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Disease Paraparesis, Tropical Spastic

Name Paraparesis, Tropical Spastic
Synonyms Familial Spastic Paraparesis, Htlv 1 Associated | Familial Spastic Paraparesis, Htlv-1-Associated | HAM | Htlv-1-Associated Myelopathies | Htlv-1-Associated Myelopathy | HTLV I Associated Myelopathies | HTLV-I-Associated Myelopathies | HTLV I Associated Myelopathy | HTLV-I-Associated Myelopathy | HTLV I Associated Myelopathy Tropical Spastic Paraparesis | HTLV-I-Associated Myelopathy-Tropical Spastic Paraparesis | Human T Lymphotropic Virus Type 1 Associated Myelopathy | Human T-Lymphotropic Virus Type 1 Associated Myelopathy | Myelopathies, Htlv-1-Associated | Myelopathies, HTLV I Associated | Myelopathies, HTLV-I-Associated | Myelopathy, Htlv 1 Associated | Myelopathy, Htlv-1-Associated | Myelopathy, HTLV-I-Associated | Myelopathy, Human T Lymphotropic Virus Type 1 Associated | Myelopathy, Human T-Lymphotropic Virus Type 1 Associated | Parapareses, Tropical Spastic | Paraplegias, Tropical Spastic | Paraplegia, Tropical Spastic | Spastic Parapareses, Tropical | Spastic Paraparesis, Tropical | Spastic Paraplegias, Tropical | Spastic Paraplegia, Tropical | Tropical Spastic Parapareses | Tropical Spastic Paraparesis | Tropical Spastic Paraplegia | Tropical Spastic Paraplegias
Definition A subacute paralytic myeloneuropathy occurring endemically in tropical areas such as the Caribbean, Colombia, India, and Africa, as well as in the southwestern region of Japan; associated with infection by HUMAN T-CELL LEUKEMIA VIRUS I. Clinical manifestations include a slowly progressive spastic weakness of the legs, increased reflexes, Babinski signs, incontinence, and loss of vibratory and position sensation. On pathologic examination inflammatory, demyelination, and necrotic lesions may be found in the spinal cord. (Adams et al., Principles of Neurology, 6th ed, p1239)
Categories Nervous system disease | Viral disease
MeSH® ID D015493
OMIM® ID 159580
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1. DiseasesVirus Diseases Has associated chemicals Has associated genes Has associated exposure references RNA Virus Infections Has associated chemicals Has associated genes Has associated exposure references Retroviridae Infections Has associated chemicals Has associated genes Deltaretrovirus Infections Has associated chemicals Has associated genes HTLV-I Infections Has associated chemicals Has associated genes Paraparesis, Tropical Spastic Has associated chemicals Has associated genes
2. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Central Nervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Central Nervous System Infections Has associated chemicals Has associated genes Myelitis Has associated chemicals Has associated genes Paraparesis, Tropical Spastic Has associated chemicals Has associated genes
3. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Central Nervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Spinal Cord Diseases Has associated chemicals Has associated genes Has associated exposure references Myelitis Has associated chemicals Has associated genes Paraparesis, Tropical Spastic Has associated chemicals Has associated genes

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