Skip navigation

Disease Disorders of Environmental Origin

These phenotypes are associated with Disorders of Environmental Origin or its descendants. A phenotype has an inferred association via a curated chemical interaction or a gene-GO annotation or both.

1–50 of 836 results.
  Phenotype Disease Chemical Inference Network Gene Inference Network References
1. DNA damage response, detection of DNA damage Disorders of Environmental Origin Inferred via 5 chemicals: Acrolein | Formaldehyde | metolachlor | Ozone | Particulate Matter   34
2. cell proliferation Disorders of Environmental Origin Inferred via 5 chemicals: Acrolein | Formaldehyde | metolachlor | Ozone | Particulate Matter   31
3. response to oxidative stress Multiple Chemical Sensitivity Inferred via 4 chemicals: Acetaminophen | Aspirin | Hexachlorocyclohexane | Tobacco Smoke Pollution Inferred via 1 gene: SOD2 22
4. cell death Disorders of Environmental Origin Inferred via 4 chemicals: Acrolein | Formaldehyde | Ozone | Particulate Matter   16
5. glutathione biosynthetic process Disorders of Environmental Origin Inferred via 4 chemicals: Acrolein | Formaldehyde | Ozone | Particulate Matter   9
6. superoxide dismutase activity Disorders of Environmental Origin Inferred via 4 chemicals: Acrolein | Formaldehyde | Ozone | Particulate Matter   5
7. membrane lipid catabolic process Multiple Chemical Sensitivity Inferred via 4 chemicals: Acetaminophen | Aspirin | Hexachlorocyclohexane | Tobacco Smoke Pollution   25
8. positive regulation of cell death Disorders of Environmental Origin Inferred via 4 chemicals: Acrolein | Chlorine | Formaldehyde | Particulate Matter   19
9. apoptotic process Multiple Chemical Sensitivity Inferred via 4 chemicals: Acetaminophen | Aspirin | Hexachlorocyclohexane | Tobacco Smoke Pollution   61
10. apoptotic process Disorders of Environmental Origin Inferred via 4 chemicals: Acrolein | Formaldehyde | Ozone | Particulate Matter   20
11. glutathione peroxidase activity Disorders of Environmental Origin Inferred via 4 chemicals: Acrolein | Formaldehyde | Ozone | Particulate Matter   4
12. response to oxidative stress Disorders of Environmental Origin Inferred via 4 chemicals: 1,6-hexamethylene diisocyanate | Acrolein | Ozone | Particulate Matter   9
13. cell death Multiple Chemical Sensitivity Inferred via 4 chemicals: Acetaminophen | Aspirin | Hexachlorocyclohexane | Tobacco Smoke Pollution   22
14. positive regulation of cell death Multiple Chemical Sensitivity Inferred via 4 chemicals: Acetaminophen | Aspirin | Pentachlorophenol | Tobacco Smoke Pollution   22
15. regulation of blood pressure Multiple Chemical Sensitivity Inferred via 3 chemicals: Acetaminophen | Aspirin | Tobacco Smoke Pollution Inferred via 1 gene: SOD2 12
16. regulation of mitochondrial membrane potential Multiple Chemical Sensitivity Inferred via 3 chemicals: Acetaminophen | Aspirin | Tobacco Smoke Pollution Inferred via 1 gene: SOD2 13
17. glutathione metabolic process Multiple Chemical Sensitivity Inferred via 3 chemicals: Acetaminophen | Aspirin | Tobacco Smoke Pollution Inferred via 1 gene: SOD2 15
18. positive regulation of cytokine production involved in inflammatory response Disorders of Environmental Origin Inferred via 3 chemicals: Formaldehyde | Ozone | Particulate Matter   4
19. positive regulation of JNK cascade Multiple Chemical Sensitivity Inferred via 3 chemicals: Acetaminophen | Hexachlorocyclohexane | Tobacco Smoke Pollution   7
20. inflammatory response Disorders of Environmental Origin Inferred via 3 chemicals: Acrolein | Ozone | Particulate Matter   14
21. positive regulation of apoptotic process Multiple Chemical Sensitivity Inferred via 3 chemicals: Acetaminophen | Aspirin | Tobacco Smoke Pollution   9
22. cell proliferation Multiple Chemical Sensitivity Inferred via 3 chemicals: Acetaminophen | Aspirin | Tobacco Smoke Pollution   44
