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Disease Pathologic Processes

These are exposure studies associated with the disease and all of its children.

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1–50 of 153 results.
  Reference Associated Study Title Author's Summary Study Factors Stressor Receptors Country Medium Exposure Marker Measurements Outcome
1. Choi H, et al. (2008). Prenatal polycyclic aromatic hydrocarbon exposure is likely to contribute to the occurrence of small size for gestational age as well as preterm births among African Americans. 1,12-benzoperylene | 1,2,5,6-dibenzanthracene | benz(a)anthracene | Benzo(a)pyrene | benzo(b)fluoranthene | benzo(k)fluoranthene | chrysene | indeno(1,2,3-cd)pyrene | Polycyclic Aromatic Hydrocarbons Pregnant females United States air 1,12-benzoperylene | 1,2,5,6-dibenzanthracene | benz(a)anthracene | Benzo(a)pyrene | benzo(b)fluoranthene | benzo(k)fluoranthene | chrysene | indeno(1,2,3-cd)pyrene | Polycyclic Aromatic Hydrocarbons Details Fetal Growth Retardation | Premature Birth | Prenatal Exposure Delayed Effects
2. Perry MJ, et al. (2016). Organochlorine exposures measured at age 14 and in adulthood were associated with sperm disomy in this sample of high-exposure men, suggesting that the impacts of persistent pollutants on testicular maturation and function require further investigation. 2,2',3',4,4',5-hexachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | PCB 180 Children | Infants or newborns | Study subjects Faroe Islands blood, cord | serum 2,2',3',4,4',5-hexachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | PCB 180 | Polychlorinated Biphenyls Details Aneuploidy | male meiosis chromosome separation
3. Lopez-Espinosa MJ, et al. (2016). INfancia y Medio Ambiente (INMA) Project To our knowledge, this is the first study to report an association between prenatal exposure to some polychlorinated biphenyls and hexachlorobenzene and fetal growth: abdominal circumference during the first two trimesters of pregnancy, and biparietal diameter and femur length later in pregnancy. 2,2',3',4,4',5-hexachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | Hexachlorobenzene | PCB 180 | Polychlorinated Biphenyls Fetuses | Infants or newborns | Pregnant females Spain blood, cord | serum 2,2',3',4,4',5-hexachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | Hexachlorobenzene | PCB 180 Details Fetal Growth Retardation
4. Casas M, et al. (2015). Children's Health and the Environment in the Faroes | Flemish Environment and Health Survey (FLEHS I) | INfancia y Medio Ambiente (INMA) Project | Norwegian Human Milk Study (HUMIS) | PELAGIE This study suggests that the association between low-level exposure to PCB153 and birth weight exists and follows an inverse linear exposure-response relationship with effects even at low levels, and that maternal smoking and ethnicity modify this association. race | tobacco 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene Fetuses | Infants or newborns | Pregnant females Belgium|Faroe Islands|
France|Germany|
Greece|Greenland|
Norway|Poland|
Slovakia|Spain|
Ukraine
blood | milk, human | plasma, cord | serum | serum, cord 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene Details Birth Weight | Fetal Growth Retardation | Prenatal Exposure Delayed Effects
5. Waggoner JK, et al. (2013). Agricultural Health Study (AHS) In this large cohort of male farmers, pesticide use, in addition to farm machinery use, was associated with fatal injury. 2,4,5-Trichlorophenoxyacetic Acid | 2,4-Dichlorophenoxyacetic Acid | alachlor | butylate | Carbon Disulfide | Carbon Tetrachloride | cyanazine | metribuzin | Paraquat | Ziram Workers United States Details Death
6. Munger R, et al. (1997). We conclude that communities in southern Iowa with drinking water supplies contaminated with herbicides have elevated rates of intrauterine growth retardation compared to neighboring communities with different water supplies. 2,4-Dichlorophenoxyacetic Acid | 2-xylene | 3-xylene | 4-xylene | alachlor | Atrazine | bromodichloromethane | bromoform | chlorodibromomethane | Chloroform | cyanazine | metolachlor | tetrachloroethane Pregnant females United States water, drinking 2,4-Dichlorophenoxyacetic Acid | 2-xylene | alachlor | Atrazine | bromodichloromethane | bromoform | chlorodibromomethane | Chloroform | cyanazine | metolachlor | tetrachloroethane | Xylenes Details Fetal Growth Retardation
