol | Fish Oils | Flutamide | Fructose | fumonisin B1 | Galactosamine | geldanamycin | Genistein | Glutathione | Hexachlorobenzene | indole-3-carbinol | Iron | Isoniazid | Ketoconazole | lipopolysaccharide, E coli O55-B5 | Lipopolysaccharides | Luteolin | Malathion | Metformin | Methimazole | Methionine | Methotrexate | Mifepristone | myricitrin | naphthalene | Omeprazole | perfluorooctane sulfonic acid | Phenobarbital | Phenytoin | piperine | Plant Extracts | Plant Preparations | Propylthiouracil | Pyrazinamide | Quercetin | Quinidine | Resveratrol | retrorsine | Rifampin | Rosiglitazone | Rutin | salvianolic acid B | Saponins | Silymarin | sodium arsenite | Streptozocin | Sulfasalazine | tetrabromobisphenol A | Tetrachlorodibenzodioxin | Thiamethoxam | Thioacetamide | thymoquinone | Topiramate | tris(chloroethyl)phosphate | troxerutin | ursolic acid | Zinc   496
8. membrane lipid catabolic process Hepatomegaly Inferred via 84 chemicals: 3,4,5,3',4'-pentachlorobiphenyl | Acetaminophen | Acetylcysteine | Amiodarone | Amitriptyline | Arsenic | Aspirin | beta-Naphthoflavone | Bilirubin | bisphenol A | Butylated Hydroxyanisole | Butylated Hydroxytoluene | Cadmium Chloride | Carbenicillin | Carbon Tetrachloride | Chlorodiphenyl (54% Chlorine) | Cholesterol | Choline | Clofibrate | Curcumin | Cyclophosphamide | decabromobiphenyl ether | Dexamethasone | Diclofenac | Dietary Carbohydrates | Diethylhexyl Phthalate | Diethylnitrosamine | Diethylstilbestrol | Diosmin | Disulfiram | Doxorubicin | Enalapril | Ethanol | Fish Oils | Fructose | Gemfibrozil | Glutathione | Iron | Iron-Dextran Complex | Isoniazid | Ketoconazole | Lipopolysaccharides | Lovastatin | Malathion | Malondialdehyde | Methapyrilene | Methionine | Methoxsalen | Mexiletine | nimesulide | Omeprazole | Phenobarbital | Piperonyl Butoxide | Plant Extracts | Plant Preparations | Probucol | Promethazine | Propofol | Propranolol | Propylthiouracil | Quercetin | Quinidine | Resveratrol | Rifampin | Rosiglitazone | Rutin | S-Adenosylmethionine | Sevoflurane | Sildenafil Citrate | Silymarin | Simvastatin | sodium arsenite | Streptozocin | Tamoxifen | tetrabromobisphenol A | Tetrachlorodibenzodioxin | Tetracycline | Ticlopidine | Tocopherols | Topiramate | Tretinoin | Vitamin A | Zinc | Zolpidem Inferred via 1 gene: CYP1B1 450
9. positive regulation of apoptotic process Hepatomegaly Inferred via 83 chemicals: 1,3-dichloro-2-propanol | Acetaminophen | Acetylcysteine | alpha-naphthoflavone | Amikacin | Amiodarone | Arsenic | Aspirin | Bilirubin | bisphenol A | Cadmium Chloride | Carbamazepine | Carbon Tetrachloride | Chlorodiphenyl (54% Chlorine) | Choline | Curcumin | Cyclophosphamide | Dactinomycin | Dexamethasone | Dichloroacetic Acid | Dichlorodiphenyl Dichloroethylene | Diclofenac | Dietary Fats | Diethylhexyl Phthalate | Diethylnitrosamine | Disulfiram | Doxorubicin | Endosulfan | Ethanol | ethylene dichloride | Flutamide | Fluvastatin | Fructose | fumonisin B1 | Galactosamine | Genistein | Glutathione | GW0742 | Isoniazid | Ketoconazole | lead chloride | lead nitrate | Lipopolysaccharides | Lovastatin | Metformin | Methionine | Methotrexate | Methoxsalen | methyleugenol | Minocycline | nitrofen | obeticholic acid | Oxaliplatin | perfluorooctane sulfonic acid | perfluorooctanoic acid | piperine | Plant Extracts | Plant Preparations | Propofol | Quercetin | Resveratrol | Rifampin | Rosiglitazone | salvianolic acid B | Silymarin | Simvastatin | sodium arsenite | Streptozocin | Sulindac | Tamoxifen | tebuconazole | tetrabromobisphenol A | Tetrachlorodibenzodioxin | Thioacetamide | tocotrienol, delta | Tretinoin | tris(1,3-dichloro-2-propyl)phosphate | tris(chloroethyl)phosphate | ursolic acid | Valproic Acid | Verapamil | Vincristine | Zinc Inferred via 6 genes: CYP1B1 | KLF11 | NOS2 | NOS3 | RELA | TGFB1 511
10. superoxide dismutase activity Hepatomegaly Inferred via 83 chemicals: 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | 2,4,5,2',4',5'-hexachlorobiphenyl | Acetaminophen | Acetylcysteine | Aflatoxin B1 | alpha-naphthoflavone | Amiodarone | Arsenic | Bilirubin | bisphenol A | Butylated Hydroxytoluene | Cadmium Chloride | Carbon Tetrachloride | Chitosan | Chlorodiphenyl (54% Chlorine) | Cholesterol, Dietary | Choline | chrysin | Curcumin | Cyclophosphamide | DDT | decabromobiphenyl ether | Dexamethasone | Diazepam | Dichloroacetic Acid | Diclofenac | Dietary Carbohydrates | Dietary Fats | Diethylhexyl Phthalate | Diethylnitrosamine | Doxorubicin | Endosulfan | esculetin | Ethambutol | Ethanol | fipronil | Fish Oils | Flutamide | Fructose | fumonisin B1 | Galactosamine | gastrodin | Genistein | Glutathione | indole-3-carbinol | Isoniazid | Lipopolysaccharides | Malathion | Mequindox | Metformin | Methionine | Methotrexate | oleuropein | Omeprazole | perfluorooctane sulfonic acid | perfluorooctanoic acid | Phenobarbital | piperine | Plant Extracts | Plant Preparations | Probucol | Propofol | Pyrazinamide | Quercetin | Resveratrol | Rifampin | Rosiglitazone | Rutin | Saponins | Silymarin | Simvastatin | sodium arsenite | Sodium Cholate | Streptozocin | tetrabromobisphenol A | Thioacetamide | thymoquinone | Topiramate | tris(chloroethyl)phosphate | troxerutin | ursolic acid | Zinc   453
