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Disease Vascular Diseases

These are exposure studies associated with the disease and all of its children.

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1–50 of 87 results.
  Reference Associated Study Title Author's Summary Study Factors Stressor Receptors Country Medium Exposure Marker Measurements Outcome
1. Hansen AB, et al. (2016). Danish Nurse Cohort We examined the association between long-term exposure to particulate matter (PM2.5) and diabetes incidence; non-smokers, obese subjects, and cardiovascular disease patients may be most susceptible to development of diabetes related to air pollution. disease | tobacco Air Pollutants Subjects with disease:Diabetes Mellitus | Subjects with disease:Myocardial Infarction | Subjects with disease:Obesity | Study subjects Denmark air, ambient Nitrogen Dioxide | Nitrogen Oxides | Particulate Matter Details Diabetes Mellitus
2. Zhang P, et al. (2011). Long-term exposure to ambient air pollution is associated with the death of cardiovascular and cerebrovascular diseases among Chinese populations. The effects of air pollution were more evident in female that in male, and nonsmokers and residents with body mass index less than 18.5 were more vulnerable to outdoor air pollution. body mass index | sex | tobacco Air Pollutants Study subjects China air, ambient Nitrogen Dioxide | Particulate Matter | Sulfur Dioxide Details Cardiovascular Diseases | Cerebrovascular Disorders | Death
3. Künzli N, et al. (2010). B-Vitamin Atherosclerosis Intervention Trial (BVAIT) | Estrogen in the Prevention of Atherosclerosis Trial (EPAT) | Troglitazone Atherosclerosis Regression Trial (TART) | Vitamin E Atherosclerosis Prevention Study (VEAPS) | Women's Estrogen-Progestin Lipid-Lowering Hormone Atherosclerosis Regression Trial (WELL-HART) Consistent with cross-sectional findings and animal studies, this is the first study to report an association between exposure to air pollution and the progression of atherosclerosis - indicated with carotid artery intima-media thickness change - in humans. Air Pollutants Study subjects United States air Particulate Matter Details Atherosclerosis
4. Andersen ZJ, et al. (2012). Danish Diet, Cancer, and Health cohort Study Long-term exposure to traffic-related air pollution may contribute to the development of ischemic but not hemorrhagic stroke, especially severe ischemic strokes leading to death within 30 days. Air Pollutants Study subjects Denmark Nitrogen Dioxide Details Brain Ischemia | Cerebral Hemorrhage | Stroke
5. Pun VC, et al. (2015). Nurses' Health Study (NHS) Particulate matter in the prior 1 and 12 months is associated with pulmonary embolism risk, and women with underlying health conditions may be more susceptible to pulmonary embolism after particulate matter exposure. sex Air Pollutants Study subjects United States air, ambient Particulate Matter Details Pulmonary Embolism
6. Jones MR, et al. (2015). Multi-Ethnic Study of Atherosclerosis (MESA) The smaller carotid intima-media thickness levels in U.S. Chinese participants were even smaller after accounting for higher particulate matter (PM2.5) concentrations compared with Caucasian-Americans; however, air pollution was not related to intima-media thickness differences in African-Americans and Hispanics compared with Caucasian-Americans. race Air Pollutants Study subjects United States air, ambient Nitrogen Oxides | Particulate Matter Details Carotid Intimal Medial Thickness 1 | blood vessel development
7. Jung CR, et al. (2017). Our results provide new evidence that exposure to ozone may increase the risk of Kawasaki disease in children. Air Pollutants Children | Subjects with disease:Mucocutaneous Lymph Node Syndrome Taiwan, Province of China air, ambient Carbon Monoxide | Nitrogen Dioxide | Ozone | Particulate Matter | Sulfur Dioxide Details Mucocutaneous Lymph Node Syndrome
