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Disease Skin and Connective Tissue Diseases

These phenotypes are associated with Skin and Connective Tissue Diseases or its descendants. A phenotype has an inferred association via a curated chemical interaction or a gene-GO annotation or both.

1–50 of 113,483 results.
  Phenotype Disease Chemical Inference Network Gene Inference Network References
1. cell proliferation Breast Neoplasms Inferred via 206 chemicals: 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin | 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine | 2,4,5,2',4',5'-hexachlorobiphenyl | 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine | 2-chloro-5-nitrobenzanilide | 2-Methoxyestradiol | 3,3',4,5'-tetrahydroxystilbene | 3,3'-diindolylmethane | 3,5-bis(2-fluorobenzylidene)piperidin-4-one | 4-biphenylamine | 4-hydroxyestradiol | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | 4-nonylphenol | 7-hydroxystaurosporine | 9,10-Dimethyl-1,2-benzanthracene | ado-trastuzumab emtansine | Alitretinoin | allyl sulfide | alvocidib | Amifostine | Anastrozole | Androgens | anthracene | Apigenin | Arsenic | Arsenic Trioxide | Ascorbic Acid | Aspirin | Atrazine | Atropine | aurapten | Benzene | Benzo(a)pyrene | beta-Naphthoflavone | betulinic acid | bicalutamide | bisphenol A | Bortezomib | Bromodeoxyuridine | Busulfan | Butylated Hydroxyanisole | Cacodylic Acid | Cadmium | Caffeine | Calcitriol | Canertinib | Capecitabine | Capsaicin | Carboplatin | Carmustine | Catechin | Celecoxib | Chalcones | Chloroquine | Chlorpyrifos | Ciclopirox | Cisplatin | Clioquinol | Clomiphene | Cobalt | Copper | Curcumin | Cyclophosphamide | Cyclosporine | Cytarabine | dactolisib | Dasatinib | DDT | Decitabine | Deferoxamine | deguelin | Deoxyglucose | Dexamethasone | diallyl trisulfide | Dichlorodiphenyl Dichloroethylene | Dieldrin | Dietary Fats | Diethylhexyl Phthalate | Diethylnitrosamine | diethyl phthalate | Diethylstilbestrol | Diltiazem | Dinoprostone | Disulfiram | Docetaxel | doxifluridine | Doxorubicin | epigallocatechin gallate | Estradiol | Estrogens | Ethanol | Etoposide | Eugenol | Fenretinide | Fluorouracil | Folic Acid | Formaldehyde | Fulvestrant | Gefitinib | gemcitabine | Genistein | gingerol | Hexachlorobenzene | Hydrocarbons, Chlorinated | Hydrocortisone | Ifosfamide | Imatinib Mesylate | indole-3-carbinol | Indomethacin | kaempferol | Lapatinib | Letrozole | Levamisole | Lignans | liposomal doxorubicin | Malathion | mancozeb | Manganese | mangostin | Masoprocol | maxacalcitol | Medroxyprogesterone Acetate | Melphalan | Mesna | Methotrexate | Methoxychlor | Methylcholanthrene | Methylnitrosourea | Mitomycin | Mitoxantrone | mono-(2-ethylhexyl)phthalate | MRK 003 | N-(2-(4-((3-chloro-4-(3-(trifluoromethyl)phenoxy)phenyl)amino)-5H-pyrrolo(3,2-d)pyrimidin-5-yl)ethyl)-3-hydroxy-3-methylbutanamide | Nelfinavir | Nickel | Niclosamide | Nicotine | nimesulide | Nitric Oxide | Nitrofurazone | ochratoxin A | Oleic Acid | Organoselenium Compounds | Orlistat | Oxygen | Paclitaxel | palbociclib | Pamidronate | Parathion | Pemetrexed | perfluorodecanoic acid | perfluorohexanesulfonic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | Phytoestrogens | Plant Extracts | Plant Preparations | platycodin D | Polychlorinated Biphenyls | Polycyclic Aromatic Hydrocarbons | Prednisolone | Progesterone | Progestins | pterostilbene | pyrrolidine dithiocarbamic acid | Quercetin | Raloxifene Hydrochloride | Ranitidine | Razoxane | Reserpine | Resveratrol | Riboflavin | Rosiglitazone | RTKI cpd | salinomycin | seocalcitol | Smoke | Sorafenib | Sulfasalazine | Sulindac | Tamoxifen | tangeretin | tanshinone | temsirolimus | Testosterone | Tetrachlorodibenzodioxin | tipifarnib | Tobacco Smoke Pollution | Toremifene | Tretinoin | Trichloroethylene | valspodar | Vehicle Emissions | Verapamil | Vinblastine | Vincristine | Vindesine | Vinorelbine | Vitamin E | Vorinostat | Water Pollutants, Chemical | Wortmannin | xanthatin | xanthohumol | Zinc | Zoledronic Acid Inferred via 41 genes: ACHE | AKT1 | ALK | AR | AREG | BAX | BCL2 | BMP4 | BRCA2 | CD74 | CENPF | CSF1 | CSF1R | CTNNB1 | CUL5 | CYP1A1 | EGFR | ERBB2 | GNAI2 | GPX1 | HHEX | HRAS | IGF1 | MDM4 | MIF | MKI67 | MT3 | NRG1 | PDZK1 | PIM1 | PTEN | RAF1 | RPL23A | SRC | STAT3 | TNF | TOP2A | TP53 | TRP63 | YAP1 | ZEB1 2420
2. apoptotic process Breast Neoplasms Inferred via 187 chemicals: 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin | 2,2',3',4,4',5-hexachlorobiphenyl | 2,3-bis(3'-hydroxybenzyl)butyrolactone | 2,4,5,2',4',5'-hexachlorobiphenyl | 2-chloro-5-nitrobenzanilide | 2-Methoxyestradiol | 3,3'-diindolylmethane | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | 4-nonylphenol | 7-hydroxystaurosporine | Air Pollutants | Alitretinoin | alvocidib | Amifostine | Amsacrine | Apigenin | Arsenic | Arsenic Trioxide | Ascorbic Acid | Aspirin | Atrazine | Atropine | Benzo(a)pyrene | beta-Naphthoflavone | betulinic acid | Bexarotene | bicalutamide | bisphenol A | Bortezomib | Butylated Hydroxyanisole | Cadmium | Caffeine | Calcitriol | Canertinib | Capecitabine | Capsaicin | Carboplatin | Carmustine | Catechin | Celecoxib | Chalcones | Chloroquine | Chlorpyrifos | Chromium | Cisplatin | Clioquinol | Clomiphene | Cobalt | Copper | Curcumin | Cyclophosphamide | Cyclosporine | Cytarabine | Dacarbazine | dactolisib | Danazol | Dasatinib | DDT | Decitabine | Deferoxamine | deguelin | Deoxyglucose | Dexamethasone | diallyl trisulfide | Dichlorodiphenyl Dichloroethylene | Dicumarol | Dietary Fats | Diethylhexyl Phthalate | Diethylnitrosamine | Diethylstilbestrol | Diltiazem | Dinoprostone | Disulfiram | Docetaxel | Doxorubicin | Doxycycline | epicatechin gallate | epigallocatechin gallate | Epirubicin | Estradiol | Estrogens | Ethanol | Etoposide | Fenretinide | Fluorouracil | Folic Acid | Formaldehyde | Fulvestrant | Gefitinib | gemcitabine | Genistein | gingerol | Hexachlorobenzene | Hexachlorocyclohexane | Hydrocortisone | Imatinib Mesylate | indole-3-carbinol | Indomethacin | isoliquiritigenin | kaempferol | Lapatinib | Letrozole | Leucovorin | Levamisole | liposomal doxorubicin | Malathion | Manganese | mangostin | Masoprocol | Medroxyprogesterone Acetate | Melphalan | Methotrexate | Methylcholanthrene | methyleugenol | Methylnitrosourea | Mitomycin | Mitoxantrone | mono-(2-ethylhexyl)phthalate | MRK 003 | Nelfinavir | Niacin | Nickel | Niclosamide | Nicotine | nimesulide | Nitric Oxide | Nitrofurazone | Nitrogen Dioxide | Nitroglycerin | ochratoxin A | Oleic Acid | Orlistat | Oxygen | Paclitaxel | palbociclib | Pamidronate | parthenolide | Pemetrexed | perfluorooctane sulfonic acid | perfluorooctanoic acid | pirarubicin | Plant Extracts | Plant Preparations | Polychlorinated Biphenyls | Prednisolone | pregna-4,17-diene-3,16-dione | Progesterone | pyrrolidine dithiocarbamic acid | Quercetin | Raloxifene Hydrochloride | Ranitidine | Razoxane | Reserpine | Resveratrol | Riboflavin | Rosiglitazone | RTKI cpd | salinomycin | Selenium | seocalcitol | Smoke | Sorafenib | Sulfasalazine | Sulindac | Tamoxifen | tanshinone | temsirolimus | Testosterone | Tetrachlorodibenzodioxin | tipifarnib | Tobacco Smoke Pollution | Tretinoin | valspodar | Vehicle Emissions | Verapamil | Vinblastine | Vincristine | Vinorelbine | Vitamin D | Vitamin E | Vorinostat | Water Pollutants, Chemical | Wortmannin | xanthohumol | Zidovudine | Zinc | Zoledronic Acid Inferred via 63 genes: ABL1 | AHR | AKT1 | AKT2 | ATM | BAG1 | BAX | BCL2 | BCL2A1 | BIRC2 | BIRC5 | BRCA1 | C1QBP | CADM1 | CASP7 | CASP8 | CDKN2A | CHEK1 | CHEK2 | CXCR4 | DAP3 | DDIT3 | DIO3 | E2F1 | EP300 | EPB41L3 | FGFR2 | GJA1 | GPER1 | GPX1 | GZMB | HMOX1 | HRAS | IFNG | IL1B | IL24 | LSP1 | MAL | MAP2K7 | MECOM | MT3 | NFKBIA | NOTCH2 | NUDT2 | PAEP | PAK1 | PARP1 | PIM1 | PTEN | RAF1 | RB1 | SFRP2 | SFRP5 | SIRT1 | TNF | TNFSF10 | TOX3 | TP53 | TP73 | TRP53 | TRP63 | WT1 | WWOX 2907
3. cell death Breast Neoplasms Inferred via 154 chemicals: 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine | 2,4,5,2',4',5'-hexachlorobiphenyl | 2-chloro-5-nitrobenzanilide | 7-hydroxystaurosporine | 9,10-Dimethyl-1,2-benzanthracene | Acrylamide | Alitretinoin | alvocidib | Amifostine | Amsacrine | Anastrozole | Apigenin | Arsenic Trioxide | Ascorbic Acid | Aspirin | Atropine | Benzo(a)pyrene | betulinic acid | bisphenol A | Bortezomib | Busulfan | Butylated Hydroxyanisole | Cacodylic Acid | Cadmium | Caffeine | Calcitriol | Capsaicin | Carbamazepine | Carboplatin | Carmustine | Catechin | Celecoxib | Chalcone | Chloroquine | Chlorpyrifos | Ciclopirox | Cisplatin | Clioquinol | Cobalt | Copper | Curcumin | Cyclosporine | Cytarabine | Dacarbazine | dactolisib | Dapsone | Dasatinib | Decitabine | Deferoxamine | deguelin | Deoxyglucose | Dexamethasone | diallyl trisulfide | Dicumarol | Dieldrin | Dietary Fats | Diltiazem | Dinoprostone | Disulfiram | Docetaxel | doxifluridine | Doxorubicin | Doxycycline | Endocrine Disruptors | epigallocatechin gallate | Epirubicin | Estradiol | Estrogens | Ethanol | Etoposide | Eugenol | Fenretinide | Fluorouracil | Formaldehyde | Fulvestrant | Gefitinib | gemcitabine | Genistein | Hexachlorobenzene | Hexachlorocyclohexane | Imatinib Mesylate | Indomethacin | kaempferol | Letrozole | liposomal doxorubicin | mancozeb | Manganese | Masoprocol | Melphalan | Methotrexate | Methoxychlor | Mitomycin | Mitoxantrone | Nelfinavir | Nickel | Niclosamide | Nicotine | nimesulide | Nitric Oxide | Nitrogen Dioxide | ochratoxin A | Oleic Acid | Organoplatinum Compounds | Organoselenium Compounds | Orlistat | Oxygen | Paclitaxel | palbociclib | Pamidronate | perfluorodecanoic acid | perfluorohexanesulfonic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | pirarubicin | Plant Extracts | Plant Oils | platycodin D | Polycyclic Aromatic Hydrocarbons | Progesterone | pterostilbene | pyrrolidine dithiocarbamic acid | Quercetin | Quinine | Raloxifene Hydrochloride | Razoxane | Reserpine | Resveratrol | Rosiglitazone | salicylaldehyde isonicotinoyl hydrazone | salinomycin | Selenium | Smoke | Sorafenib | Sulindac | Tamoxifen | tangeretin | tanshinone | temsirolimus | Testosterone | Tetrachlorodibenzodioxin | Tobacco Smoke Pollution | Tretinoin | Trichloroethylene | Vehicle Emissions | Verapamil | Vinblastine | Vincristine | Vinorelbine | Vitamin E | Vorinostat | Wortmannin | xanthohumol | Zidovudine | Zinc Inferred via 2 genes: CDKN1B | HMOX1 1229