23. lipid oxidation Multiple Chemical Sensitivity Inferred via 3 chemicals: Acetaminophen | Aspirin | Tobacco Smoke Pollution   9
24. positive regulation of reactive oxygen species biosynthetic process Disorders of Environmental Origin Inferred via 3 chemicals: Formaldehyde | Ozone | Particulate Matter   10
25. nitric oxide biosynthetic process Disorders of Environmental Origin Inferred via 3 chemicals: Acrolein | Formaldehyde | Particulate Matter   4
26. reactive oxygen species biosynthetic process Disorders of Environmental Origin Inferred via 3 chemicals: Formaldehyde | Ozone | Particulate Matter   21
27. leukocyte chemotaxis Multiple Chemical Sensitivity Inferred via 3 chemicals: Acetaminophen | Aspirin | Tobacco Smoke Pollution   4
28. lipid catabolic process Multiple Chemical Sensitivity Inferred via 3 chemicals: Acetaminophen | Aspirin | Tobacco Smoke Pollution   14
29. cell cycle Multiple Chemical Sensitivity Inferred via 3 chemicals: Acetaminophen | Aspirin | Tobacco Smoke Pollution   15
30. protein oxidation Disorders of Environmental Origin Inferred via 3 chemicals: Acrolein | Ozone | Particulate Matter   4
31. glutathione biosynthetic process Multiple Chemical Sensitivity Inferred via 3 chemicals: Acetaminophen | Hexachlorocyclohexane | Tobacco Smoke Pollution   28
32. lipid oxidation Disorders of Environmental Origin Inferred via 3 chemicals: Acrolein | Ozone | Particulate Matter   6
33. positive regulation of collagen biosynthetic process Multiple Chemical Sensitivity Inferred via 3 chemicals: Acetaminophen | Aspirin | Tobacco Smoke Pollution   4
34. regulation of heart rate Disorders of Environmental Origin Inferred via 3 chemicals: Acrolein | Ozone | Particulate Matter   6
35. negative regulation of cell proliferation Disorders of Environmental Origin Inferred via 3 chemicals: Acrolein | Formaldehyde | Particulate Matter   5
36. negative regulation of cell proliferation Multiple Chemical Sensitivity Inferred via 2 chemicals: Acetaminophen | Tobacco Smoke Pollution Inferred via 1 gene: SOD2 5
37. reactive oxygen species metabolic process Multiple Chemical Sensitivity Inferred via 2 chemicals: Acetaminophen | Tobacco Smoke Pollution Inferred via 1 gene: SOD2 10
38. vasodilation Multiple Chemical Sensitivity Inferred via 2 chemicals: Aspirin | Tobacco Smoke Pollution Inferred via 1 gene: SOD2 14
39. superoxide dismutase activity Multiple Chemical Sensitivity Inferred via 2 chemicals: Acetaminophen | Tobacco Smoke Pollution Inferred via 1 gene: SOD2 13
40. mitochondrion organization Multiple Chemical Sensitivity Inferred via 2 chemicals: Acetaminophen | Tobacco Smoke Pollution Inferred via 1 gene: SOD2 4
41. lymphocyte chemotaxis Disorders of Environmental Origin Inferred via 2 chemicals: Ozone | Particulate Matter   4
42. swimming behavior Disorders of Environmental Origin Inferred via 2 chemicals: Acrolein | Particulate Matter   2
43. hydrogen peroxide biosynthetic process Disorders of Environmental Origin Inferred via 2 chemicals: Acrolein | Particulate Matter   3
44. positive regulation of monocyte extravasation Disorders of Environmental Origin Inferred via 2 chemicals: Ozone | Particulate Matter   3
45. positive regulation of neutrophil extravasation Disorders of Environmental Origin Inferred via 2 chemicals: Ozone | Particulate Matter   4
46. positive regulation of autophagosome assembly Disorders of Environmental Origin Inferred via 2 chemicals: Formaldehyde | Particulate Matter   3
47. regulation of inflammatory response Disorders of Environmental Origin Inferred via 2 chemicals: Ozone | Particulate Matter   3
48. glutathione metabolic process Disorders of Environmental Origin Inferred via 2 chemicals: Acrolein | Particulate Matter   5
49. glutathione metabolic process Environmental Illness Inferred via 2 chemicals: chromium hexavalent ion | Vehicle Emissions   5
50. detection of oxidative stress Disorders of Environmental Origin Inferred via 2 chemicals: Acrolein | Particulate Matter   4
1–50 of 836 results.