11. reactive oxygen species biosynthetic process Hepatomegaly Inferred via 80 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | 3,4,5,3',4'-pentachlorobiphenyl | Acetaminophen | Acetylcysteine | Aflatoxin B1 | alpha-naphthoflavone | Amiodarone | Arsenic | Azathioprine | Bilirubin | bisphenol A | Butylated Hydroxyanisole | Cadmium Chloride | Carbon Tetrachloride | Cholesterol | Choline | chrysin | Ciprofloxacin | Curcumin | decabromobiphenyl ether | Dexamethasone | Dichloroacetic Acid | Dichlorodiphenyl Dichloroethylene | Diclofenac | Dietary Fats | Diethylhexyl Phthalate | Disulfiram | Doxorubicin | Endosulfan | esculetin | Ethanol | Ethinyl Estradiol | Fenofibrate | Flame Retardants | Fluoxetine | Flutamide | Fructose | fumonisin B1 | Galactosamine | gastrodin | Genistein | Glutathione | Halogenated Diphenyl Ethers | indole-3-carbinol | Iron | lead nitrate | lipopolysaccharide, E coli O55-B5 | Lipopolysaccharides | Luteolin | Methionine | nimesulide | octamethylcyclotetrasiloxane | perfluorooctane sulfonic acid | Plant Extracts | Plant Preparations | Propofol | Quercetin | Resveratrol | Ritonavir | Rutin | Saponins | Sildenafil Citrate | Silymarin | sodium arsenite | Streptozocin | Sulfasalazine | Tamoxifen | tetrabromobisphenol A | Tetrachlorodibenzodioxin | Tetracycline | Thioacetamide | Ticlopidine | Tretinoin | Trinitrotoluene | tris(1,3-dichloro-2-propyl)phosphate | tris(chloroethyl)phosphate | troxerutin | Valproic Acid | Verapamil | Zidovudine   416
12. positive regulation of cell proliferation Hepatomegaly Inferred via 79 chemicals: 1,2-Dimethylhydrazine | 1,4-bis(2-(3,5-dichloropyridyloxy))benzene | 1-Naphthylisothiocyanate | 2-Acetylaminofluorene | 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide | 4,4'-diaminodiphenylmethane | Acetylcysteine | Aflatoxin B1 | Arsenic | Aspirin | beta-Naphthoflavone | bisphenol A | Butylated Hydroxyanisole | Cadmium Chloride | Chlorodiphenyl (54% Chlorine) | Curcumin | delphinidin | Dexamethasone | Dichlorodiphenyl Dichloroethylene | Dietary Fats | Diethylhexyl Phthalate | Diethylnitrosamine | Diethylstilbestrol | Diosmin | Disulfiram | Doxorubicin | Endosulfan | Ethanol | Ethinyl Estradiol | ethylene dichloride | Fenbendazole | Fenofibrate | fipronil | Fluconazole | flumequine | Fluoxetine | Flutamide | fumonisin B1 | furan | Genistein | Glutathione | GW0742 | Iron | Ketoconazole | Lipopolysaccharides | Metformin | Methotrexate | Methoxsalen | Methoxychlor | methyleugenol | Mycophenolic Acid | N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide | Oxaliplatin | perfluorooctanoic acid | Phenobarbital | piperine | Plant Extracts | Plant Preparations | prochloraz | pronamide | Propofol | Quercetin | Resveratrol | Silymarin | sodium arsenite | Tamoxifen | tetrabromobisphenol A | Tetrachlorodibenzodioxin | Thioacetamide | thymoquinone | Tretinoin | Trichloroethylene | tris(1,3-dichloro-2-propyl)phosphate | tris(chloroethyl)phosphate | ursolic acid | Valproic Acid | Verteporfin | Vincristine | Zinc Inferred via 2 genes: RELA | TGFB1 395
13. positive regulation of reactive oxygen species biosynthetic process Hepatomegaly Inferred via 78 chemicals: 1,3-dichloro-2-propanol | 2,2',4,4'-tetrabromodiphenyl ether | 2,4-Dinitrophenol | 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide | 3,4,5,3',4'-pentachlorobiphenyl | Acetaminophen | Acetylcysteine | Aflatoxin B1 | alpha-naphthoflavone | Amikacin | Amitriptyline | Arsenic | benz(a)anthracene | Benzbromarone | bisphenol A | Cadmium Chloride | Carbon Tetrachloride | Cholesterol | Choline | Curcumin | Dactinomycin | delphinidin | Dexamethasone | Dichloroacetic Acid | Dichlorodiphenyl Dichloroethylene | Diclofenac | Dietary Fats | diethyl phthalate | Disulfiram | Doxorubicin | Enalapril | Endosulfan | enilconazole | Ethanol | ethylene dichloride | Fluoxetine | Flutamide | Genistein | Glutathione | Iron | Isoniazid | Ketoconazole | lead chloride | lead nitrate | lipopolysaccharide, E coli O55-B5 | Lipopolysaccharides | Malondialdehyde | Metformin | Methionine | Methotrexate | obeticholic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | piperine | pirinixic acid | Plant Extracts | Plant Preparations | Probucol | propiconazole | Propranolol | pyrene | Quercetin | quercetin 3-O-glucuronide | Resveratrol | Rifampin | Rosiglitazone | Silymarin | sodium arsenite | Streptozocin | tetrabromobisphenol A | Tetrachlorodibenzodioxin | Ticlopidine | Tretinoin | Trichloroethylene | tris(1,3-dichloro-2-propyl)phosphate | Valproic Acid | Verapamil | Zinc Inferred via 1 gene: CYBA 411
14. regulation of mitochondrial membrane potential Hepatomegaly Inferred via 78 chemicals: 1,2-Dimethylhydrazine | 1,3-dichloro-2-propanol | 2,2',4,4'-tetrabromodiphenyl ether | 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide | Acetaminophen | Acetylcysteine | Aflatoxin B1 | alpha-naphthoflavone | Amiodarone | Amitriptyline | Arsenic | Aspirin | Benzbromarone | bisphenol A | Cadmium Chloride | Caffeine | Carbon Tetrachloride | Ciprofloxacin | Clozapine | Curcumin | Dactinomycin | Dexamethasone | Diclofenac | Dietary Fats | Diethylhexyl Phthalate | Disulfiram | Doxorubicin | Endosulfan | esculetin | Ethanol | Fenofibrate | Flame Retardants | Flutamide | Fluvastatin | Fructose | fumonisin B1 | Glutathione | Halogenated Diphenyl Ethers | indole-3-carbinol | Iron | Isoflurane | lipopolysaccharide, E coli O55-B5 | Lipopolysaccharides | Mifepristone | Minocycline | nitrofen | Papaverine | perfluorooctane sulfonic acid | Phenobarbital | Phenytoin | Plant Extracts | Plant Preparations | Pyrazinamide | Quercetin | Resveratrol | Rosiglitazone | salvianolic acid B | Saponins | Sevoflurane | Sildenafil Citrate | Simvastatin | sodium arsenite | Streptozocin | Sulfasalazine | Sulindac | Tamoxifen | tetrabromobisphenol A | Tetrachlorodibenzodioxin | Tetracycline | thymoquinone | Ticlopidine | Tretinoin | Valproic Acid | Verapamil | Vincristine | Vitamin A | Zidovudine | Zinc   387
