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Disease Eye Diseases, Hereditary

These phenotypes are associated with Eye Diseases, Hereditary or its descendants. A phenotype has an inferred association via a curated chemical interaction or a gene-GO annotation or both.

1–50 of 15,287 results.
  Phenotype Disease Chemical Inference Network Gene Inference Network References
1. apoptotic process Color Vision Defects Inferred via 18 chemicals: Amiodarone | Chloroquine | Ciprofloxacin | Clioquinol | Cocaine | Deferoxamine | Digoxin | Folic Acid | Ibuprofen | Methotrexate | Minoxidil | Phenytoin | Quinidine | Ranitidine | Ribavirin | Smoke | Tamoxifen | Valproic Acid   153
2. cell proliferation Color Vision Defects Inferred via 17 chemicals: Amiodarone | Chloroquine | Ciprofloxacin | Clioquinol | Cocaine | Deferoxamine | Folic Acid | Ibuprofen | Methotrexate | Minoxidil | Phenytoin | Quinidine | Ranitidine | Ribavirin | Smoke | Tamoxifen | Valproic Acid   132
3. cell death Color Vision Defects Inferred via 15 chemicals: Amiodarone | Carbamazepine | Chloroquine | Clioquinol | Cocaine | Deferoxamine | Digoxin | Ibuprofen | Methotrexate | Phenytoin | Quinidine | Ribavirin | Smoke | Tamoxifen | Valproic Acid   97
4. cell proliferation Retinal Degeneration Inferred via 14 chemicals: Deferoxamine | Edaravone | Fenretinide | Hydrocarbons, Chlorinated | Iron | mancozeb | Maneb | Methylnitrosourea | Ofloxacin | Paraquat | Rotenone | tauroursodeoxycholic acid | Vincristine | Zinc Inferred via 2 genes: BCL2 | GDNF 75
5. positive regulation of cell death Color Vision Defects Inferred via 14 chemicals: Amiodarone | Carbamazepine | Chloroquine | Clioquinol | Deferoxamine | Digoxin | Folic Acid | Ibuprofen | Methotrexate | Phenytoin | Smoke | Tamoxifen | Thioridazine | Valproic Acid   68
6. apoptotic process Retinal Degeneration Inferred via 13 chemicals: Deferoxamine | Edaravone | Fenretinide | Iron | Maneb | Methylnitrosourea | Niacin | Ofloxacin | Paraquat | Rotenone | tauroursodeoxycholic acid | Vincristine | Zinc Inferred via 1 gene: BCL2 138
7. cell death Retinal Degeneration Inferred via 12 chemicals: 9-cis-retinal | Deferoxamine | Fenretinide | Iron | mancozeb | Maneb | Ofloxacin | Paraquat | Rotenone | tauroursodeoxycholic acid | Vincristine | Zinc   111
8. positive regulation of cell death Retinal Degeneration Inferred via 12 chemicals: Deferoxamine | Fenretinide | Hydrocarbons, Chlorinated | mancozeb | Maneb | Niacin | Paraquat | Retinaldehyde | Rotenone | Thioridazine | Vincristine | Zinc   62
9. regulation of blood pressure Color Vision Defects Inferred via 11 chemicals: Chloroquine | Cocaine | Digoxin | Folic Acid | Ibuprofen | Linezolid | Minoxidil | Quinidine | Ranitidine | Smoke | Valproic Acid   87
10. regulation of mitochondrial membrane potential Retinal Degeneration Inferred via 10 chemicals: Deferoxamine | Edaravone | Fenretinide | Iron | Methylene Blue | Paraquat | Rotenone | tauroursodeoxycholic acid | Vincristine | Zinc Inferred via 2 genes: BCL2 | SOD1 43
11. positive regulation of apoptotic process Retinal Degeneration Inferred via 10 chemicals: Deferoxamine | Edaravone | mancozeb | Paraquat | Retinaldehyde | Rotenone | tauroursodeoxycholic acid | Vincristine | Zinc | Ziram Inferred via 1 gene: SOD1 39
12. positive regulation of reactive oxygen species biosynthetic process Retinal Degeneration Inferred via 9 chemicals: Deferoxamine | Edaravone | Fenretinide | Iron | mancozeb | Paraquat | Retinaldehyde | Rotenone | Zinc   43
