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Disease Wolman Disease

Name Wolman Disease
Synonyms Acid Cholesteryl Ester Hydrolase Deficiency, Wolman Type | Acid Lipase Deficiency | Disease, Wolman | Disease, Wolman's | Familial Xanthomatoses | Familial Xanthomatosis | Liposomal Acid Lipase Deficiency, Wolman Type | Wolman's Disease | Wolmans Disease | Wolman's Xanthomatosis | Xanthomatoses, Familial | Xanthomatosis, Familial | Xanthomatosis, Wolman | Xanthomatosis, Wolmans | Xanthomatosis, Wolman's
Definition The severe infantile form of inherited lysosomal lipid storage diseases due to deficiency of acid lipase (STEROL ESTERASE). It is characterized by the accumulation of neutral lipids, particularly CHOLESTEROL ESTERS in leukocytes, fibroblasts, and hepatocytes. It is also known as Wolman's xanthomatosis and is an allelic variant of CHOLESTEROL ESTER STORAGE DISEASE.
Categories Genetic disease (inborn) | Infant-newborn disease | Metabolic disease
MeSH® ID D015223
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Top ↑ Ancestors

1. DiseasesCongenital, Hereditary, and Neonatal Diseases and Abnormalities Has associated chemicals Has associated genes Has associated exposure references Genetic Diseases, Inborn Has associated chemicals Has associated genes Has associated exposure references Metabolism, Inborn Errors Has associated chemicals Has associated genes Has associated exposure references Lipid Metabolism, Inborn Errors Has associated chemicals Has associated genes Lipidoses Has associated chemicals Has associated genes Cholesterol Ester Storage Disease Has associated chemicals Has associated genes Wolman Disease Has associated chemicals Has associated genes
2. DiseasesCongenital, Hereditary, and Neonatal Diseases and Abnormalities Has associated chemicals Has associated genes Has associated exposure references Genetic Diseases, Inborn Has associated chemicals Has associated genes Has associated exposure references Metabolism, Inborn Errors Has associated chemicals Has associated genes Has associated exposure references Lysosomal Storage Diseases Has associated chemicals Has associated genes Cholesterol Ester Storage Disease Has associated chemicals Has associated genes Wolman Disease Has associated chemicals Has associated genes
3. DiseasesCongenital, Hereditary, and Neonatal Diseases and Abnormalities Has associated chemicals Has associated genes Has associated exposure references Infant, Newborn, Diseases Has associated chemicals Has associated genes Has associated exposure references Wolman Disease Has associated chemicals Has associated genes
4. DiseasesNutritional and Metabolic Diseases Has associated chemicals Has associated genes Has associated exposure references Metabolic Diseases Has associated chemicals Has associated genes Has associated exposure references Lipid Metabolism Disorders Has associated chemicals Has associated genes Has associated exposure references Lipidoses Has associated chemicals Has associated genes Cholesterol Ester Storage Disease Has associated chemicals Has associated genes Wolman Disease Has associated chemicals Has associated genes
5. DiseasesNutritional and Metabolic Diseases Has associated chemicals Has associated genes Has associated exposure references Metabolic Diseases Has associated chemicals Has associated genes Has associated exposure references Metabolism, Inborn Errors Has associated chemicals Has associated genes Has associated exposure references Lipid Metabolism, Inborn Errors Has associated chemicals Has associated genes Lipidoses Has associated chemicals Has associated genes Cholesterol Ester Storage Disease Has associated chemicals Has associated genes Wolman Disease Has associated chemicals Has associated genes
6. DiseasesNutritional and Metabolic Diseases Has associated chemicals Has associated genes Has associated exposure references Metabolic Diseases Has associated chemicals Has associated genes Has associated exposure references Metabolism, Inborn Errors Has associated chemicals Has associated genes Has associated exposure references Lysosomal Storage Diseases Has associated chemicals Has associated genes Cholesterol Ester Storage Disease Has associated chemicals Has associated genes Wolman Disease Has associated chemicals Has associated genes

Top ↑ Descendants

Wolman Disease Has associated chemicals Has associated genes
  Lysosomal acid lipase deficiency Has associated chemicals Has associated genes
  Wolman Disease with Hypolipoproteinemia and Acanthocytosis