8. Brüske I, et al. (2011). Air Pollution and Inflammatory Response in Myocardial Infarction Survivors: Gene-Environment Interaction in a High Risk Group (AIRGENE) These preliminary findings should be replicated in other study populations because they suggest that the accumulation of acute and subacute effects or the chronic exposure to ambient particulate and gaseous air pollution may result in the promotion of atherosclerosis, mediated, at least in part, by increased levels of lipoprotein-associated phospholipase A2. Air Pollutants | Carbon Monoxide | Nitric Oxide | Nitrogen Dioxide | Ozone | Particulate Matter | Sulfur Dioxide Subjects with disease:Myocardial Infarction Germany air, ambient | plasma Carbon Monoxide | Nitric Oxide | Nitrogen Dioxide | Ozone | Particulate Matter | PLA2G7 | Sulfur Dioxide Details Atherosclerosis
9. Ljungman P, et al. (2009). Air Pollution and Inflammatory Response in Myocardial Infarction Survivors: Gene-Environment Interaction in a High Risk Group (AIRGENE) We found the interleukin-6 response to air pollution is modified by genetic polymorphisms in IL6 and FGB genes, suggesting the effect of gaseous traffic-related air pollution on inflammation may be stronger in genetic subpopulations with ischemic heart disease. disease | genetics Air Pollutants | Carbon Monoxide | Vehicle Emissions Subjects with gene influence:FGB | Subjects with gene influence:IL6 | Subjects with disease:Myocardial Infarction Finland|Germany|
Greece|Italy|
Spain|Sweden
air, ambient | plasma Carbon Monoxide | IL6 | Nitrogen Dioxide | Particulate Matter Details positive regulation of interleukin-6 production
10. Delfino RJ, et al. (2010). Traffic emission sources of organic chemicals represented by polycyclic aromatic hydrocarbons are associated with increased systemic inflammation and explain associations with quasi-ultrafine particle mass. Air Pollutants | hopane | Polycyclic Aromatic Hydrocarbons | Vehicle Emissions Subjects with disease:Coronary Artery Disease United States air, outdoor | plasma Alkanes | Chromium | Copper | hopane | IL6 | Iron | Manganese | Nickel | Particulate Matter | Polycyclic Aromatic Hydrocarbons | TNFRSF1B | Vanadium | Zinc Details
11. Levinsson A, et al. (2014). INTERGENE/ADONIX Air pollution exposure entails an increased risk of acute myocardial infarction, and this risk differed over genotype strata for variants in the GSTP1, GSTT1 and GSTCD genes, albeit not statistically-significantly. genetics Air Pollutants | Nitrogen Dioxide Subjects with gene influence:GSTP1 | Controls for disease:Myocardial Infarction | Subjects with disease:Myocardial Infarction Sweden Nitrogen Dioxide Details Hypertension | Myocardial Infarction
12. Hankey S, et al. (2012). Between-neighborhood differences in estimated ischemic heart disease mortality from air pollution were comparable in magnitude, suggesting that population health benefits from increased physical activity in high-walkability neighborhoods may be offset by adverse effects of air pollution exposure. physical activity Air Pollutants | Nitrogen Oxides | Ozone | Particulate Matter Study subjects United States air Nitrogen Dioxide | Nitrogen Oxides | Ozone | Particulate Matter Details Myocardial Ischemia
13. Ward-Caviness CK, et al. (2016). CATHeterization GENetics (CATHGEN) Our results reveal a novel gene (and possibly gene family) associated with peripheral arterial disease, via an interaction with traffic air pollution exposure; these results highlight the potential for interactions studies, particularly at the genome scale, to reveal novel biology linking environmental exposures to clinical outcomes. genetics Air Pollutants | Vehicle Emissions Subjects with gene influence:BMP2 | Subjects with gene influence:BMP8A United States Details Peripheral Arterial Disease
14. Lee WJ, et al. (2004). Agricultural Health Study (AHS) Our findings suggest a possible association between alachlor application and incidence of lymphohematopoietic cancers among applicators in the Agricultural Health Study. alachlor Workers United States Details Agricultural Workers' Diseases | Hematologic Neoplasms | Leukemia | Multiple Myeloma