15. lipid oxidation Hepatomegaly Inferred via 76 chemicals: 1,3-dichloro-2-propanol | 1-Deoxynojirimycin | 2-Acetylaminofluorene | Acetaminophen | Acetylcysteine | Aflatoxin B1 | Arsenic | Aspirin | beta-Naphthoflavone | bisphenol A | Butylated Hydroxyanisole | Butylhydroxybutylnitrosamine | Cadmium Chloride | Carbamazepine | Carbon Tetrachloride | Cholesterol | Cholesterol, Dietary | Choline | chrysin | Curcumin | Cyclophosphamide | Dexamethasone | Diclofenac | Dietary Fats | Dietary Sucrose | Diethylnitrosamine | Doxorubicin | Enalapril | Endosulfan | enilconazole | Ethanol | Fenofibrate | Fluoxetine | Flutamide | Fructose | Genistein | Glutathione | Imipramine | Iron | Iron-Dextran Complex | lead chloride | lead nitrate | Lipopolysaccharides | Luteolin | Malondialdehyde | Metformin | Methionine | Methotrexate | Methoxsalen | obeticholic acid | oleuropein | Omeprazole | perfluorooctanoic acid | Piperonyl Butoxide | Plant Extracts | Probucol | propiconazole | Pyrazinamide | Quercetin | Resveratrol | Rosiglitazone | Rutin | S-Adenosylmethionine | Sevoflurane | Silymarin | Simvastatin | sodium arsenite | Sodium Cholate | Streptozocin | Sulfasalazine | Tamoxifen | Thioacetamide | thymoquinone | Vincristine | zileuton | Zinc   489
16. cholesterol biosynthetic process Hepatomegaly Inferred via 71 chemicals: 1-Naphthylisothiocyanate | (5'-(4-amino-7,7-dimethyl-2-trifluoromethyl-7H-pyrimido(4,5-b)(1,4)oxazin-6-yl)-2',3'-dihydrospiro(cyclohexane-1,1'-inden)-4-yl)acetic acid | Acetylcysteine | Aflatoxin B1 | Amiloride | Amiodarone | Bezafibrate | bisphenol A | Cadmium Chloride | Caffeine | Carbon Tetrachloride | Chitosan | Cholesterol | Cholesterol, Dietary | Choline | chrysin | Clofibrate | Curcumin | cyproconazole | Dexamethasone | Dietary Carbohydrates | Dietary Fats | Dietary Sucrose | Diethylnitrosamine | epoxiconazole | Ethanol | Fish Oils | Fluvastatin | Fructose | Galactosamine | ganoderic acid A | indole-3-carbinol | Isoniazid | lead nitrate | Lipopolysaccharides | Lovastatin | Luteolin | Metformin | Methimazole | Methionine | Mifepristone | oleuropein | Oligosaccharides | perfluorohexanesulfonic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | piperine | Plant Extracts | Plant Preparations | Probucol | prochloraz | Quercetin | quercetin 3-O-glucuronide | Resveratrol | Riboflavin | Ritonavir | Rosiglitazone | Rutin | salvianolic acid B | Scopoletin | Simvastatin | sodium arsenite | Streptozocin | Tetrachlorodibenzodioxin | Tetracycline | Thiamethoxam | Thioacetamide | thymoquinone | tocotrienol, delta | ursolic acid | Zidovudine   254
17. glutathione metabolic process Hepatomegaly Inferred via 70 chemicals: 1,3-dichloro-2-propanol | Acetaminophen | Acetylcysteine | Aflatoxin B1 | Arsenic | Aspirin | benz(a)anthracene | Benzbromarone | bisphenol A | Cadmium Chloride | Carbamazepine | Carbon Tetrachloride | Cholesterol | Cholesterol, Dietary | Curcumin | Cyclophosphamide | Dactinomycin | decabromobiphenyl ether | Dexamethasone | Diclofenac | Dietary Fats | Dietary Sucrose | Diethylnitrosamine | Disulfiram | Doxorubicin | Enalapril | Endosulfan | enilconazole | Environmental Pollutants | Ethanol | Fenofibrate | Fluoxetine | Flutamide | Fructose | Genistein | Glutathione | Iron-Dextran Complex | Ketoconazole | lead chloride | lead nitrate | Lipopolysaccharides | Methotrexate | obeticholic acid | Oligopeptides | Omeprazole | perfluorooctane sulfonic acid | Plant Extracts | Propranolol | Propylthiouracil | Pyrazinamide | pyrene | Quercetin | Resveratrol | Rosiglitazone | S-Adenosylmethionine | Silymarin | Simvastatin | sodium arsenite | Sodium Cholate | Streptozocin | Sulfasalazine | Tamoxifen | Thioacetamide | thymoquinone | Ticlopidine | Tretinoin | Valproic Acid | Verapamil | Vincristine | Zinc   448
18. DNA damage response, detection of DNA damage Hepatomegaly Inferred via 67 chemicals: 1,3-dichloro-2-propanol | 1-Naphthylisothiocyanate | 2,2',4,4'-tetrabromodiphenyl ether | 2-Acetylaminofluorene | 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide | 3,4,5,3',4'-pentachlorobiphenyl | Acetaminophen | Acetylcysteine | Aflatoxin B1 | alpha-naphthoflavone | Arsenic | Azathioprine | bisphenol A | Butylated Hydroxyanisole | Cadmium Chloride | Carbon Tetrachloride | clorophene | Curcumin | Cyclophosphamide | Dexamethasone | Diclofenac | Dicofol | Dietary Fats | Dietary Sucrose | Diethylhexyl Phthalate | Diethylnitrosamine | Diethylstilbestrol | Diosmin | Doxorubicin | enilconazole | Environmental Pollutants | Ethambutol | Ethanol | fipronil | Fish Oils | Flame Retardants | fumonisin B1 | geldanamycin | Glutathione | Halogenated Diphenyl Ethers | indole-3-carbinol | Isoniazid | Metformin | Methionine | methyleugenol | Methylnitrosourea | metolachlor | octamethylcyclotetrasiloxane | oleuropein | Pentachlorophenol | perfluorooctane sulfonic acid | Phenobarbital | Phenytoin | Plant Extracts | Pregnenolone Carbonitrile | Pyrazinamide | Quercetin | Resveratrol | Rifampin | Silymarin | Simvastatin | sodium arsenite | Streptozocin | Thioacetamide | Valproic Acid | Zidovudine | Zinc   306
