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Disease Eye Diseases, Hereditary

These phenotypes are associated with Eye Diseases, Hereditary or its descendants. A phenotype has an inferred association via a curated chemical interaction or a gene-GO annotation or both.

1–50 of 15,346 results.
  Phenotype Disease Chemical Inference Network Gene Inference Network References
1. apoptotic process Color Vision Defects Inferred via 18 chemicals: Amiodarone | Chloroquine | Ciprofloxacin | Clioquinol | Cocaine | Deferoxamine | Digoxin | Folic Acid | Ibuprofen | Methotrexate | Minoxidil | Phenytoin | Quinidine | Ranitidine | Ribavirin | Smoke | Tamoxifen | Valproic Acid   154
2. cell proliferation Color Vision Defects Inferred via 17 chemicals: Amiodarone | Chloroquine | Ciprofloxacin | Clioquinol | Cocaine | Deferoxamine | Folic Acid | Ibuprofen | Methotrexate | Minoxidil | Phenytoin | Quinidine | Ranitidine | Ribavirin | Smoke | Tamoxifen | Valproic Acid   133
3. cell proliferation Retinal Degeneration Inferred via 15 chemicals: Deferoxamine | Edaravone | Fenretinide | Hydrocarbons, Chlorinated | Iron | mancozeb | Maneb | Methylnitrosourea | Ofloxacin | Paraquat | Rotenone | tauroursodeoxycholic acid | Vincristine | Zinc | Ziram Inferred via 2 genes: BCL2 | GDNF 78
4. cell death Color Vision Defects Inferred via 15 chemicals: Amiodarone | Carbamazepine | Chloroquine | Clioquinol | Cocaine | Deferoxamine | Digoxin | Ibuprofen | Methotrexate | Phenytoin | Quinidine | Ribavirin | Smoke | Tamoxifen | Valproic Acid   97
5. apoptotic process Retinal Degeneration Inferred via 14 chemicals: Deferoxamine | Edaravone | Fenretinide | Iron | Maneb | Methylnitrosourea | Niacin | Ofloxacin | Paraquat | Rotenone | tauroursodeoxycholic acid | Vincristine | Zinc | Ziram Inferred via 1 gene: BCL2 141
6. positive regulation of cell death Color Vision Defects Inferred via 14 chemicals: Amiodarone | Carbamazepine | Chloroquine | Clioquinol | Deferoxamine | Digoxin | Folic Acid | Ibuprofen | Methotrexate | Phenytoin | Smoke | Tamoxifen | Thioridazine | Valproic Acid   68
7. cell death Retinal Degeneration Inferred via 13 chemicals: 9-cis-retinal | Deferoxamine | Fenretinide | Iron | mancozeb | Maneb | Methylnitrosourea | Ofloxacin | Paraquat | Rotenone | tauroursodeoxycholic acid | Vincristine | Zinc   116
8. positive regulation of cell death Retinal Degeneration Inferred via 12 chemicals: Deferoxamine | Fenretinide | Hydrocarbons, Chlorinated | mancozeb | Maneb | Niacin | Paraquat | Retinaldehyde | Rotenone | Thioridazine | Vincristine | Zinc   63
9. regulation of mitochondrial membrane potential Retinal Degeneration Inferred via 11 chemicals: Deferoxamine | Edaravone | Fenretinide | Iron | Methylene Blue | Paraquat | Rotenone | tauroursodeoxycholic acid | Vincristine | Zinc | Ziram Inferred via 2 genes: BCL2 | SOD1 48
10. regulation of blood pressure Color Vision Defects Inferred via 11 chemicals: Chloroquine | Cocaine | Digoxin | Folic Acid | Ibuprofen | Linezolid | Minoxidil | Quinidine | Ranitidine | Smoke | Valproic Acid   87
11. positive regulation of apoptotic process Retinal Degeneration Inferred via 10 chemicals: Deferoxamine | Edaravone | mancozeb | Paraquat | Retinaldehyde | Rotenone | tauroursodeoxycholic acid | Vincristine | Zinc | Ziram Inferred via 1 gene: SOD1 42
12. glutathione metabolic process Retinal Degeneration Inferred via 9 chemicals: Deferoxamine | Edaravone | Fenretinide | mancozeb | Maneb | Paraquat | Rotenone | Vincristine | Zinc Inferred via 1 gene: SOD1 30