4. positive regulation of cell death Breast Neoplasms Inferred via 127 chemicals: 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine | 2-Methoxyestradiol | 3,3',4,5'-tetrahydroxystilbene | 3,5-bis(2-fluorobenzylidene)piperidin-4-one | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | 4-nonylphenol | Acrylamide | allyl sulfide | alvocidib | Antineoplastic Agents, Immunological | Apigenin | Arsenic | Arsenic Trioxide | Ascorbic Acid | Aspirin | Atrazine | Benzene | beta-Naphthoflavone | betulinic acid | Biological Products | bisphenol A | Bortezomib | Bromodeoxyuridine | Cadmium | Caffeine | Carbamazepine | Carboplatin | Carmustine | Catechin | Celecoxib | Chloroquine | Chlorpyrifos | Cisplatin | Clioquinol | Cobalt | Copper | Curcumin | Cyclophosphamide | Cyclosporine | Cytarabine | dactolisib | Dasatinib | Decitabine | Deferoxamine | deguelin | Deoxyglucose | Dexamethasone | Dichlorodiphenyl Dichloroethylene | Dicumarol | Diethylhexyl Phthalate | Disulfiram | Docetaxel | doramectin | Doxorubicin | ellipticine | epicatechin gallate | epigallocatechin gallate | Epirubicin | Estradiol | Ethanol | Etoposide | Fenretinide | Fluorouracil | Folic Acid | Formaldehyde | Fulvestrant | Gefitinib | gemcitabine | Genistein | Hydrocarbons, Chlorinated | Hydrocortisone | Ifosfamide | Imatinib Mesylate | indium phosphide | Indomethacin | isoliquiritigenin | kaempferol | mancozeb | Manganese | Masoprocol | Methotrexate | milbemycin | Mitomycin | Mitoxantrone | mono-(2-ethylhexyl)phthalate | Niacin | Nickel | Niclosamide | Nicotine | nimesulide | Nitric Oxide | ochratoxin A | Oxygen | Paclitaxel | Parathion | Pemetrexed | perfluorodecanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | pirarubicin | Plant Extracts | Plant Preparations | Polychlorinated Biphenyls | Polycyclic Aromatic Hydrocarbons | Prednisolone | pterostilbene | pyrrolidine dithiocarbamic acid | Quercetin | Raloxifene Hydrochloride | Reserpine | Resveratrol | Riboflavin | Rosiglitazone | salinomycin | Smoke | Tamoxifen | tanshinone | Tetrachlorodibenzodioxin | Tobacco Smoke Pollution | Tretinoin | valspodar | Vehicle Emissions | Verapamil | Vinblastine | Vincristine | Vinorelbine | Zinc Inferred via 12 genes: BMP4 | CDKN1B | DKK1 | DNMT3A | EP300 | GZMB | HP | IL1B | LPAR1 | MT3 | PHB | PTGS2 959
5. positive regulation of cell proliferation Breast Neoplasms Inferred via 110 chemicals: 2-hydroxyestradiol | 2-Methoxyestradiol | 3,3'-diindolylmethane | 4-hydroxyestradiol | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | 4-nonylphenol | 9,10-Dimethyl-1,2-benzanthracene | Acrylamide | Alitretinoin | allyl sulfide | Apigenin | Arsenic | Arsenic Trioxide | Ascorbic Acid | Aspirin | Atrazine | Benzo(a)pyrene | beta-Naphthoflavone | betulinic acid | bicalutamide | Biological Products | bisphenol A | Bortezomib | Butylated Hydroxyanisole | Calcitriol | Capsaicin | Carboplatin | Catechin | Chloroquine | Chlorpyrifos | Cisplatin | Copper | Curcumin | Cyclosporine | Cytarabine | Decitabine | Dexamethasone | diallyl trisulfide | Dichlorodiphenyl Dichloroethylene | Dieldrin | Dietary Fats | Diethylhexyl Phthalate | Diethylnitrosamine | Diethylstilbestrol | Disulfiram | doxifluridine | Doxorubicin | epigallocatechin gallate | Estradiol | Ethanol | Etoposide | Fenretinide | Fluorouracil | Folic Acid | Fulvestrant | gemcitabine | Genistein | gingerol | Imatinib Mesylate | isoliquiritigenin | kaempferol | Lapatinib | Manganese | Methotrexate | Methoxychlor | Methylene Chloride | methyleugenol | Mitomycin | Mitoxantrone | Nickel | Niclosamide | Nicotine | Nitric Oxide | ochratoxin A | Oxygen | Paclitaxel | Pemetrexed | perfluorooctanoic acid | pirarubicin | Plant Extracts | Plant Preparations | Polycyclic Aromatic Hydrocarbons | Progesterone | pterostilbene | Quercetin | Resveratrol | RTKI cpd | salinomycin | seocalcitol | Sorafenib | Styrene | Tamoxifen | Testosterone | Tetrachlorodibenzodioxin | Tetrachloroethylene | Tobacco Smoke Pollution | Toluene 2,4-Diisocyanate | Toxaphene | TPD7 compound | Tretinoin | Trichloroethylene | veliparib | Vinblastine | Vincristine | Vitamin E | Vorinostat | Water Pollutants, Chemical | Wortmannin | xanthatin | Zinc Inferred via 87 genes: ADAM10 | AKT1 | AKT2 | AR | AREG | BCL2 | BIRC5 | BMP4 | CCND1 | CDKN1B | CSF1 | CSF1R | CSF2 | CSF3 | CTNNB1 | CXCL12 | DLL1 | EDNRB | EFEMP1 | EGF | EGFR | EPOR | ERBB2 | EZH2 | FGF10 | FGF3 | FGF4 | FGFR1 | FGFR2 | FLT1 | FN1 | FOXM1 | GNAI2 | GPER1 | HES1 | HIF1A | HRAS | HSP90AA1 | IFNG | IGF1 | IGF1R | IL1B | IL24 | IL6 | JUN | KDR | KIT | KMT2D | KRAS | LEF1 | LEP | MDM2 | MDM4 | MFGE8 | MIR132 | MIR141 | MIR200B | MIR24-2 | NCOR1 | NOTCH1 | NOTCH2 | NRG1 | PAK1 | PDGFA | PGR | PLA2G4A | PRC1 | PTEN | PTGS2 | PTHLH | RAD51B | RARA | RARB | RELA | RPS4X | SFRP1 | SFRP2 | SIRT1 | STAT3 | STAT5A | TBX3 | THBS1 | TNF | VEGFC | WNT10B | YAP1 | YBX1 956
6. apoptotic process Stevens-Johnson Syndrome Inferred via 110 chemicals: 10-propargyl-10-deazaaminopterin | Acetaminophen | Acetazolamide | Alendronate | Allopurinol | Alprazolam | Amifostine | Amiodarone | Amoxicillin | Angiotensin-Converting Enzyme Inhibitors | Atorvastatin | Azithromycin | benazepril | Bortezomib | Carvedilol | Cefotaxime | Celecoxib | cerivastatin | Chlorambucil | Cilostazol | Ciprofloxacin | Citalopram | Cladribine | Clarithromycin | Clofarabine | Clozapine | Cyclophosphamide | Cyclosporine | Dactinomycin | Danazol | Diclofenac | Diltiazem | Docetaxel | Doxorubicin | Doxycycline | Enalapril | Erlotinib Hydrochloride | Etoposide | Fenofibrate | fludarabine | Fluoxetine | Gefitinib | Hydroxychloroquine | Ibuprofen | Indapamide | Indinavir | Indomethacin | Isotretinoin | Lansoprazole | Leflunomide | Letrozole | Levofloxacin | Lisinopril | Losartan | Lovastatin | Meloxicam | Methotrexate | Minocycline | montelukast | Naproxen | Nifedipine | Nitric Oxide | Ofloxacin | Omeprazole | Oxaprozin | Paclitaxel | Paroxetine | Pemetrexed | Penicillamine | Pentazocine | Phenobarbital | Phenytoin | Piroxicam | Pravastatin | Prednisolone | Propranolol | Propylthiouracil | Pyrimethamine | Quetiapine Fumarate | Ramipril | Ranitidine | repaglinide | Ribavirin | Rifampin | Ritonavir | rofecoxib | Rosiglitazone | Saquinavir | Sertraline | Simvastatin | Sitagliptin Phosphate | Sorafenib | Spironolactone | Sulfasalazine | Sulindac | Tacrolimus | Tadalafil | Tamoxifen | Temozolomide | temsirolimus | teriflunomide | Thalidomide | Ticlopidine | Tramadol | Valproic Acid | Vancomycin | Vemurafenib | Venlafaxine Hydrochloride | Verapamil | Zidovudine Inferred via 8 genes: CUL1 | ELMO1 | EP300 | IFNA2 | IFNG | PARP1 | PML | RB1 1116
7. positive regulation of apoptotic process Breast Neoplasms Inferred via 105 chemicals: 2-chloro-5-nitrobenzanilide | 3,3'-diindolylmethane | 7-hydroxystaurosporine | Acrylamide | Aminoglutethimide | Apigenin | Arsenic | Arsenic Trioxide | Ascorbic Acid | Aspirin | Atrazine | Benzo(a)pyrene | Biological Products | bisphenol A | Bortezomib | Cadmium | Calcitriol | Carbamazepine | Chloroquine | Chlorpyrifos | Chromium | Cisplatin | Cobalt | Copper | Curcumin | Cyclophosphamide | Cyclosporine | Cytarabine | Decitabine | Deferoxamine | Deoxyglucose | Dexamethasone | diallyl trisulfide | Dichlorodiphenyl Dichloroethylene | Dicumarol | Dietary Fats | Diethylhexyl Phthalate | Diethylnitrosamine | Dinoprostone | Disulfiram | Docetaxel | Doxorubicin | epigallocatechin gallate | Equol | Estradiol | estradiol 3-benzoate | Estrogens | Ethanol | Etoposide | Fluorouracil | Formaldehyde | Fulvestrant | Gefitinib | gemcitabine | Genistein | gingerol | Indomethacin | Lapatinib | mancozeb | Manganese | mangostin | Melphalan | Methotrexate | methyleugenol | Mitomycin | mono-(2-ethylhexyl)phthalate | Nickel | Niclosamide | Nicotine | Nitric Oxide | ochratoxin A | Organoselenium Compounds | Oxygen | Paclitaxel | Parathion | perfluorooctane sulfonic acid | perfluorooctanoic acid | Plant Extracts | Plant Preparations | Progesterone | pterostilbene | pyrrolidine dithiocarbamic acid | Quercetin | Quinine | Resveratrol | Rosiglitazone | salinomycin | selenomethylselenocysteine | Sorafenib | Sulindac | Tamoxifen | Tetrachlorodibenzodioxin | Tobacco Smoke Pollution | Tretinoin | valspodar | Vehicle Emissions | veliparib | Verapamil | Vincristine | Vitamin E | Vorinostat | Water Pollutants, Chemical | Wortmannin | Zinc | Zoledronic Acid Inferred via 59 genes: ABL1 | ADAM10 | AKT1 | ATM | BARD1 | BAX | BMP2 | BMP4 | C1QBP | CASP8 | CDKN2A | CTNNB1 | CYP1B1 | DDIT3 | E2F1 | ESR2 | FOXA1 | GPER1 | HIF1A | HMOX1 | HRG | IDO1 | IFNG | IL1B | IL24 | IL6 | JUN | LPAR1 | MAP3K1 | MIR200B | MIR221 | MIR29A | MMP2 | MMP9 | NCOA1 | NOS2 | NOS3 | NOTCH1 | NOTCH2 | PLA2G4A | PTEN | PTGS2 | RARB | RELA | RPS6 | SFRP1 | SFRP2 | SIRT1 | SRC | TGM2 | TNF | TNFSF10 | TOP2A | TP53 | TP73 | TRP53 | UBD | WNT10B | WT1 1060