7. Pedersen M, et al. (2012). Dietary exposure to acrylamide was associated with reduced birth weight and head circumference. Consumption of specific foods during pregnancy was associated with higher acrylamide exposure in utero diet Acrylamide | Tobacco Smoke Pollution Fetuses | Pregnant females Denmark|Greece|
Norway|Spain|
United Kingdom
blood, cord Acrylamide | Ethylene Oxide | glycidamide Details Birth Weight | Fetal Growth Retardation | Prenatal Exposure Delayed Effects | head development
8. Shirima CP, et al. (2015). We investigated the association between child growth and aflatoxin and fumonisin exposure in Tanzania. Aflatoxins | fumonisin B1 Children Tanzania, United Republic of plasma | urine aflatoxin-albumin adduct | fumonisin B1 Details Growth Disorders
9. López-Abente G, et al. (2012). Statistically significant relative risks for colorectal cancer mortality at a municipal level were detected in the vicinity of mining industry, paper and wood production, food and beverage sector, metal production and processing installations, and ceramics. Air Pollutants Study subjects Spain air, outdoor 1,1,1-trichloroethane | Ammonia | anthracene | Antimony | Arsenicals | Arsenic | Benzene | beta-hexachlorocyclohexane | Cadmium | Cadmium Compounds | Carbon Dioxide | Carbon Monoxide | Carbon Tetrachloride | Chlorine | Chlorine Compounds | Chlorofluorocarbons | Chloroform | Chromium | Chromium Compounds | Cobalt | Diethylhexyl Phthalate | Dioxins | ethylene dichloride | Ethylene Oxide | Fluorine | Fluorine Compounds | Hexachlorobenzene | Hydrogen Cyanide | Lead | Manganese | Manganese Compounds | Mercury | Mercury Compounds | Methane | Methylene Chloride | naphthalene | Nickel | Nitrogen Oxides | Nitrous Oxide | Particulate Matter | Pentachlorophenol | Polychlorinated Biphenyls | Sulfur Oxides | Tetrachloroethylene | Thallium | trichlorobenzene | Trichloroethylene | Vanadium | Vanadium Compounds | Vinyl Chloride | Zinc | Zinc Compounds Details Colorectal Neoplasms | Death
10. Hansell A, et al. (2016). Office for National Statistics Longitudinal Study This large national study suggests that air pollution exposure has long-term effects on mortality that persist decades after exposure, and that historic air pollution exposures influence current estimates of associations between air pollution and mortality. Air Pollutants Study subjects United Kingdom air, ambient Particulate Matter | Soot | Sulfur Dioxide Details Death | Respiratory Tract Diseases
11. Filleul L, et al. (2003). We found a significant association between daily mortality and black smoke among the elderly in Bordeaux. age | sex Air Pollutants Study subjects France air Air Pollutants Details Death
12. Schwartz J, et al. (2017). We conclude that there is a causal association of local air pollution with daily deaths at concentrations below U.S. EPA standards; the estimated attributable risk in Boston exceeded 1,800 deaths during the study period. Air Pollutants Study subjects United States air, ambient Nitrogen Dioxide | Particulate Matter | Soot Details Death
13. Medina-Ramón M, et al. (2008). Worcester Heart Attack Study Residential exposure to traffic-related air pollution increases the mortality risk after hospitalization with acute heart failure. Air Pollutants Subjects with disease:Heart Failure United States Details Death
14. Bentayeb M, et al. (2015). GAZEL Cohort Study We analyzed the association between long-term exposure to air pollution and mortality in a large French cohort (from 1989-2013), and found that long-term exposure to fine particular matter, nitrogen dioxide, sulfur dioxide and benzene is associated with an increased risk of non-accidental mortality. Air Pollutants Study subjects France air, ambient Benzene | Nitrogen Dioxide | Ozone | Particulate Matter | Sulfur Dioxide Details Death