15. Stamp LK, et al. (2015). We have replicated findings identifying dust exposure (grain and silica) and farm exposure as risk factors for granulomatosis with polyangiitis; we have shown activities associated with exposure to inhaled antigens (in particular those related to farming or gardening) may increase the risk of the disease. Antigens | Dust | Silicon Dioxide Controls for disease:Granulomatosis with Polyangiitis | Subjects with disease:Granulomatosis with Polyangiitis New Zealand Details Granulomatosis with Polyangiitis
16. Pi J, et al. (2005). A 13-month arsenic exposure reduction effectively reverses the arsenic-induced impairment of the nitric oxide/cyclic guanosine 3',5'-monophosphate pathway in both males and females and improves peripheral vascular function in males. Arsenic Study subjects China blood | urine | water Arsenic | Cyclic GMP Details Arsenic Poisoning | Vascular Diseases
17. Zierold KM, et al. (2004). Respondents with arsenic levels of 2 microg/L or greater were statistically more likely to report a history of depression, high blood pressure, circulatory problems, and bypass surgery than were respondents with arsenic concentrations less than 2 microg/L. Arsenic Study subjects United States water Arsenic Details Depressive Disorder | Heart Diseases | Hypertension
18. Yuan Y, et al. (2007). We conclude that the major impact of arsenic in drinking water on circulatory disease involves acute myocardial infarction and that, in the initial years, it is the main cause of death from arsenic in drinking water, superseded in later years by excess mortality from lung and bladder cancer. Arsenic Study subjects Chile water Arsenic Details Lung Neoplasms | Myocardial Infarction | Urinary Bladder Neoplasms
19. Osorio-Yáñez C, et al. (2013). Arsenic exposure was positively associated with carotid intima-media thickness in a population of Mexican children with environmental arsenic exposure through drinking water. diet Arsenic Children Mexico plasma | urine | water, drinking Arsenicals | Arsenic | Cacodylic Acid | ICAM1 | monomethylarsonic acid | VCAM1 Details Carotid Intimal Medial Thickness 1 | blood vessel development
20. Wade TJ, et al. (2009). This is the first study to document increased arsenic-associated mortality in the Bayingnormen Inner Mongolia region of China. Arsenic Study subjects China water Arsenic Details Coronary Disease | Death | Neoplasms
21. Jones MR, et al. (2011). National Health and Nutrition Examination Survey (NHANES) At the low to moderate levels typical of the U.S. population, total arsenic, total arsenic minus arsenobetaine, and dimethylarsinate concentrations in urine were not associated with the prevalence of hypertension or with systolic or diastolic blood pressure levels. A weak association of dimethylarsinate with hypertension could not be ruled out. Arsenic | arsenobetaine | Cacodylic Acid Controls for disease:Hypertension | Subjects with disease:Hypertension | Study subjects United States urine Arsenic | arsenobetaine | Cacodylic Acid Details
22. Ghazali AR, et al. (2012). There were significant correlations between heavy metals with subject's age and working period as farmers. age Arsenic | Cadmium | Lead Controls for disease:Hypertension | Subjects with disease:Hypertension | Workers Malaysia nail Arsenic | Cadmium | Lead Details
23. Thurston GD, et al. (2016). American Cancer Society Cancer Prevention Study II (ACS CPS-II) Long-term fine particulate matter (PM2.5) exposures from fossil fuel combustion, especially coal burning but also from diesel traffic, were associated with increases in ischemic heart disease mortality in this nationwide population. Arsenic | Carbon | Chlorine | Iron | Lead | Manganese | Particulate Matter | Potassium | Selenium | Silicon | Soot | Sulfur Study subjects United States air, ambient | soil Arsenic | Calcium | Carbon | Chlorine | Iron | Lead | Manganese | Nickel | Particulate Matter | Potassium | Selenium | Silicon | Sodium | Soot | Sulfur | Vanadium | Zinc Details Death | Myocardial Ischemia
