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Disease Parasitic Diseases

These phenotypes are associated with Parasitic Diseases or its descendants. A phenotype has an inferred association via a curated chemical interaction or a gene-GO annotation or both.

1–50 of 10,818 results.
  Phenotype Disease Chemical Inference Network Gene Inference Network References
1. cell proliferation Malaria Inferred via 17 chemicals: Amodiaquine | artemisinine | Artesunate | Astemizole | borrelidin | Calcium | Chloroquine | Chlorpromazine | Ciprofloxacin | Cyproheptadine | Hydrazones | Hydroxychloroquine | Imipramine | Pyrimethamine | Quinidine | Testosterone | Tetracycline Inferred via 1 gene: TNF 114
2. cell death Malaria Inferred via 17 chemicals: Amodiaquine | Atovaquone | Calcium | Chloroquine | Chlorpromazine | Dapsone | Doxycycline | halofantrine | Imipramine | Mefloquine | Primaquine | Pyrimethamine | Quinidine | Quinine | Testosterone | Tetracycline | Triazoles   119
3. apoptotic process Malaria Inferred via 12 chemicals: Artesunate | Astemizole | Calcium | Chloroquine | Chlorpromazine | Ciprofloxacin | Doxycycline | Hydroxychloroquine | Imipramine | Pyrimethamine | Quinidine | Testosterone Inferred via 2 genes: LTBR | TNF 118
4. cell proliferation Malaria, Falciparum Inferred via 12 chemicals: Amodiaquine | Artesunate | Chloroquine | Clotrimazole | Copper | Folic Acid | neocuproine | oryzalin | Palmitic Acid | Pyrimethamine | Quinidine | tetrathiomolybdate   62
5. cell death Malaria, Falciparum Inferred via 11 chemicals: Amodiaquine | Atovaquone | Chloroquine | Copper | Dapsone | halofantrine | Mefloquine | Palmitic Acid | Pyrimethamine | Quinidine | Quinine   64
6. cell death Leishmaniasis, Cutaneous Inferred via 11 chemicals: Allopurinol | Amphotericin B | Gentamicins | Indomethacin | Itraconazole | Ketoconazole | mammea A-BB | Omeprazole | Pentamidine | Pentoxifylline | Zinc Sulfate   44
7. apoptotic process Malaria, Falciparum Inferred via 10 chemicals: Artesunate | Chloroquine | Clotrimazole | Copper | Folic Acid | Leucovorin | neocuproine | Palmitic Acid | Pyrimethamine | Quinidine Inferred via 1 gene: FAS 54
8. cell proliferation Leishmaniasis, Cutaneous Inferred via 10 chemicals: Allopurinol | Amphotericin B | Gentamicins | Indomethacin | Itraconazole | Ketoconazole | Omeprazole | Pentoxifylline | Sodium Chloride | Zinc Sulfate Inferred via 1 gene: TNF 52
9. positive regulation of cell death Malaria, Falciparum Inferred via 9 chemicals: Chloroquine | chloroquine diphosphate | Clotrimazole | Copper | Folic Acid | Palmitic Acid | Perhexiline | tetrathiomolybdate | Thioridazine Inferred via 2 genes: FAS | HBB 33
10. response to oxidative stress Malaria Inferred via 9 chemicals: Amodiaquine | Calcium | Chloroquine | Dapsone | Imipramine | Ketotifen | Mefloquine | Quinidine | Testosterone Inferred via 1 gene: G6PD 71
11. apoptotic process Leishmaniasis, Cutaneous Inferred via 8 chemicals: Allopurinol | Gentamicins | Indomethacin | Ketoconazole | Omeprazole | Pentoxifylline | Sodium Chloride | Zinc Sulfate Inferred via 3 genes: IFNG | IL1B | TNF 60
12. membrane lipid catabolic process Leishmaniasis, Cutaneous Inferred via 8 chemicals: Allopurinol | Gentamicins | Indomethacin | Ketoconazole | Omeprazole | Pentoxifylline | Sodium Chloride | Zinc Sulfate   36