8. apoptotic process Exanthema Inferred via 104 chemicals: Acetaminophen | Alendronate | Allopurinol | Alprostadil | Amifostine | Amiodarone | Amlodipine | Amoxicillin | Angiotensin-Converting Enzyme Inhibitors | Arsenic Trioxide | Aspirin | Atenolol | Azithromycin | Budesonide | Celecoxib | Cephalothin | Chlorambucil | Chloramphenicol | Chlorpromazine | Cimetidine | Ciprofloxacin | Cisplatin | Clarithromycin | Clofibrate | Clozapine | Cocaine | Cyclophosphamide | Cyclosporine | Cytarabine | Dexamethasone | Diatrizoate | Diazoxide | Diclofenac | Diltiazem | Diphenhydramine | Disulfiram | Doxycycline | Enalapril | Erlotinib Hydrochloride | Everolimus | Formaldehyde | gemcitabine | Gentamicins | Glutathione | Glyburide | Gold | Hydroxychloroquine | Imatinib Mesylate | Imipramine | Indomethacin | Isoniazid | Isotretinoin | Leucovorin | Levamisole | Lisinopril | Lithium | Lovastatin | Maprotiline | Medroxyprogesterone Acetate | Mercury | Methimazole | Methotrexate | Metoprolol | Minocycline | Mitotane | Morphine | Mycophenolic Acid | Naltrexone | Naproxen | Nelfinavir | Niacin | Nicotine | Nifedipine | Ofloxacin | Ozone | Paclitaxel | palbociclib | Particulate Matter | Pemetrexed | Penicillamine | Pentoxifylline | Pergolide | Phenobarbital | Phenytoin | Prednisolone | Propofol | Propranolol | Propylthiouracil | Quinidine | Roxithromycin | Sirolimus | Sorafenib | Sulfasalazine | Sulindac | temsirolimus | Thalidomide | Thymidine | Ticlopidine | Tramadol | Valproic Acid | Vancomycin | Vehicle Emissions | Vincristine | Zidovudine   1495
9. apoptotic process Pruritus Inferred via 98 chemicals: Acetaminophen | Acitretin | Amiodarone | Amitriptyline | Amlodipine | Angiotensin-Converting Enzyme Inhibitors | Arsenic Trioxide | Aspirin | Atorvastatin | Azithromycin | Betamethasone | Bupivacaine | Capsaicin | Carboplatin | Carvedilol | Celecoxib | Cephalothin | Chloroquine | Chlorpheniramine | Chlorpromazine | Cimetidine | Ciprofloxacin | Danazol | Dexamethasone | Diatrizoate | Diatrizoate Meglumine | Diazepam | Diclofenac | Dinoprostone | Diphenhydramine | Disulfiram | Doxorubicin | Doxycycline | Enalapril | Epinephrine | Estradiol | Ethinyl Estradiol | Etoposide | Fosinopril | Gentamicins | ginsenoside Re | ginsenoside Rh1 | Glyburide | Histamine | Hydroxyurea | Indapamide | Iohexol | Isotretinoin | Ketamine | Melatonin | Memantine | Mesalamine | Metformin | Methimazole | Methotrexate | Methylprednisolone | Metoprolol | Minoxidil | MK-886 | Morphine | Mustard Gas | Mycophenolic Acid | Naloxone | Naltrexone | Niacin | Nicotine | Norethindrone | Olanzapine | Omeprazole | Paclitaxel | Paroxetine | Penicillamine | Phenytoin | Plant Extracts | Prednisolone | Procaine | Propofol | Rifampin | rofecoxib | Ropivacaine | Simvastatin | Sodium Benzoate | Sulfasalazine | Sulindac | Tacrolimus | Terfenadine | Thalidomide | Ticlopidine | Tramadol | Tretinoin | Troglitazone | Ursodeoxycholic Acid | Valproic Acid | Vancomycin | Verapamil | Vitamin D | Warfarin | zileuton   1379
10. cell proliferation Stevens-Johnson Syndrome Inferred via 97 chemicals: Acetaminophen | Albendazole | Alendronate | Allopurinol | Alprazolam | Amifostine | Amiodarone | Atorvastatin | Azithromycin | Bortezomib | Bumetanide | Carvedilol | Celecoxib | cerivastatin | Cilostazol | Ciprofloxacin | Citalopram | Cladribine | Clofarabine | Clozapine | Cyclophosphamide | Cyclosporine | Dactinomycin | Diclofenac | Diltiazem | Docetaxel | Doxorubicin | efavirenz | Enalapril | Erlotinib Hydrochloride | Etoposide | Fluoxetine | Flurbiprofen | Fluvastatin | Furosemide | Gefitinib | Griseofulvin | Hydroxychloroquine | Ibuprofen | Ifosfamide | Indapamide | Indomethacin | Isotretinoin | Itraconazole | Ivermectin | Lansoprazole | Leflunomide | Letrozole | Losartan | Lovastatin | Meloxicam | Mesna | Methotrexate | Minocycline | N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine | Nevirapine | Nifedipine | Nitric Oxide | Ofloxacin | Omeprazole | Paclitaxel | Paroxetine | Pemetrexed | Penicillamine | Phenobarbital | Phenytoin | Prednisolone | Pregabalin | Propranolol | Propylthiouracil | Pyrimethamine | Ramipril | Ranitidine | Ribavirin | Rifampin | Ritonavir | rofecoxib | Rosiglitazone | Saquinavir | Simvastatin | Sorafenib | Spironolactone | Sulfasalazine | Sulindac | Tacrolimus | Tadalafil | Tamoxifen | Temozolomide | temsirolimus | teriflunomide | Thalidomide | Tigecycline | Topiramate | Trichloroethylene | Valproic Acid | Vemurafenib | Verapamil Inferred via 3 genes: CTNNB1 | CUL1 | MIF 648
11. apoptotic process Drug Eruptions Inferred via 97 chemicals: Acetaminophen | Acetazolamide | Acetylcysteine | Allopurinol | Amiloride | Amiodarone | Angiotensin-Converting Enzyme Inhibitors | Aspirin | Atenolol | Azithromycin | Betamethasone | Bezafibrate | Bromocriptine | Budesonide | Caffeine | Calcitriol | Capsaicin | Carboplatin | Carvedilol | Cefotaxime | Celecoxib | Cephalothin | Chlorambucil | Chlorpheniramine | Cimetidine | Ciprofloxacin | Clarithromycin | Clozapine | Cocaine | Diclofenac | Diphenhydramine | Docetaxel | Doxycycline | Enalapril | Gangliosides | Gefitinib | Glucocorticoids | hydrocortisone-17-butyrate | Hydroxyurea | Ibuprofen | Indinavir | Indomethacin | Isoniazid | Ketoconazole | Leucovorin | Levamisole | Lidocaine | liposomal doxorubicin | Mannitol | Meloxicam | Mepivacaine | Mercaptopurine | Mesalamine | Methimazole | Methotrexate | Minocycline | Mitoxantrone | Naltrexone | Naproxen | Nelfinavir | nickel sulfate | Nifedipine | Niflumic Acid | nimesulide | Ofloxacin | Omeprazole | Paclitaxel | Penicillamine | Phenobarbital | Phenytoin | pimecrolimus | Piroxicam | Plant Extracts | Potassium Dichromate | Pravastatin | Prazosin | Propranolol | Pyrazinamide | Quinidine | Ramipril | Rifampin | rofecoxib | Roxithromycin | Sirolimus | Sorafenib | Sulfasalazine | Tamoxifen | Thalidomide | Thiopental | Ticlopidine | Tretinoin | Valproic Acid | Vancomycin | Vitamin A | Vitamin E | Vitamin K 1 | Warfarin   1172
12. response to oxidative stress Breast Neoplasms Inferred via 95 chemicals: 2-chloro-5-nitrobenzanilide | 3,3',4,5'-tetrahydroxystilbene | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | Air Pollutants | allyl sulfide | Amifostine | Apigenin | Arsenic | Arsenic Trioxide | Ascorbic Acid | Aspirin | Benzo(a)pyrene | beta-Naphthoflavone | Biological Products | bisphenol A | Bortezomib | Butylated Hydroxyanisole | Cacodylic Acid | Cadmium | Caffeine | Calcitriol | Capsaicin | Carboplatin | Celecoxib | Chloroquine | Cisplatin | Copper | Curcumin | Cyclophosphamide | Cyclosporine | Dapsone | DDT | Deferoxamine | Dexamethasone | Dichlorodiphenyl Dichloroethylene | Dicumarol | Dietary Fats | Diethylnitrosamine | Diltiazem | Dinoprostone | Disulfiram | Docetaxel | Doxorubicin | Estradiol | Estrogens | Ethanol | Fadrozole | Fenretinide | Fluorouracil | Genistein | Hexachlorocyclohexane | Hydrocortisone | Indomethacin | Malathion | Manganese | Masoprocol | Methylcholanthrene | Mitomycin | Nelfinavir | Niacin | Niclosamide | Nicotine | nimesulide | Nitric Oxide | Nitrofurazone | Nitrogen Dioxide | Nitroglycerin | ochratoxin A | Oxygen | Pemetrexed | Plant Extracts | Plant Oils | Plant Preparations | Progesterone | Quercetin | Razoxane | Reserpine | Resveratrol | Riboflavin | Rosiglitazone | Selenium | Smoke | Sorafenib | Sulfasalazine | Sulindac | Tamoxifen | Testosterone | Tetrachlorodibenzodioxin | Tobacco Smoke Pollution | Tretinoin | Vehicle Emissions | Vitamin E | Vorinostat | Wortmannin | Zinc Inferred via 25 genes: ABCC1 | ABL1 | ADAR | AKT1 | BCL2 | CAT | DDIT3 | EGFR | FBL | GPX1 | GPX2 | GPX4 | HMOX1 | MMP14 | MMP2 | MMP9 | MT3 | NQO1 | PTGS1 | PTGS2 | SIRT1 | SOD2 | STC2 | TP53 | TRP53 890
13. regulation of mitochondrial membrane potential Breast Neoplasms Inferred via 92 chemicals: 2-chloro-5-nitrobenzanilide | 7-hydroxystaurosporine | alvocidib | Apigenin | Arsenic | Arsenic Trioxide | Ascorbic Acid | Aspirin | Benzo(a)pyrene | bicalutamide | bisphenol A | Bortezomib | Cadmium | Caffeine | Calcitriol | Capsaicin | Celecoxib | Chlorpyrifos | Ciclopirox | Cisplatin | Cobalt | Copper | Curcumin | Cyclosporine | Dasatinib | Decitabine | Deferoxamine | deguelin | Dexamethasone | diallyl trisulfide | Dicumarol | Dietary Fats | Diethylhexyl Phthalate | Dinoprostone | Disulfiram | Docetaxel | Doxorubicin | epicatechin gallate | epigallocatechin gallate | Epirubicin | Estradiol | Ethanol | Etoposide | Fenretinide | Fluorouracil | Fulvestrant | gemcitabine | gingerol | Imatinib Mesylate | indole-3-carbinol | Indomethacin | kaempferol | Manganese | mangostin | Masoprocol | Mitomycin | Mitoxantrone | Nickel | Nicotine | Nitric Oxide | ochratoxin A | Oxygen | Paclitaxel | parthenolide | perfluorooctane sulfonic acid | Plant Extracts | Plant Preparations | platycodin D | pterostilbene | Quercetin | Resveratrol | Rosiglitazone | salicylaldehyde isonicotinoyl hydrazone | salinomycin | Selenium | Sorafenib | Sulfasalazine | Sulindac | Tamoxifen | Tetrachlorodibenzodioxin | Tobacco Smoke Pollution | Tretinoin | Vehicle Emissions | Verapamil | Vincristine | Vitamin E | Vorinostat | Water Pollutants, Chemical | Wortmannin | Zidovudine | Zinc | Zoledronic Acid Inferred via 4 genes: BAX | BCL2 | CLIC1 | SOD2 882