19. triglyceride biosynthetic process Hepatomegaly Inferred via 67 chemicals: 1,4-bis(2-(3,5-dichloropyridyloxy))benzene | 2,4,5,2',4',5'-hexachlorobiphenyl | (5'-(4-amino-7,7-dimethyl-2-trifluoromethyl-7H-pyrimido(4,5-b)(1,4)oxazin-6-yl)-2',3'-dihydrospiro(cyclohexane-1,1'-inden)-4-yl)acetic acid | Acetylcysteine | Aflatoxin B1 | Amiloride | Amiodarone | Bezafibrate | bisphenol A | Cadmium Chloride | Carbon Tetrachloride | Chitosan | Cholesterol | Cholesterol, Dietary | Choline | Curcumin | cyproconazole | Dexamethasone | Dietary Carbohydrates | Dietary Fats | Dietary Sucrose | Diethylhexyl Phthalate | Diethylnitrosamine | Diethylstilbestrol | Doxorubicin | esculetin | Ethanol | ethylene dichloride | Fenofibrate | fipronil | Fish Oils | Fluvastatin | Fructose | ganoderic acid A | gardenin A | gastrodin | High Fructose Corn Syrup | indole-3-carbinol | Isoniazid | Lovastatin | Metformin | Methimazole | Methionine | perfluorooctanoic acid | piperine | Plant Extracts | Plant Preparations | Pyrazinamide | Quercetin | quercetin 3-O-glucuronide | Resveratrol | Riboflavin | Ritonavir | Rosiglitazone | Rutin | salvianolic acid B | Scopoletin | sodium arsenite | Streptozocin | tetrabromobisphenol A | Tetrachlorodibenzodioxin | Thioacetamide | tocotrienol, delta | UAB 30 | ursolic acid | Valproic Acid | Zidovudine   288
20. glutathione peroxidase activity Hepatomegaly Inferred via 67 chemicals: 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | 2,4,5,2',4',5'-hexachlorobiphenyl | 3,4,5,3',4'-pentachlorobiphenyl | Acetaminophen | Acetylcysteine | Aflatoxin B1 | Arsenic | bisphenol A | Cadmium Chloride | Caffeine | Carbon Tetrachloride | Chitosan | Cholesterol, Dietary | Choline | chrysin | Clozapine | Curcumin | Cyclophosphamide | decabromobiphenyl ether | Dexamethasone | Diazepam | Dichloroacetic Acid | Dichlorodiphenyl Dichloroethylene | Diclofenac | Dietary Carbohydrates | Dietary Fats | Diethylnitrosamine | Doxorubicin | Ethanol | Fish Oils | Fructose | Genistein | Hexachlorobenzene | indole-3-carbinol | Lipopolysaccharides | Luteolin | Malathion | Malondialdehyde | Mequindox | Metformin | Methotrexate | Mifepristone | Phenobarbital | piperine | Plant Extracts | Plant Preparations | Propofol | Propylthiouracil | Quercetin | Resveratrol | Rosiglitazone | Rutin | salvianolic acid B | Saponins | Silymarin | Simvastatin | sodium arsenite | Streptozocin | tetrabromobisphenol A | Tetrachlorodibenzodioxin | Thioacetamide | thymoquinone | tris(chloroethyl)phosphate | troxerutin | ursolic acid | Zinc   329
21. apoptotic DNA fragmentation Hepatomegaly Inferred via 66 chemicals: 1,2-Dimethylhydrazine | Acetaminophen | Acetylcysteine | Aflatoxin B1 | Amiloride | Amiodarone | Amitriptyline | Aspirin | Cadmium Chloride | Caffeine | Carbon Tetrachloride | Chitosan | chrysin | Clofibrate | Curcumin | Cyclophosphamide | Dactinomycin | Dexamethasone | Diclofenac | Disulfiram | Doxorubicin | Enalapril | esculetin | Ethanol | Fluoxetine | fumonisin B1 | Galactosamine | geldanamycin | Genistein | Imipramine | Isoniazid | lead nitrate | Lipopolysaccharides | Lovastatin | Luteolin | Malathion | Methionine | Mifepristone | Minocycline | nimesulide | Omeprazole | Oxaliplatin | Phenobarbital | Plant Extracts | Prednisolone | Propranolol | Pyrrolizidine Alkaloids | Quercetin | Resveratrol | Riboflavin | Rosiglitazone | S-Adenosylmethionine | Simvastatin | sodium arsenite | Stavudine | Streptozocin | Sulfasalazine | Sulindac | Tetrachlorodibenzodioxin | Tolbutamide | Tretinoin | Valproic Acid | Verapamil | Vincristine | Vitamin A | Zinc   333
22. detection of oxidative stress Hepatomegaly Inferred via 63 chemicals: 2,4,5,2',4',5'-hexachlorobiphenyl | 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide | 3,4,5,3',4'-pentachlorobiphenyl | Acetaminophen | Acetylcysteine | alpha-naphthoflavone | Amiodarone | Amitriptyline | Arsenic | bisphenol A | Cadmium Chloride | Carbamazepine | Carbon Tetrachloride | Chloramphenicol | Clozapine | coumarin | Curcumin | Dantrolene | Dietary Fats | Diethylhexyl Phthalate | Diethylnitrosamine | Disulfiram | Doxorubicin | Enalapril | Ethanol | Ethinyl Estradiol | Felbamate | Flutamide | Fructose | Isoniazid | Ketoconazole | Lipopolysaccharides | Metformin | Methapyrilene | Methiocarb | Methyldopa | nimesulide | PCB 180 | Phenacetin | Phenobarbital | Phenytoin | Piperonyl Butoxide | Plant Extracts | Plant Preparations | Quercetin | Resveratrol | Rifampin | Ritonavir | Rosiglitazone | Rutin | Saponins | Sildenafil Citrate | Simvastatin | sodium arsenite | Stavudine | Streptozocin | Sulindac | Tamoxifen | Thioacetamide | Valproic Acid | Verapamil | Zidovudine | Zinc   226
23. reactive oxygen species metabolic process Hepatomegaly Inferred via 60 chemicals: 1,3-dichloro-2-propanol | 2,2',4,4'-tetrabromodiphenyl ether | Acetaminophen | Acetylcysteine | Aflatoxin B1 | Arsenic | Azathioprine | Benzbromarone | beta-Naphthoflavone | Bilirubin | bisphenol A | Butylated Hydroxyanisole | Cadmium Chloride | Carbon Tetrachloride | Chlorodiphenyl (54% Chlorine) | Curcumin | DDT | Dexamethasone | Diethylnitrosamine | diethyl phthalate | Diethylstilbestrol | Diosmin | Doxorubicin | Endosulfan | Ethanol | Flutamide | Fructose | geldanamycin | Genistein | Glutathione | GW0742 | Hexachlorobenzene | Hydrocarbons, Chlorinated | Isoflurane | lead nitrate | lipopolysaccharide, E coli O55-B5 | Lipopolysaccharides | Luteolin | Metformin | myricitrin | Oligopeptides | Orphenadrine | Phenobarbital | Phenytoin | Piperonyl Butoxide | Plant Extracts | Plant Preparations | Propofol | Quercetin | Resveratrol | Rosiglitazone | Saponins | Silymarin | sodium arsenite | Streptozocin | thymoquinone | troxerutin | ursolic acid | Verapamil | Vitamin A Inferred via 2 genes: CYBA | SESN2 297