15. Dehbi HM, et al. (2017). National Survey of Health and Development (NSHD) | Southall And Brent Revisited (SABRE) Study We examined associations between air pollution and cardiovascular disease mortality in two British cohorts with over 25 years of follow-up; our results support a detrimental long-term effect for air pollutants on cardiovascular mortality. Air Pollutants Study subjects United Kingdom air, ambient Nitrogen Dioxide | Nitrogen Oxides | Particulate Matter | Smoke | Sulfur Dioxide Details Cardiovascular Diseases | Death
16. César AC, et al. (2015). Even at nitrogen oxides concentrations below the acceptable standard, there is association with deaths caused by respiratory diseases. Air Pollutants Study subjects Brazil air, ambient Carbon Monoxide | Nitrogen Oxides | Ozone | Particulate Matter Details Death | Respiration Disorders
17. Zhang P, et al. (2011). Long-term exposure to ambient air pollution is associated with the death of cardiovascular and cerebrovascular diseases among Chinese populations. The effects of air pollution were more evident in female that in male, and nonsmokers and residents with body mass index less than 18.5 were more vulnerable to outdoor air pollution. body mass index | sex | tobacco Air Pollutants Study subjects China air, ambient Nitrogen Dioxide | Particulate Matter | Sulfur Dioxide Details Cardiovascular Diseases | Cerebrovascular Disorders | Death
18. Zhang F, et al. (2011). Study on the association between ambient air pollution and daily cardiovascular and respiratory mortality in an urban district of Beijing. Air Pollutants Study subjects China air, ambient Nitrogen Dioxide | Particulate Matter | Sulfur Dioxide Details Cardiovascular Diseases | Death | Respiratory Tract Diseases
19. Andersen ZJ, et al. (2012). Danish Diet, Cancer, and Health cohort Study Long-term exposure to traffic-related air pollution may contribute to the development of ischemic but not hemorrhagic stroke, especially severe ischemic strokes leading to death within 30 days. Air Pollutants Study subjects Denmark Nitrogen Dioxide Details Brain Ischemia | Cerebral Hemorrhage | Stroke
20. Ranzi A, et al. (2011). No increased risk of mortality and morbidity was found in the entire area among people living close to incinerators. The internal analysis of the cohort based on dispersion modeling found excesses of mortality for some cancer types in the highest exposure categories, especially in women. People in the highest heavy metal exposure categories tended to have a lower socioeconomic status than those in the lowest categories. The interpretation of the findings is limited given the pilot nature of the study sex | socioeconomic status Air Pollutants Study subjects Italy waste, industrial Cadmium | Dioxins | Mercury | Metals, Heavy | Nitrogen Dioxide | Particulate Matter Details Breast Neoplasms | Colorectal Neoplasms | Death | Liver Neoplasms | Neoplasms | Stomach Neoplasms
21. López-Villarrubia E, et al. (2010). Our findings indicate the existence of a short-term association between current exposure levels to air pollutants and total mortality as well as mortality due to heart and respiratory diseases in both Canary cities studied along with evidence that the association on a given day may spread over several successive days. Air Pollutants Spain air Carbon Monoxide | Nitrogen Dioxide | Ozone | Particulate Matter | Sulfur Dioxide Details Death | Heart Diseases | Respiratory Tract Diseases
22. Zúñiga J, et al. (2016). There could be an association between the air pollution in Panama City (Panama) and an increase in cardiovascular and respiratory mortality. Air Pollutants | Nitrogen Dioxide | Ozone | Particulate Matter Study subjects Panama air, ambient Nitrogen Dioxide | Ozone | Particulate Matter Details Cardiovascular Diseases | Death | Respiratory Tract Diseases
23. Penn SL, et al. (2017). Our findings reinforce the importance of pollutant-specific, location-specific, and source-specific models of health impacts in design of health-risk minimizing emissions control policies. Air Pollutants | Nitrogen Oxides | Particulate Matter | Sulfur Dioxide | Volatile Organic Compounds Study subjects United States air Nitrogen Oxides | Particulate Matter | Sulfur Dioxide | Volatile Organic Compounds Details Death
