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Disease Hypoaldosteronism

Name Hypoaldosteronism
Synonyms Acidosis, Renal Tubular Type IV | Hypoaldosteronism, Hyporeninemic | Hyporeninemic Hypoaldosteronism | Renal Tubular Acidosis, Type IV | Type IV Renal Tubular Acidosis
Definition A congenital or acquired condition of insufficient production of ALDOSTERONE by the ADRENAL CORTEX leading to diminished aldosterone-mediated synthesis of Na(+)-K(+)-EXCHANGING ATPASE in renal tubular cells. Clinical symptoms include HYPERKALEMIA, sodium-wasting, HYPOTENSION, and sometimes metabolic ACIDOSIS.
Categories Endocrine system disease
MeSH® ID D006994

Top ↑ Ancestors

DiseasesEndocrine System Diseases Has associated chemicals Has associated genes Has associated exposure references Adrenal Gland Diseases Has associated chemicals Has associated genes Adrenal Insufficiency Has associated chemicals Has associated genes Hypoaldosteronism Has associated chemicals Has associated genes

Top ↑ Descendants

Hypoaldosteronism Has associated chemicals Has associated genes
  18-Hydroxylase deficiency Has associated chemicals Has associated genes
  Hyperreninemic Hypoaldosteronism, Familial, 2