14. cell proliferation Pruritus Inferred via 92 chemicals: 4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol | Acetaminophen | Acitretin | Adrenal Cortex Hormones | Air Pollutants, Occupational | Albendazole | Amiodarone | Amitriptyline | Amlodipine | Arsenic Trioxide | Aspirin | Atorvastatin | azelastine | Azithromycin | benoxaprofen | Capsaicin | Carboplatin | Carvedilol | Celecoxib | Chloroquine | Chlorpromazine | Cimetidine | Cinacalcet | Ciprofloxacin | Cyproheptadine | Dexamethasone | Diatrizoate | Diazepam | Diclofenac | Dinitrofluorobenzene | Dinoprostone | Diphenhydramine | Disulfiram | Doxorubicin | Enalapril | Epinephrine | Estradiol | Ethinyl Estradiol | Etoposide | Gentamicins | ginsenoside Re | ginsenoside Rh1 | Histamine | Hydroxyurea | Indapamide | Isotretinoin | Ivermectin | Ketamine | Melatonin | Mesna | Metformin | Methimazole | Methotrexate | Methoxychlor | Minoxidil | MK-886 | Morphine | Mustard Gas | Mycophenolic Acid | Naloxone | Naltrexone | Nicotine | Norethindrone | Olanzapine | Omeprazole | Paclitaxel | Paroxetine | Penicillamine | Phenytoin | Plant Extracts | Prednisolone | Pregabalin | Rifampin | rofecoxib | Ropivacaine | Serotonin | Simvastatin | Sodium Benzoate | Sulfasalazine | Sulindac | Tacrolimus | Terfenadine | Tetracycline | Thalidomide | Tretinoin | Trichloroethylene | Troglitazone | Ursodeoxycholic Acid | Valproic Acid | Verapamil | Warfarin | zileuton   942
15. cell proliferation Exanthema Inferred via 91 chemicals: Acetaminophen | Adrenal Cortex Hormones | Alendronate | Allopurinol | Alprostadil | Amifostine | Amiodarone | Amlodipine | Arsenic Trioxide | Aspirin | Atenolol | Azithromycin | Budesonide | Celecoxib | Chlorpromazine | Cimetidine | Ciprofloxacin | Cisplatin | Clofibrate | Clozapine | Cocaine | Contrast Media | Cyclophosphamide | Cyclosporine | Cytarabine | Dexamethasone | Diatrizoate | Diazoxide | Diclofenac | Diltiazem | Diphenhydramine | Disulfiram | efavirenz | Enalapril | Erlotinib Hydrochloride | Everolimus | Flurbiprofen | Formaldehyde | gemcitabine | Gentamicins | Glutathione | Gold | Hydroxychloroquine | Imatinib Mesylate | Imipramine | Indomethacin | Isotretinoin | Levamisole | Lithium | Lovastatin | Maprotiline | Medroxyprogesterone Acetate | Mercury | Mesna | Methimazole | Methotrexate | Minocycline | Mitotane | Morphine | Mycophenolic Acid | Naltrexone | Nelfinavir | Nevirapine | Nicotine | Nifedipine | Ofloxacin | Ozone | Paclitaxel | palbociclib | Particulate Matter | Pemetrexed | Penicillamine | Pentoxifylline | Pergolide | Phenobarbital | Phenylbutazone | Phenytoin | Prednisolone | Propranolol | Propylthiouracil | Quinidine | Sirolimus | Sorafenib | Sulfasalazine | Sulindac | temsirolimus | Thalidomide | Thymidine | Valproic Acid | Vehicle Emissions | Vincristine   950
16. apoptotic process Angioedema Inferred via 91 chemicals: 4-phenylenediamine | Acetaminophen | Acetylcysteine | Albuterol | Alendronate | Alprazolam | Amiodarone | Amlodipine | Amoxicillin | Angiotensin-Converting Enzyme Inhibitors | Apomorphine | Aspirin | Astemizole | benazepril | Bezafibrate | Budesonide | Calcitriol | candesartan | Celecoxib | Chloramphenicol | Chloroquine | Cilazapril | Cimetidine | Ciprofloxacin | Clozapine | Cocaine | Danazol | Desipramine | Diclofenac | Diltiazem | Dinoprost | Diphenhydramine | Dipyridamole | Doxazosin | Doxorubicin | Enalapril | Epinephrine | Epirubicin | Estramustine | Estrogens | Ethinyl Estradiol | Everolimus | Fluorouracil | Fluoxetine | Fosinopril | Glucocorticoids | Histamine | Hydrocortisone | Ibuprofen | Indomethacin | Irbesartan | Isotretinoin | Isradipine | Ketoconazole | Lidocaine | Lisinopril | Losartan | Lovastatin | Mepivacaine | Mesalamine | Methotrexate | Methylprednisolone | Metoprolol | montelukast | Naproxen | Nifedipine | nimesulide | Nitroglycerin | Omeprazole | Oxygen | Paroxetine | Perindopril | Phenytoin | Piroxicam | Prednisolone | Progesterone | Propranolol | Ramipril | rofecoxib | Salmeterol Xinafoate | Sirolimus | Sulfasalazine | Tacrolimus | Telmisartan | Terfenadine | Thiopental | Ticlopidine | Tramadol | Trifluoperazine | Valsartan | Verapamil   1148
17. cell cycle Breast Neoplasms Inferred via 89 chemicals: 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin | 2-Methoxyestradiol | 3,3'-diindolylmethane | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | 7-hydroxystaurosporine | Alitretinoin | alvocidib | Amifostine | Apigenin | Arsenic Trioxide | Ascorbic Acid | Aspirin | Benzo(a)pyrene | bicalutamide | bisphenol A | Bortezomib | Cadmium | Caffeine | Calcitriol | Capsaicin | Carboplatin | Carmustine | Celecoxib | Chloroquine | Cisplatin | Curcumin | Cyclophosphamide | Cyclosporine | Cytarabine | Dasatinib | Decitabine | Deferoxamine | Dexamethasone | Diethylstilbestrol | Dinoprostone | Docetaxel | Doxorubicin | Estradiol | Estrogens | Etoposide | Fluorouracil | Gefitinib | gemcitabine | Genistein | Imatinib Mesylate | indole-3-carbinol | Indomethacin | Lapatinib | Letrozole | Masoprocol | Melphalan | Methotrexate | Mitomycin | Nelfinavir | Niacin | Nicotine | nimesulide | Nitric Oxide | Orlistat | Paclitaxel | Pemetrexed | Pesticides | pirarubicin | Plant Extracts | Prednisolone | pyrrolidine dithiocarbamic acid | Quinine | Raloxifene Hydrochloride | Razoxane | Resveratrol | Retinoids | Riboflavin | Rosiglitazone | RTKI cpd | seocalcitol | Sorafenib | Sulindac | Tamoxifen | temsirolimus | Tetrachlorodibenzodioxin | tipifarnib | Tobacco Smoke Pollution | Toremifene | Tretinoin | Vinblastine | Vincristine | Vitamin E | Vorinostat | Zidovudine Inferred via 35 genes: AHR | ATM | AURKA | BIRC5 | BRCA1 | BRCA2 | CCND1 | CCNE1 | CDKN1B | CDKN2A | CHEK1 | CHEK2 | DDIT3 | E2F1 | EP300 | FOXM1 | GNAI2 | GPER1 | H2AFX | KLK10 | KRT18 | LLGL2 | MKI67 | PIM1 | PIN1 | PPM1D | PRC1 | RB1 | RB1CC1 | RGS2 | SRC | TP53 | TP53BP2 | TRP53 | UBE2C 976
18. cell proliferation Drug Eruptions Inferred via 89 chemicals: 3,3',4,5'-tetrahydroxystilbene | Acetaminophen | Acetylcysteine | Adrenal Cortex Hormones | Allopurinol | Amiloride | Amiodarone | Aspirin | Atenolol | Azithromycin | Budesonide | Caffeine | Calcitriol | Capsaicin | Carboplatin | Carvedilol | Celecoxib | Cimetidine | Cinacalcet | Ciprofloxacin | Clozapine | Cocaine | Contrast Media | Diclofenac | Dinitrochlorobenzene | Dinitrofluorobenzene | Diphenhydramine | Docetaxel | efavirenz | Enalapril | Eugenol | Fluocinolone Acetonide | Flurbiprofen | Furosemide | Gefitinib | Glucocorticoids | hydrocortisone-17-butyrate | Hydroxyurea | Ibuprofen | Indomethacin | Itraconazole | Ketoconazole | Levamisole | Lidocaine | liposomal doxorubicin | Mannitol | Meloxicam | Mercaptopurine | Methimazole | Methotrexate | Minocycline | Mitoxantrone | Naltrexone | Nelfinavir | Nevirapine | nickel sulfate | Nifedipine | Niflumic Acid | nimesulide | Ofloxacin | Omeprazole | Oxprenolol | Paclitaxel | Penicillamine | Phenobarbital | Phenytoin | pimecrolimus | Plant Extracts | Potassium Dichromate | Prazosin | Propranolol | Pyrazinamide | Quinidine | Ramipril | Rifampin | rofecoxib | Sirolimus | Sorafenib | Sulfasalazine | Tamoxifen | Thalidomide | Thiopental | Tretinoin | Trichloroethylene | Valproic Acid | Vitamin A | Vitamin E | Vitamin K 1 | Warfarin Inferred via 2 genes: CYP1A1 | IL18 832
19. cell death Stevens-Johnson Syndrome Inferred via 88 chemicals: Acetaminophen | Albendazole | Allopurinol | Amifostine | Amiodarone | Aprepitant | Atorvastatin | Atovaquone | Bortezomib | Bupropion | Carbamazepine | Carvedilol | Ceftriaxone | Celecoxib | Chlorambucil | Cilostazol | Cladribine | Clofarabine | Clozapine | Cyclosporine | Dactinomycin | Diclofenac | Diltiazem | Docetaxel | Doxorubicin | Doxycycline | Enalapril | Erlotinib Hydrochloride | Ethosuximide | Etoposide | fludarabine | Fluoxetine | Fluvastatin | Furosemide | Gefitinib | Griseofulvin | Hydrochlorothiazide | Ibuprofen | Indapamide | Indomethacin | Itraconazole | Ivermectin | Ketoprofen | Leflunomide | Letrozole | Losartan | Lovastatin | Mefloquine | Meloxicam | Methotrexate | Minocycline | Nifedipine | Nitric Oxide | Ofloxacin | Omeprazole | Paclitaxel | Penicillamine | Pentamidine | Phenobarbital | Phenytoin | Piroxicam | Propranolol | Pyrimethamine | Quinine | Ribavirin | Rifampin | Ritonavir | Rivastigmine | rofecoxib | Rosiglitazone | Simvastatin | Sorafenib | Sulindac | Tacrolimus | Tamoxifen | Temozolomide | temsirolimus | teriflunomide | Thalidomide | Thiabendazole | Tolmetin | Topiramate | Tramadol | Trichloroethylene | Valproic Acid | Vemurafenib | Verapamil | Zidovudine Inferred via 1 gene: PTGER3 278
