Skip navigation

Disease Spinal Muscular Atrophies of Childhood

Name Spinal Muscular Atrophies of Childhood
Synonyms Atrophies, Infantile Muscular | Atrophies, Juvenile Muscular | Atrophy, Infantile Muscular | Atrophy, Juvenile Muscular | HMN (Hereditary Motor Neuropathy) Proximal Type I | Hoffman Diseases, Werdnig | Hoffman Disease, Werdnig | Infantile Muscular Atrophies | Infantile Muscular Atrophy | Infantile Spinal Muscular Atrophy | Juvenile Muscular Atrophies | Juvenile Muscular Atrophy | Juvenile Spinal Muscular Atrophy | Kugelberg Welander Disease | Kugelberg-Welander Disease | Kugelberg Welander Syndrome | Kugelberg-Welander Syndrome | KUGELBERG-WELANDER SYNDROME, AUTOSOMAL DOMINANT | Kugelberg-Welander Syndromes | KWS | Muscular Atrophies, Juvenile | Muscular Atrophy, Infantile | Muscular Atrophy, Juvenile | Muscular Atrophy, Spinal, Infantile | MUSCULAR ATROPHY, SPINAL, INFANTILE CHRONIC FORM | MUSCULAR ATROPHY, SPINAL, INTERMEDIATE TYPE | Muscular Atrophy, Spinal, Type I | Muscular Atrophy, Spinal, Type II | Muscular Atrophy, Spinal, Type III | Proximal Hereditary Motor Neuropathy Type I | SMA1 | SMA2 | SMA3 | SMA I | SMA II | SMA III | SMA, Infantile Acute Form | SMA-LED | SMALED1 | Spinal Muscular Atrophy 1 | SPINAL MUSCULAR ATROPHY, CHILDHOOD, PROXIMAL, AUTOSOMAL DOMINANT | Spinal Muscular Atrophy, Infantile | Spinal Muscular Atrophy, Juvenile | SPINAL MUSCULAR ATROPHY, JUVENILE, PROXIMAL, AUTOSOMAL DOMINANT | SPINAL MUSCULAR ATROPHY, LOWER EXTREMITY-PREDOMINANT, 1, AUTOSOMAL DOMINANT | Spinal Muscular Atrophy, Mild Childhood and Adolescent Form | Spinal Muscular Atrophy Type 2 | Spinal Muscular Atrophy, Type 3 | Spinal Muscular Atrophy Type I | Spinal Muscular Atrophy, Type I | Spinal Muscular Atrophy Type II | Spinal Muscular Atrophy, Type II | Spinal Muscular Atrophy Type III | Spinal Muscular Atrophy, Type III | Type III Spinal Muscular Atrophy | Type II Spinal Muscular Atrophy | Type I Spinal Muscular Atrophy | Werdnig Hoffman Disease | Werdnig Hoffman Diseases | Werdnig Hoffmann Disease | Werdnig-Hoffmann Disease
Definition A group of recessively inherited diseases that feature progressive muscular atrophy and hypotonia. They are classified as type I (Werdnig-Hoffman disease), type II (intermediate form), and type III (Kugelberg-Welander disease). Type I is fatal in infancy, type II has a late infantile onset and is associated with survival into the second or third decade. Type III has its onset in childhood, and is slowly progressive. (J Med Genet 1996 Apr:33(4):281-3)
Categories Genetic disease (inborn) | Nervous system disease
MeSH® ID D014897
OMIM® IDs 158600 | 253300 | 253400 | 253550
External Links

Top ↑ Ancestors

1. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Central Nervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Spinal Cord Diseases Has associated chemicals Has associated genes Has associated exposure references Muscular Atrophy, Spinal Has associated chemicals Has associated genes Has associated exposure references Spinal Muscular Atrophies of Childhood Has associated chemicals Has associated genes
2. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Neurodegenerative Diseases Has associated chemicals Has associated genes Has associated exposure references Heredodegenerative Disorders, Nervous System Has associated chemicals Has associated genes Spinal Muscular Atrophies of Childhood Has associated chemicals Has associated genes
3. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Neurodegenerative Diseases Has associated chemicals Has associated genes Has associated exposure references Motor Neuron Disease Has associated chemicals Has associated genes Has associated exposure references Muscular Atrophy, Spinal Has associated chemicals Has associated genes Has associated exposure references Spinal Muscular Atrophies of Childhood Has associated chemicals Has associated genes
4. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Neuromuscular Diseases Has associated chemicals Has associated genes Has associated exposure references Motor Neuron Disease Has associated chemicals Has associated genes Has associated exposure references Muscular Atrophy, Spinal Has associated chemicals Has associated genes Has associated exposure references Spinal Muscular Atrophies of Childhood Has associated chemicals Has associated genes
5. DiseasesCongenital, Hereditary, and Neonatal Diseases and Abnormalities Has associated chemicals Has associated genes Has associated exposure references Genetic Diseases, Inborn Has associated chemicals Has associated genes Has associated exposure references Heredodegenerative Disorders, Nervous System Has associated chemicals Has associated genes Spinal Muscular Atrophies of Childhood Has associated chemicals Has associated genes

Top ↑ Descendants

Spinal Muscular Atrophies of Childhood Has associated chemicals Has associated genes
  Amyotrophy, monomelic
  Hamano Tsukamoto syndrome
  Muscular atrophy, spinal, infantile chronic form
  Spinal Muscular Atrophy, Childhood, Proximal, Autosomal Dominant
  Spinal Muscular Atrophy, Distal, Autosomal Recessive, 4 Has associated chemicals Has associated genes
  Spinal Muscular Atrophy, Type I, with Congenital Bone Fractures
  Spinal Muscular Atrophy with Microcephaly and Mental Subnormality