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Disease Disorders of Environmental Origin

These phenotypes are associated with Disorders of Environmental Origin or its descendants. A phenotype has an inferred association via a curated chemical interaction or a gene-GO annotation or both.

1–50 of 906 results.
  Phenotype Disease Chemical Inference Network Gene Inference Network References
1. DNA damage response, detection of DNA damage Disorders of Environmental Origin Inferred via 5 chemicals: Acrolein | Formaldehyde | metolachlor | Ozone | Particulate Matter   35
2. cell proliferation Disorders of Environmental Origin Inferred via 5 chemicals: Acrolein | Formaldehyde | metolachlor | Ozone | Particulate Matter   33
3. response to oxidative stress Multiple Chemical Sensitivity Inferred via 4 chemicals: Acetaminophen | Aspirin | Hexachlorocyclohexane | Tobacco Smoke Pollution Inferred via 1 gene: SOD2 22
4. apoptotic process Disorders of Environmental Origin Inferred via 4 chemicals: Acrolein | Formaldehyde | Ozone | Particulate Matter   22
5. response to oxidative stress Disorders of Environmental Origin Inferred via 4 chemicals: 1,6-hexamethylene diisocyanate | Acrolein | Ozone | Particulate Matter   9
6. positive regulation of cytokine production involved in inflammatory response Disorders of Environmental Origin Inferred via 4 chemicals: Acrolein | Formaldehyde | Ozone | Particulate Matter   5
7. positive regulation of cell death Disorders of Environmental Origin Inferred via 4 chemicals: Acrolein | Chlorine | Formaldehyde | Particulate Matter   19
8. cell migration Disorders of Environmental Origin Inferred via 4 chemicals: Acrolein | Chlorine | Formaldehyde | Particulate Matter   6
9. reactive oxygen species biosynthetic process Disorders of Environmental Origin Inferred via 4 chemicals: Acrolein | Formaldehyde | Ozone | Particulate Matter   25
10. cell death Disorders of Environmental Origin Inferred via 4 chemicals: Acrolein | Formaldehyde | Ozone | Particulate Matter   18
11. glutathione peroxidase activity Disorders of Environmental Origin Inferred via 4 chemicals: Acrolein | Formaldehyde | Ozone | Particulate Matter   5
12. inflammatory response Disorders of Environmental Origin Inferred via 4 chemicals: Acrolein | Formaldehyde | Ozone | Particulate Matter   16
13. apoptotic process Multiple Chemical Sensitivity Inferred via 4 chemicals: Acetaminophen | Aspirin | Hexachlorocyclohexane | Tobacco Smoke Pollution   61
14. positive regulation of cell death Multiple Chemical Sensitivity Inferred via 4 chemicals: Acetaminophen | Aspirin | Pentachlorophenol | Tobacco Smoke Pollution   22
15. glutathione biosynthetic process Disorders of Environmental Origin Inferred via 4 chemicals: Acrolein | Formaldehyde | Ozone | Particulate Matter   10
16. superoxide dismutase activity Disorders of Environmental Origin Inferred via 4 chemicals: Acrolein | Formaldehyde | Ozone | Particulate Matter   7
17. negative regulation of cell proliferation Disorders of Environmental Origin Inferred via 4 chemicals: Acrolein | Formaldehyde | metolachlor | Particulate Matter   8
18. lipid catabolic process Multiple Chemical Sensitivity Inferred via 4 chemicals: Acetaminophen | Aspirin | Hexachlorocyclohexane | Tobacco Smoke Pollution   17
19. cell death Multiple Chemical Sensitivity Inferred via 4 chemicals: Acetaminophen | Aspirin | Hexachlorocyclohexane | Tobacco Smoke Pollution   23
20. membrane lipid catabolic process Multiple Chemical Sensitivity Inferred via 4 chemicals: Acetaminophen | Aspirin | Hexachlorocyclohexane | Tobacco Smoke Pollution   25
21. regulation of mitochondrial membrane potential Multiple Chemical Sensitivity Inferred via 3 chemicals: Acetaminophen | Aspirin | Tobacco Smoke Pollution Inferred via 1 gene: SOD2 13
22. regulation of blood pressure Multiple Chemical Sensitivity Inferred via 3 chemicals: Acetaminophen | Aspirin | Tobacco Smoke Pollution Inferred via 1 gene: SOD2 12
23. glutathione metabolic process Multiple Chemical Sensitivity Inferred via 3 chemicals: Acetaminophen | Aspirin | Tobacco Smoke Pollution Inferred via 1 gene: SOD2 17
