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Disease Scleroderma, Systemic

Name Scleroderma, Systemic
Synonyms Sclerosis, Systemic | Systemic Scleroderma | Systemic Sclerosis
Definition A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA.
Categories Connective tissue disease | Skin disease
MeSH® ID D012595
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Top ↑ Ancestors

1. DiseasesSkin and Connective Tissue Diseases Has associated chemicals Has associated genes Has associated exposure references Connective Tissue Diseases Has associated chemicals Has associated genes Has associated exposure references Scleroderma, Systemic Has associated chemicals Has associated genes Has associated exposure references
2. DiseasesSkin and Connective Tissue Diseases Has associated chemicals Has associated genes Has associated exposure references Skin Diseases Has associated chemicals Has associated genes Has associated exposure references Scleroderma, Systemic Has associated chemicals Has associated genes Has associated exposure references

Top ↑ Descendants

Scleroderma, Systemic Has associated chemicals Has associated genes Has associated exposure references
  Juvenile-onset scleroderma
  Juvenile systemic scleroderma
  REYNOLDS SYNDROME Has associated chemicals Has associated genes
  Scleroderma, Diffuse Has associated chemicals Has associated genes
  SCLERODERMA, FAMILIAL PROGRESSIVE
View node Scleroderma, Limited Has associated chemicals Has associated genes