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Disease Multiple Sclerosis

Name Multiple Sclerosis
Synonyms Disseminated Sclerosis | DISSEMINATED SCLEROSIS MULTIPLE SCLEROSIS, SUSCEPTIBILITY TO, 1, INCLUDED | MS | MS1, INCLUDED | MS2 | MS3 | MS4 | MS (Multiple Sclerosis) | Multiple Sclerosis, Acute Fulminating | MULTIPLE SCLEROSIS, SUSCEPTIBILITY TO | MULTIPLE SCLEROSIS, SUSCEPTIBILITY TO, 2 | MULTIPLE SCLEROSIS, SUSCEPTIBILITY TO, 3 | MULTIPLE SCLEROSIS, SUSCEPTIBILITY TO, 4 | Sclerosis, Disseminated | Sclerosis, Multiple
Definition An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
Categories Immune system disease | Nervous system disease
MeSH® ID D009103
OMIM® IDs 126200 | 612594 | 612595 | 612596
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Top ↑ Ancestors

1. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Autoimmune Diseases of the Nervous System Has associated chemicals Has associated genes Has associated exposure references Demyelinating Autoimmune Diseases, CNS Has associated chemicals Has associated genes Has associated exposure references Multiple Sclerosis Has associated chemicals Has associated genes Has associated exposure references
2. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Demyelinating Diseases Has associated chemicals Has associated genes Has associated exposure references Demyelinating Autoimmune Diseases, CNS Has associated chemicals Has associated genes Has associated exposure references Multiple Sclerosis Has associated chemicals Has associated genes Has associated exposure references
3. DiseasesImmune System Diseases Has associated chemicals Has associated genes Has associated exposure references Autoimmune Diseases Has associated chemicals Has associated genes Has associated exposure references Autoimmune Diseases of the Nervous System Has associated chemicals Has associated genes Has associated exposure references Demyelinating Autoimmune Diseases, CNS Has associated chemicals Has associated genes Has associated exposure references Multiple Sclerosis Has associated chemicals Has associated genes Has associated exposure references

Top ↑ Descendants

Multiple Sclerosis Has associated chemicals Has associated genes Has associated exposure references
  Disseminated Sclerosis with Narcolepsy
  Multiple Sclerosis, Chronic Progressive Has associated chemicals Has associated genes
  Multiple Sclerosis, Relapsing-Remitting Has associated chemicals Has associated genes
  Opticospinal Multiple Sclerosis