20. reactive oxygen species biosynthetic process Breast Neoplasms Inferred via 84 chemicals: 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine | 3,3',4,5'-tetrahydroxystilbene | 4-nonylphenol | Acrylamide | Air Pollutants | Apigenin | Arsenic | Arsenic Trioxide | Ascorbic Acid | Atrazine | Benzene | Benzo(a)pyrene | bisphenol A | Butylated Hydroxyanisole | Cacodylic Acid | Cadmium | Carmustine | Catechin | Chalcones | Chloroquine | Chlorpyrifos | Cisplatin | Cobalt | Copper | Curcumin | Cyclosporine | Decitabine | Deferoxamine | Dexamethasone | diallyl trisulfide | Dichlorodiphenyl Dichloroethylene | Dietary Fats | Diethylhexyl Phthalate | Disulfiram | Docetaxel | Doxorubicin | epicatechin gallate | epigallocatechin gallate | Epirubicin | Estradiol | Ethanol | Etoposide | Formaldehyde | Fulvestrant | Gefitinib | gemcitabine | Genistein | gingerol | Grape Seed Proanthocyanidins | Imatinib Mesylate | indole-3-carbinol | Indomethacin | isoliquiritigenin | kaempferol | mangostin | Masoprocol | mono-(2-ethylhexyl)phthalate | Nickel | Nicotine | nimesulide | Nitric Oxide | ochratoxin A | Oleic Acid | Oxygen | parthenolide | perfluorooctane sulfonic acid | Plant Extracts | Plant Preparations | propylene dichloride | Quercetin | Resveratrol | Smoke | Styrene | Sulfasalazine | Tamoxifen | tanshinone | Tetrachlorodibenzodioxin | Tretinoin | Vehicle Emissions | Verapamil | Vitamin E | Water Pollutants, Chemical | Wortmannin | Zidovudine   734
21. mitotic cell cycle arrest Breast Neoplasms Inferred via 82 chemicals: 2,3-bis(3'-hydroxybenzyl)butyrolactone | 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine | 2-chloro-5-nitrobenzanilide | 3,3'-diindolylmethane | 4-nonylphenol | Acrylamide | ado-trastuzumab emtansine | Air Pollutants | Apigenin | Arsenic | Arsenic Trioxide | Ascorbic Acid | Atrazine | aurapten | Benzo(a)pyrene | beta-Naphthoflavone | betulinic acid | bisphenol A | Butylated Hydroxyanisole | Cadmium | Calcitriol | Carmustine | Chalcones | Chlorpyrifos | Cisplatin | Curcumin | Cytarabine | Dasatinib | Decitabine | Deoxyglucose | diallyl trisulfide | Disulfiram | Docetaxel | Doxorubicin | epigallocatechin gallate | Estrogens | Ethanol | Etoposide | Fluorouracil | Folic Acid | Formaldehyde | Fulvestrant | Gefitinib | gemcitabine | Hexachlorobenzene | Imatinib Mesylate | isoliquiritigenin | kaempferol | liposomal doxorubicin | Methotrexate | Methylcholanthrene | Methylnitrosourea | Niclosamide | Nicotine | Nitrogen Dioxide | ochratoxin A | Organoselenium Compounds | Oxygen | Paclitaxel | palbociclib | perfluorooctane sulfonic acid | perfluorooctanoic acid | Pesticides | Plant Extracts | Plant Preparations | pterostilbene | Pyrimidines | pyrrolidine dithiocarbamic acid | Quercetin | Resveratrol | Rosiglitazone | selenomethylselenocysteine | Smoke | Sorafenib | tangeretin | temsirolimus | Tetrachlorodibenzodioxin | Tretinoin | Vincristine | Vorinostat | xanthohumol | Zinc Inferred via 3 genes: CDKN1B | TP53 | TRP53 610
22. cell death Drug Eruptions Inferred via 82 chemicals: Acetaminophen | Acetylcysteine | Allopurinol | Amiodarone | Aspirin | Azathioprine | Betamethasone Valerate | Bezafibrate | Bromocriptine | Bupropion | Caffeine | Calcitriol | Capsaicin | Carbamazepine | Carboplatin | Carvedilol | Ceftriaxone | Celecoxib | Chlorambucil | Cimetidine | Clozapine | Cocaine | Dapsone | Diclofenac | Dinitrochlorobenzene | Docetaxel | Doxycycline | Edetic Acid | Enalapril | Eugenol | Furosemide | Gangliosides | Gefitinib | Glucocorticoids | Hydroxyurea | Ibuprofen | Imipenem | Indomethacin | Isoniazid | Itraconazole | Ketoconazole | Ketoprofen | Lidocaine | liposomal doxorubicin | Mefloquine | Meloxicam | Mercaptopurine | Methimazole | Methotrexate | Minocycline | Mitoxantrone | Naltrexone | Nelfinavir | Nifedipine | nimesulide | Ofloxacin | Omeprazole | Paclitaxel | Penicillamine | Phenobarbital | Phenytoin | Piroxicam | Plant Extracts | Potassium Dichromate | Primaquine | Propranolol | Quinidine | Quinine | Rifampin | rofecoxib | Sirolimus | Sorafenib | Tamoxifen | Thalidomide | Thiopental | Tolmetin | Tretinoin | Trichloroethylene | Valproic Acid | Vitamin A | Vitamin E | Warfarin   389
23. cell death Exanthema Inferred via 82 chemicals: Acetaminophen | Allopurinol | Amifostine | Amiodarone | Amlodipine | Arsenic Trioxide | Aspirin | Azathioprine | Bupropion | Carbamazepine | Ceftriaxone | Celecoxib | Chlorambucil | Chloramphenicol | Chlorpromazine | Cimetidine | Cisplatin | Clonidine | Clozapine | Cocaine | Cyclosporine | Cytarabine | Dapsone | Deferasirox | Dexamethasone | Diazoxide | Diclofenac | Diltiazem | Disulfiram | Doxycycline | Dronedarone | Enalapril | Erlotinib Hydrochloride | Everolimus | Formaldehyde | gemcitabine | Gentamicins | Glutathione | Glyburide | Imatinib Mesylate | Imipramine | Indomethacin | Isoniazid | Lithium | Lovastatin | Maprotiline | Mercury | Methimazole | Methotrexate | Methyldopa | Metoprolol | Minocycline | Mitotane | Morphine | Mycophenolic Acid | Naltrexone | Nelfinavir | Nicotine | Nifedipine | Ofloxacin | Ozone | Paclitaxel | palbociclib | Particulate Matter | Penicillamine | Pentamidine | Pentoxifylline | Pergolide | Phenobarbital | Phenytoin | Propranolol | Quinidine | Sirolimus | Sorafenib | Sulindac | temsirolimus | Thalidomide | Tramadol | Valproic Acid | Vehicle Emissions | Vincristine | Zidovudine   465
24. apoptotic process Urticaria Inferred via 81 chemicals: Acetaminophen | Acetazolamide | Allopurinol | Amiloride | Amoxicillin | Angiotensin-Converting Enzyme Inhibitors | Aspirin | Astemizole | Azithromycin | Caffeine | Cefotaxime | Celecoxib | chloroprocaine | Chlorpheniramine | Cimetidine | cinnamic aldehyde | Ciprofloxacin | Cytarabine | Dexamethasone | Diatrizoate | Diatrizoate Meglumine | Diclofenac | Diltiazem | Dimethyl Sulfoxide | Diphenhydramine | Doxorubicin | Epinephrine | Etoposide | Fluoxetine | Formaldehyde | Gangliosides | Histamine | Hydrocortisone | Hydroxychloroquine | Ibuprofen | Indomethacin | Iohexol | ioversol | Isosorbide Dinitrate | Isotretinoin | Ketoconazole | Lansoprazole | Lidocaine | Losartan | Lovastatin | Mannitol | Meloxicam | Mepivacaine | Methimazole | Methylprednisolone | Minocycline | montelukast | Naproxen | Nifedipine | Niflumic Acid | nimesulide | Ofloxacin | Omeprazole | Paroxetine | Pemetrexed | Penicillamine | Piroxicam | Plant Extracts | Propylthiouracil | Quinidine | Ramipril | Ranitidine | Rifampin | Roxithromycin | Salicylic Acid | Salmeterol Xinafoate | Sodium Benzoate | Sulfasalazine | Terbutaline | Terfenadine | Thalidomide | Thiopental | Ticlopidine | Vancomycin | Vitamin A | Vitamin E Inferred via 2 genes: IL1B | TNF 799
25. apoptotic DNA fragmentation Breast Neoplasms Inferred via 81 chemicals: 2-chloro-5-nitrobenzanilide | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | 7-hydroxystaurosporine | 9,10-Dimethyl-1,2-benzanthracene | alvocidib | Amifostine | Apigenin | Arsenic Trioxide | Ascorbic Acid | Aspirin | Bortezomib | Cadmium | Caffeine | Calcitriol | Capsaicin | Carboplatin | Celecoxib | Chloroquine | Cisplatin | Curcumin | Cyclophosphamide | Cyclosporine | Cytarabine | Decitabine | Deoxyglucose | Dexamethasone | Dinoprostone | Disulfiram | Docetaxel | Doxorubicin | Doxycycline | Epirubicin | Estradiol | Ethanol | Etoposide | Fenretinide | Fluorouracil | gemcitabine | Genistein | Hydrocortisone | Indomethacin | Lignans | Malathion | Masoprocol | Medroxyprogesterone Acetate | Methylcholanthrene | Mitomycin | Mitoxantrone | Nickel | Nicotine | nimesulide | Nitric Oxide | Nitrofurazone | ochratoxin A | Oxygen | Paclitaxel | Pamidronate | Plant Extracts | Prednisolone | pyrrolidine dithiocarbamic acid | Quercetin | Razoxane | Resveratrol | Riboflavin | Rosiglitazone | seocalcitol | Smoke | Sulfasalazine | Sulindac | tangeretin | Testosterone | Tetrachlorodibenzodioxin | Tretinoin | Vehicle Emissions | Verapamil | Vincristine | Vitamin E | Vorinostat | Wortmannin | Zinc | Zoledronic Acid   743
26. cell proliferation Skin Neoplasms Inferred via 80 chemicals: 1,2,5,6-dibenzanthracene | 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine | 3-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole | 3-amino-1-methyl-5H-pyrido(4,3-b)indole | 8-bromocyclic GMP | 9,10-Dimethyl-1,2-benzanthracene | Acetylcysteine | Acitretin | allyl sulfide | Apigenin | argemone oil | Arsenic | arsenite | Azacitidine | Benzo(a)pyrene | Butyric Acid | Cacodylic Acid | Caffeine | Calcitriol | Capsaicin | Carmustine | corosolic acid | cumene hydroperoxide | Curcumin | deguelin | Dichloroacetic Acid | Dietary Fats | Docetaxel | Doxorubicin | Dust | Ellagic Acid | epigallocatechin gallate | Eugenol | Fenretinide | Gefitinib | Geraniin | gingerol | Glucose | glyphosate | GW0742 | Hydrogen Peroxide | Hydroxyurea | Iron | Isotretinoin | Lycopene | mancozeb | maslinic acid | Masoprocol | Melphalan | Methotrexate | Methylnitrosourea | monomethylarsonous acid | Niacinamide | Nicotine | nimesulide | Okadaic Acid | Oleanolic Acid | Paclitaxel | Plant Extracts | Polylactic Acid-Polyglycolic Acid Copolymer | pterostilbene | Quercetin | Resveratrol | sanguinarine | Silymarin | Sirolimus | sodium arsenite | Tacrolimus | tert-Butylhydroperoxide | Tetrachlorodibenzodioxin | Tetradecanoylphorbol Acetate | Thapsigargin | tipifarnib | Tobacco Smoke Pollution | Tretinoin | Troglitazone | Tunicamycin | Urethane | ursolic acid | Vincristine Inferred via 11 genes: AKT1 | ERBB4 | ERCC2 | GLI2 | HRAS | IGF1 | IL1A | PPARD | TGFB1 | TP53 | TYR 1019