24. Pope CA 3RD, et al. (2011). American Cancer Society Cancer Prevention Study II (ACS CPS-II) The exposure-response relationship associated with PM2.5 is qualitatively different for lung cancer versus cardiovascular mortality. At low exposure levels, cardiovascular deaths are projected to account for most of the burden of disease, whereas at high levels of PM2.5, lung cancer becomes proportionately more important. tobacco Air Pollutants | Particulate Matter Study subjects United States cigarette Particulate Matter Details Cardiovascular Diseases | Death | Lung Neoplasms
25. Pearce MS, et al. (2012). Particulate Matter and Perinatal Events Research (PAMPER) Association was observed between socio-economic deprivation and particulate matter on birth weight, with increasing effects of particulate matter in reducing birth weight seen with increasing socio-economic disadvantage. socioeconomic status Air Pollutants | Particulate Matter Fetuses | Pregnant females United Kingdom air Particulate Matter Details Birth Weight | Fetal Growth Retardation
26. Goodman PG, et al. (2004). We assessed the associations of particulate pollution (black smoke) and temperature with age-standardized daily mortality rates over 17 years in Dublin, Ireland, using a polynomial distributed lag model of both temperature and particulate air pollution simultaneously through 40 days after exposure. Air Pollutants | Particulate Matter | Smoke Study subjects Ireland air Smoke Details Cardiovascular Diseases | Death | Respiratory Tract Diseases
27. Stevens GA, et al. (2008). In this study, we used data on exposure to 3 major environmental risks (unsafe water and sanitation, indoor air pollution from household solid fuel use, and ambient urban PM pollution) and on cause-specific mortality at the county level in Mexico to estimate the mortality effects of these 3 risks at the county level. socioeconomic status Air Pollutants | Particulate Matter | Water Pollutants Study subjects Mexico Details Death
28. Higuchi K, et al. (2012). This study showed that Mt. Sakurajima's volcanic activities increased the mortality of lung cancer and chronic obstructive pulmonary diseases in the Sakurajima-Tarumizu area, which has the largest amount of ashfall from the volcano in its vicinity. Air Pollutants | Silicon Dioxide Study subjects Japan Air Pollutants | Silicon Dioxide Details Death | Lung Neoplasms | Pulmonary Disease, Chronic Obstructive | Respiration Disorders
29. Monrad M, et al. (2017). Danish Diet, Cancer, and Health cohort Study We found long-term residential traffic-related air pollution to be associated with higher risk of atrial fibrillation. Air Pollutants | Vehicle Emissions Study subjects Denmark air, ambient Nitrogen Dioxide | Nitrogen Oxides Details Atrial Fibrillation
30. Zhang W, et al. (1994). We report early health effects and biological monitoring in persons occupationally exposed to tetraethyl lead in China for the years 1990-1992, including for gasoline depot workers and traffic police officers. Air Pollutants, Occupational | Tetraethyl Lead Workers China air, ambient | urine diethyllead | Lead | triethyllead Details Bradycardia | Tremor
31. Wu M, et al. (2010). These findings confirm the previously reported association between World Trade Center dust exposure and bronchiolar and interstitial lung disease. Aluminum Silicates | Asbestos, Serpentine | Calcium Sulfate | Magnesium Silicates | Nanotubes, Carbon Workers United States lung Aluminum Silicates | Asbestos, Serpentine | Calcium Sulfate | Magnesium Silicates | Nanotubes, Carbon Details Bronchiolitis | Fibrosis | Metaplasia | Pneumonia
32. Wade TJ, et al. (2009). This is the first study to document increased arsenic-associated mortality in the Bayingnormen Inner Mongolia region of China. Arsenic Study subjects China water Arsenic Details Coronary Disease | Death | Neoplasms
