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Disease Prostatic Diseases

These are exposure studies associated with the disease and all of its children.

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1–30 of 30 results.
  Reference Associated Study Title Author's Summary Study Factors Stressor Receptors Country Medium Exposure Marker Measurements Outcome
1. Koutros S, et al. (2011). Agricultural Health Study (AHS) We evaluated pesticide-single nucleotide polymorphism (SNP) interactions between 45 pesticides and 1913 xenobiotic metabolic enzyme SNPs with respect to prostrate cancer among 776 cases and 1444 controls in the Agricultural Health Study. genetics 2,4,5-Trichlorophenoxyacetic Acid | Carbaryl | Diazinon | Dieldrin | Fonofos | Hexachlorocyclohexane | methyl bromide | Petroleum | Phorate | terbufos Subjects with gene influence:GCLC | Workers United States Details Agricultural Workers' Diseases | Prostatic Neoplasms
2. Chamie K, et al. (2008). Individuals who were exposed to Agent Orange had an increased incidence of prostate cancer, developed the disease at a younger age, and had a more aggressive variant than their unexposed counterparts. Agent Orange | Defoliants, Chemical Veterans United States Details Prostatic Neoplasms
3. Zafar MB, et al. (2001). Agent Orange may have a role in the causation of some types of cancer but we identified no significant relationship of prostate cancer with Agent Orange exposure in patients referred for prostate biopsy. Agent Orange | Defoliants, Chemical Veterans United States Details Prostatic Neoplasms
4. Christensen CH, et al. (2016). Agricultural Health Study (AHS) In this case-control study nested within the Agricultural Health Study cohort, we evaluated evidence of statistical interaction between pesticide exposure and single nucleotide polymorphisms in genes involved in steroid hormone signaling, metabolism, or regulation with the risk of prostate cancer. genetics alachlor | butylate | Carbaryl | Dicamba | Fonofos | Malathion | terbufos Subjects with gene influence:ESR1 | Subjects with gene influence:HSD17B4 | Subjects with gene influence:SHBG | Subjects with gene influence:SRD5A1 | Subjects with gene influence:SULT2A1 | Workers United States Details Prostatic Neoplasms
5. Koutros S, et al. (2013). Agricultural Health Study (AHS) In this analysis, we observed significant increases in the risk of aggressive prostate cancer associated with 4 insecticides: fonofos (organophosphate), malathion (organophosphate), terbufos (organophosphate), and aldrin (organochlorine). Aldrin | Fonofos | Malathion | terbufos Workers United States Details Agricultural Workers' Diseases | Prostatic Neoplasms
6. Koutros S, et al. (2013). Agricultural Health Study (AHS) We observed four quantitative interactions between genome-wide association studies loci and select pesticide use and risk of prostate cancer. genetics Aldrin | Malathion Subjects with gene influence:EHBP1 | Subjects with gene influence:TET2 | Workers United States Details Prostatic Neoplasms
7. Loeb S, et al. (2015). Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Trial This study suggests that selenium supplements may reduce genetic risk of advanced prostate cancer, whereas aspirin, ibuprofen, and vegetables may reduce genetic risk of nonadvanced prostate cancer. genetics Aspirin | Ibuprofen | Selenium Controls for disease:Prostatic Neoplasms | Subjects with disease:Prostatic Neoplasms United States Details Prostatic Neoplasms
8. Freeman LE, et al. (2011). Agricultural Health Study (AHS) In this report, we extend a previous Agricultural Health Study analysis of cancer risk associated with self-reported atrazine use with six additional years of follow-up and more than twice as many cancer cases. Atrazine Workers United States Details Breast Neoplasms | Leukemia | Lymphoma, Non-Hodgkin | Neoplasms | Ovarian Neoplasms | Prostatic Neoplasms | Thyroid Neoplasms
9. Andreotti G, et al. (2012). Agricultural Health Study (AHS) In this nested case-control study, we evaluated the interaction between pesticide use and single nucleotide polymorphisms in genes related to lipid metabolism. genetics Atrazine | Carbofuran | EPTC | Fonofos | glyphosate | Petroleum | terbufos Subjects with gene influence:A4GALT | Subjects with gene influence:ABCG8 | Subjects with gene influence:ACSL5 | Subjects with gene influence:ADIPOR1 | Subjects with gene influence:ALOX15 | Subjects with gene influence:ALOX5AP | Subjects with gene influence:ALOX5 | Subjects with gene influence:ALOXE3 | Subjects with gene influence:LDLR | Subjects with gene influence:LRP1 | Subjects with gene influence:SEC14L2 | Workers United States Details Prostatic Neoplasms