13. cell death AIDS-Related Opportunistic Infections Inferred via 8 chemicals: Amphotericin B | amphotericin B, deoxycholate drug combination | Atovaquone | Cidofovir | Dapsone | Pentamidine | Probenecid | Ritonavir   23
14. cell death Ciliophora Infections Inferred via 8 chemicals: Albendazole | Doxycycline | Formaldehyde | malachite green | Niclosamide | Pyrimethamine | Quinacrine | Quinine   15
15. glutathione biosynthetic process Malaria, Falciparum Inferred via 8 chemicals: Amodiaquine | Artesunate | Chloroquine | chloroquine diphosphate | Copper | Folic Acid | Palmitic Acid | Quinidine   25
16. lipid catabolic process Malaria Inferred via 8 chemicals: Artesunate | Calcium | Chloroquine | chloroquine diphosphate | Ciprofloxacin | Doxycycline | Quinidine | Testosterone   60
17. regulation of mitochondrial membrane potential Malaria Inferred via 8 chemicals: Amodiaquine | Atovaquone | Calcium | Chlorpromazine | Ciprofloxacin | Proguanil | Pyrimethamine | Tetracycline   27
18. lipid catabolic process Malaria, Falciparum Inferred via 8 chemicals: Artesunate | Chloroquine | chloroquine diphosphate | Copper | neocuproine | Palmitic Acid | Quinidine | tetrathiomolybdate   24
19. regulation of blood pressure Malaria Inferred via 7 chemicals: Calcium | Chloroquine | Chlorpromazine | Cyproheptadine | Imipramine | Quinidine | Testosterone Inferred via 2 genes: HBB | NOS2 60
20. cell death Leishmaniasis, Visceral Inferred via 7 chemicals: Allopurinol | Amphotericin B | amphotericin B, deoxycholate drug combination | Ketoconazole | Pentamidine | Reactive Oxygen Species | Thalidomide Inferred via 1 gene: HMOX1 47
21. leukocyte chemotaxis Leishmaniasis, Cutaneous Inferred via 7 chemicals: Amphotericin B | Gentamicins | Indomethacin | Itraconazole | Ketoconazole | Omeprazole | Pentoxifylline Inferred via 1 gene: IL10 22
22. cell proliferation Leishmaniasis, Visceral Inferred via 7 chemicals: Allopurinol | Amphotericin B | amphotericin B, deoxycholate drug combination | artemisinine | Ketoconazole | Reactive Oxygen Species | Thalidomide Inferred via 1 gene: TNF 43
23. regulation of mitochondrial membrane potential Malaria, Falciparum Inferred via 7 chemicals: Amodiaquine | Atovaquone | Copper | neocuproine | Proguanil | Pyrimethamine | tetrathiomolybdate   20
24. membrane lipid catabolic process Malaria Inferred via 7 chemicals: Calcium | chloroquine diphosphate | Chlorpromazine | Pyrimethamine | Quinidine | Testosterone | Tetracycline   22
25. response to oxidative stress Malaria, Falciparum Inferred via 7 chemicals: Amodiaquine | Chloroquine | Copper | Dapsone | Mefloquine | Palmitic Acid | Quinidine   41
26. glutathione biosynthetic process Malaria Inferred via 7 chemicals: Amodiaquine | Artesunate | Chloroquine | chloroquine diphosphate | Ciprofloxacin | Quinidine | Testosterone   58
27. cell proliferation Toxoplasmosis Inferred via 7 chemicals: Ciprofloxacin | Cyclophosphamide | Folic Acid | ginsenoside Re | Hydroxychloroquine | oryzalin | Pyrimethamine   30
28. membrane lipid catabolic process Malaria, Falciparum Inferred via 7 chemicals: chloroquine diphosphate | Clotrimazole | Copper | Leucovorin | Pyrimethamine | Quinidine | Thioridazine   21
29. cell proliferation Ciliophora Infections Inferred via 6 chemicals: Albendazole | Formaldehyde | malachite green | Niclosamide | Pyrimethamine | Quinacrine   23
30. apoptotic DNA fragmentation Malaria Inferred via 6 chemicals: Artesunate | Calcium | Chloroquine | Doxycycline | Imipramine | Testosterone   59