33. Paul S, et al. (2014). We infer that arsenic biotransformation leads to promoter hypomethylation of ERCC2, which in turn inhibits the normal functioning of the Cdk-activating kinase complex, thus affecting DNA repair; this effect was highest among the arsenic exposed individuals with dermatological lesions. Arsenic Controls for disease:Skin Diseases | Subjects with disease:Skin Diseases | Study subjects India blood | hair | leukocyte, mononuclear | nail | urine | water, drinking Arsenic | CDK7 | ERCC2 Details Micronuclei, Chromosome-Defective | Skin Diseases | positive regulation of DNA repair
34. Cui N, et al. (2016). Long-term exposure to arsenic is associated with upregulated mRNA expression for genes AHR and CYP1A1 in the blood, and blood CYP1A1 mRNA (but not AHR mRNA) is associated with prolonged corrected QT interval. diet Arsenic Study subjects China blood | water, drinking AHR | Arsenic | CYP1A1 Details Long QT Syndrome | regulation of heart rate
35. Thurston GD, et al. (2016). American Cancer Society Cancer Prevention Study II (ACS CPS-II) Long-term fine particulate matter (PM2.5) exposures from fossil fuel combustion, especially coal burning but also from diesel traffic, were associated with increases in ischemic heart disease mortality in this nationwide population. Arsenic | Carbon | Chlorine | Iron | Lead | Manganese | Particulate Matter | Potassium | Selenium | Silicon | Soot | Sulfur Study subjects United States air, ambient | soil Arsenic | Calcium | Carbon | Chlorine | Iron | Lead | Manganese | Nickel | Particulate Matter | Potassium | Selenium | Silicon | Sodium | Soot | Sulfur | Vanadium | Zinc Details Death | Myocardial Ischemia
36. Keil AP, et al. (2017). Lee-Fraumeni Cohort Our analyses suggest that the excess deaths from causes other than respiratory cancers comprise the majority of the excess deaths caused by inhaled arsenic exposure. arsenic trioxide Workers United States air arsenic trioxide Details Death | Heart Diseases | Respiratory Tract Neoplasms
37. Christensen BC, et al. (2008). Our data suggest that patient survival is associated with asbestos fiber burden in malignant pleural mesothelioma and is perhaps modified by susceptibility. sex Asbestos Subjects with disease:Mesothelioma, Malignant United States lung Asbestos Details Death
38. Kukkonen MK, et al. (2014). Our results support the hypothesis that the inflammasome is important in the development of fibrotic lung disease by associating the NLRP3 rs35829419 variant allele with increased risk of asbestos-related interstitial lung fibrosis, and the TGFB1 rs2241718 variant allele with decreased risk of asbestos-related visceral pleural fibrosis; polymorphisms in CARD8 and TIMP2 are proposed to modify the development and/or calcification of pleural thickenings. genetics Asbestos Subjects with gene influence:CARD8 | Subjects with gene influence:NLRP3 | Subjects with gene influence:TGFB1 | Subjects with gene influence:TIMP2 | Workers Finland Details Asbestosis | Calcinosis | Fibrosis | Occupational Diseases | Pleural Diseases
39. Farr SL, et al. (2004). Agricultural Health Study (AHS) Our findings, along with results from toxicology studies, suggest that use of certain hormonally active pesticides may affect menstrual cycles. Atrazine | Carbamates | Herbicides | Insecticides | Lindane | mancozeb | Maneb | Pesticides Study subjects United States Details Agricultural Workers' Diseases | Menstruation Disturbances | menstrual cycle
40. Yang JH, et al. (2012). National Health and Nutrition Examination Survey (NHANES) The current study suggests that the background exposure to some organochlorine pesticides leads to vitamin D deficiency in humans. beta-hexachlorocyclohexane | DDT | Dichlorodiphenyl Dichloroethylene | Dieldrin | Hexachlorobenzene | nonachlor | oxychlordane Controls for disease:Chronic Disease | Subjects with disease:Chronic Disease | Study subjects United States serum 25-hydroxyvitamin D | beta-hexachlorocyclohexane | DDT | Dichlorodiphenyl Dichloroethylene | Dieldrin | Hexachlorobenzene | nonachlor | oxychlordane Details Vitamin D Deficiency