24. cell cycle Hepatomegaly Inferred via 60 chemicals: 3,4,5,3',4'-pentachlorobiphenyl | Acetaminophen | Acetylcysteine | alpha-naphthoflavone | Amiloride | Aspirin | bisphenol A | Caffeine | Cholesterol | chrysin | Ciprofloxacin | Clofibrate | Curcumin | Cyclophosphamide | Dactinomycin | Dexamethasone | Diethylstilbestrol | Doxorubicin | Fish Oils | flumequine | Fluvastatin | fumonisin B1 | Galactosamine | Genistein | Glutathione | GW0742 | indole-3-carbinol | Lovastatin | Methimazole | Methionine | Methotrexate | Methoxsalen | Mifepristone | Mycophenolic Acid | Nelfinavir | Nevirapine | nimesulide | nitrofen | Plant Extracts | Prednisolone | Propranolol | Quinidine | Resveratrol | Riboflavin | Rifampin | Ritonavir | Rosiglitazone | Simvastatin | sodium arsenite | Streptozocin | Sulindac | Tamoxifen | tetrabromobisphenol A | Tetrachlorodibenzodioxin | Thioacetamide | Tretinoin | Valproic Acid | Vincristine | Vitamin A | Zidovudine Inferred via 1 gene: AHR 306
25. regulation of blood pressure Hepatomegaly Inferred via 59 chemicals: Acetaminophen | Acetylcysteine | Amitriptyline | Arsenic | Aspirin | Bezafibrate | Caffeine | Chloramphenicol | Chlorpheniramine | Choline | Clofibrate | Desoxycorticosterone | Dexamethasone | Diazepam | Diclofenac | Dietary Sucrose | Diethylstilbestrol | Diltiazem | Disulfiram | Enalapril | Ethanol | Ethinyl Estradiol | Fenofibrate | Fluoxetine | Fructose | Glutathione | Imipramine | Iron | Isoflurane | Lipopolysaccharides | Metformin | Methimazole | Methionine | Methyldopa | Mexiletine | Mifepristone | Mycophenolic Acid | nimesulide | Papaverine | perfluorononanoic acid | perfluorooctane sulfonic acid | Phenobarbital | Plant Extracts | Propofol | Propranolol | Quercetin | Quinidine | Rosiglitazone | Sevoflurane | Sildenafil Citrate | Simvastatin | sodium arsenite | Streptozocin | Sulindac | Tetrachlorodibenzodioxin | Tolbutamide | Topiramate | Valproic Acid | Verapamil Inferred via 4 genes: AHR | CYBA | NOS2 | NOS3 593
26. mitotic cell cycle arrest Hepatomegaly Inferred via 53 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline | Acetylcysteine | ado-trastuzumab emtansine | Aflatoxin B1 | alpha-naphthoflavone | Arsenic | Azathioprine | beta-Naphthoflavone | bisphenol A | Butylated Hydroxyanisole | Cadmium Chloride | chrysin | Curcumin | Disulfiram | Doxorubicin | Endosulfan | esculetin | Ethambutol | Ethanol | Flame Retardants | fumonisin B1 | furan | geldanamycin | Glutathione | GW0742 | Halogenated Diphenyl Ethers | Hexachlorobenzene | Isoniazid | Metformin | Methionine | Methotrexate | Methylnitrosourea | Oxaliplatin | perfluorooctane sulfonic acid | perfluorooctanoic acid | Plant Extracts | Plant Preparations | Pregnenolone Carbonitrile | Propofol | Pyrazinamide | Quercetin | Resveratrol | Rifampin | Rosiglitazone | Rutin | sodium arsenite | Tetrachlorodibenzodioxin | Tretinoin | ursolic acid | Valproic Acid | Vincristine | Zinc   235
27. lipid biosynthetic process Hepatomegaly Inferred via 51 chemicals: 1,4-bis(2-(3,5-dichloropyridyloxy))benzene | 2,2',4,4'-tetrabromodiphenyl ether | 3,4,5,3',4'-pentachlorobiphenyl | Amiodarone | Aspirin | Azathioprine | Bezafibrate | bisphenol A | Caffeine | Chlorpropamide | Cholesterol | Clofibrate | Curcumin | cyproconazole | Dexamethasone | Dietary Fats | Doxorubicin | Ethanol | fenarimol | Fenofibrate | Fluoxetine | Fructose | gardenin A | Isoniazid | Mifepristone | myricitrin | obeticholic acid | pentabromodiphenyl ether | perfluorooctane sulfonic acid | perfluorooctanoic acid | Plant Extracts | prochloraz | Propranolol | Quercetin | quercetin 3-O-glucuronide | Resveratrol | Rifampin | Rosiglitazone | salvianolic acid B | Scopoletin | Silymarin | sodium arsenite | Streptozocin | Tamoxifen | Tetrachlorodibenzodioxin | Tetracycline | Ticlopidine | Topiramate | Valproic Acid | Zidovudine | Zinc   219
28. L-aspartate:2-oxoglutarate aminotransferase activity Hepatomegaly Inferred via 49 chemicals: 1-Naphthylisothiocyanate | (5'-(4-amino-7,7-dimethyl-2-trifluoromethyl-7H-pyrimido(4,5-b)(1,4)oxazin-6-yl)-2',3'-dihydrospiro(cyclohexane-1,1'-inden)-4-yl)acetic acid | Acetaminophen | Acetylcysteine | bisphenol A | Cadmium Chloride | Carbon Tetrachloride | Choline | chrysin | Curcumin | Cyclophosphamide | Dexamethasone | Diclofenac | Dietary Carbohydrates | Dietary Fats | Diethylhexyl Phthalate | Diethylnitrosamine | Doxorubicin | Ethanol | Ethinyl Estradiol | ethylene dichloride | Fructose | fumonisin B1 | Galactosamine | Genistein | Isoniazid | Lipopolysaccharides | Malathion | Metformin | Methapyrilene | Methionine | Methotrexate | octamethylcyclotetrasiloxane | Phenobarbital | piperine | pirinixic acid | Plant Extracts | Quercetin | Resveratrol | retrorsine | Rutin | salvianolic acid B | Silymarin | Streptozocin | Thiamethoxam | Thioacetamide | thymoquinone | ursolic acid | Zidovudine   207