24. Melzer D, et al. (2010). National Health and Nutrition Examination Survey (NHANES) Higher Bisphenol A (BPA) exposure, reflected in higher urinary concentrations of BPA, is consistently associated with reported heart disease in the general adult population of the USA. bisphenol A Study subjects United States urine bisphenol A Details Angina Pectoris | Coronary Disease | Diabetes Mellitus | Myocardial Infarction | alkaline phosphatase activity | lactate dehydrogenase activity
25. Shankar A, et al. (2012). National Health and Nutrition Examination Survey (NHANES) Urinary bisphenol A levels were significantly associated with peripheral arterial disease, independent of traditional cardiovascular disease risk factors. race | sex | tobacco bisphenol A Study subjects United States urine bisphenol A Details Peripheral Arterial Disease
26. Shankar A, et al. (2012). National Health and Nutrition Examination Survey (NHANES) We observed a positive association between increasing levels of urinary bisphenol A and hypertension independent of confounding factors such as age, gender, race/ethnicity, smoking, body mass index, diabetes mellitus and total serum cholesterol levels. bisphenol A Study subjects United States urine bisphenol A Details Hypertension
27. Melzer D, et al. (2012). European Prospective Investigation into Cancer and Nutrition (EPIC) Study Associations between higher bisphenol A exposure (reflected in higher urinary concentrations) and incident coronary artery disease during >10 years of follow-up showed trends similar to previously reported cross-sectional findings in the more highly exposed NHANES respondents. bisphenol A Controls for disease:Coronary Artery Disease | Subjects with disease:Coronary Artery Disease United Kingdom urine bisphenol A Details Coronary Artery Disease
28. Satarug S, et al. (2017). National Health and Nutrition Examination Survey (NHANES) Using a Cadmium-toxicokinetic simulation model, we have found that current tolerable dietary intake guidelines do not contain a safety margin, given that the modeled dietary intake levels exceed the levels associated with kidney damage and many other adverse health outcomes seen in cohorts and cross-sectional studies. Cadmium Controls for disease:Breast Neoplasms | Subjects with disease:Breast Neoplasms | Study subjects Japan|United States urine Details Breast Neoplasms | Kidney Diseases | Vascular Diseases
29. Barregard L, et al. (2016). Malmo Diet and Cancer Study Blood cadmium in the highest quartile was associated with incident cardiovascular disease and mortality in our population-based samples of Swedish adults. tobacco Cadmium Study subjects Sweden blood Cadmium Details Cardiovascular Diseases | Myocardial Ischemia | Stroke
30. Peters JL, et al. (2010). National Health and Nutrition Examination Survey (NHANES) Environmental exposure to cadmium was associated with significantly increased stroke and heart failure prevalence. sex | tobacco Cadmium Study subjects United States blood | urine Cadmium Details Heart Failure | Stroke
31. Min JY, et al. (2016). National Health and Nutrition Examination Survey (NHANES) We observed a significant association between blood cadmium levels and Alzheimer disease mortality among older adults in the US. age Cadmium Controls for disease:Diabetes Mellitus | Subjects with disease:Diabetes Mellitus | Controls for disease:Hypertension | Subjects with disease:Hypertension | Study subjects United States blood Cadmium Details Alzheimer Disease
32. Tellez-Plaza M, et al. (2010). National Health and Nutrition Examination Survey (NHANES) In this representative sample of the US population, high cadmium levels were associated with an increased prevalence of Peripheral Artery Disease (PAD), but the association between cadmium and PAD at low cadmium exposures was markedly different in men and women. sex Cadmium | Cotinine | Lead Controls for disease:Peripheral Arterial Disease | Subjects with disease:Peripheral Arterial Disease | Study subjects United States blood | serum | urine Cadmium | Cotinine | Lead Details Peripheral Arterial Disease