41. Lo SH, et al. (2006). The acute transient hematologic effects observed in residents exposed to fire extinguisher gas were most likely caused by a small amount of pyrolytic products, probably phosgene; nine months after the exposure, there was a significant improvement without any specific treatment. bromochlorodifluoromethane | bromotrifluoromethane | dichlorodifluoromethane | Phosgene Study subjects Taiwan, Province of China Details Hemolysis | erythrocyte homeostasis
42. Infante-Rivard C. (2004). These findings suggest that exposure to trihalomethanes at the highest levels can affect fetal growth but only in genetically susceptible newborns. genetics bromodichloromethane | bromoform | chlorodibromomethane | Chloroform | Trihalomethanes Subjects with gene influence:CYP2E1 | Controls for disease:Fetal Growth Retardation | Subjects with disease:Fetal Growth Retardation | Infants or newborns | Mothers | Subjects with gene influence:MTHFR Canada bromodichloromethane | bromoform | chlorodibromomethane | Chloroform | Trihalomethanes Details Fetal Growth Retardation | Prenatal Exposure Delayed Effects
43. Nishijo M, et al. (2006). Renal tubular dysfunction induced by Cd affected the causes of death, and mortality for heart failure, cerebral infarction, and nephritis and nephrosis was increased among inhabitants living in a Cd polluted area in Japan. Cadmium Study subjects Japan urine B2M Details Death | Kidney Diseases
44. Adams SV, et al. (2012). National Health and Nutrition Examination Survey (NHANES) Cadmium appears to be associated with overall cancer mortality in men and women, but the specific cancers associated differ between men and women. sex Cadmium Study subjects United States urine Cadmium Details Death | Leukemia | Lung Neoplasms | Lymphoma, Non-Hodgkin | Neoplasms | Ovarian Neoplasms | Pancreatic Neoplasms | Uterine Neoplasms
45. Tellez-Plaza M, et al. (2012). National Health and Nutrition Examination Survey (NHANES) We found strongly suggestive evidence that cadmium, at substantially low levels of exposure, remains an important determinant of all-cause and cardiovascular disease mortality in a representative sample of U.S. adults. tobacco Cadmium Study subjects United States blood | urine Cadmium Details Cardiovascular Diseases | Death
46. Kippler M, et al. (2012). We found evidence of a sex difference in the association between maternal cadmium exposure and birth size, which was apparent only in girls. sex Cadmium Fetuses | Pregnant females Bangladesh urine Cadmium Details Birth Weight | Fetal Growth Retardation
47. Maruzeni S, et al. (2014). In the Cd-exposed residents in the Jinzu River basin, the prevalence of subjects with glucoproteinuria was 4.7% in men and 6.7% in women and much higher than that in controls (0.9% in men, and 0.5% in women), suggesting that environmental Cadmium exposure increased the number of renal tubular dysfunction cases indicated by glucoproteinuria and characterized by an unfavorable long-term life prognosis. Cadmium Study subjects Japan urine Details Death | Glycosuria | Kidney Diseases
48. Menke A, et al. (2009). National Health and Nutrition Examination Survey (NHANES) Environmental cadmium exposure was associated with an increased risk of all-cause, cancer, and cardiovascular disease mortality among men, but not among women. age | tobacco Cadmium Study subjects United States urine Cadmium Details Cardiovascular Diseases | Death | Neoplasms
49. Nawrot TS, et al. (2008). Cadmium in Belgium Study (CadmiBel) The key finding of our study was that in exclusively environmentally exposed subjects, the internal dose of cadmium predicted total and noncardiovascular mortality. Cadmium Controls for disease:Death | Subjects with disease:Death | Study subjects Belgium blood | urine Cadmium | Creatinine Details Death
50. Hyder O, et al. (2013). National Health and Nutrition Examination Survey (NHANES) Environmental cadmium exposure was associated with hepatic necroinflammation, non-alcoholic fatty liver disease, and non-alcoholic steatohepatitis in men, and hepatic necroinflammation in women. age | race | sex Cadmium Study subjects United States urine Cadmium Details Death | Liver Diseases | Non-alcoholic Fatty Liver Disease | inflammatory response | necrotic cell death
1–50 of 153 results.