27. lipid catabolic process Breast Neoplasms Inferred via 80 chemicals: 2-chloro-5-nitrobenzanilide | 3,3',4,5'-tetrahydroxystilbene | 4-nonylphenol | 9,10-Dimethyl-1,2-benzanthracene | Acrylamide | Apigenin | Arsenic | Arsenic Trioxide | Ascorbic Acid | Aspirin | Atrazine | Benzo(a)pyrene | bisphenol A | Cadmium | Caffeine | Catechin | Chloroquine | Chlorpyrifos | Cisplatin | Cobalt | Copper | Curcumin | Cyclophosphamide | Cyclosporine | Dexamethasone | Dichlorodiphenyl Dichloroethylene | Dietary Fats | Diethylhexyl Phthalate | Diethylnitrosamine | Dinoprostone | Doxorubicin | Doxycycline | epigallocatechin gallate | Ethanol | Famotidine | Fluorouracil | Formaldehyde | Genistein | gingerol | Grape Seed Proanthocyanidins | Hexachlorobenzene | Hydrocortisone | Imatinib Mesylate | indole-3-carbinol | Indomethacin | kaempferol | Letrozole | Malathion | Manganese | Mesna | Methotrexate | mono-(2-ethylhexyl)phthalate | Nelfinavir | Niacin | Nickel | Nicotine | ochratoxin A | Oleic Acid | Olive Oil | Orlistat | Oxygen | perfluorooctane sulfonic acid | perfluorooctanoic acid | Plant Extracts | Plant Oils | Plant Preparations | Progesterone | Quercetin | Ranitidine | Resveratrol | Rosiglitazone | Selenium | Styrene | Sulfasalazine | tangeretin | Testosterone | Tobacco Smoke Pollution | Vitamin E | Water Pollutants, Chemical | Zinc Inferred via 1 gene: PLA2G4A 653
28. cell death Pruritus Inferred via 79 chemicals: Acetaminophen | Albendazole | Amiodarone | Amitriptyline | Amlodipine | Arsenic Trioxide | Aspirin | Atorvastatin | Azathioprine | Betamethasone Valerate | Bupivacaine | Bupropion | Capsaicin | Carbamazepine | Carboplatin | Carvedilol | Celecoxib | Chloroquine | Chlorpromazine | Cimetidine | Dexamethasone | Diazepam | Diclofenac | Dinoprostone | Disulfiram | Doxorubicin | Doxycycline | Enalapril | Estradiol | Ethinyl Estradiol | Etoposide | Gentamicins | ginsenoside Re | Glyburide | Histamine | Hydroxyurea | Indapamide | Ivermectin | Ketamine | Mefloquine | Melatonin | Memantine | Metformin | Methimazole | Methotrexate | Methoxychlor | Methylprednisolone | Metoprolol | Morphine | Mustard Gas | Mycophenolic Acid | Naloxone | Naltrexone | Nicotine | Norethindrone | Omeprazole | Paclitaxel | Penicillamine | Phenytoin | Plant Extracts | Primaquine | Rifampin | rofecoxib | Simvastatin | Sulindac | Tacrolimus | Tetracycline | Thalidomide | Thiabendazole | Timolol | Tramadol | Tretinoin | Trichloroethylene | Troglitazone | Troleandomycin | Ursodeoxycholic Acid | Valproic Acid | Verapamil | Warfarin   440
29. positive regulation of reactive oxygen species biosynthetic process Breast Neoplasms Inferred via 77 chemicals: 2-chloro-5-nitrobenzanilide | 3,3',4,5'-tetrahydroxystilbene | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | Acrylamide | Air Pollutants | allyl sulfide | Arsenic | Arsenic Trioxide | Ascorbic Acid | Atrazine | Benzene | Benzo(a)pyrene | Biological Products | bisphenol A | Bortezomib | Cadmium | Calcitriol | Chlorpyrifos | Cisplatin | Copper | Curcumin | Cyclosporine | Deferoxamine | Deoxyglucose | Dexamethasone | diallyl trisulfide | Dichlorodiphenyl Dichloroethylene | Dietary Fats | diethyl phthalate | Disulfiram | Docetaxel | Doxorubicin | epigallocatechin gallate | Epirubicin | Estradiol | Ethanol | Etoposide | Eugenol | Fenretinide | Formaldehyde | Fulvestrant | Gefitinib | Genistein | Grape Seed Proanthocyanidins | mancozeb | Manganese | Methotrexate | Methylcholanthrene | Methylene Chloride | Nickel | Niclosamide | Nitric Oxide | Oxygen | perfluorooctane sulfonic acid | perfluorooctanoic acid | pirarubicin | Plant Extracts | Plant Preparations | pterostilbene | Quercetin | Resveratrol | Rosiglitazone | RTKI cpd | salicylaldehyde isonicotinoyl hydrazone | tanshinone | Tetrachlorodibenzodioxin | Tetrachloroethylene | Tobacco Smoke Pollution | Tretinoin | Trichloroethylene | Vehicle Emissions | Verapamil | Vitamin E | Water Pollutants, Chemical | Wortmannin | Zinc | Zoledronic Acid Inferred via 1 gene: MIR24-2 536
30. apoptotic process Skin Diseases Inferred via 76 chemicals: Aminolevulinic Acid | Amiodarone | Apomorphine | Arsenic | Arsenic Trioxide | Ascorbic Acid | azelaic acid | Betamethasone | Bexarotene | Bleomycin | Bortezomib | Capecitabine | Carboplatin | Chloroquine | Ciprofloxacin | Colchicine | Cyclophosphamide | Cytarabine | Dexamethasone | Diclofenac | Diltiazem | Disulfiram | Docetaxel | Doxorubicin | Doxycycline | Estradiol | Etoposide | Everolimus | Fluocinonide | Fluorouracil | Fluoxetine | Folic Acid | Gefitinib | Heparin | Homocysteine | Hydrocortisone | hydrocortisone-17-butyrate | Hydroxychloroquine | Hydroxyurea | Imiquimod | Indinavir | Indomethacin | Isotretinoin | Leucovorin | Lithium | Mechlorethamine | Melphalan | Mepivacaine | Methamphetamine | Methotrexate | Mitomycin | Mitoxantrone | Mustard Gas | Nanotubes, Carbon | Niacin | Paclitaxel | Penicillamine | Piroxicam | Plant Preparations | prednicarbate | Propofol | Riboflavin | Selenium | Sorafenib | tazarotene | Thalidomide | titanium dioxide | Tobacco Smoke Pollution | Tretinoin | Triclosan | Valproic Acid | Vemurafenib | Vincristine | Vitamin A | Vitamin E | Zidovudine Inferred via 10 genes: ERCC2 | FGFR2 | GADD45B | IER3 | IFNA2 | IL1A | IL1B | PTEN | TNF | ZFAND6 1291
31. cell proliferation Skin Diseases Inferred via 74 chemicals: 2,4-Dinitrophenol | Aminolevulinic Acid | Amiodarone | Arsenic | Arsenic Trioxide | Ascorbic Acid | benoxaprofen | Bleomycin | Bortezomib | Busulfan | Capecitabine | Carboplatin | Chloroquine | Ciprofloxacin | Colchicine | Contrast Media | Cyclophosphamide | Cytarabine | Dexamethasone | Diclofenac | Diltiazem | Disulfiram | Docetaxel | Doxorubicin | Estradiol | Etoposide | Everolimus | Flame Retardants | Fluocinolone Acetonide | Fluorouracil | Fluoxetine | Folic Acid | Gefitinib | Heparin | Homocysteine | Hydrocortisone | hydrocortisone-17-butyrate | Hydroxychloroquine | Hydroxyurea | Imiquimod | Indomethacin | Isotretinoin | Lithium | Mechlorethamine | Melphalan | Methamphetamine | Methotrexate | Mitomycin | Mitoxantrone | monomethylarsonous acid | Mustard Gas | N-(4-chlorophenyl)-1-((3-(furan-2-yl)phenyl)carbonyl)piperidine-3-carboxamide | Nanotubes, Carbon | Paclitaxel | palytoxin | Penicillamine | Plant Preparations | Platelet Activating Factor | Probenecid | pyrachlostrobin | Riboflavin | sodium arsenate | Sorafenib | Thalidomide | titanium dioxide | Tobacco Smoke Pollution | Tretinoin | Trichloroethylene | Triclosan | Valproic Acid | Vemurafenib | Vincristine | Vitamin A | Vitamin E Inferred via 5 genes: ERCC2 | IL1A | PTEN | TNF | USP13 893
32. regulation of blood pressure Angioedema Inferred via 73 chemicals: Acetaminophen | Acetylcysteine | Albuterol | Alprazolam | Amlodipine | Angiotensin-Converting Enzyme Inhibitors | Angiotensin Receptor Antagonists | Antihypertensive Agents | Apomorphine | Aspirin | benazepril | Bezafibrate | Bupropion | Calcitriol | Calcium Channel Blockers | candesartan | Celecoxib | Chloramphenicol | Chloroquine | Chlorthalidone | Cilazapril | Cimetidine | Cocaine | Desipramine | Diclofenac | Diltiazem | Diphenhydramine | Dipyridamole | Doxazosin | Droperidol | Enalapril | Epinephrine | Ethinyl Estradiol | Fluoxetine | Fosinopril | Glucocorticoids | Histamine | Hydrochlorothiazide | hydrochlorothiazide, lisinopril drug combination | Hydrocortisone | Ibuprofen | imidapril | Indomethacin | Irbesartan | Isradipine | Lidocaine | Lisinopril | Losartan | Meperidine | Methylprednisolone | Metoprolol | Naproxen | Nicardipine | Nifedipine | nimesulide | Nisoldipine | Nitroglycerin | Olmesartan Medoxomil | Oxygen | Perindopril | Propranolol | Pseudoephedrine | Quinapril | Ramipril | rofecoxib | Sirolimus | Sumatriptan | Tacrolimus | Telmisartan | Thiopental | trandolapril | Valsartan | Verapamil   1144
33. glutathione biosynthetic process Breast Neoplasms Inferred via 73 chemicals: 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin | 9,10-Dimethyl-1,2-benzanthracene | Acrylamide | Apigenin | Arsenic | Arsenic Trioxide | Ascorbic Acid | Atrazine | Benzene | Benzo(a)pyrene | bisphenol A | Bortezomib | Butylated Hydroxyanisole | Cadmium | Caffeine | Carmustine | Chloroquine | Chlorpyrifos | Cisplatin | Cobalt | Copper | Curcumin | Cyclophosphamide | Cyclosporine | DDT | Decitabine | Dexamethasone | Dietary Fats | Diethylhexyl Phthalate | Diethylnitrosamine | Doxorubicin | epigallocatechin gallate | Epirubicin | Ethanol | Famotidine | Folic Acid | Formaldehyde | Genistein | gingerol | Grape Seed Proanthocyanidins | Hexachlorobenzene | Hexachlorocyclohexane | indole-3-carbinol | Indomethacin | kaempferol | Malathion | Manganese | Mesna | Methotrexate | Methylcholanthrene | Nickel | Nicotine | ochratoxin A | Organoselenium Compounds | Orlistat | Oxygen | perfluorooctane sulfonic acid | Plant Extracts | Plant Preparations | Quercetin | Resveratrol | Rosiglitazone | Selenium | Smoke | Sulfasalazine | tangeretin | Testosterone | Tetrachlorodibenzodioxin | Tobacco Smoke Pollution | Vehicle Emissions | Vitamin E | Water Pollutants, Chemical | Zinc   584
