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Disease Neurofibroma

Name Neurofibroma
Synonym Neurofibromas
Definition A moderately firm, benign, encapsulated tumor resulting from proliferation of SCHWANN CELLS and FIBROBLASTS that includes portions of nerve fibers. The tumors usually develop along peripheral or cranial nerves and are a central feature of NEUROFIBROMATOSIS 1, where they may occur intracranially or involve spinal roots. Pathologic features include fusiform enlargement of the involved nerve. Microscopic examination reveals a disorganized and loose cellular pattern with elongated nuclei intermixed with fibrous strands. (From Adams et al., Principles of Neurology, 6th ed, p1016)
Categories Cancer | Nervous system disease
MeSH® ID D009455
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Top ↑ Ancestors

1. DiseasesNeoplasms Has associated chemicals Has associated genes Has associated exposure references Neoplasms by Histologic Type Has associated chemicals Has associated genes Has associated exposure references Neoplasms, Nerve Tissue Has associated chemicals Has associated genes Has associated exposure references Nerve Sheath Neoplasms Has associated chemicals Has associated genes Has associated exposure references Neurofibroma Has associated chemicals Has associated genes
2. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Nervous System Neoplasms Has associated chemicals Has associated genes Has associated exposure references Peripheral Nervous System Neoplasms Has associated chemicals Has associated genes Has associated exposure references Nerve Sheath Neoplasms Has associated chemicals Has associated genes Has associated exposure references Neurofibroma Has associated chemicals Has associated genes
3. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Neuromuscular Diseases Has associated chemicals Has associated genes Has associated exposure references Peripheral Nervous System Diseases Has associated chemicals Has associated genes Peripheral Nervous System Neoplasms Has associated chemicals Has associated genes Has associated exposure references Nerve Sheath Neoplasms Has associated chemicals Has associated genes Has associated exposure references Neurofibroma Has associated chemicals Has associated genes

Top ↑ Descendants

Neurofibroma Has associated chemicals Has associated genes
  Neurofibroma, Plexiform Has associated chemicals Has associated genes
View node Neurofibromatoses Has associated chemicals Has associated genes
  Neurofibrosarcoma Has associated chemicals Has associated genes