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Disease Myasthenia Gravis

Name Myasthenia Gravis
Synonyms Generalized Myasthenia Gravis | Myasthenia Gravis, Generalized | Myasthenia Gravis, Ocular | Ocular Myasthenia Gravis
Definition A disorder of neuromuscular transmission characterized by weakness of cranial and skeletal muscles. Autoantibodies directed against acetylcholine receptors damage the motor endplate portion of the NEUROMUSCULAR JUNCTION, impairing the transmission of impulses to skeletal muscles. Clinical manifestations may include diplopia, ptosis, and weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles. THYMOMA is commonly associated with this condition. (Adams et al., Principles of Neurology, 6th ed, p1459)
Categories Immune system disease | Nervous system disease
MeSH® ID D009157
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Top ↑ Ancestors

1. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Autoimmune Diseases of the Nervous System Has associated chemicals Has associated genes Has associated exposure references Myasthenia Gravis Has associated chemicals Has associated genes
2. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Neuromuscular Diseases Has associated chemicals Has associated genes Has associated exposure references Neuromuscular Junction Diseases Has associated chemicals Has associated genes Myasthenia Gravis Has associated chemicals Has associated genes
3. DiseasesImmune System Diseases Has associated chemicals Has associated genes Has associated exposure references Autoimmune Diseases Has associated chemicals Has associated genes Has associated exposure references Autoimmune Diseases of the Nervous System Has associated chemicals Has associated genes Has associated exposure references Myasthenia Gravis Has associated chemicals Has associated genes

Top ↑ Descendants

Myasthenia Gravis Has associated chemicals Has associated genes
  Congenital myasthenic syndrome with episodic apnea Has associated chemicals Has associated genes
  Myasthenia Gravis, Autoimmune, Experimental Has associated chemicals Has associated genes
  Myasthenia Gravis, Neonatal
  Myasthenia Gravis with Thymus Hyperplasia Has associated genes
  Myasthenia, Limb-Girdle, Autoimmune