34. membrane lipid catabolic process Breast Neoplasms Inferred via 72 chemicals: 9,10-Dimethyl-1,2-benzanthracene | allyl sulfide | Anthracyclines | Arsenic | Ascorbic Acid | Aspirin | Atropine | Benzene | Benzo(a)pyrene | beta-Naphthoflavone | bisphenol A | Butylated Hydroxyanisole | Cadmium | Capsaicin | Carmustine | Carubicin | Catechin | Celecoxib | Cisplatin | Copper | Curcumin | Cyclophosphamide | Cyclosporine | Deferoxamine | Dexamethasone | Diethylhexyl Phthalate | Diethylnitrosamine | Diethylstilbestrol | Disulfiram | Doxorubicin | Epirubicin | Estradiol | Ethanol | Hexachlorocyclohexane | Indomethacin | Leucovorin | Levamisole | Malathion | Manganese | Masoprocol | Methylcholanthrene | Mitomycin | Niacin | Nickel | Nicotine | nimesulide | Nitric Oxide | Nitrogen Dioxide | Nitroglycerin | ochratoxin A | Oxygen | Plant Extracts | Plant Preparations | Quercetin | Razoxane | Reserpine | Resveratrol | Rosiglitazone | Selenium | Smoke | Tamoxifen | Testosterone | Tetrachlorodibenzodioxin | Tobacco Smoke Pollution | Toremifene | Toxaphene | Tretinoin | Tungsten | Ubiquinone | Vitamin E | Water Pollutants, Chemical | Zinc Inferred via 1 gene: CYP1B1 815
35. regulation of blood pressure Pruritus Inferred via 72 chemicals: Acetaminophen | Air Pollutants, Occupational | Amitriptyline | Amlodipine | Angiotensin-Converting Enzyme Inhibitors | Antihypertensive Agents | Aspirin | Atorvastatin | Baclofen | Betamethasone | Bupivacaine | Bupropion | Capsaicin | Carvedilol | Celecoxib | Chlordiazepoxide | Chloroquine | Chlorpheniramine | Chlorpromazine | Cimetidine | Cinacalcet | Cyproheptadine | Dexamethasone | Diazepam | Diclofenac | Dinoprostone | Diphenhydramine | Disulfiram | Enalapril | Epinephrine | Ethinyl Estradiol | Ethinyl Estradiol-Norgestrel Combination | Fentanyl | Fosinopril | fosphenytoin | Glyburide | Histamine | Hydromorphone | Indapamide | Ketamine | Linezolid | Melatonin | Meperidine | Metformin | Methimazole | Methylprednisolone | Metoprolol | Mexiletine | Midodrine | Minoxidil | Morphine | Mycophenolic Acid | Nalbuphine | Naloxone | Naltrexone | Niacin | Nicotine | Penicillamine | Plant Extracts | Propofol | rofecoxib | Ropivacaine | Serotonin | Simvastatin | Sulindac | Sulpiride | Tacrolimus | Timolol | Troglitazone | Valproic Acid | Verapamil | Warfarin Inferred via 1 gene: TAC1 685
36. cell death Skin Diseases Inferred via 71 chemicals: 2,4-Dinitrophenol | 2-chloroethyl ethyl sulfide | Aminolevulinic Acid | Amiodarone | Apomorphine | Arsenic Trioxide | Ascorbic Acid | Azathioprine | Bleomycin | Bortezomib | Busulfan | Carbamazepine | Carboplatin | Chloroquine | Colchicine | Cyanamide | Cytarabine | dabrafenib | Dapsone | Dexamethasone | Diclofenac | Diltiazem | Disulfiram | Docetaxel | Doxorubicin | Doxycycline | Enoxaparin | Estradiol | Etoposide | Everolimus | Flame Retardants | Fluorouracil | Fluoxetine | Gefitinib | Heparin | Homocysteine | Hydroxyurea | Indomethacin | Lithium | Melphalan | Methamphetamine | Methotrexate | Mitomycin | Mitoxantrone | monomethylarsonous acid | Mustard Gas | Nanotubes, Carbon | Paclitaxel | palytoxin | Penicillamine | Phenelzine | Piroxicam | Probenecid | Pyridoxine | Selenium | sodium arsenate | Sorafenib | Thalidomide | Timolol | titanium dioxide | Tobacco Smoke Pollution | Tretinoin | Triamcinolone Acetonide | Trichloroethylene | Triclosan | Valproic Acid | Vemurafenib | Vincristine | Vitamin A | Vitamin E | Zidovudine   384
37. superoxide dismutase activity Breast Neoplasms Inferred via 70 chemicals: 2,4,5,2',4',5'-hexachlorobiphenyl | 2-chloro-5-nitrobenzanilide | 2-Methoxyestradiol | 4-nonylphenol | 9,10-Dimethyl-1,2-benzanthracene | Acrylamide | Apigenin | Arsenic | Arsenic Trioxide | Ascorbic Acid | Atrazine | Benzo(a)pyrene | bisphenol A | Cadmium | Capsaicin | Chloroquine | Chlorpyrifos | Cisplatin | Copper | Curcumin | Cyclophosphamide | Cyclosporine | DDT | Dexamethasone | Dietary Fats | Diethylhexyl Phthalate | Diethylnitrosamine | Doxorubicin | epigallocatechin gallate | Epirubicin | Ethanol | Famotidine | Fluorouracil | Formaldehyde | Genistein | gingerol | Grape Seed Proanthocyanidins | indole-3-carbinol | Indomethacin | kaempferol | Malathion | Manganese | Methotrexate | mono-(2-ethylhexyl)phthalate | Nickel | Nicotine | ochratoxin A | Oleic Acid | Orlistat | Oxygen | perfluorooctane sulfonic acid | perfluorooctanoic acid | Pesticides | Plant Extracts | Plant Oils | Plant Preparations | Quercetin | Ranitidine | Resveratrol | Rosiglitazone | Selenium | Smoke | Styrene | tangeretin | Testosterone | Tobacco Smoke Pollution | Vehicle Emissions | Vitamin E | Water Pollutants, Chemical | Zinc Inferred via 2 genes: NQO1 | SOD2 593
38. cell proliferation Angioedema Inferred via 70 chemicals: 4-phenylenediamine | Acetaminophen | Acetylcysteine | Adrenal Cortex Hormones | Albuterol | Alendronate | Alprazolam | Amiodarone | Amlodipine | Aspirin | Astemizole | Budesonide | Calcitriol | candesartan | Celecoxib | Chloroquine | Cilazapril | Cimetidine | Ciprofloxacin | Clozapine | Cocaine | Desipramine | Diclofenac | Diltiazem | Dinoprost | Diphenhydramine | Dipyridamole | Doxazosin | Doxorubicin | Enalapril | Epinephrine | Estrogens | Ethinyl Estradiol | Everolimus | Fluorouracil | Fluoxetine | Glucocorticoids | Histamine | Hydrocortisone | Ibuprofen | Indomethacin | Isotretinoin | Isradipine | Itraconazole | Ketoconazole | Lidocaine | Losartan | Lovastatin | Methotrexate | Nicardipine | Nifedipine | nimesulide | Nisoldipine | Omeprazole | Oxygen | Paroxetine | Phenytoin | Prednisolone | Progesterone | Propranolol | Ramipril | rofecoxib | Salmeterol Xinafoate | Sirolimus | Sulfasalazine | Tacrolimus | Terfenadine | Thiopental | Trifluoperazine | Verapamil   756
39. apoptotic process Skin Neoplasms Inferred via 68 chemicals: 3-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | 8-bromocyclic GMP | Acetylcysteine | Acitretin | Apigenin | Arsenic | arsenite | Azacitidine | Benzo(a)pyrene | Butyric Acid | Caffeine | Calcitriol | Capsaicin | Carmustine | corosolic acid | Curcumin | Dacarbazine | deguelin | Dietary Fats | Docetaxel | Doxorubicin | Ellagic Acid | epigallocatechin gallate | Fenretinide | Gefitinib | Geraniin | gingerol | Glucose | Hydrogen Peroxide | Hydroxyurea | Iron | isosalipurposide | Isotretinoin | Lycopene | Masoprocol | Melphalan | Methotrexate | Methylnitronitrosoguanidine | Methylnitrosourea | mezerein | Niacinamide | Nicotine | nimesulide | Okadaic Acid | Oleanolic Acid | Paclitaxel | Plant Extracts | Quercetin | Resveratrol | sanguinarine | Silymarin | Sirolimus | sodium arsenite | Tacrolimus | tert-Butylhydroperoxide | Tetrachlorodibenzodioxin | Tetradecanoylphorbol Acetate | Thapsigargin | tipifarnib | Tobacco Smoke Pollution | Tretinoin | Troglitazone | Tunicamycin | ursolic acid | Vincristine | YH 439 | Zidovudine Inferred via 16 genes: AKT1 | CASP8 | CSNK2A1 | CSNK2A2 | ERBB4 | ERCC2 | GJA1 | HCAR2 | HRAS | IL1A | NOTCH2 | PPARD | PTK2B | TGFBR1 | TP53 | TRP53 1242
40. DNA damage response, detection of DNA damage Breast Neoplasms Inferred via 68 chemicals: 2,3-bis(3'-hydroxybenzyl)butyrolactone | 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine | 4-biphenylamine | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | 9,10-Dimethyl-1,2-benzanthracene | Acrylamide | Air Pollutants | Arsenic | Arsenic Trioxide | Ascorbic Acid | Atrazine | Benzo(a)pyrene | betulinic acid | bisphenol A | Bromodeoxyuridine | Butylated Hydroxyanisole | Cacodylic Acid | Cadmium | captafol | Cisplatin | Copper | Curcumin | Cyclophosphamide | Deferoxamine | Dexamethasone | diallyl trisulfide | Dietary Fats | Diethylhexyl Phthalate | Diethylnitrosamine | Diethylstilbestrol | Doxorubicin | epigallocatechin gallate | Estradiol | Ethanol | Etoposide | Formaldehyde | Fulvestrant | Grape Seed Proanthocyanidins | indole-3-carbinol | kaempferol | mancozeb | Manganese | Masoprocol | Methylcholanthrene | methyleugenol | Methylnitrosourea | milbemycin | Mitomycin | Nickel | Niclosamide | Nicotine | ochratoxin A | Oxygen | Paclitaxel | perfluorooctane sulfonic acid | Plant Extracts | Polychlorinated Biphenyls | propylene dichloride | Quercetin | Resveratrol | RTKI cpd | Selenium | Vehicle Emissions | Vitamin E | Water Pollutants, Chemical | Wortmannin | Zidovudine | Zinc Inferred via 1 gene: PARP1 510
41. cell proliferation Urticaria Inferred via 67 chemicals: Acetaminophen | Adrenal Cortex Hormones | Allopurinol | Amiloride | Aspirin | Astemizole | Azithromycin | Benzoic Acid | Caffeine | Celecoxib | Cimetidine | cinnamic aldehyde | Ciprofloxacin | Cytarabine | Dexamethasone | Diatrizoate | Diclofenac | Diltiazem | Dimethyl Sulfoxide | Diphenhydramine | Doxorubicin | Epinephrine | Etoposide | Eugenol | Fluoxetine | Flurbiprofen | Formaldehyde | Furosemide | Histamine | Hydrocortisone | Hydroxychloroquine | Ibuprofen | Indomethacin | Isotretinoin | Itraconazole | Ketoconazole | Lansoprazole | Lidocaine | Losartan | Lovastatin | Mannitol | Meloxicam | Methimazole | Minocycline | Nevirapine | Nifedipine | Niflumic Acid | nimesulide | Ofloxacin | Omeprazole | Paroxetine | Pemetrexed | Penicillamine | Plant Extracts | Propylthiouracil | Quinidine | Ramipril | Ranitidine | Rifampin | Salmeterol Xinafoate | Sodium Benzoate | Sulfasalazine | Terfenadine | Thalidomide | Thiopental | Vitamin A | Vitamin E Inferred via 3 genes: IL18 | TGFB1 | TNF 487
