Skip navigation

Disease Subacute Sclerosing Panencephalitis

Name Subacute Sclerosing Panencephalitis
Synonyms Encephaltis, Inclusion Body, Measles | Inclusion Body Encephalitis, Measles | Leukoencephalitides, Subacute Sclerosing | Leukoencephalitis, Subacute Sclerosing | Leukoencephalitis, Van Bogaert | Leukoencephalitis, Van Bogaerts | Leukoencephalitis, Van Bogaert's | Measles Inclusion Body Encephalitis | Panencephalitides, Subacute Sclerosing | Panencephalitis, Subacute Sclerosing | Sclerosing Leukoencephalitides, Subacute | Sclerosing Leukoencephalitis, Subacute | Sclerosing Panencephalitides, Subacute | Sclerosing Panencephalitis, Subacute | SSPE | Subacute Sclerosing Leukoencephalitides | Subacute Sclerosing Leukoencephalitis | Subacute Sclerosing Panencephalitides | Van Bogaert Leukoencephalitis | Van Bogaert's Leukoencephalitis | Van Bogaerts Leukoencephalitis
Definition A rare, slowly progressive encephalitis caused by chronic infection with the MEASLES VIRUS. The condition occurs primarily in children and young adults, approximately 2-8 years after the initial infection. A gradual decline in intellectual abilities and behavioral alterations are followed by progressive MYOCLONUS; MUSCLE SPASTICITY; SEIZURES; DEMENTIA; autonomic dysfunction; and ATAXIA. DEATH usually occurs 1-3 years after disease onset. Pathologic features include perivascular cuffing, eosinophilic cytoplasmic inclusions, neurophagia, and fibrous gliosis. It is caused by the SSPE virus, which is a defective variant of MEASLES VIRUS. (From Adams et al., Principles of Neurology, 6th ed, pp767-8)
Categories Nervous system disease | Viral disease
MeSH® ID D013344
External Links

Top ↑ Ancestors

1. DiseasesVirus Diseases Has associated chemicals Has associated genes Has associated exposure references Central Nervous System Viral Diseases Has associated chemicals Has associated genes Encephalitis, Viral Has associated chemicals Has associated genes Subacute Sclerosing Panencephalitis Has associated chemicals Has associated genes
2. DiseasesVirus Diseases Has associated chemicals Has associated genes Has associated exposure references Encephalitis, Viral Has associated chemicals Has associated genes Subacute Sclerosing Panencephalitis Has associated chemicals Has associated genes
3. DiseasesVirus Diseases Has associated chemicals Has associated genes Has associated exposure references RNA Virus Infections Has associated chemicals Has associated genes Has associated exposure references Mononegavirales Infections Has associated chemicals Has associated genes Paramyxoviridae Infections Has associated chemicals Has associated genes Morbillivirus Infections Has associated chemicals Has associated genes Measles Has associated chemicals Has associated genes Subacute Sclerosing Panencephalitis Has associated chemicals Has associated genes
4. DiseasesVirus Diseases Has associated chemicals Has associated genes Has associated exposure references Slow Virus Diseases Has associated chemicals Has associated genes Subacute Sclerosing Panencephalitis Has associated chemicals Has associated genes
5. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Central Nervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Brain Diseases Has associated chemicals Has associated genes Has associated exposure references Encephalitis Has associated chemicals Has associated genes Infectious Encephalitis Has associated chemicals Has associated genes Encephalitis, Viral Has associated chemicals Has associated genes Subacute Sclerosing Panencephalitis Has associated chemicals Has associated genes
6. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Central Nervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Central Nervous System Infections Has associated chemicals Has associated genes Central Nervous System Viral Diseases Has associated chemicals Has associated genes Encephalitis, Viral Has associated chemicals Has associated genes Subacute Sclerosing Panencephalitis Has associated chemicals Has associated genes
7. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Central Nervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Central Nervous System Infections Has associated chemicals Has associated genes Infectious Encephalitis Has associated chemicals Has associated genes Encephalitis, Viral Has associated chemicals Has associated genes Subacute Sclerosing Panencephalitis Has associated chemicals Has associated genes

Top ↑ Descendants

Subacute Sclerosing Panencephalitis Has associated chemicals Has associated genes
  Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy Has associated chemicals Has associated genes