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Disease Lichen Planus

Name Lichen Planus
Synonyms Lichen Ruber Planus | Lichen Rubra Planus
Definition An inflammatory, pruritic disease of the skin and mucous membranes, which can be either generalized or localized. It is characterized by distinctive purplish, flat-topped papules having a predilection for the trunk and flexor surfaces. The lesions may be discrete or coalesce to form plaques. Histologically, there is a 'saw-tooth' pattern of epidermal hyperplasia and vacuolar alteration of the basal layer of the epidermis along with an intense upper dermal inflammatory infiltrate composed predominantly of T-cells. Etiology is unknown.
Categories Skin disease
MeSH® ID D008010
External Links

Top ↑ Ancestors

DiseasesSkin and Connective Tissue Diseases Has associated chemicals Has associated genes Has associated exposure references Skin Diseases Has associated chemicals Has associated genes Has associated exposure references Skin Diseases, Papulosquamous Has associated chemicals Has associated genes Lichenoid Eruptions Has associated chemicals Has associated genes Lichen Planus Has associated chemicals Has associated genes

Top ↑ Descendants

Lichen Planus Has associated chemicals Has associated genes
  Lichen Planus, Familial
  Lichen planus follicularis
  Lichen Planus, Oral Has associated chemicals Has associated genes