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Disease MELAS Syndrome

Name MELAS Syndrome
Synonyms MELAS | MELAS SYNDROME | Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-Like Episodes | Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, And Stroke-Like Episodes | Mitochondrial Myopathy, Lactic Acidosis, Stroke-Like Episode | Myopathy, Mitochondrial-Encephalopathy-Lactic Acidosis-Stroke | Syndrome, MELAS
Definition A mitochondrial disorder characterized by focal or generalized seizures, episodes of transient or persistent neurologic dysfunction resembling strokes, and ragged-red fibers on muscle biopsy. Affected individuals tend to be normal at birth through early childhood, then experience growth failure, episodic vomiting, and recurrent cerebral insults resulting in visual loss and hemiparesis. The cortical lesions tend to occur in the parietal and occipital lobes and are not associated with vascular occlusion. VASCULAR HEADACHE is frequently associated and the disorder tends to be familial. (From Joynt, Clinical Neurology, 1992, Ch56, p117)
Categories Cardiovascular disease | Genetic disease (inborn) | Metabolic disease | Musculoskeletal disease | Nervous system disease
MeSH® ID D017241
OMIM® ID 540000
External Links

Top ↑ Ancestors

1. DiseasesMusculoskeletal Diseases Has associated chemicals Has associated genes Has associated exposure references Muscular Diseases Has associated chemicals Has associated genes Mitochondrial Myopathies Has associated chemicals Has associated genes Mitochondrial Encephalomyopathies Has associated chemicals Has associated genes MELAS Syndrome Has associated chemicals Has associated genes
2. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Central Nervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Brain Diseases Has associated chemicals Has associated genes Has associated exposure references Brain Diseases, Metabolic Has associated chemicals Has associated genes Brain Diseases, Metabolic, Inborn Has associated chemicals Has associated genes MELAS Syndrome Has associated chemicals Has associated genes
3. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Central Nervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Brain Diseases Has associated chemicals Has associated genes Has associated exposure references Cerebrovascular Disorders Has associated chemicals Has associated genes Has associated exposure references Cerebral Small Vessel Diseases Has associated chemicals Has associated genes MELAS Syndrome Has associated chemicals Has associated genes
4. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Neuromuscular Diseases Has associated chemicals Has associated genes Has associated exposure references Muscular Diseases Has associated chemicals Has associated genes Mitochondrial Myopathies Has associated chemicals Has associated genes Mitochondrial Encephalomyopathies Has associated chemicals Has associated genes MELAS Syndrome Has associated chemicals Has associated genes
5. DiseasesCardiovascular Diseases Has associated chemicals Has associated genes Has associated exposure references Vascular Diseases Has associated chemicals Has associated genes Has associated exposure references Cerebrovascular Disorders Has associated chemicals Has associated genes Has associated exposure references Cerebral Small Vessel Diseases Has associated chemicals Has associated genes MELAS Syndrome Has associated chemicals Has associated genes
6. DiseasesCongenital, Hereditary, and Neonatal Diseases and Abnormalities Has associated chemicals Has associated genes Has associated exposure references Genetic Diseases, Inborn Has associated chemicals Has associated genes Has associated exposure references Metabolism, Inborn Errors Has associated chemicals Has associated genes Has associated exposure references Brain Diseases, Metabolic, Inborn Has associated chemicals Has associated genes MELAS Syndrome Has associated chemicals Has associated genes
7. DiseasesNutritional and Metabolic Diseases Has associated chemicals Has associated genes Has associated exposure references Metabolic Diseases Has associated chemicals Has associated genes Has associated exposure references Brain Diseases, Metabolic Has associated chemicals Has associated genes Brain Diseases, Metabolic, Inborn Has associated chemicals Has associated genes MELAS Syndrome Has associated chemicals Has associated genes
8. DiseasesNutritional and Metabolic Diseases Has associated chemicals Has associated genes Has associated exposure references Metabolic Diseases Has associated chemicals Has associated genes Has associated exposure references Metabolism, Inborn Errors Has associated chemicals Has associated genes Has associated exposure references Brain Diseases, Metabolic, Inborn Has associated chemicals Has associated genes MELAS Syndrome Has associated chemicals Has associated genes
9. DiseasesNutritional and Metabolic Diseases Has associated chemicals Has associated genes Has associated exposure references Metabolic Diseases Has associated chemicals Has associated genes Has associated exposure references Mitochondrial Diseases Has associated chemicals Has associated genes Mitochondrial Myopathies Has associated chemicals Has associated genes Mitochondrial Encephalomyopathies Has associated chemicals Has associated genes MELAS Syndrome Has associated chemicals Has associated genes

Top ↑ Descendants

MELAS Syndrome Has associated chemicals Has associated genes
  Myopathy with lactic acidosis and sideroblastic anemia Has associated chemicals Has associated genes