29. nitric oxide biosynthetic process Hepatomegaly Inferred via 47 chemicals: 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide | Acetaminophen | Acetylcysteine | Aflatoxin B1 | alpha-naphthoflavone | Amiloride | Arsenic | bisphenol A | Cadmium Chloride | Caffeine | Carbon Tetrachloride | Choline | chrysin | Curcumin | Dexamethasone | Dietary Fats | Diethylnitrosamine | Doxorubicin | Endosulfan | Ethanol | fipronil | Flutamide | Fructose | Genistein | indole-3-carbinol | lipopolysaccharide, E coli O55-B5 | Lipopolysaccharides | Lovastatin | Methionine | Methotrexate | Mifepristone | Omeprazole | Phenobarbital | Plant Extracts | Plant Preparations | Quercetin | Resveratrol | Riboflavin | Rutin | salvianolic acid B | Silymarin | sodium arsenite | Streptozocin | Sulfasalazine | thymoquinone | tocotrienol, delta | ursolic acid Inferred via 3 genes: CYP1B1 | NOS2 | NOS3 260
30. positive regulation of superoxide dismutase activity Hepatomegaly Inferred via 47 chemicals: 2,2',4,4',5-brominated diphenyl ether | Acetaminophen | Acetylcysteine | Arsenic | bisphenol A | Butylated Hydroxyanisole | Butylhydroxybutylnitrosamine | Cadmium Chloride | Carbon Tetrachloride | Cholesterol | Curcumin | Cyclophosphamide | Dexamethasone | Dichlorodiphenyl Dichloroethylene | Diclofenac | Dietary Fats | Doxorubicin | Endosulfan | enilconazole | Ethanol | Fenofibrate | Fluoxetine | Fructose | Genistein | Glutathione | lead nitrate | lipopolysaccharide, E coli O55-B5 | Lipopolysaccharides | Methotrexate | oleuropein | Oligopeptides | Omeprazole | perfluorooctanoic acid | Plant Extracts | Probucol | propiconazole | Quercetin | Resveratrol | Saponins | Silymarin | sodium arsenite | Streptozocin | Sulfasalazine | thymoquinone | tris(chloroethyl)phosphate | Vincristine | Zinc   239
31. positive regulation of mitochondrial membrane potential Hepatomegaly Inferred via 47 chemicals: 1,3-dichloro-2-propanol | 2,2',4,4'-tetrabromodiphenyl ether | 2,4-Dinitrophenol | Acetaminophen | Acetylcysteine | Arsenic | Benzbromarone | bisphenol A | Butylhydroxybutylnitrosamine | Cadmium Chloride | Carbon Tetrachloride | Curcumin | Dactinomycin | Dichloroacetic Acid | Dichlorodiphenyl Dichloroethylene | Diclofenac | Diethylhexyl Phthalate | Disulfiram | Doxorubicin | Flutamide | Genistein | Glutathione | Isoniazid | lead nitrate | Lipopolysaccharides | Metformin | perfluorooctane sulfonic acid | Plant Extracts | Plant Preparations | Propranolol | Propylthiouracil | Quercetin | quercetin 3-O-glucuronide | Resveratrol | Rifampin | Rutin | Sevoflurane | sodium arsenite | Tamoxifen | tetrabromobisphenol A | Tetrachlorodibenzodioxin | Ticlopidine | Trichloroethylene | tris(1,3-dichloro-2-propyl)phosphate | Valproic Acid | Vincristine | Zinc   172
32. glutathione transferase activity Hepatomegaly Inferred via 46 chemicals: 1,2-Dimethylhydrazine | 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | Acetaminophen | Acetylcysteine | Aflatoxin B1 | Arsenic | beta-Naphthoflavone | bisphenol A | Butylated Hydroxyanisole | Cadmium Chloride | Carbon Tetrachloride | chlorpyrifos-methyl | coumarin | Curcumin | Cyclophosphamide | decabromobiphenyl ether | Dexamethasone | Dietary Fats | Diethylnitrosamine | Doxorubicin | Endosulfan | Ethanol | fipronil | Galactosamine | indole-3-carbinol | Isoniazid | Lipopolysaccharides | Malathion | metolachlor | Phenobarbital | Plant Extracts | Plant Preparations | Quercetin | Resveratrol | Silymarin | sodium arsenite | Streptozocin | tetrabromobisphenol A | Tetrachlorodibenzodioxin | Thiamethoxam | Thioacetamide | thymoquinone | tris(chloroethyl)phosphate | Vitamin A | Zinc   232
33. protein oxidation Hepatomegaly Inferred via 46 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | Acetaminophen | Acetylcysteine | Aflatoxin B1 | Arsenic | bisphenol A | Cadmium Chloride | Caffeine | Carbamazepine | Carbon Tetrachloride | Chlorodiphenyl (54% Chlorine) | Cholesterol | Cholesterol, Dietary | Curcumin | Dactinomycin | Dexamethasone | Diazepam | Dietary Fats | Diethylnitrosamine | Doxorubicin | Endosulfan | Ethanol | fumonisin B1 | Glutathione | Iron | lead nitrate | Lipopolysaccharides | Methionine | Methotrexate | Phenobarbital | Plant Extracts | Plant Preparations | Probucol | propiconazole | Quercetin | Resveratrol | Rutin | Silymarin | Simvastatin | sodium arsenite | Sodium Cholate | Streptozocin | Sulfasalazine | thymoquinone | zileuton | Zinc   230
34. leukocyte migration involved in inflammatory response Hepatomegaly Inferred via 45 chemicals: 3,4,5,3',4'-pentachlorobiphenyl | Acetaminophen | Acetylcysteine | bisphenol A | Caffeine | Carbon Tetrachloride | Choline | Curcumin | Dexamethasone | Diclofenac | Dietary Carbohydrates | Dietary Fats | Diethylnitrosamine | Doxorubicin | Ethanol | Fructose | Galactosamine | gastrodin | HFPO4 compound | indole-3-carbinol | lipopolysaccharide, E coli O55-B5 | Lipopolysaccharides | Metformin | Methapyrilene | Methionine | oleuropein | Omeprazole | oxadiazon | perfluorooctanoic acid | Plant Extracts | Quercetin | Resveratrol | Rutin | salvianolic acid B | Saponins | Streptozocin | Tamoxifen | Tetrachlorodibenzodioxin | Thiamethoxam | Thioacetamide | thymoquinone | Trichloroethylene | tris(1,3-dichloro-2-propyl)phosphate | ursolic acid | Zinc   207
35. negative regulation of cell proliferation Hepatomegaly Inferred via 43 chemicals: 1,3-dichloro-2-propanol | 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide | Acetaminophen | Acetylcysteine | alpha-naphthoflavone | benz(a)anthracene | bisphenol A | Cadmium Chloride | Chlorodiphenyl (54% Chlorine) | DDT | Dexamethasone | Dichlorodiphenyl Dichloroethylene | Diethylstilbestrol | Disulfiram | Doxorubicin | Ethanol | Ethinyl Estradiol | fipronil | Fluoxetine | Genistein | Glutathione | GW0742 | Isoflurane | Lipopolysaccharides | Metformin | Methoxychlor | Mifepristone | Piperonyl Butoxide | Plant Extracts | Prednisone | pyrene | Quercetin | Resveratrol | Rosiglitazone | Rutin | Simvastatin | sodium arsenite | Tamoxifen | Tetrachlorodibenzodioxin | ursolic acid | Valproic Acid | Vincristine | Zidovudine Inferred via 4 genes: CYP1B1 | KLF11 | NOS3 | TGFB1 189
