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Disease Huntington Disease

Name Huntington Disease
Synonyms Akinetic Rigid Variant of Huntington Disease | Akinetic-Rigid Variant of Huntington Disease | Chorea, Chronic Progressive Hereditary (Huntington) | Chorea, Huntington | Chorea, Huntington's | Chronic Progressive Hereditary Chorea (Huntington) | HD | Huntington Chorea | Huntington Chronic Progressive Hereditary Chorea | Huntington Disease, Akinetic Rigid Variant | Huntington Disease, Akinetic-Rigid Variant | Huntington Disease, Juvenile | Huntington Disease, Juvenile Onset | Huntington Disease, Juvenile-Onset | Huntington Disease, Late Onset | Huntington Disease, Late-Onset | Huntington's Chorea | Huntington's Disease | Juvenile Huntington Disease | Juvenile Onset Huntington Disease | Juvenile-Onset Huntington Disease | Late Onset Huntington Disease | Late-Onset Huntington Disease | Progressive Chorea, Chronic Hereditary (Huntington) | Progressive Chorea, Hereditary, Chronic (Huntington)
Definition A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)
Categories Genetic disease (inborn) | Mental disorder | Nervous system disease
MeSH® ID D006816
OMIM® ID 143100
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1. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Central Nervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Brain Diseases Has associated chemicals Has associated genes Has associated exposure references Basal Ganglia Diseases Has associated chemicals Has associated genes Has associated exposure references Huntington Disease Has associated chemicals Has associated genes
2. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Central Nervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Brain Diseases Has associated chemicals Has associated genes Has associated exposure references Dementia Has associated chemicals Has associated genes Has associated exposure references Huntington Disease Has associated chemicals Has associated genes
3. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Central Nervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Movement Disorders Has associated chemicals Has associated genes Has associated exposure references Dyskinesias Has associated chemicals Has associated genes Has associated exposure references Chorea Has associated chemicals Has associated genes Huntington Disease Has associated chemicals Has associated genes
4. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Neurodegenerative Diseases Has associated chemicals Has associated genes Has associated exposure references Heredodegenerative Disorders, Nervous System Has associated chemicals Has associated genes Huntington Disease Has associated chemicals Has associated genes
5. DiseasesCongenital, Hereditary, and Neonatal Diseases and Abnormalities Has associated chemicals Has associated genes Has associated exposure references Genetic Diseases, Inborn Has associated chemicals Has associated genes Has associated exposure references Heredodegenerative Disorders, Nervous System Has associated chemicals Has associated genes Huntington Disease Has associated chemicals Has associated genes
6. DiseasesMental Disorders Has associated chemicals Has associated genes Has associated exposure references Neurocognitive Disorders Has associated chemicals Has associated genes Has associated exposure references Cognition Disorders Has associated chemicals Has associated genes Has associated exposure references Huntington Disease Has associated chemicals Has associated genes
7. DiseasesMental Disorders Has associated chemicals Has associated genes Has associated exposure references Neurocognitive Disorders Has associated chemicals Has associated genes Has associated exposure references Dementia Has associated chemicals Has associated genes Has associated exposure references Huntington Disease Has associated chemicals Has associated genes

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Huntington Disease Has associated chemicals Has associated genes
  Huntington Disease-Like 1 Has associated chemicals Has associated genes
  Huntington Disease-Like 3
  Westphal disease Has associated chemicals Has associated genes