Skip navigation

Disease Leukoencephalopathy, Progressive Multifocal

Name Leukoencephalopathy, Progressive Multifocal
Synonyms Encephalitis, JC Polyomavirus | Encephalopathies, JC Polyomavirus | Encephalopathy, JC Polyomavirus | JC Polyomavirus Encephalitis | JC Polyomavirus Encephalopathy | Leukoencephalopathies, Progressive Multifocal | Multifocal Leukoencephalopathies, Progressive | Multifocal Leukoencephalopathy, Progressive | Progressive Multifocal Leukoencephalopathies | Progressive Multifocal Leukoencephalopathy
Definition An opportunistic viral infection of the central nervous system associated with conditions that impair cell-mediated immunity (e.g., ACQUIRED IMMUNODEFICIENCY SYNDROME and other IMMUNOLOGIC DEFICIENCY SYNDROMES; HEMATOLOGIC NEOPLASMS; IMMUNOSUPPRESSION; and COLLAGEN DISEASES). The causative organism is JC Polyomavirus (JC VIRUS) which primarily affects oligodendrocytes, resulting in multiple areas of demyelination. Clinical manifestations include DEMENTIA; ATAXIA; visual disturbances; and other focal neurologic deficits, generally progressing to a vegetative state within 6 months. (From Joynt, Clinical Neurology, 1996, Ch26, pp36-7)
Categories Nervous system disease | Viral disease
MeSH® ID D007968
External Links

Top ↑ Ancestors

1. DiseasesVirus Diseases Has associated chemicals Has associated genes Has associated exposure references Central Nervous System Viral Diseases Has associated chemicals Has associated genes Encephalitis, Viral Has associated chemicals Has associated genes Leukoencephalopathy, Progressive Multifocal Has associated chemicals Has associated genes
2. DiseasesVirus Diseases Has associated chemicals Has associated genes Has associated exposure references DNA Virus Infections Has associated chemicals Has associated genes Has associated exposure references Polyomavirus Infections Has associated chemicals Has associated genes Leukoencephalopathy, Progressive Multifocal Has associated chemicals Has associated genes
3. DiseasesVirus Diseases Has associated chemicals Has associated genes Has associated exposure references Encephalitis, Viral Has associated chemicals Has associated genes Leukoencephalopathy, Progressive Multifocal Has associated chemicals Has associated genes
4. DiseasesVirus Diseases Has associated chemicals Has associated genes Has associated exposure references Slow Virus Diseases Has associated chemicals Has associated genes Leukoencephalopathy, Progressive Multifocal Has associated chemicals Has associated genes
5. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Central Nervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Brain Diseases Has associated chemicals Has associated genes Has associated exposure references Encephalitis Has associated chemicals Has associated genes Infectious Encephalitis Has associated chemicals Has associated genes Encephalitis, Viral Has associated chemicals Has associated genes Leukoencephalopathy, Progressive Multifocal Has associated chemicals Has associated genes
6. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Central Nervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Brain Diseases Has associated chemicals Has associated genes Has associated exposure references Leukoencephalopathies Has associated chemicals Has associated genes Has associated exposure references Leukoencephalopathy, Progressive Multifocal Has associated chemicals Has associated genes
7. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Central Nervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Central Nervous System Infections Has associated chemicals Has associated genes Central Nervous System Viral Diseases Has associated chemicals Has associated genes Encephalitis, Viral Has associated chemicals Has associated genes Leukoencephalopathy, Progressive Multifocal Has associated chemicals Has associated genes
8. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Central Nervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Central Nervous System Infections Has associated chemicals Has associated genes Infectious Encephalitis Has associated chemicals Has associated genes Encephalitis, Viral Has associated chemicals Has associated genes Leukoencephalopathy, Progressive Multifocal Has associated chemicals Has associated genes
9. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Demyelinating Diseases Has associated chemicals Has associated genes Has associated exposure references Leukoencephalopathy, Progressive Multifocal Has associated chemicals Has associated genes

Top ↑ Descendants

None.