24. superoxide dismutase activity Multiple Chemical Sensitivity Inferred via 3 chemicals: Acetaminophen | Hexachlorocyclohexane | Tobacco Smoke Pollution Inferred via 1 gene: SOD2 16
25. nitric oxide biosynthetic process Disorders of Environmental Origin Inferred via 3 chemicals: Acrolein | Formaldehyde | Particulate Matter   4
26. cell proliferation Multiple Chemical Sensitivity Inferred via 3 chemicals: Acetaminophen | Aspirin | Tobacco Smoke Pollution   45
27. protein oxidation Disorders of Environmental Origin Inferred via 3 chemicals: Acrolein | Ozone | Particulate Matter   4
28. positive regulation of apoptotic process Multiple Chemical Sensitivity Inferred via 3 chemicals: Acetaminophen | Aspirin | Tobacco Smoke Pollution   11
29. positive regulation of reactive oxygen species biosynthetic process Disorders of Environmental Origin Inferred via 3 chemicals: Formaldehyde | Ozone | Particulate Matter   10
30. positive regulation of protein import into nucleus Multiple Chemical Sensitivity Inferred via 3 chemicals: Acetaminophen | Aspirin | Tobacco Smoke Pollution   4
31. positive regulation of JNK cascade Multiple Chemical Sensitivity Inferred via 3 chemicals: Acetaminophen | Hexachlorocyclohexane | Tobacco Smoke Pollution   7
32. DNA damage response, detection of DNA damage Multiple Chemical Sensitivity Inferred via 3 chemicals: Acetaminophen | Pentachlorophenol | Tobacco Smoke Pollution   8
33. leukocyte chemotaxis Multiple Chemical Sensitivity Inferred via 3 chemicals: Acetaminophen | Aspirin | Tobacco Smoke Pollution   4
34. regulation of heart rate Disorders of Environmental Origin Inferred via 3 chemicals: Acrolein | Ozone | Particulate Matter   7
35. cell cycle Multiple Chemical Sensitivity Inferred via 3 chemicals: Acetaminophen | Aspirin | Tobacco Smoke Pollution   15
36. lipid oxidation Multiple Chemical Sensitivity Inferred via 3 chemicals: Acetaminophen | Aspirin | Tobacco Smoke Pollution   10
37. positive regulation of collagen biosynthetic process Multiple Chemical Sensitivity Inferred via 3 chemicals: Acetaminophen | Aspirin | Tobacco Smoke Pollution   4
38. mitotic cell cycle arrest Disorders of Environmental Origin Inferred via 3 chemicals: Acrolein | Formaldehyde | Particulate Matter   5
39. positive regulation of apoptotic process Disorders of Environmental Origin Inferred via 3 chemicals: Acrolein | Formaldehyde | Particulate Matter   9
40. glutathione biosynthetic process Multiple Chemical Sensitivity Inferred via 3 chemicals: Acetaminophen | Hexachlorocyclohexane | Tobacco Smoke Pollution   31
41. lipid oxidation Disorders of Environmental Origin Inferred via 3 chemicals: Acrolein | Ozone | Particulate Matter   6
42. negative regulation of cell proliferation Multiple Chemical Sensitivity Inferred via 2 chemicals: Acetaminophen | Tobacco Smoke Pollution Inferred via 1 gene: SOD2 5
43. reactive oxygen species metabolic process Multiple Chemical Sensitivity Inferred via 2 chemicals: Acetaminophen | Tobacco Smoke Pollution Inferred via 1 gene: SOD2 10
44. mitochondrion organization Multiple Chemical Sensitivity Inferred via 2 chemicals: Acetaminophen | Tobacco Smoke Pollution Inferred via 1 gene: SOD2 4
45. vasodilation Multiple Chemical Sensitivity Inferred via 2 chemicals: Aspirin | Tobacco Smoke Pollution Inferred via 1 gene: SOD2 14
46. respiratory gaseous exchange Disorders of Environmental Origin Inferred via 2 chemicals: Ozone | Particulate Matter   3
47. learning or memory Disorders of Environmental Origin Inferred via 2 chemicals: Ozone | Particulate Matter   3
48. memory Disorders of Environmental Origin Inferred via 2 chemicals: Formaldehyde | Particulate Matter   3
49. positive regulation of p38MAPK cascade Disorders of Environmental Origin Inferred via 2 chemicals: 1,6-hexamethylene diisocyanate | Particulate Matter   4
50. detection of oxidative stress Disorders of Environmental Origin Inferred via 2 chemicals: Acrolein | Particulate Matter   4
1–50 of 906 results.