13. cell cycle Color Vision Defects Inferred via 9 chemicals: Chloroquine | Ciprofloxacin | Cocaine | Deferoxamine | Ibuprofen | Methotrexate | Quinidine | Tamoxifen | Valproic Acid   36
14. lipid oxidation Retinal Degeneration Inferred via 9 chemicals: Edaravone | Iron | mancozeb | Maneb | Methylene Blue | Paraquat | Rotenone | Vincristine | Zinc   31
15. glutathione metabolic process Retinal Degeneration Inferred via 8 chemicals: Deferoxamine | Edaravone | Fenretinide | Maneb | Paraquat | Rotenone | Vincristine | Zinc Inferred via 1 gene: SOD1 28
16. positive regulation of apoptotic process Color Vision Defects Inferred via 8 chemicals: Amiodarone | Carbamazepine | Chloroquine | Deferoxamine | Ibuprofen | Methotrexate | Tamoxifen | Valproic Acid Inferred via 1 gene: ATF6 48
17. DNA damage response, detection of DNA damage Retinal Degeneration Inferred via 8 chemicals: Deferoxamine | mancozeb | Maneb | Methylene Blue | Methylnitrosourea | Paraquat | Rotenone | Zinc   25
18. reactive oxygen species biosynthetic process Color Vision Defects Inferred via 8 chemicals: Amiodarone | Chloroquine | Ciprofloxacin | Cocaine | Deferoxamine | Smoke | Tamoxifen | Valproic Acid   20
19. glutathione biosynthetic process Color Vision Defects Inferred via 8 chemicals: Chloroquine | Ciprofloxacin | Ethambutol | Folic Acid | Methotrexate | Phenytoin | Quinidine | Smoke   20
20. vasodilation Color Vision Defects Inferred via 8 chemicals: Amiodarone | Cocaine | Ibuprofen | Minoxidil | Quinidine | Ranitidine | Smoke | Tamoxifen   27
21. membrane lipid catabolic process Retinal Degeneration Inferred via 8 chemicals: Deferoxamine | Edaravone | Iron | Niacin | Paraquat | Rotenone | Thioridazine | Zinc   72
22. membrane lipid catabolic process Color Vision Defects Inferred via 8 chemicals: Amiodarone | Cocaine | Deferoxamine | Ibuprofen | Quinidine | Smoke | Tamoxifen | Thioridazine   62
23. regulation of heart rate Color Vision Defects Inferred via 8 chemicals: Amiodarone | Cocaine | Digoxin | Ibuprofen | Minoxidil | Quinidine | Ranitidine | Smoke   81
24. positive regulation of superoxide dismutase activity Retinal Degeneration Inferred via 8 chemicals: Edaravone | mancozeb | Maneb | Methylene Blue | Paraquat | Rotenone | Vincristine | Zinc   22
25. lipid catabolic process Color Vision Defects Inferred via 8 chemicals: Amiodarone | Chloroquine | Ciprofloxacin | Cocaine | Ethambutol | Methotrexate | Quinidine | Ranitidine   21
26. response to oxidative stress Color Vision Defects Inferred via 8 chemicals: Amiodarone | Chloroquine | Cocaine | Deferoxamine | Quinidine | Smoke | Tamoxifen | Valproic Acid   33
27. response to oxidative stress Retinal Degeneration Inferred via 7 chemicals: Deferoxamine | Fenretinide | Iron | Niacin | Paraquat | Rotenone | Zinc Inferred via 2 genes: BCL2 | SOD1 43
28. apoptotic process Retinoblastoma Inferred via 7 chemicals: Arsenic Trioxide | Calcitriol | Carboplatin | Cyclophosphamide | Etoposide | Methylnitrosourea | SN50 peptide Inferred via 1 gene: RB1 287
29. regulation of mitochondrial membrane potential Color Vision Defects Inferred via 7 chemicals: Amiodarone | Ciprofloxacin | Cocaine | Deferoxamine | Phenytoin | Tamoxifen | Valproic Acid   22
30. cell proliferation Retinoblastoma Inferred via 7 chemicals: Arsenic Trioxide | Calcitriol | Carboplatin | Cyclophosphamide | Etoposide | Methylnitrosourea | SN50 peptide   193
31. superoxide dismutase activity Color Vision Defects Inferred via 7 chemicals: Amiodarone | Chloroquine | Cocaine | Ethambutol | Methotrexate | Ranitidine | Smoke   23
