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Disease Polymyositis

Name Polymyositis
Synonyms Idiopathic Polymyositides | Idiopathic Polymyositis | Multiple Myositis | Myositides, Multiple | Myositis, Multiple | Ossificans, Polymyositis | Polymyositides | Polymyositides, Idiopathic | Polymyositis, Idiopathic | Polymyositis Ossificans
Definition Diseases characterized by inflammation involving multiple muscles. This may occur as an acute or chronic condition associated with medication toxicity (DRUG TOXICITY); CONNECTIVE TISSUE DISEASES; infections; malignant NEOPLASMS; and other disorders. The term polymyositis is frequently used to refer to a specific clinical entity characterized by subacute or slowly progressing symmetrical weakness primarily affecting the proximal limb and trunk muscles. The illness may occur at any age, but is most frequent in the fourth to sixth decade of life. Weakness of pharyngeal and laryngeal muscles, interstitial lung disease, and inflammation of the myocardium may also occur. Muscle biopsy reveals widespread destruction of segments of muscle fibers and an inflammatory cellular response. (Adams et al., Principles of Neurology, 6th ed, pp1404-9)
Categories Musculoskeletal disease | Nervous system disease
MeSH® ID D017285

Top ↑ Ancestors

1. DiseasesMusculoskeletal Diseases Has associated chemicals Has associated genes Has associated exposure references Muscular Diseases Has associated chemicals Has associated genes Myositis Has associated chemicals Has associated genes Polymyositis Has associated chemicals Has associated genes
2. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Neuromuscular Diseases Has associated chemicals Has associated genes Has associated exposure references Muscular Diseases Has associated chemicals Has associated genes Myositis Has associated chemicals Has associated genes Polymyositis Has associated chemicals Has associated genes

Top ↑ Descendants

Polymyositis Has associated chemicals Has associated genes
View node Dermatomyositis Has associated chemicals Has associated genes