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Disease Severe Combined Immunodeficiency

Name Severe Combined Immunodeficiency
Synonyms Bare Lymphocyte Syndrome | Bare Lymphocyte Syndromes | Combined Immunodeficiencies, Severe | Combined Immunodeficiency, Severe | Familial Reticuloendothelioses | Familial Reticuloendotheliosis | Immunodeficiencies, Severe Combined | Immunodeficiency, Severe Combined | Immunodeficiency Syndrome, Severe Combined | Immunologic Deficiency, Severe Combined | Lymphocyte Syndrome, Bare | Lymphocyte Syndromes, Bare | Omenn's Syndrome | Omenns Syndrome | Omenn Syndrome | Reticuloendothelioses, Familial | Reticuloendotheliosis, Familial | Severe Combined Immune Deficiency | Severe Combined Immunodeficiencies | Severe Combined Immunodeficiency Syndrome | Severe Combined Immunologic Deficiency | Syndrome, Bare Lymphocyte | Syndrome, Omenn | Syndrome, Omenn's | Syndromes, Bare Lymphocyte
Definition Group of rare congenital disorders characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels. It is inherited as an X-linked or autosomal recessive defect. Mutations occurring in many different genes cause human Severe Combined Immunodeficiency (SCID).
Categories Immune system disease | Infant-newborn disease | Metabolic disease
MeSH® ID D016511
External Links

Top ↑ Ancestors

1. DiseasesCongenital, Hereditary, and Neonatal Diseases and Abnormalities Has associated chemicals Has associated genes Has associated exposure references Infant, Newborn, Diseases Has associated chemicals Has associated genes Has associated exposure references Severe Combined Immunodeficiency Has associated chemicals Has associated genes
2. DiseasesNutritional and Metabolic Diseases Has associated chemicals Has associated genes Has associated exposure references Metabolic Diseases Has associated chemicals Has associated genes Has associated exposure references DNA Repair-Deficiency Disorders Has associated chemicals Has associated genes Severe Combined Immunodeficiency Has associated chemicals Has associated genes
3. DiseasesImmune System Diseases Has associated chemicals Has associated genes Has associated exposure references Immunologic Deficiency Syndromes Has associated chemicals Has associated genes Severe Combined Immunodeficiency Has associated chemicals Has associated genes

Top ↑ Descendants

Severe Combined Immunodeficiency Has associated chemicals Has associated genes
  Athabaskan severe combined immunodeficiency
  Bare lymphocyte syndrome 2 Has associated chemicals Has associated genes
  Bare Lymphocyte Syndrome, Type I Has associated chemicals Has associated genes
  Bare Lymphocyte Syndrome, Type II, Complementation Group A
  Combined Cellular And Humoral Immune Defects With Granulomas Has associated chemicals Has associated genes
  HLA class 1 deficiency
  Immune dysfunction with T-cell inactivation due to calcium entry defect 1 Has associated chemicals Has associated genes
  Immune dysfunction with T-cell inactivation due to calcium entry defect 2 Has associated chemicals Has associated genes
  Reticular dysgenesis Has associated chemicals Has associated genes
  Reticuloendotheliosis, familial, with eosinophilia Has associated chemicals Has associated genes
  Reticuloendotheliosis, X-linked
  Severe combined immunodeficiency, atypical
  Severe Combined Immunodeficiency, Autosomal Recessive, T Cell-Negative, B Cell-Positive, NK Cell-Negative Has associated chemicals Has associated genes
  Severe Combined Immunodeficiency, Autosomal Recessive, T Cell Negative, B Cell Positive, NK Cell Positive Has associated chemicals Has associated genes
  Severe combined immunodeficiency due to adenosine deaminase deficiency Has associated chemicals Has associated genes
  Severe Combined Immunodeficiency with Microcephaly, Growth Retardation, and Sensitivity to Ionizing Radiation Has associated chemicals Has associated genes
  Severe combined immunodeficiency with sensitivity to ionizing radiation Has associated chemicals Has associated genes
  Short-Limb Skeletal Dysplasia with Severe Combined Immunodeficiency
  T-cell immunodeficiency, congenital alopecia and nail dystrophy Has associated chemicals Has associated genes
View node X-Linked Combined Immunodeficiency Diseases Has associated chemicals Has associated genes
  ZAP70 deficiency