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Disease Sarcoma, Kaposi

Name Sarcoma, Kaposi
Synonyms Kaposi Sarcoma | KAPOSI SARCOMA, SUSCEPTIBILITY TO | Kaposi's Sarcoma | Kaposis Sarcoma | MCD, INCLUDED | Multiple Idiopathic Pigmented Hemangiosarcoma | MULTIPLE IDIOPATHIC PIGMENTED HEMANGIOSARCOMA, SUSCEPTIBILITY TO MULTICENTRIC CASTLEMAN DISEASE, SUSCEPTIBILITY TO, INCLUDED | Sarcoma, Kaposi's
Definition A multicentric, malignant neoplastic vascular proliferation characterized by the development of bluish-red cutaneous nodules, usually on the lower extremities, most often on the toes or feet, and slowly increasing in size and number and spreading to more proximal areas. The tumors have endothelium-lined channels and vascular spaces admixed with variably sized aggregates of spindle-shaped cells, and often remain confined to the skin and subcutaneous tissue, but widespread visceral involvement may occur. Kaposi's sarcoma occurs spontaneously in Jewish and Italian males in Europe and the United States. An aggressive variant in young children is endemic in some areas of Africa. A third form occurs in about 0.04% of kidney transplant patients. There is also a high incidence in AIDS patients. (From Dorland, 27th ed & Holland et al., Cancer Medicine, 3d ed, pp2105-7) HHV-8 is the suspected cause.
Categories Cancer | Viral disease
MeSH® ID D012514
OMIM® ID 148000
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Top ↑ Ancestors

1. DiseasesVirus Diseases Has associated chemicals Has associated genes Has associated exposure references DNA Virus Infections Has associated chemicals Has associated genes Has associated exposure references Herpesviridae Infections Has associated chemicals Has associated genes Has associated exposure references Sarcoma, Kaposi Has associated chemicals Has associated genes
2. DiseasesNeoplasms Has associated chemicals Has associated genes Has associated exposure references Neoplasms by Histologic Type Has associated chemicals Has associated genes Has associated exposure references Neoplasms, Connective and Soft Tissue Has associated chemicals Has associated genes Has associated exposure references Sarcoma Has associated chemicals Has associated genes Has associated exposure references Sarcoma, Kaposi Has associated chemicals Has associated genes
3. DiseasesNeoplasms Has associated chemicals Has associated genes Has associated exposure references Neoplasms by Histologic Type Has associated chemicals Has associated genes Has associated exposure references Neoplasms, Vascular Tissue Has associated chemicals Has associated genes Has associated exposure references Sarcoma, Kaposi Has associated chemicals Has associated genes

Top ↑ Descendants

Sarcoma, Kaposi Has associated chemicals Has associated genes
  AIDS-related Kaposi sarcoma Has associated chemicals Has associated genes
  Kaposiform Hemangioendothelioma
  Non-AIDS-related Kaposi sarcoma