36. vasodilation Hepatomegaly Inferred via 42 chemicals: Acetylcysteine | Amiodarone | Aspirin | Caffeine | Carbon Tetrachloride | Cholesterol | Desoxycorticosterone | Dexamethasone | Diclofenac | Dietary Carbohydrates | Dietary Fats | Diltiazem | Enalapril | Ethanol | Fructose | Glutathione | Iron | Isoflurane | Lipopolysaccharides | Metformin | Mexiletine | Mifepristone | Orotic Acid | Papaverine | Promethazine | Propofol | Propranolol | Quercetin | Quinidine | Resveratrol | Rosiglitazone | Sevoflurane | Sildenafil Citrate | Simvastatin | sodium arsenite | Streptozocin | Tamoxifen | Tetrachlorodibenzodioxin | Tolbutamide | Topiramate | Tretinoin | Verapamil Inferred via 3 genes: ALB | ATG5 | NOS3 249
37. alkaline phosphatase activity Hepatomegaly Inferred via 42 chemicals: 1-Naphthylisothiocyanate | Acetaminophen | Acetylcysteine | bisphenol A | Cadmium Chloride | Carbon Tetrachloride | chrysin | Curcumin | Cyclophosphamide | decabromobiphenyl ether | Dexamethasone | Diclofenac | Dietary Carbohydrates | Dietary Fats | Diethylhexyl Phthalate | Diethylnitrosamine | Doxorubicin | Endosulfan | Ethanol | Ethinyl Estradiol | Fructose | Halogenated Diphenyl Ethers | Isoniazid | Malathion | Metformin | Methapyrilene | Methotrexate | pentabromodiphenyl ether | Phenobarbital | Plant Extracts | Quercetin | Resveratrol | Silymarin | sodium arsenite | Streptozocin | Tetrachlorodibenzodioxin | Thiamethoxam | Thioacetamide | thymoquinone | troxerutin | Zidovudine | Zinc   202
38. vasoconstriction Hepatomegaly Inferred via 40 chemicals: Acetylcysteine | Amiodarone | Aspirin | Caffeine | chrysin | Curcumin | Dactinomycin | Dantrolene | Dexamethasone | Dietary Carbohydrates | Dietary Fats | Diltiazem | Enalapril | Ethanol | Fluoxetine | Fructose | Imipramine | Iron-Dextran Complex | Isoflurane | Lipopolysaccharides | Luteolin | Mexiletine | Mifepristone | Mycophenolic Acid | Papaverine | Plant Extracts | Prednisolone | Propofol | Propranolol | Quercetin | quercetin 3-O-glucuronide | Quinidine | Rosiglitazone | Saponins | Sevoflurane | Sildenafil Citrate | Streptozocin | Tetrachlorodibenzodioxin | Tolbutamide | Verapamil   234
39. cholesterol homeostasis Hepatomegaly Inferred via 39 chemicals: 1,3-dichloro-2-propanol | Acetylcysteine | bisphenol A | Carbon Tetrachloride | Cholesterol | Cholesterol, Dietary | Choline | Curcumin | Dietary Carbohydrates | Dietary Fats | Dietary Sucrose | diethyl phthalate | Doxorubicin | Enalapril | enilconazole | esculetin | Ethanol | Fenofibrate | Fluvastatin | Genistein | lead nitrate | Lipopolysaccharides | Metformin | Methionine | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | Plant Extracts | Plant Preparations | Pyrazinamide | Quercetin | Resveratrol | Silymarin | Simvastatin | sodium arsenite | Sodium Cholate | Streptozocin | tris(1,3-dichloro-2-propyl)phosphate | Zinc Inferred via 2 genes: NR1H2 | NR1H4 162
40. regulation of heart rate Hepatomegaly Inferred via 39 chemicals: 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide | Acetaminophen | Acetylcysteine | Amiodarone | Amitriptyline | Arsenic | Bezafibrate | Caffeine | Chloramphenicol | Clozapine | Dexamethasone | Diazepam | Diltiazem | Doxorubicin | Enalapril | Ethanol | Fluoxetine | Imipramine | Iron | Isoflurane | Lipopolysaccharides | Methimazole | Methionine | Methyldopa | Mexiletine | Papaverine | Phenobarbital | Plant Extracts | Propofol | Propranolol | Quinidine | Sevoflurane | Sildenafil Citrate | Simvastatin | Streptozocin | Tetrachlorodibenzodioxin | Tolbutamide | Topiramate | Verapamil   391
41. cell growth Hepatomegaly Inferred via 38 chemicals: 2,4,5,2',4',5'-hexachlorobiphenyl | 3,4,5,3',4'-pentachlorobiphenyl | Acetylcysteine | Aflatoxin B1 | Benzbromarone | bisphenol A | Butylated Hydroxyanisole | Butylated Hydroxytoluene | Cadmium Chloride | Carbamazepine | chrysin | Dexamethasone | Dichloroacetic Acid | Diclofenac | Doxorubicin | Ethanol | Ethinyl Estradiol | Fluoxetine | Flutamide | Glutathione | indole-3-carbinol | Ketoconazole | Luteolin | Methotrexate | PCB 180 | perfluorooctane sulfonic acid | perfluorooctanoic acid | Plant Extracts | Plant Preparations | Propranolol | Resveratrol | sodium arsenite | Thioacetamide | thymoquinone | Valproic Acid | Verapamil | Verteporfin | Vincristine Inferred via 1 gene: TGFB1 150
42. spermatogenesis Hepatomegaly Inferred via 38 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | 2,4,5,2',4',5'-hexachlorobiphenyl | Aflatoxin B1 | Arsenic | bisphenol A | chrysin | Cyclophosphamide | Danazol | decabromobiphenyl ether | Dichlorodiphenyl Dichloroethylene | Dietary Fats | Diethylhexyl Phthalate | diethyl phthalate | Diethylstilbestrol | Doxorubicin | Ethambutol | Ethanol | ethylene dichloride | fipronil | Fluoxetine | Flutamide | Genistein | Glutathione | Isoniazid | Methionine | perfluorooctane sulfonic acid | Plant Extracts | Pyrazinamide | Quercetin | Resveratrol | Rifampin | Sulfasalazine | Tamoxifen | Tetrachlorodibenzodioxin | Tretinoin | Trimethoprim, Sulfamethoxazole Drug Combination | Vitamin A | Zinc   149
