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Disease Supranuclear Palsy, Progressive

Name Supranuclear Palsy, Progressive
Synonyms Ophthalmoplegia, Progressive Supranuclear | Palsy, Progressive Supranuclear | Progressive Supranuclear Ophthalmoplegia | Progressive Supranuclear Palsies | Progressive Supranuclear Palsy | PSNP1 | PSP | Richardson's Syndrome | Richardson Syndrome | Steele Richardson Olszewski Disease | Steele-Richardson-Olszewski Disease | Steele Richardson Olszewski Syndrome | Steele-Richardson-Olszewski Syndrome | Supranuclear Ophthalmoplegia, Progressive | Supranuclear Palsies, Progressive | Supranuclear Palsy, Progressive, 1 | Syndrome, Richardson's | Syndrome, Steele-Richardson-Olszewski
Definition A degenerative disease of the central nervous system characterized by balance difficulties; OCULAR MOTILITY DISORDERS (supranuclear ophthalmoplegia); DYSARTHRIA; swallowing difficulties; and axial DYSTONIA. Onset is usually in the fifth decade and disease progression occurs over several years. Pathologic findings include neurofibrillary degeneration and neuronal loss in the dorsal MESENCEPHALON; SUBTHALAMIC NUCLEUS; RED NUCLEUS; pallidum; dentate nucleus; and vestibular nuclei. (From Adams et al., Principles of Neurology, 6th ed, pp1076-7)
Categories Eye disease | Nervous system disease | Signs and symptoms
MeSH® ID D013494
OMIM® ID 601104
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Top ↑ Ancestors

1. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Central Nervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Brain Diseases Has associated chemicals Has associated genes Has associated exposure references Basal Ganglia Diseases Has associated chemicals Has associated genes Has associated exposure references Supranuclear Palsy, Progressive Has associated chemicals Has associated genes
2. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Central Nervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Movement Disorders Has associated chemicals Has associated genes Has associated exposure references Supranuclear Palsy, Progressive Has associated chemicals Has associated genes
3. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Cranial Nerve Diseases Has associated chemicals Has associated genes Has associated exposure references Ocular Motility Disorders Has associated chemicals Has associated genes Ophthalmoplegia Has associated chemicals Has associated genes Supranuclear Palsy, Progressive Has associated chemicals Has associated genes
4. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Neurodegenerative Diseases Has associated chemicals Has associated genes Has associated exposure references Tauopathies Has associated chemicals Has associated genes Has associated exposure references Supranuclear Palsy, Progressive Has associated chemicals Has associated genes
5. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Neurologic Manifestations Has associated chemicals Has associated genes Has associated exposure references Paralysis Has associated chemicals Has associated genes Ophthalmoplegia Has associated chemicals Has associated genes Supranuclear Palsy, Progressive Has associated chemicals Has associated genes
6. DiseasesEye Diseases Has associated chemicals Has associated genes Has associated exposure references Ocular Motility Disorders Has associated chemicals Has associated genes Ophthalmoplegia Has associated chemicals Has associated genes Supranuclear Palsy, Progressive Has associated chemicals Has associated genes
7. DiseasesPathological Conditions, Signs and Symptoms Has associated chemicals Has associated genes Has associated exposure references Signs and Symptoms Has associated chemicals Has associated genes Has associated exposure references Neurologic Manifestations Has associated chemicals Has associated genes Has associated exposure references Paralysis Has associated chemicals Has associated genes Ophthalmoplegia Has associated chemicals Has associated genes Supranuclear Palsy, Progressive Has associated chemicals Has associated genes

Top ↑ Descendants

Supranuclear Palsy, Progressive Has associated chemicals Has associated genes
  Familial progressive supranuclear palsy
  Progressive supranuclear palsy atypical Has associated chemicals Has associated genes
  Supranuclear Palsy, Progressive, 2
  Supranuclear Palsy, Progressive, 3
  Tauopathy and Respiratory Failure