42. apoptotic process Erythema Inferred via 67 chemicals: Aminolevulinic Acid | Amoxicillin | Ascorbic Acid | Atenolol | Betamethasone | Capsaicin | Carboplatin | Carmustine | chromium hexavalent ion | cinnamic aldehyde | Ciprofloxacin | Cytarabine | Daunorubicin | delta-aminolevulinic acid methyl ester | Dexamethasone | Dextran Sulfate | Diatrizoate | Diclofenac | Dimethyl Sulfoxide | Dinoprostone | Docetaxel | Doxorubicin | Enalapril | Epirubicin | Etoposide | Everolimus | Fluorouracil | gemcitabine | Hexachlorophene | Histamine | Hydroxyurea | Imiquimod | Isotretinoin | Leucovorin | Lidocaine | liposomal doxorubicin | Mesalamine | Methotrexate | Methylprednisolone | Minocycline | Mitomycin | Mometasone Furoate | Mustard Gas | Naltrexone | Niacin | Nicotine | Nitroprusside | Oxaliplatin | Paclitaxel | Phenytoin | pimecrolimus | Plant Extracts | Plant Preparations | Potassium Chloride | Propylthiouracil | Resveratrol | Stavudine | Sulfasalazine | Temozolomide | temsirolimus | Tetradecanoylphorbol Acetate | Thiopental | Tretinoin | Trinitrobenzenesulfonic Acid | Vancomycin | Vincristine | Vinorelbine   1058
43. response to oxidative stress Exanthema Inferred via 65 chemicals: Acetaminophen | Amifostine | Amiodarone | Amlodipine | Angiotensin-Converting Enzyme Inhibitors | Arsenic Trioxide | Aspirin | Atenolol | Azathioprine | Azithromycin | Budesonide | Ceftriaxone | Celecoxib | Cephaloridine | Chloramphenicol | Cisplatin | Clozapine | Cocaine | Cyclophosphamide | Cyclosporine | Dapsone | Dexamethasone | Diazoxide | Diclofenac | Diltiazem | Disulfiram | Enalapril | Everolimus | Gentamicins | Glutathione | Glyburide | Imipramine | Indomethacin | Isoniazid | Isotretinoin | Lithium | Lovastatin | Mercury | Methimazole | Minocycline | Morphine | Naproxen | Nelfinavir | Niacin | Nicotine | Nifedipine | Ozone | Particulate Matter | Pemetrexed | Penicillamine | Pentoxifylline | Phenobarbital | Propofol | Propranolol | Propylthiouracil | Quinidine | Sirolimus | Sorafenib | Sulfasalazine | Sulindac | Thalidomide | Thymidine | Valproic Acid | Vancomycin | Vehicle Emissions   304
44. cell proliferation Erythema Inferred via 64 chemicals: Aminolevulinic Acid | Ascorbic Acid | Atenolol | Capsaicin | Carboplatin | Carmustine | chromium hexavalent ion | cinnamic aldehyde | Ciprofloxacin | Cytarabine | Daunorubicin | Dexamethasone | Dextran Sulfate | Diatrizoate | Diclofenac | Dimethyl Sulfoxide | Dinitrochlorobenzene | Dinoprostone | Docetaxel | Doxorubicin | efavirenz | Enalapril | Epoprostenol | Etoposide | Everolimus | Fluorouracil | Freund's Adjuvant | Fullerenes | gemcitabine | gemtuzumab | Histamine | Hydroxyurea | Imiquimod | Isotretinoin | Lidocaine | liposomal doxorubicin | Methotrexate | Minocycline | Mitomycin | Mustard Gas | N-((4-dimethylaminophenyl)methyl)-N-(4-isopropylphenyl)-7-methoxy-1,2,3,4-tetrahydronaphthalen-1-carboxamide | Naltrexone | Nevirapine | Nicotine | Nitroprusside | Oxaliplatin | Paclitaxel | Phenytoin | pimecrolimus | Plant Extracts | Plant Preparations | Propylthiouracil | Resveratrol | Sodium Dodecyl Sulfate | Sulfasalazine | Temozolomide | temsirolimus | Tetradecanoylphorbol Acetate | Thiopental | Tretinoin | Trichloroethylene | Trinitrobenzenesulfonic Acid | Vincristine | Vinorelbine   752
45. cell death Angioedema Inferred via 64 chemicals: 4-phenylenediamine | Acetaminophen | Acetylcysteine | Albuterol | Amiodarone | Amlodipine | Apomorphine | Aspirin | Azathioprine | Bezafibrate | Bupropion | Calcitriol | Carbamazepine | Celecoxib | Chloramphenicol | Chloroquine | Cimetidine | Clozapine | Cocaine | Desipramine | Diclofenac | Diltiazem | Dipyridamole | Doxorubicin | Enalapril | Enoxaparin | Epirubicin | Estrogens | Ethinyl Estradiol | Everolimus | Fluorouracil | Fluoxetine | Glucocorticoids | Histamine | Hydrochlorothiazide | Ibuprofen | Indomethacin | Itraconazole | Ketoconazole | Ketoprofen | Lidocaine | Losartan | Lovastatin | Methotrexate | Methylprednisolone | Metoprolol | Nicardipine | Nifedipine | nimesulide | Omeprazole | Oxygen | Phenytoin | Piroxicam | Primaquine | Progesterone | Propranolol | rofecoxib | Sirolimus | Tacrolimus | Thiopental | Tolmetin | Tramadol | Trifluoperazine | Verapamil   412
46. response to oxidative stress Stevens-Johnson Syndrome Inferred via 63 chemicals: Acetaminophen | Alprazolam | Amifostine | Amiodarone | Angiotensin-Converting Enzyme Inhibitors | Atorvastatin | Azithromycin | Bortezomib | Carvedilol | Cefepime | Ceftriaxone | Celecoxib | Cilostazol | Citalopram | Cladribine | Clozapine | Cyclophosphamide | Cyclosporine | Diclofenac | Diltiazem | Docetaxel | Doxorubicin | Enalapril | fludarabine | Fluoxetine | Fluvastatin | Indomethacin | Isotretinoin | Losartan | Lovastatin | Mefloquine | Meloxicam | Minocycline | Naproxen | Nifedipine | Nitric Oxide | Nitrofurantoin | Pemetrexed | Penicillamine | Phenobarbital | Pravastatin | Propranolol | Propylthiouracil | Quetiapine Fumarate | Ramipril | Rifampin | Ritonavir | rofecoxib | Rosiglitazone | Saquinavir | Simvastatin | Sorafenib | Spironolactone | Sulfasalazine | Sulindac | Tacrolimus | Tadalafil | Tamoxifen | Thalidomide | Tolmetin | Topiramate | Valproic Acid | Vancomycin   161
47. reactive oxygen species metabolic process Breast Neoplasms Inferred via 62 chemicals: 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin | 9,10-Dimethyl-1,2-benzanthracene | allyl sulfide | Apigenin | Arsenic | Arsenic Trioxide | Ascorbic Acid | Atrazine | Benzo(a)pyrene | beta-Naphthoflavone | Biological Products | bisphenol A | Butylated Hydroxyanisole | Cadmium | Capsaicin | Chloroquine | Chlorpyrifos | Copper | Curcumin | DDT | Deferoxamine | Dexamethasone | diallyl trisulfide | Diethylnitrosamine | diethyl phthalate | Diethylstilbestrol | Doxorubicin | epigallocatechin gallate | Estradiol | Ethanol | Etoposide | Fulvestrant | Genistein | gingerol | Hexachlorobenzene | Hydrocarbons, Chlorinated | kaempferol | Manganese | Methylcholanthrene | mono-(2-ethylhexyl)phthalate | Nickel | Nicotine | Nitric Oxide | ochratoxin A | Oleic Acid | Oxygen | Phytoestrogens | Plant Extracts | Plant Preparations | pterostilbene | Quercetin | Resveratrol | Rosiglitazone | Selenium | Smoke | Tobacco Smoke Pollution | Vehicle Emissions | Verapamil | Vitamin E | Vorinostat | Wortmannin | xanthatin Inferred via 4 genes: BCL2 | CAT | NDUFS3 | SOD2 414
48. positive regulation of cell death Stevens-Johnson Syndrome Inferred via 62 chemicals: Acetaminophen | Amiodarone | Antineoplastic Agents | Atorvastatin | benazepril | Bortezomib | Carbamazepine | Celecoxib | cerivastatin | Chlorambucil | Cladribine | Clozapine | Cyclophosphamide | Cyclosporine | Diclofenac | Docetaxel | Doxorubicin | Erlotinib Hydrochloride | Etoposide | Fenofibrate | fludarabine | Fluoxetine | Fluvastatin | Fluvoxamine | Gefitinib | Ibuprofen | Ifosfamide | Indomethacin | Isotretinoin | Lansoprazole | Leflunomide | Levetiracetam | Lovastatin | Meloxicam | Methotrexate | montelukast | Naproxen | Nevirapine | Nifedipine | Nitric Oxide | Paclitaxel | Paroxetine | Pemetrexed | Phenobarbital | Phenytoin | Piroxicam | Pravastatin | Prednisolone | Propranolol | Propylthiouracil | Rifampin | Rosiglitazone | Sertraline | Simvastatin | Tacrolimus | Tamoxifen | telaprevir | Temozolomide | Thalidomide | Ticlopidine | Valproic Acid | Verapamil Inferred via 1 gene: EP300 161
49. lipid oxidation Breast Neoplasms Inferred via 62 chemicals: 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine | 4-nonylphenol | Acrylamide | Air Pollutants | Apigenin | Arsenic | Arsenic Trioxide | Ascorbic Acid | Aspirin | Atrazine | Benzo(a)pyrene | beta-Naphthoflavone | bisphenol A | Butylated Hydroxyanisole | Calcitriol | Carbamazepine | Catechin | Chlorpyrifos | Cisplatin | Clioquinol | Copper | Curcumin | Cyclophosphamide | Cyclosporine | Dexamethasone | diallyl trisulfide | Dietary Fats | Diethylnitrosamine | Doxorubicin | epigallocatechin gallate | Estradiol | estradiol 3-benzoate | Ethanol | Eugenol | Genistein | Grape Seed Proanthocyanidins | Indomethacin | isoliquiritigenin | Lignans | mancozeb | Masoprocol | Methotrexate | Methylcholanthrene | Nickel | ochratoxin A | Oxygen | perfluorooctanoic acid | Pesticides | Plant Extracts | Quercetin | Resveratrol | Rosiglitazone | Selenium | Sulfasalazine | Tamoxifen | Testosterone | Tobacco Smoke Pollution | Vehicle Emissions | Vincristine | Vitamin E | Water Pollutants, Chemical | Zinc   643
50. cell death Skin Neoplasms Inferred via 62 chemicals: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | 9,10-Dimethyl-1,2-benzanthracene | Acetylcysteine | Apigenin | arsenite | Azacitidine | Benzo(a)pyrene | Butyric Acid | Cacodylic Acid | Caffeine | Calcitriol | Capsaicin | Carmustine | cumene hydroperoxide | Curcumin | Dacarbazine | deguelin | Dichloroacetic Acid | Dietary Fats | Docetaxel | Doxorubicin | Dust | Ellagic Acid | epigallocatechin gallate | Erythrosine | Eugenol | Fenretinide | Gefitinib | Glucose | Hydrogen Peroxide | Hydroxyurea | Iron | mancozeb | Masoprocol | Melphalan | Methotrexate | monomethylarsonous acid | Nicotine | nimesulide | Okadaic Acid | Oleanolic Acid | Paclitaxel | Plant Extracts | Polylactic Acid-Polyglycolic Acid Copolymer | pterostilbene | Quercetin | Resveratrol | sanguinarine | Sirolimus | sodium arsenite | Tacrolimus | tert-Butylhydroperoxide | Tetrachlorodibenzodioxin | Tetradecanoylphorbol Acetate | Thapsigargin | Tobacco Smoke Pollution | Tretinoin | Troglitazone | Tunicamycin | ursolic acid | Vincristine | Zidovudine   482
1–50 of 113,483 results.