13. positive regulation of reactive oxygen species biosynthetic process Retinal Degeneration Inferred via 9 chemicals: Deferoxamine | Edaravone | Fenretinide | Iron | mancozeb | Paraquat | Retinaldehyde | Rotenone | Zinc   48
14. lipid oxidation Retinal Degeneration Inferred via 9 chemicals: Edaravone | Iron | mancozeb | Maneb | Methylene Blue | Paraquat | Rotenone | Vincristine | Zinc   34
15. glutathione biosynthetic process Color Vision Defects Inferred via 9 chemicals: Chloroquine | Ciprofloxacin | Cocaine | Ethambutol | Folic Acid | Methotrexate | Phenytoin | Quinidine | Smoke   22
16. cell cycle Color Vision Defects Inferred via 9 chemicals: Chloroquine | Ciprofloxacin | Cocaine | Deferoxamine | Ibuprofen | Methotrexate | Quinidine | Tamoxifen | Valproic Acid   36
17. positive regulation of apoptotic process Color Vision Defects Inferred via 8 chemicals: Amiodarone | Carbamazepine | Chloroquine | Deferoxamine | Ibuprofen | Methotrexate | Tamoxifen | Valproic Acid Inferred via 1 gene: ATF6 48
18. membrane lipid catabolic process Color Vision Defects Inferred via 8 chemicals: Amiodarone | Cocaine | Deferoxamine | Ibuprofen | Quinidine | Smoke | Tamoxifen | Thioridazine   62
19. response to oxidative stress Color Vision Defects Inferred via 8 chemicals: Amiodarone | Chloroquine | Cocaine | Deferoxamine | Quinidine | Smoke | Tamoxifen | Valproic Acid   33
20. vasodilation Color Vision Defects Inferred via 8 chemicals: Amiodarone | Cocaine | Ibuprofen | Minoxidil | Quinidine | Ranitidine | Smoke | Tamoxifen   27
21. regulation of heart rate Color Vision Defects Inferred via 8 chemicals: Amiodarone | Cocaine | Digoxin | Ibuprofen | Minoxidil | Quinidine | Ranitidine | Smoke   81
22. lipid catabolic process Color Vision Defects Inferred via 8 chemicals: Amiodarone | Chloroquine | Ciprofloxacin | Cocaine | Ethambutol | Methotrexate | Quinidine | Ranitidine   22
23. DNA damage response, detection of DNA damage Retinal Degeneration Inferred via 8 chemicals: Deferoxamine | mancozeb | Maneb | Methylene Blue | Methylnitrosourea | Paraquat | Rotenone | Zinc   26
24. glutathione metabolic process Color Vision Defects Inferred via 8 chemicals: Carbamazepine | Clioquinol | Deferoxamine | Folic Acid | Ibuprofen | Methotrexate | Tamoxifen | Valproic Acid   23
25. membrane lipid catabolic process Retinal Degeneration Inferred via 8 chemicals: Deferoxamine | Edaravone | Iron | Niacin | Paraquat | Rotenone | Thioridazine | Zinc   72
26. positive regulation of superoxide dismutase activity Retinal Degeneration Inferred via 8 chemicals: Edaravone | mancozeb | Maneb | Methylene Blue | Paraquat | Rotenone | Vincristine | Zinc   22
27. reactive oxygen species biosynthetic process Color Vision Defects Inferred via 8 chemicals: Amiodarone | Chloroquine | Ciprofloxacin | Cocaine | Deferoxamine | Smoke | Tamoxifen | Valproic Acid   22
28. response to oxidative stress Retinal Degeneration Inferred via 7 chemicals: Deferoxamine | Fenretinide | Iron | Niacin | Paraquat | Rotenone | Zinc Inferred via 2 genes: BCL2 | SOD1 44
29. apoptotic process Retinoblastoma Inferred via 7 chemicals: Arsenic Trioxide | Calcitriol | Carboplatin | Cyclophosphamide | Etoposide | Methylnitrosourea | SN50 peptide Inferred via 1 gene: RB1 288
30. protein oxidation Retinal Degeneration Inferred via 7 chemicals: Iron | mancozeb | Maneb | Paraquat | Rotenone | Zinc | Ziram   20