10. Karami S, et al. (2013). Agricultural Health Study (AHS) In this study, genetic variations in vitamin D pathway genes, particularly GC rs7041, a single nucleotide polymorphism previously linked to lower circulating vitamin D levels, modified pesticide associations with prostate cancer risk. genetics Atrazine | metribuzin | Parathion | Petroleum | terbufos Subjects with gene influence:GC | Subjects with gene influence:RXRA | Subjects with gene influence:RXRB | Subjects with gene influence:VDR | Workers United States Details Agricultural Workers' Diseases | Prostatic Neoplasms
11. Lynch SM, et al. (2009). Agricultural Health Study (AHS) We examined butylate use and cancer risk more broadly in the Agricultural Health Study, a cohort of licensed pesticide applicators in Iowa and North Carolina. butylate Workers United States Details Agricultural Workers' Diseases | Hematologic Neoplasms | Lymphoma, Non-Hodgkin | Prostatic Neoplasms
12. Alavanja MC, et al. (2003). Agricultural Health Study (AHS) Use of chlorinated pesticides among applicators over 50 years of age and methyl bromide use were significantly associated with prostate cancer risk. age butylate | Chlorpyrifos | Coumaphos | Fonofos | methyl bromide | Permethrin | Phorate Workers United States Details Agricultural Workers' Diseases | Prostatic Neoplasms
13. Barry KH, et al. (2012). Agricultural Health Study (AHS) Although we did not observe highly significant nucleotide excision repair (NER) single-nucleotide polymorphism (SNP) main effects, our interaction findings between SNPs tagging ERCC1 and CDK7 and fonofos and carbofuran, respectively, suggest the importance of the NER pathway in prostate cancer risk in the presence of certain pesticide exposures. genetics Carbofuran | Dichlorvos | Fonofos | Parathion | Petroleum Subjects with gene influence:CDK7 | Subjects with gene influence:DDB2 | Subjects with gene influence:ERCC1 | Subjects with gene influence:ERCC4 | Workers | Subjects with gene influence:XAB2 United States Details Agricultural Workers' Diseases | Prostatic Neoplasms
14. Multigner L, et al. (2016). We review the findings of various, previous epidemiological studies conducted in the French West Indies to assess the impact of environmental exposure to chlordecone on the health of the population. Chlordecone Infants or newborns | Mothers | Pregnant females | Subjects with disease:Prostatic Neoplasms | Workers Guadeloupe blood | blood, cord | colostrum | milk, human | plasma | subcutaneous fat, abdominal Chlordecone Details Infertility, Male | Prostatic Neoplasms
15. Christensen CH, et al. (2010). Agricultural Health Study (AHS) We observed an increased risk of prostate cancer in association with coumaphos exposure among men with a family history of prostate cancer but not among men without a family history in both early (1993-1999) and later periods in cohort follow-up (2000-2005), although the interaction rate ratio in the early period is stronger than in the later period. genetics Coumaphos Workers United States Details Prostatic Neoplasms
16. Koutros S, et al. (2010). Agricultural Health Study (AHS) In this study we evaluated the interaction between pesticide use, genetic variation on chromosome 8q24, and risk of prostate cancer in 2,220 Agricultural Health Study subjects. genetics Coumaphos | Fonofos | Permethrin | Phorate | terbufos Workers United States Details Prostatic Neoplasms
17. Lynch SM, et al. (2006). Agricultural Health Study (AHS) We did not find any clear, consistent associations between cyanazine exposure and any cancer analyzed. cyanazine Workers United States Details Colonic Neoplasms | Hematologic Neoplasms | Lung Neoplasms | Lymphoma, Non-Hodgkin | Neoplasms | Prostatic Neoplasms
18. Jones RR, et al. (2015). Agricultural Health Study (AHS) Our updated evaluation of diazinon provides additional evidence of an association with lung cancer risk; newly identified links to kidney cancer and associations with aggressive prostate cancer require further evaluation. Diazinon Workers United States Details Agricultural Workers' Diseases | Kidney Neoplasms | Lung Neoplasms | Prostatic Neoplasms
19. Mahajan R, et al. (2006). Agricultural Health Study (AHS) In this study we evaluated cumulative lifetime fonofos exposure until enrollment as a risk factor for incident cancer occurring between the end of enrollment through 2002. genetics Fonofos Workers United States Details Leukemia | Prostatic Neoplasms
