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Disease Parkinson Disease

Name Parkinson Disease
Synonyms Idiopathic Parkinson Disease | Idiopathic Parkinson's Disease | Lewy Body Parkinson Disease | Lewy Body Parkinson's Disease | Paralysis Agitans | Parkinson Disease, Idiopathic | Parkinsonism, Primary | Parkinson's Disease | Parkinson's Disease, Idiopathic | Parkinson's Disease, Lewy Body | Primary Parkinsonism
Definition A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
Categories Nervous system disease
MeSH® ID D010300
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Top ↑ Ancestors

1. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Central Nervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Brain Diseases Has associated chemicals Has associated genes Has associated exposure references Basal Ganglia Diseases Has associated chemicals Has associated genes Has associated exposure references Parkinsonian Disorders Has associated chemicals Has associated genes Has associated exposure references Parkinson Disease Has associated chemicals Has associated genes Has associated exposure references
2. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Central Nervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Movement Disorders Has associated chemicals Has associated genes Has associated exposure references Parkinsonian Disorders Has associated chemicals Has associated genes Has associated exposure references Parkinson Disease Has associated chemicals Has associated genes Has associated exposure references
3. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Neurodegenerative Diseases Has associated chemicals Has associated genes Has associated exposure references Parkinson Disease Has associated chemicals Has associated genes Has associated exposure references

Top ↑ Descendants

Parkinson Disease Has associated chemicals Has associated genes Has associated exposure references
  AMYOTROPHIC LATERAL SCLEROSIS-PARKINSONISM/DEMENTIA COMPLEX 1 Has associated chemicals Has associated genes
  Paralysis Agitans, Juvenile, Of Hunt
  Parkinson Disease 10
  Parkinson Disease 11
  PARKINSON DISEASE 11, AUTOSOMAL DOMINANT, SUSCEPTIBILITY TO Has associated chemicals Has associated genes
  Parkinson Disease 12
  Parkinson Disease 13
  PARKINSON DISEASE 13, AUTOSOMAL DOMINANT, SUSCEPTIBILITY TO Has associated chemicals Has associated genes
  PARKINSON DISEASE 14, AUTOSOMAL RECESSIVE Has associated chemicals Has associated genes
  Parkinson Disease 16
  PARKINSON DISEASE 17 Has associated chemicals Has associated genes
  PARKINSON DISEASE 18, AUTOSOMAL DOMINANT, SUSCEPTIBILITY TO Has associated chemicals Has associated genes
  PARKINSON DISEASE 19A, JUVENILE-ONSET Has associated chemicals Has associated genes
  PARKINSON DISEASE 1, AUTOSOMAL DOMINANT Has associated chemicals Has associated genes
  PARKINSON DISEASE 20, EARLY-ONSET Has associated chemicals Has associated genes
  PARKINSON DISEASE 21 Has associated chemicals Has associated genes
  PARKINSON DISEASE 22, AUTOSOMAL DOMINANT Has associated chemicals Has associated genes
  PARKINSON DISEASE 23, AUTOSOMAL RECESSIVE EARLY-ONSET Has associated chemicals Has associated genes
  Parkinson disease 3
  Parkinson Disease 3, Autosomal Dominant Lewy Body
  Parkinson Disease 4, Autosomal Dominant Lewy Body Has associated chemicals Has associated genes
  PARKINSON DISEASE 5, AUTOSOMAL DOMINANT, SUSCEPTIBILITY TO Has associated chemicals Has associated genes
  Parkinson Disease 6, Autosomal Recessive Early-Onset Has associated chemicals Has associated genes
  Parkinson Disease 7, Autosomal Recessive Early-Onset Has associated chemicals Has associated genes
  PARKINSON DISEASE 8, AUTOSOMAL DOMINANT Has associated chemicals Has associated genes
  Parkinson Disease, Familial, Type 1
  PARKINSON DISEASE, LATE-ONSET Has associated chemicals Has associated genes
  Parkinson Disease, Mitochondrial Has associated chemicals Has associated genes
  Parkinsonism-Dystonia, Infantile Has associated chemicals Has associated genes
  Parkinsonism, early onset with mental retardation Has associated chemicals Has associated genes
  Progressive supranuclear palsy atypical Has associated chemicals Has associated genes