31. reactive oxygen species biosynthetic process Retinal Degeneration Inferred via 7 chemicals: Deferoxamine | Iron | Maneb | Paraquat | Rotenone | tauroursodeoxycholic acid | Ziram   42
32. cell growth Color Vision Defects Inferred via 7 chemicals: Carbamazepine | Chloroquine | Cocaine | Methotrexate | Ribavirin | Tamoxifen | Valproic Acid   21
33. superoxide dismutase activity Color Vision Defects Inferred via 7 chemicals: Amiodarone | Chloroquine | Cocaine | Ethambutol | Methotrexate | Ranitidine | Smoke   23
34. cell differentiation Color Vision Defects Inferred via 7 chemicals: Chloroquine | Cocaine | Deferoxamine | Digoxin | Minoxidil | Quinidine | Valproic Acid   22
35. vasoconstriction Color Vision Defects Inferred via 7 chemicals: Amiodarone | Cocaine | Digoxin | Ibuprofen | Quinidine | Ranitidine | Smoke   46
36. lipid catabolic process Retinal Degeneration Inferred via 7 chemicals: Iron | mancozeb | Niacin | Ofloxacin | Paraquat | Rotenone | Zinc   53
37. cell proliferation Retinoblastoma Inferred via 7 chemicals: Arsenic Trioxide | Calcitriol | Carboplatin | Cyclophosphamide | Etoposide | Methylnitrosourea | SN50 peptide   194
38. regulation of mitochondrial membrane potential Color Vision Defects Inferred via 7 chemicals: Amiodarone | Ciprofloxacin | Cocaine | Deferoxamine | Phenytoin | Tamoxifen | Valproic Acid   22
39. positive regulation of cell proliferation Retinal Degeneration Inferred via 6 chemicals: 4,4'-diaminodiphenylmethane | Fenretinide | Iron | Paraquat | Vincristine | Zinc Inferred via 2 genes: BCL2 | GDNF 19
40. positive regulation of cell proliferation Color Vision Defects Inferred via 6 chemicals: Amiodarone | Chloroquine | Folic Acid | Methotrexate | Tamoxifen | Valproic Acid   17
41. apoptotic process Retinitis Pigmentosa Inferred via 6 chemicals: alpha-Tocopherol | Ascorbic Acid | Deferoxamine | manganese(III)-tetrakis(4-benzoic acid)porphyrin | Tamoxifen | Thioctic Acid   102
42. lipid oxidation Color Vision Defects Inferred via 6 chemicals: Carbamazepine | Clioquinol | Folic Acid | Ibuprofen | Methotrexate | Tamoxifen   18
43. positive regulation of cell death Retinitis Pigmentosa Inferred via 6 chemicals: alpha-Tocopherol | Ascorbic Acid | Deferoxamine | manganese(III)-tetrakis(4-benzoic acid)porphyrin | Tamoxifen | Thioctic Acid   20
44. DNA damage response, detection of DNA damage Color Vision Defects Inferred via 6 chemicals: Cocaine | Deferoxamine | Ethambutol | Phenytoin | Tamoxifen | Valproic Acid   17
45. cell death Retinitis Pigmentosa Inferred via 6 chemicals: alpha-Tocopherol | Ascorbic Acid | Deferoxamine | manganese(III)-tetrakis(4-benzoic acid)porphyrin | Tamoxifen | Thioctic Acid   68
46. membrane lipid catabolic process Retinitis Pigmentosa Inferred via 6 chemicals: alpha-Tocopherol | Ascorbic Acid | Deferoxamine | manganese(III)-tetrakis(4-benzoic acid)porphyrin | Tamoxifen | Thioctic Acid   141
47. apoptotic DNA fragmentation Color Vision Defects Inferred via 6 chemicals: Amiodarone | Chloroquine | Cocaine | Ibuprofen | Smoke | Valproic Acid   21
48. positive regulation of glutathione peroxidase activity Retinal Degeneration Inferred via 6 chemicals: Edaravone | Iron | Maneb | Paraquat | Vincristine | Zinc   17
49. detection of oxidative stress Color Vision Defects Inferred via 6 chemicals: Amiodarone | Carbamazepine | Phenytoin | Ranitidine | Tamoxifen | Valproic Acid   11
50. cell death Retinoblastoma Inferred via 6 chemicals: Arsenic Trioxide | Calcitriol | Carboplatin | Etoposide | Methylnitrosourea | SN50 peptide   55
1–50 of 15,346 results.