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Disease Paralyses, Familial Periodic

Name Paralyses, Familial Periodic
Synonyms Familial Periodic Paralyses | Familial Periodic Paralysis | Normokalemic Periodic Paralyses | Normokalemic Periodic Paralysis | Paralyses, Normokalemic Periodic | Paralysis, Familial Periodic | Paralysis, Normokalemic Periodic | Periodic Paralyses, Familial | Periodic Paralyses, Normokalemic | Periodic Paralysis, Familial | Periodic Paralysis, Normokalemic
Definition A heterogenous group of inherited disorders characterized by recurring attacks of rapidly progressive flaccid paralysis or myotonia. These conditions have in common a mutation of the gene encoding the alpha subunit of the sodium channel in skeletal muscle. They are frequently associated with fluctuations in serum potassium levels. Periodic paralysis may also occur as a non-familial process secondary to THYROTOXICOSIS and other conditions. (From Adams et al., Principles of Neurology, 6th ed, p1481)
Categories Genetic disease (inborn) | Metabolic disease | Musculoskeletal disease | Nervous system disease
MeSH® ID D010245
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Top ↑ Ancestors

1. DiseasesMusculoskeletal Diseases Has associated chemicals Has associated genes Has associated exposure references Muscular Diseases Has associated chemicals Has associated genes Paralyses, Familial Periodic Has associated chemicals Has associated genes
2. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Neuromuscular Diseases Has associated chemicals Has associated genes Has associated exposure references Muscular Diseases Has associated chemicals Has associated genes Paralyses, Familial Periodic Has associated chemicals Has associated genes
3. DiseasesCongenital, Hereditary, and Neonatal Diseases and Abnormalities Has associated chemicals Has associated genes Has associated exposure references Genetic Diseases, Inborn Has associated chemicals Has associated genes Has associated exposure references Metabolism, Inborn Errors Has associated chemicals Has associated genes Has associated exposure references Metal Metabolism, Inborn Errors Has associated chemicals Has associated genes Paralyses, Familial Periodic Has associated chemicals Has associated genes
4. DiseasesNutritional and Metabolic Diseases Has associated chemicals Has associated genes Has associated exposure references Metabolic Diseases Has associated chemicals Has associated genes Has associated exposure references Metabolism, Inborn Errors Has associated chemicals Has associated genes Has associated exposure references Metal Metabolism, Inborn Errors Has associated chemicals Has associated genes Paralyses, Familial Periodic Has associated chemicals Has associated genes

Top ↑ Descendants

Paralyses, Familial Periodic Has associated chemicals Has associated genes
View node Hypokalemic Periodic Paralysis Has associated chemicals Has associated genes
  Normokalemic Periodic Paralysis, Potassium-Sensitive
  Paralysis, Hyperkalemic Periodic Has associated chemicals Has associated genes