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Disease Marfan Syndrome

Name Marfan Syndrome
Synonyms Marfan's Syndrome | Marfans Syndrome | Marfan Syndrome, Type I | MFS | MFS1 | Syndrome, Marfan | Syndrome, Marfan's
Definition An autosomal dominant disorder of CONNECTIVE TISSUE with abnormal features in the heart, the eye, and the skeleton. Cardiovascular manifestations include MITRAL VALVE PROLAPSE, dilation of the AORTA, and aortic dissection. Other features include lens displacement (ectopia lentis), disproportioned long limbs and enlarged DURA MATER (dural ectasia). Marfan syndrome is associated with mutations in the gene encoding fibrillin, a major element of extracellular microfibrils of connective tissue.
Categories Cardiovascular disease | Congenital abnormality | Connective tissue disease | Genetic disease (inborn) | Musculoskeletal disease
MeSH® ID D008382
OMIM® ID 154700
External Links

Top ↑ Ancestors

1. DiseasesMusculoskeletal Diseases Has associated chemicals Has associated genes Has associated exposure references Bone Diseases Has associated chemicals Has associated genes Has associated exposure references Bone Diseases, Developmental Has associated chemicals Has associated genes Marfan Syndrome Has associated chemicals Has associated genes
2. DiseasesCardiovascular Diseases Has associated chemicals Has associated genes Has associated exposure references Cardiovascular Abnormalities Has associated chemicals Has associated genes Has associated exposure references Heart Defects, Congenital Has associated chemicals Has associated genes Has associated exposure references Marfan Syndrome Has associated chemicals Has associated genes
3. DiseasesCardiovascular Diseases Has associated chemicals Has associated genes Has associated exposure references Heart Diseases Has associated chemicals Has associated genes Has associated exposure references Heart Defects, Congenital Has associated chemicals Has associated genes Has associated exposure references Marfan Syndrome Has associated chemicals Has associated genes
4. DiseasesCongenital, Hereditary, and Neonatal Diseases and Abnormalities Has associated chemicals Has associated genes Has associated exposure references Congenital Abnormalities Has associated chemicals Has associated genes Has associated exposure references Abnormalities, Multiple Has associated chemicals Has associated genes Marfan Syndrome Has associated chemicals Has associated genes
5. DiseasesCongenital, Hereditary, and Neonatal Diseases and Abnormalities Has associated chemicals Has associated genes Has associated exposure references Congenital Abnormalities Has associated chemicals Has associated genes Has associated exposure references Cardiovascular Abnormalities Has associated chemicals Has associated genes Has associated exposure references Heart Defects, Congenital Has associated chemicals Has associated genes Has associated exposure references Marfan Syndrome Has associated chemicals Has associated genes
6. DiseasesCongenital, Hereditary, and Neonatal Diseases and Abnormalities Has associated chemicals Has associated genes Has associated exposure references Genetic Diseases, Inborn Has associated chemicals Has associated genes Has associated exposure references Marfan Syndrome Has associated chemicals Has associated genes
7. DiseasesSkin and Connective Tissue Diseases Has associated chemicals Has associated genes Has associated exposure references Connective Tissue Diseases Has associated chemicals Has associated genes Has associated exposure references Marfan Syndrome Has associated chemicals Has associated genes

Top ↑ Descendants

Marfan Syndrome Has associated chemicals Has associated genes
  Cutis Laxa-Marfanoid Syndrome
  Furlong syndrome
  Lujan Fryns syndrome Has associated chemicals Has associated genes
  Marfanoid Habitus with Microcephaly and Glomerulonephritis
  Marfanoid Habitus with Situs Inversus
  Marfanoid hypermobility syndrome
  Marfanoid Mental Retardation Syndrome, Autosomal
  Marfan Syndrome type 2
  Shprintzen Golberg craniosynostosis Has associated chemicals Has associated genes