31. cell cycle Malaria Inferred via 6 chemicals: Astemizole | Chloroquine | Ciprofloxacin | Pyrimethamine | Quinidine | Quinine   55
32. cell death Leishmaniasis Inferred via 6 chemicals: Amphotericin B | Atovaquone | mammea A-BB | Nelfinavir | Nitric Oxide | Pentamidine   22
33. apoptotic process Toxoplasmosis Inferred via 6 chemicals: Ciprofloxacin | Cyclophosphamide | Folic Acid | ginsenoside Re | Hydroxychloroquine | Pyrimethamine   39
34. cell proliferation Ascariasis Inferred via 6 chemicals: Albendazole | Dichlorvos | Drugs, Chinese Herbal | Fenbendazole | Mebendazole | oxibendazole   10
35. apoptotic process Leishmaniasis, Visceral Inferred via 5 chemicals: Allopurinol | Isosorbide Dinitrate | Ketoconazole | Reactive Oxygen Species | Thalidomide Inferred via 4 genes: HMOX1 | IFNG | IL1B | TNF 39
36. positive regulation of cell death Malaria Inferred via 5 chemicals: borrelidin | Chloroquine | chloroquine diphosphate | Chlorpromazine | Diterpenes, Clerodane Inferred via 3 genes: CD36 | HBB | HP 56
37. positive regulation of apoptotic process Malaria, Falciparum Inferred via 5 chemicals: Chloroquine | Clotrimazole | Copper | Perhexiline | Quinine Inferred via 1 gene: FAS 28
38. response to oxidative stress Leishmaniasis, Cutaneous Inferred via 5 chemicals: Gentamicins | Indomethacin | Pentoxifylline | Sodium Chloride | Zinc Sulfate Inferred via 1 gene: MMP2 19
39. regulation of blood pressure Malaria, Falciparum Inferred via 5 chemicals: Chloroquine | Copper | Folic Acid | Perhexiline | Quinidine Inferred via 1 gene: HBB 20
40. apoptotic process Ciliophora Infections Inferred via 5 chemicals: Doxycycline | Formaldehyde | Niclosamide | Pyrimethamine | Quinacrine   17
41. positive regulation of reactive oxygen species biosynthetic process Malaria, Falciparum Inferred via 5 chemicals: Amodiaquine | Clotrimazole | Copper | Palmitic Acid | Perhexiline   16
42. reactive oxygen species biosynthetic process Malaria, Falciparum Inferred via 5 chemicals: Artesunate | Chloroquine | Copper | neocuproine | Palmitic Acid   19
43. cell proliferation Parasitic Diseases, Animal Inferred via 5 chemicals: Albendazole | Chloroquine | emamectin benzoate | Ivermectin | Quinacrine   19
44. cell cycle Malaria, Falciparum Inferred via 5 chemicals: Chloroquine | Clotrimazole | Pyrimethamine | Quinidine | Quinine   27
45. lipid oxidation Leishmaniasis, Cutaneous Inferred via 5 chemicals: Indomethacin | Omeprazole | Pentoxifylline | Sodium Chloride | Zinc Sulfate   12
46. cell differentiation Malaria Inferred via 5 chemicals: Calcium | Chloroquine | Quinidine | Quinine | Testosterone   51
47. nitric oxide biosynthetic process Leishmaniasis, Cutaneous Inferred via 5 chemicals: Allopurinol | Amphotericin B | Gentamicins | Indomethacin | Omeprazole   15
48. glutathione biosynthetic process Leishmaniasis, Cutaneous Inferred via 5 chemicals: Gentamicins | Indomethacin | Ketoconazole | Omeprazole | Zinc Sulfate   21
49. positive regulation of cell proliferation Malaria, Falciparum Inferred via 5 chemicals: Chloroquine | Clotrimazole | Copper | Folic Acid | tetrathiomolybdate   18
50. cell proliferation AIDS-Related Opportunistic Infections Inferred via 5 chemicals: Amphotericin B | amphotericin B, deoxycholate drug combination | Cidofovir | Probenecid | Ritonavir   15
1–50 of 10,818 results.