33. Ferrandiz J, et al. (2004). We used exposure analysis to assess the effect of both protective factors-calcium and magnesium-on mortality from cerebrovascular (ICD-9 430-438) and ischemic heart (ICD-9 410-414) diseases. This study provides statistical evidence of the relationship between mortality from cardiovascular diseases and hardness of drinking water. Calcium | Magnesium Study subjects Spain Details Cardiovascular Diseases | Cerebrovascular Disorders | Death
34. Dayton SB, et al. (2010). Agricultural Health Study (AHS) We investigated the relationship between agricultural pesticide use and the incidence of myocardial infarction among women in the Agricultural Health Study. Carbofuran | Chlorpyrifos | Coumaphos | metalaxyl | pendimethalin | Trifluralin Study subjects | Workers United States Details Agricultural Workers' Diseases | Myocardial Infarction
35. Suh HH, et al. (2010). Results indicate decreased vagal tone in response to traffic pollutants, which can best be detected with precise personal exposure measures. Carbon | Nitrogen Dioxide | Ozone | Particulate Matter | Sulfates Subjects with disease:Myocardial Infarction | Subjects with disease:Pulmonary Disease, Chronic Obstructive | Study subjects United States air Carbon | Nitrogen Dioxide | Ozone | Particulate Matter | Sulfates Details heart contraction
36. Baccarelli A, et al. (2011). Beijing Truck Driver Air Pollution Study (BTDAS) Our results indicate delayed effects of ambient Particulate Matter (PM10) on blood pressure. Carbon | Particulate Matter Workers China air, ambient | air, personal Carbon | Particulate Matter Details Hypertension
37. Ghosh R, et al. (2016). We investigated the coronary heart disease burden from near-roadway air pollution and compared it with the particulate matter <= 2.5 microns burden in the California South Coast Air Basin for 2008 and under a compact urban growth greenhouse gas reduction scenario for 2035. Carbon | Particulate Matter Study subjects United States Carbon | Particulate Matter Details Coronary Disease | Death
38. Berglind N, et al. (2010). Swedish Onset study This study provides no support that moderately elevated air pollution levels trigger first-time myocardial infarction. Carbon Monoxide | Nitrogen Dioxide | Ozone | Particulate Matter Subjects with disease:Myocardial Infarction Sweden air Carbon Monoxide | Nitrogen Dioxide | Ozone | Particulate Matter Details Myocardial Infarction
39. Koken PJ, et al. (2003). In summary, the results of this study in Denver suggest that ozone increases the risk of hospitalization for acute myocardial infarction, coronary atherosclerosis, and pulmonary heart disease. Sulfur dioxide appears to be related to increased hospital stays for cardiac dysrhythmias, and carbon monoxide is significantly associated with congestive heart failure hospitalization. sex Carbon Monoxide | Nitrogen Dioxide | Ozone | Particulate Matter | Sulfur Dioxide Study subjects United States air Carbon Monoxide | Nitrogen Dioxide | Ozone | Sulfur Dioxide Details Arrhythmias, Cardiac | Atherosclerosis | Heart Failure | Myocardial Infarction | Pulmonary Heart Disease
40. Milojevic A, et al. (2014). This study found no clear evidence for pollution effects on ST-elevation myocardial infarctions and stroke, which ultimately represent thrombogenic processes, though it did for pulmonary embolism. age | sex Carbon Monoxide | Nitrogen Dioxide | Ozone | Particulate Matter | Sulfur Dioxide Study subjects United Kingdom air, ambient Carbon Monoxide | Nitrogen Dioxide | Ozone | Particulate Matter | Sulfur Dioxide Details Arrhythmias, Cardiac | Atrial Fibrillation | Cardiovascular Diseases | Death | Stroke
41. Wylie BJ, et al. (2017). Prenatal Iron Supplements Study Our results suggest that prenatal exposure to inhaled particulate matter and carbon monoxide may be associated with fetal thrombosis in a dose-dependent matter. Carbon Monoxide | Particulate Matter Fetuses | Pregnant females Tanzania, United Republic of air Carbon Monoxide | Particulate Matter Details Chorioamnionitis | Thrombosis | inflammatory response
