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Disease Movement Disorders

These are exposure studies associated with the disease and all of its children.

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1–22 of 22 results.
  Reference Associated Study Title Author's Summary Study Factors Stressor Receptors Country Medium Exposure Marker Measurements Outcome
1. Kamel F, et al. (2007). Agricultural Health Study (AHS) This study suggests that exposure to certain pesticides may increase Parkinson's disease risk. 2,4,5-Trichlorophenoxyacetic Acid | Benomyl | butylate | Carbon Disulfide | Carbon Tetrachloride | cyanazine | Dicamba | Ethylene Dibromide | Lindane | mancozeb | Maneb | methyl bromide | Paraquat | pendimethalin | Pesticides | Phorate | tetrachloroisophthalonitrile Study subjects | Workers United States Details Agricultural Workers' Diseases | Parkinson Disease
2. Liu R, et al. (2016). Parkinson's Genes and Environment Study (PAGE) Overall, we found limited evidence for an association between exposures to ambient particulate matter PM10, PM2.5, or nitrogen dioxide and Parkinson disease risk; however, the suggestive evidence that exposures to PM2.5 and PM10 may increase disease risk among female never-smokers warrants further investigation. sex | tobacco Air Pollutants Controls for disease:Parkinson Disease | Subjects with disease:Parkinson Disease United States air, ambient Nitrogen Dioxide | Particulate Matter Details Parkinson Disease
3. Kamel F, et al. (2014). Agricultural Health Study (AHS) | Farming and Movement Evaluation Study (FAME) Polyunsaturated fatty acid intake was consistently associated with lower Parkinson's disease (PD) risk, and dietary fats modified the association of PD risk with pesticide exposure. alpha-Linolenic Acid | Fatty Acids | Fatty Acids, Unsaturated | Paraquat | Rotenone Controls for disease:Parkinson Disease | Subjects with disease:Parkinson Disease | Workers United States Details Agricultural Workers' Diseases | Parkinson Disease
4. Ritz B, et al. (2016). We found ambient air pollution from traffic sources to be associated with risk of Parkinson's Disease, with a 9% higher risk (95% CI: 3, 16.0%) per interquartile range increase (2.97 micrograms per cubic meter) in modeled nitrogen dioxide. Carbon Monoxide | Nitric Oxide | Nitrogen Dioxide Controls for disease:Parkinson Disease | Subjects with disease:Parkinson Disease Denmark Carbon Monoxide | Nitric Oxide | Nitrogen Dioxide Details Parkinson Disease
5. Manthripragada AD, et al. (2010). Parkinson's Environment and Genes Study (PEG) The increase in risk we observed among PON1-55 variant carriers for specific organophosphates metabolized by PON1 underscores the importance of considering susceptibility factors when studying environmental exposures in Parkinson disease. genetics Chlorpyrifos | Diazinon | Pesticides Subjects with gene influence:PON1 United States Chlorpyrifos | Diazinon | Pesticides Details Parkinson Disease
6. Louis ED, et al. (2011). Blood harmane and lead concentrations separately correlated with total tremor scores. Participants with high blood concentrations of both toxicants had the highest tremor scores, suggesting an additive effect of these toxicants on tremor severity. harman | Lead Controls for disease:Essential Tremor | Subjects with disease:Essential Tremor United States blood harman | Lead Details Essential Tremor
7. Narayan S, et al. (2015). This study lends support to a previous report that commonly used pesticides, specifically organochlorines and organophosphorous compounds, and variant ABCB1 genotypes at two polymorphic sites jointly increase risk of Parkinson's Disease. genetics Hydrocarbons, Chlorinated | Organophosphorus Compounds | Pesticides Subjects with gene influence:ABCB1 | Workers United States Details Parkinson Disease
8. Weisskopf MG, et al. (2010). Normative Aging Study (NAS) These findings, using an objective biological marker of cumulative lead exposure among typical Parkinson Disease (PD) patients seen in our movement disorders clinics, strengthen the evidence that cumulative exposure to lead increases the risk of PD. Lead Study subjects United States patella | tibia Lead Details Parkinson Disease
9. Ritz BR, et al. (2009). Our population-based case-control study of Parkinson's Disease (PD) conducted in a California population heavily exposed to pesticides replicates and extends evidence for an association between dopamine transporter (DAT) variants and PD and highlights possible interactions of disease-associated DAT susceptibility alleles and pesticide exposure. genetics Maneb | Paraquat Subjects with gene influence:SLC6A3 | Workers United States Details Parkinson Disease
10. Costello S, et al. (2009). This study provides evidence that exposure to a combination of maneb and paraquat increases Parkinson's Disease risk, particularly in younger subjects and/or when exposure occurs at younger ages. age Maneb | Paraquat Study subjects United States Details Parkinson Disease