32. cell differentiation Color Vision Defects Inferred via 7 chemicals: Chloroquine | Cocaine | Deferoxamine | Digoxin | Minoxidil | Quinidine | Valproic Acid   22
33. glutathione metabolic process Color Vision Defects Inferred via 7 chemicals: Carbamazepine | Clioquinol | Deferoxamine | Ibuprofen | Methotrexate | Tamoxifen | Valproic Acid   22
34. vasoconstriction Color Vision Defects Inferred via 7 chemicals: Amiodarone | Cocaine | Digoxin | Ibuprofen | Quinidine | Ranitidine | Smoke   46
35. positive regulation of cell proliferation Retinal Degeneration Inferred via 6 chemicals: 4,4'-diaminodiphenylmethane | Fenretinide | Iron | Paraquat | Vincristine | Zinc Inferred via 2 genes: BCL2 | GDNF 19
36. positive regulation of mitochondrial membrane potential Retinal Degeneration Inferred via 6 chemicals: Paraquat | Retinaldehyde | Rotenone | Thioridazine | Vincristine | Zinc   24
37. detection of oxidative stress Color Vision Defects Inferred via 6 chemicals: Amiodarone | Carbamazepine | Phenytoin | Ranitidine | Tamoxifen | Valproic Acid   11
38. apoptotic DNA fragmentation Color Vision Defects Inferred via 6 chemicals: Amiodarone | Chloroquine | Cocaine | Ibuprofen | Smoke | Valproic Acid   21
39. drug metabolic process Color Vision Defects Inferred via 6 chemicals: Carbamazepine | Folic Acid | Phenytoin | Quinidine | Valproic Acid | Vigabatrin   12
40. apoptotic process Retinitis Pigmentosa Inferred via 6 chemicals: alpha-Tocopherol | Ascorbic Acid | Deferoxamine | manganese(III)-tetrakis(4-benzoic acid)porphyrin | Tamoxifen | Thioctic Acid   100
41. positive regulation of glutathione peroxidase activity Retinal Degeneration Inferred via 6 chemicals: Edaravone | Iron | Maneb | Paraquat | Vincristine | Zinc   17
42. protein oxidation Retinal Degeneration Inferred via 6 chemicals: Iron | Maneb | Paraquat | Rotenone | Zinc | Ziram   17
43. cell death Retinitis Pigmentosa Inferred via 6 chemicals: alpha-Tocopherol | Ascorbic Acid | Deferoxamine | manganese(III)-tetrakis(4-benzoic acid)porphyrin | Tamoxifen | Thioctic Acid   66
44. positive regulation of cell death Retinitis Pigmentosa Inferred via 6 chemicals: alpha-Tocopherol | Ascorbic Acid | Deferoxamine | manganese(III)-tetrakis(4-benzoic acid)porphyrin | Tamoxifen | Thioctic Acid   20
45. membrane lipid catabolic process Retinitis Pigmentosa Inferred via 6 chemicals: alpha-Tocopherol | Ascorbic Acid | Deferoxamine | manganese(III)-tetrakis(4-benzoic acid)porphyrin | Tamoxifen | Thioctic Acid   141
46. lipid catabolic process Retinal Degeneration Inferred via 6 chemicals: Iron | Niacin | Ofloxacin | Paraquat | Rotenone | Zinc   48
47. reactive oxygen species metabolic process Retinal Degeneration Inferred via 5 chemicals: Deferoxamine | Edaravone | Hydrocarbons, Chlorinated | Paraquat | Rotenone Inferred via 2 genes: BCL2 | SOD1 34
48. positive regulation of apoptotic process Retinitis Pigmentosa Inferred via 5 chemicals: alpha-Tocopherol | Ascorbic Acid | Deferoxamine | manganese(III)-tetrakis(4-benzoic acid)porphyrin | Tamoxifen Inferred via 1 gene: ATF6 20
49. cell cycle Retinoblastoma Inferred via 5 chemicals: Arsenic Trioxide | Calcitriol | Carboplatin | Cyclophosphamide | Etoposide Inferred via 1 gene: RB1 51
50. glutathione metabolic process Retinitis Pigmentosa Inferred via 5 chemicals: alpha-Tocopherol | Ascorbic Acid | Deferoxamine | Tamoxifen | Thioctic Acid   16
1–50 of 15,287 results.