42. Kim C, et al. (2016). Shanghai Women's Health Study (SWHS) Evidence from this study suggests that past use of coal among women in Shanghai is associated with excess all-cause mortality and from cardiovascular diseases in particular. Coal Study subjects China Details Cardiovascular Diseases | Death | Myocardial Infarction | Neoplasms
43. Alavanja MC, et al. (2014). Agricultural Health Study (AHS) Our results show pesticides from different chemical and functional classes were associated with an excess risk of non-Hodgkin lymphoma and subtypes, but not all members of any single class of pesticides were associated with an elevated risk; these findings are among the first to suggest links between DDT, lindane, permethrin, diazinon and terbufos with non-Hodgkin lymphoma subtypes. DDT | Diazinon | Lindane | Permethrin | terbufos Workers United States Details Lymphoma, Follicular | Lymphoma, Non-Hodgkin | Multiple Myeloma
44. Shcherbatykh I, et al. (2005). These results suggest that living near a source of persistent organic pollutants contamination constitutes a risk of exposure and an increased risk of acquiring cerebrovascular disease. age | race | sex Dioxins | Pesticides | Polychlorinated Biphenyls Study subjects United States Details Cerebral Infarction
45. Amin R, et al. (2017). We find that gadolinium use during pregnancy is unlikely to be associated with adverse effects in infants during the neonatal period. Gadolinium Infants or newborns | Pregnant females United States blood, cord Gadolinium Details Birth Weight | Bone Diseases, Metabolic | Chorioamnionitis | Diabetes, Gestational | Ductus Arteriosus, Patent | Enterocolitis, Necrotizing | Fetal Growth Retardation | Hyperbilirubinemia, Neonatal | Hypertension, Pregnancy-Induced | Lung Diseases | Obstetric Labor, Premature | Oligohydramnios | Prenatal Exposure Delayed Effects | Respiratory Distress Syndrome, Newborn | Retinopathy of Prematurity
46. Sorahan T. (2015). Agricultural Health Study (AHS) There were no statistically significant trends for multiple myeloma risks in relation to reported cumulative days (or intensity weighted days) of glyphosate use; the doubling of risk reported previously arose from the use of an unrepresentative restricted dataset, and analyses of the full dataset provides no convincing evidence for a link between multiple myeloma risk and glyphosate use. glyphosate Workers United States Details Multiple Myeloma
47. De Roos AJ, et al. (2005). Agricultural Health Study (AHS) Glyphosate exposure was not associated with cancer incidence overall or with most of the cancer subtypes we studied. There was a suggested association with multiple myeloma incidence that should be followed up as more cases occur in the Agricultural Health Study. glyphosate Workers United States Details Multiple Myeloma
48. Gensburg LJ, et al. (2009). The aim of this study was to describe the mortality experience of the former Love Canal residents from the years 1979-1996. Hazardous Waste Study subjects United States Details Myocardial Infarction
49. Scinicariello F, et al. (2010). National Health and Nutrition Examination Survey (NHANES) Blood lead levels may be an important risk factor for hypertension and increased systolic and diastolic blood pressure, and these associations may be modified by ALAD genotype. genetics | race Lead Subjects with gene influence:ALAD | Study subjects United States blood Lead Details Hypertension | regulation of blood pressure
50. Peters JL, et al. (2007). Normative Aging Study (NAS) Our findings indicate that in this population of older men, bone lead is more likely to be associated with elevated systolic blood pressure and with increased risk of developing hypertension among men with higher levels of self-reported stress than among those reporting lower stress levels. Lead Controls for disease:Hypertension | Subjects with disease:Hypertension | Veterans United States blood | bone | patella | tibia Lead Details Hypertension
1–50 of 87 results.