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Disease Shwartzman Phenomenon

Name Shwartzman Phenomenon
Synonyms Phenomenon, Schwartzman | Phenomenon, Shwartzman | Schwartzman Phenomenon | Schwartzman Reaction | Schwartzman Reactions | Shwartzman Reaction
Definition Hemorrhagic necrosis that was first demonstrated in rabbits with a two-step reaction, an initial local (intradermal) or general (intravenous) injection of a priming endotoxin (ENDOTOXINS) followed by a second intravenous endotoxin injection (provoking agent) 24 h later. The acute inflammation damages the small blood vessels. The following intravascular coagulation leads to capillary and venous THROMBOSIS and NECROSIS. Shwartzman phenomenon can also occur in other species with a single injection of a provoking agent, and during infections or pregnancy. Its susceptibility depends on the status of IMMUNE SYSTEM, coagulation, FIBRINOLYSIS, and blood flow.
Categories Blood disease | Cardiovascular disease
MeSH® ID D012790
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Top ↑ Ancestors

1. DiseasesCardiovascular Diseases Has associated chemicals Has associated genes Has associated exposure references Vascular Diseases Has associated chemicals Has associated genes Has associated exposure references Hemostatic Disorders Has associated chemicals Has associated genes Has associated exposure references Shwartzman Phenomenon Has associated chemicals Has associated genes
2. DiseasesCardiovascular Diseases Has associated chemicals Has associated genes Has associated exposure references Vascular Diseases Has associated chemicals Has associated genes Has associated exposure references Vasculitis Has associated chemicals Has associated genes Has associated exposure references Shwartzman Phenomenon Has associated chemicals Has associated genes
3. DiseasesHemic and Lymphatic Diseases Has associated chemicals Has associated genes Has associated exposure references Hematologic Diseases Has associated chemicals Has associated genes Has associated exposure references Hemorrhagic Disorders Has associated chemicals Has associated genes Has associated exposure references Hemostatic Disorders Has associated chemicals Has associated genes Has associated exposure references Shwartzman Phenomenon Has associated chemicals Has associated genes

Top ↑ Descendants

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