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Disease Papillon-Lefevre Disease

Name Papillon-Lefevre Disease
Synonyms Haim Monk Syndrome | Haim-Monk Syndrome | Keratosis Palmoplantaris with Periodontopathia | Keratosis Palmoplantar Periodontopathies | Keratosis Palmoplantar Periodontopathy | Palmoplantar Periodontopathies, Keratosis | PALS | Papillon Lefevre Disease | Papillon Lefevre Syndrome | Papillon-Lefevre Syndrome | PLS
Definition Rare, autosomal recessive disorder occurring between the first and fifth years of life. It is characterized by palmoplantar keratoderma with periodontitis followed by the premature shedding of both deciduous and permanent teeth. Mutations in the gene for CATHEPSIN C have been associated with this disease.
Categories Genetic disease (inborn) | Skin disease
MeSH® ID D010214
OMIM® ID 245000
External Links

Top ↑ Ancestors

1. DiseasesCongenital, Hereditary, and Neonatal Diseases and Abnormalities Has associated chemicals Has associated genes Has associated exposure references Genetic Diseases, Inborn Has associated chemicals Has associated genes Has associated exposure references Skin Diseases, Genetic Has associated chemicals Has associated genes Has associated exposure references Keratoderma, Palmoplantar Has associated chemicals Has associated genes Papillon-Lefevre Disease Has associated chemicals Has associated genes
2. DiseasesSkin and Connective Tissue Diseases Has associated chemicals Has associated genes Has associated exposure references Skin Diseases Has associated chemicals Has associated genes Has associated exposure references Keratosis Has associated chemicals Has associated genes Has associated exposure references Keratoderma, Palmoplantar Has associated chemicals Has associated genes Papillon-Lefevre Disease Has associated chemicals Has associated genes
3. DiseasesSkin and Connective Tissue Diseases Has associated chemicals Has associated genes Has associated exposure references Skin Diseases Has associated chemicals Has associated genes Has associated exposure references Skin Diseases, Genetic Has associated chemicals Has associated genes Has associated exposure references Keratoderma, Palmoplantar Has associated chemicals Has associated genes Papillon-Lefevre Disease Has associated chemicals Has associated genes

Top ↑ Descendants

Papillon-Lefevre Disease Has associated chemicals Has associated genes
  Keratoderma palmoplantaris transgrediens
  Keratosis palmoplantaris with periodontopathia and onychogryposis Has associated chemicals Has associated genes