These are exposure studies associated with the disease and all of its children.
|Reference||Associated Study Title||Author's Summary||Study Factors||Stressor||Receptors||Country||Medium||Exposure Marker||Measurements||Outcome|
|1.||Ward-Caviness CK, et al. (2016).||CATHeterization GENetics (CATHGEN)||Our results reveal a novel gene (and possibly gene family) associated with peripheral arterial disease, via an interaction with traffic air pollution exposure; these results highlight the potential for interactions studies, particularly at the genome scale, to reveal novel biology linking environmental exposures to clinical outcomes.||genetics||Air Pollutants | Vehicle Emissions||Subjects with gene influence:BMP2 | Subjects with gene influence:BMP8A||United States||Details||Peripheral Arterial Disease|
|2.||D'Ippoliti D, et al. (2015).||Results provide new evidence for risk assessment of low-medium concentrations of arsenic and contribute to the ongoing debate about the threshold-dose of effect, suggesting that even concentrations below 10 micrograms per liter carry a mortality risk.||sex||Arsenic||Study subjects||Italy||Arsenic||Details||Death | Diabetes Mellitus | Lung Neoplasms | Myocardial Infarction | Peripheral Arterial Disease | Pulmonary Disease, Chronic Obstructive|
|3.||Chen CJ, et al. (1996).||In this study, we observed a significantly increased ischemic heart disease (ISHD) mortality among residents in the blackfoot disease (BFD)-endemic area, a significantly higher ISHD mortality for BFD patients than for age-, sex-, and residence-matched control subjects, and a dose-response relation between ISHD mortality and long-term exposure to ingested inorganic arsenic.||age | disease||Arsenic||Controls for disease:Peripheral Vascular Diseases | Subjects with disease:Peripheral Vascular Diseases | Study subjects||Taiwan, Province of China||water, drinking||Arsenic||Details||Death | Myocardial Ischemia|
|4.||Shankar A, et al. (2012).||National Health and Nutrition Examination Survey (NHANES)||Urinary bisphenol A levels were significantly associated with peripheral arterial disease, independent of traditional cardiovascular disease risk factors.||race | sex | tobacco||bisphenol A||Study subjects||United States||urine||bisphenol A||Details||Peripheral Arterial Disease|
|5.||Tellez-Plaza M, et al. (2010).||National Health and Nutrition Examination Survey (NHANES)||In this representative sample of the US population, high cadmium levels were associated with an increased prevalence of Peripheral Artery Disease (PAD), but the association between cadmium and PAD at low cadmium exposures was markedly different in men and women.||sex||Cadmium | Cotinine | Lead||Controls for disease:Peripheral Arterial Disease | Subjects with disease:Peripheral Arterial Disease | Study subjects||United States||blood | serum | urine||Cadmium | Cotinine | Lead||Details||Peripheral Arterial Disease|