43. cell migration Hepatomegaly Inferred via 37 chemicals: 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide | Acetylcysteine | alpha-naphthoflavone | Arsenic | bisphenol A | Cadmium Chloride | Carbamazepine | Carbon Tetrachloride | chrysin | Clozapine | Curcumin | Dexamethasone | Dichlorodiphenyl Dichloroethylene | Dietary Fats | Doxorubicin | Ethanol | Genistein | Hexachlorobenzene | indole-3-carbinol | Lipopolysaccharides | Luteolin | Metformin | Mifepristone | perfluorooctane sulfonic acid | perfluorooctanoic acid | Phenytoin | Plant Extracts | Pregnenolone Carbonitrile | Quercetin | Resveratrol | Rutin | sodium arsenite | Tetrachlorodibenzodioxin | thymoquinone | Valproic Acid | Verteporfin | zileuton Inferred via 1 gene: TGFB1 195
44. triglyceride homeostasis Hepatomegaly Inferred via 35 chemicals: 1,3-dichloro-2-propanol | 2,2',4,4'-tetrabromodiphenyl ether | bisphenol A | Carbon Tetrachloride | Cholates | Cholesterol, Dietary | Choline | cocoa butter | Curcumin | Dietary Carbohydrates | Dietary Fats | Dietary Sucrose | diethyl phthalate | Doxorubicin | esculetin | Ethanol | Fenofibrate | Fluvastatin | Genistein | Lipopolysaccharides | Metformin | Methionine | perfluorooctanoic acid | Plant Extracts | Plant Preparations | Pyrazinamide | Quercetin | Resveratrol | Silymarin | Simvastatin | sodium arsenite | Sodium Cholate | Streptozocin | thymoquinone | Zinc Inferred via 2 genes: NR1H4 | SESN2 120
45. cell differentiation Hepatomegaly Inferred via 35 chemicals: Acetylcysteine | Amiloride | Aspirin | bisphenol A | Chloramphenicol | chrysin | Clozapine | Curcumin | Cyclophosphamide | Dactinomycin | Dehydroepiandrosterone Sulfate | Dexamethasone | Diclofenac | Diethylstilbestrol | esculetin | Ethanol | Flutamide | Genistein | GW0742 | Lipopolysaccharides | Lovastatin | Metformin | Nevirapine | nimesulide | Omeprazole | Plant Extracts | Quercetin | Quinidine | Resveratrol | Rosiglitazone | Simvastatin | Tetrachlorodibenzodioxin | Tretinoin | Valproic Acid | Vitamin A   196
46. lactate dehydrogenase activity Hepatomegaly Inferred via 35 chemicals: Acetaminophen | Acetylcysteine | bisphenol A | Cadmium Chloride | Caffeine | Carbon Tetrachloride | Clofibrate | Clozapine | Curcumin | decabromobiphenyl ether | Dexamethasone | Dichlorodiphenyl Dichloroethylene | Dietary Carbohydrates | Dietary Fats | Diethylhexyl Phthalate | Diethylnitrosamine | Doxorubicin | Ethanol | lipopolysaccharide, E coli O55-B5 | Lipopolysaccharides | Malathion | Metformin | Methionine | Methotrexate | octamethylcyclotetrasiloxane | Plant Extracts | Quercetin | Resveratrol | Rutin | sodium arsenite | Streptozocin | Thiamethoxam | Thioacetamide | troxerutin | Zinc   180
47. positive regulation of p38MAPK cascade Hepatomegaly Inferred via 34 chemicals: 1,3-dichloro-2-propanol | 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide | Acetylcysteine | alpha-naphthoflavone | bisphenol A | Cadmium Chloride | Cholesterol | Curcumin | delphinidin | Dexamethasone | Dietary Fats | Disulfiram | Doxorubicin | Ethanol | Galactosamine | Genistein | Hexachlorobenzene | lipopolysaccharide, E coli O55-B5 | Lipopolysaccharides | Lovastatin | Luteolin | Methotrexate | Methoxychlor | perfluorooctane sulfonic acid | Plant Extracts | Propranolol | Quercetin | quercetin 3-O-glucuronide | Resveratrol | Rosiglitazone | sodium arsenite | Streptozocin | ursolic acid | Valproic Acid   174
48. ATP biosynthetic process Hepatomegaly Inferred via 33 chemicals: Acetaminophen | alpha-naphthoflavone | Benzbromarone | bisphenol A | Cadmium Chloride | Caffeine | Clozapine | Curcumin | cyproconazole | Dietary Fats | Diethylstilbestrol | Doxorubicin | Ethanol | Fenofibrate | Flutamide | Isoniazid | Ketoconazole | lipopolysaccharide, E coli O55-B5 | Lipopolysaccharides | Metformin | naphthalene | perfluorooctane sulfonic acid | piperine | Plant Extracts | Quercetin | Resveratrol | Rifampin | Rosiglitazone | Simvastatin | Streptozocin | Ticlopidine | Valproic Acid | Zinc Inferred via 1 gene: TGFB1 144
49. positive regulation of glutathione peroxidase activity Hepatomegaly Inferred via 33 chemicals: Acetaminophen | Acetylcysteine | Arsenic | bisphenol A | Cadmium Chloride | Carbon Tetrachloride | Cholesterol | chrysin | Curcumin | Cyclophosphamide | Dichlorodiphenyl Dichloroethylene | Dietary Fats | Diethylnitrosamine | Environmental Pollutants | Ethanol | Genistein | Glutathione | Iron | lead chloride | lead nitrate | Lipopolysaccharides | Methotrexate | Plant Extracts | Probucol | Quercetin | Resveratrol | Rosiglitazone | sodium arsenite | Streptozocin | Thioacetamide | thymoquinone | Vincristine | Zinc   167
50. testosterone biosynthetic process Hepatomegaly Inferred via 33 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | 2,4-Dinitrophenol | Acetylcysteine | bisphenol A | Cadmium Chloride | Curcumin | decabromobiphenyl ether | Dexamethasone | Dietary Fats | Diethylhexyl Phthalate | epoxiconazole | ethylene dichloride | Flutamide | Genistein | Halogenated Diphenyl Ethers | indole-3-carbinol | Ketoconazole | Methoxychlor | Mifepristone | Plant Extracts | propiconazole | Propylthiouracil | Quercetin | Resveratrol | Sildenafil Citrate | sodium arsenite | Streptozocin | Sulfasalazine | tebuconazole | tetrabromobisphenol A | Tetrachlorodibenzodioxin | tris(1,3-dichloro-2-propyl)phosphate | tris(chloroethyl)phosphate   142
1–50 of 3,655 results.