11. Searles Nielsen S, et al. (2015). Midwestern US Welders Cohort We assessed DNA methylation at three CpG sites in NOS2 gene exon 1 from the blood of 201 welders (exposed to manganese in fumes), and found parkinsonism cases had lower mean NOS2 methylation (specifically at site 8329 in an exonic splicing enhancer). Manganese Workers United States blood NOS2 Details Parkinson Disease, Secondary
12. Kirrane EF, et al. (2015). Agricultural Health Study (AHS) We observed positive associations of Parkinson disease with ozone and fine particulate matter in North Carolina but not in Iowa. Ozone | Particulate Matter Workers United States Details Parkinson Disease
13. Goldman SM, et al. (2012). Agricultural Health Study (AHS) | Farming and Movement Evaluation Study (FAME) The present study tested the hypothesis that the association between paraquat and Parkinson Disease risk is enhanced in those with homozygous deletions of GSTT1 or GSTM1. genetics Paraquat Subjects with gene influence:GSTM1 | Subjects with gene influence:GSTT1 | Workers United States Details Agricultural Workers' Diseases | Parkinson Disease
14. Furlong M, et al. (2015). Farming and Movement Evaluation Study (FAME) Although sample size was limited, protective glove use and hygiene practices appeared to be important modifiers of the association between pesticides and Parkinson disease and may reduce risk of Parkinson disease associated with certain pesticides. Paraquat | Permethrin | Rotenone | Trifluralin Workers United States Details Parkinson Disease
15. Tanner CM, et al. (2011). Agricultural Health Study (AHS) | Farming and Movement Evaluation Study (FAME) Parkinson's Disease (PD) was positively associated with two groups of pesticides defined by mechanisms implicated experimentally-those that impair mitochondrial function and those that increase oxidative stress-supporting a role for these mechanisms in PD pathophysiology. Paraquat | Rotenone Workers United States Details Agricultural Workers' Diseases | Parkinson Disease
16. Chen CY, et al. (2017). Although Particulate Matter(10) plays a significant role in Parkinson Disease development, the associated chemical/metal compounds that are capable of inducing adverse biological mechanisms still warrant further exploration. Particulate Matter Study subjects Taiwan, Province of China Details Parkinson Disease
17. Palacios N, et al. (2014). Nurses' Health Study (NHS) In summary, overall the results of this large cohort study of female nurses do not support an effect of air pollution on Parkinson Disease risk. Particulate Matter Workers United States air Particulate Matter Details Parkinson Disease
18. Kioumourtzoglou MA, et al. (2016). We conducted a large-scale, multi-city study to estimate the impact of long-term particulate matter <=2.5 microns city-wide exposure on city-wide hospital admissions for neurological outcomes, using data from Medicare enrollees in the northeastern United States. Particulate Matter Study subjects United States air Particulate Matter Details Alzheimer Disease | Dementia | Parkinson Disease
19. Paul KC, et al. (2015). We found that organophosphate pesticides were more strongly associated with Parkinson disease among participants with variant genotypes in NOS1, consistent with the importance of oxidative stress-inducing mechanisms. genetics Pesticides Subjects with gene influence:NOS1 | Controls for disease:Parkinson Disease | Subjects with disease:Parkinson Disease United States Details Parkinson Disease
20. Dick FD, et al. (2007). The association of pesticide exposure with Parkinson's disease suggests a causative role; repeated traumatic loss of consciousness is also associated with increased risk. Pesticides Controls for disease:Parkinson Disease | Subjects with disease:Parkinson Disease Italy|Malta|
Romania|Sweden|
United Kingdom
Details
21. Dick FD, et al. (2007). Geoparkinson Study GSTM1 null subjects heavily exposed to solvents appear to be at increased risk of Parkinson's disease. genetics Solvents Subjects with gene influence:GSTM1 United Kingdom Details Parkinson Disease
22. Mao X, et al. (2014). We describe associations among basic characteristics, seasons, and diseases with serum levels of 25-hydroxyvitamin D in patients and note that 25(OH)D3 levels are low while 25(OH)D2 levels are high among patients with lung diseases, dyskinesias, and coronary heart disease, and participants with diabetes and cerebral infarction have higher 25(OH)D3 serum concentrations compared with lung disease patients. age | disease Vitamin D Subjects with disease:Cerebral Infarction | Subjects with disease:Coronary Disease | Subjects with disease:Diabetes Mellitus | Subjects with disease:Dyskinesias | Subjects with disease:Hypertension | Subjects with disease:Lung Diseases | Study subjects China serum 25-Hydroxyvitamin D 2 | 25-hydroxyvitamin D | Calcifediol Details
1–22 of 22 results.