20. Barry KH, et al. (2011). Agricultural Health Study (AHS) In this nested case-control study of white male pesticide applicators within the Agricultural Health Study cohort, we observed notable interactions between several pesticides and base excision repair gene variants with respect to prostate cancer. genetics Fonofos Subjects with gene influence:NEIL3 | Workers United States Details Agricultural Workers' Diseases | Prostatic Neoplasms
21. Barry KH, et al. (2012). Agricultural Health Study (AHS) In summary, in this population of primarily white male private applicators in the Agricultural Health Study with follow-up from 1993 through 2007, we observed little evidence of associations between methyl bromide and most cancers examined; however, there were small numbers of exposed cases for many sites. methyl bromide Workers United States Details Agricultural Workers' Diseases | Prostatic Neoplasms | Stomach Neoplasms
22. Cockburn M, et al. (2011). This study provides evidence of an association between prostate cancer and ambient pesticide exposures in and around homes in intensely agricultural areas. The associations appear specific to compounds with a plausible biologic role in prostate carcinogenesis. methyl bromide Study subjects United States Details Prostatic Neoplasms
23. Hou L, et al. (2006). Agricultural Health Study (AHS) We did not find a clear association of lifetime pendimethalin exposure either with overall cancer incidence or with specific cancer sites. pendimethalin Workers United States Details Colorectal Neoplasms | Hematologic Neoplasms | Lymphoma, Non-Hodgkin | Melanoma | Neoplasms | Prostatic Neoplasms
24. Rusiecki JA, et al. (2009). Agricultural Health Study (AHS) In this study we evaluated the incidence of cancer among pesticide applicators exposed to permethrin in the Agricultural Health Study (AHS). Permethrin Workers United States Details Colonic Neoplasms | Leukemia | Lung Neoplasms | Lymphoma, Non-Hodgkin | Melanoma | Multiple Myeloma | Neoplasms | Prostatic Neoplasms | Rectal Neoplasms
25. Belpomme D, et al. (2009). Our study leads to the conclusion that the growing incidence of prostate cancer in Martinique and Guadeloupe suggests that environmental factors such as the intensive and prolonged exposure to pesticides may cause prostate cancer. Pesticides Children | Study subjects Martinique adipose tissue alpha-hexachlorocyclohexane | beta-hexachlorocyclohexane | DDT | Dichlorodiphenyl Dichloroethylene | Hexachlorocyclohexane Details Prostatic Neoplasms
26. Mahajan R, et al. (2006). Agricultural Health Study (AHS) The observed statistical interaction suggests a gene-environment interaction between family history and phorate exposure in the incidence of prostate cancer, but other explanations are also possible. Phorate Workers United States Details Neoplasms | Prostatic Neoplasms
27. Bonner MR, et al. (2010). Agricultural Health Study (AHS) In summary, there was some suggestion that cancers of the prostate and lung as well as leukemia and non-Hodgkin lymphoma may be associated with terbufos use. terbufos Workers United States Details Leukemia | Lung Neoplasms | Lymphoma, Non-Hodgkin | Prostatic Neoplasms
28. Gupta A, et al. (2006). Tetrachlorodibenzodioxin exposure at general population levels is associated with a decreasing risk of benign prostatic hyperplasia with higher exposure levels; tetrachlorodibenzodioxin exposure is also negatively associated with serum testosterone levels. Tetrachlorodibenzodioxin Veterans United States serum Tetrachlorodibenzodioxin Details Prostatic Hyperplasia | testosterone biosynthetic process
29. Mozzachio AM, et al. (2008). Agricultural Health Study (AHS) Chlorothalonil was not associated with overall cancer incidence, nor did we find any association with colon, lung, and prostate cancers - the only cancers for which we had sufficient numbers to explore associations. tetrachloroisophthalonitrile Workers United States Details Colonic Neoplasms | Lung Neoplasms | Neoplasms | Prostatic Neoplasms
30. Wagner SE, et al. (2009). Increased prostate cancer rates were associated with reduced soil zinc concentrations and elevated groundwater use, although this observation is not likely to contribute to South Carolina's racial prostate cancer disparity. Zinc Subjects with disease:Prostatic Neoplasms United States soil Zinc Details Prostatic Neoplasms
1–30 of 30 results.